The molecular genetics of thalassemia.

No abstract is available for this paper.

• Publication year

  1981

• Venue

  Advances in human genetics

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1007/978-1-4615-8303-5_4PMID 6267910
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Heterogeneity of DNA deletion in gamma delta beta-thalassemia.

  1981cited by this paper
• γ-β-Thalassaemia studies showing that deletion of the γ- and δ-genes influences β-globin gene expression in man

  1980cited by this paper
• The 3' untranslated regions of the duplicated human alpha-globin genes are unexpectedly divergent.

  1980cited by this paper
• A novel α-globin gene arrangement in man

  1980cited by this paper
• gamma-beta-Thalassaemia studies showing that deletion of the gamma- and delta-genes influences beta-globin gene expression in man.

  1980cited by this paper
• Identification of regulatory sequences in the prelude sequences of an H2A histone gene by the study of specific deletion mutants in vivo.

  1980cited by this paper
• Polymorphism of DNA Sequence in the β-Globin Gene Region

  1980cited by this paper
• A novel alpha-globin gene arrangement in man.

  1980cited by this paper
• Coexistence of three hemoglobins with different alpha-chains in two unrelated children (with family studies indicating polymorphism in the number of alpha-globin genes in the Sardinian population).

  1980cited by this paper
• The β-globin gene is on the short arm of human chromosome 11

  1980cited by this paper
• Molecular cloning and characterization of the human β-like globin gene cluster

  1980cited by this paper
• Evolution of the hemoglobin S and C genes in world populations.

  1980cited by this paper
• Characterization of globin domains: heme binding to the central exon product.

  1980cited by this paper
• Rapid duplication and loss of genes coding for the alpha chains of hemoglobin.

  1980cited by this paper
• Triplicated alpha-globin loci in humans.

  1980cited by this paper
• Nucleotide sequence of the coding portion of human alpha globin messenger RNA.

  1980cited by this paper
• Polymorphism of DNA sequence in the beta-globin gene region. Application to prenatal diagnosis of beta 0 thalassemia in Sardinia.

  1980cited by this paper
• Specific in vitro initiation of transcription on conalbumin and ovalbumin genes and comparison with adenovirus-2 early and late genes

  1980cited by this paper
• DNA methylation in the human gamma delta beta-globin locus in erythroid and nonerythroid tissues.

  1980cited by this paper
• The detection and use of hemoglobin mutants in the direct analysis of human globin genes.

  1980cited by this paper
• Molecular cloning and characterization of the human beta-like globin gene cluster.

  1980cited by this paper
• Intervening sequences divide the gene for the constant region of mouse immunoglobulin mu chains into segments, each encoding a domain.

  1980cited by this paper
• Two different molecular organizations account for the single alpha-globin gene of the alpha-thalassemia-2 genotype.

  1980cited by this paper
• DNA methylation in the human γδβ-globin locus in erythroid and nonerythroid tissues

  1980cited by this paper
• Partial deletion of the α-globin structural gene in human α-thalassaemia

  1980cited by this paper
• The beta-globin gene is on the short arm of human chromosome 11.

  1980cited by this paper
• The organization of repetitive sequences in a cluster of rabbit beta-like globin genes.

  1980cited by this paper
• Physical mapping of the globin gene deletion in hereditary persistence of foetal haemoglobin (HPFH).

  1980cited by this paper
• A mechanism for RNA splicing.

  1980cited by this paper
• Partial deletion of the alpha-globin structural gene in human alpha-thalassaemia.

  1980cited by this paper
• Gene deletions in alpha thalassemia prove that the 5' zeta locus is functional.

  1980cited by this paper
• The chromosomal arrangement of human α-like globin genes: Sequence homology and α-globin gene deletions

  1980cited by this paper
• The ovalbumin gene-sequence of putative control regions

  1980cited by this paper
• Comparative analysis of the structural organization of two closely related vitellogenin genes in X. laevis.

  1980cited by this paper
• Prenatal diagnosis of sickle cell anemia by restriction and endonuclease analysis: HindIII polymorphisms in gamma-globin genes extend test applicability.

  1980cited by this paper
• Unequal crossing-over: a common basis of single alpha-globin genes in Asians and American blacks with hemoglobin-H disease.

  1980cited by this paper
• The chromosomal arrangement of human alpha-like globin genes: sequence homology and alpha-globin gene deletions.

  1980cited by this paper
• Processing of human beta-globin mRNA precursor to mRNA is defective in three patients with beta+-thalassemia.

  1980cited by this paper
• Beta Thalassemia: mutations which affect processing of the beta-Globin mRNA precursor.

  1980cited by this paper
• Beta thalassemia: Mutations which affect processing of the β-globin mRNA precursor

  1980cited by this paper
• Unusual alpha-globin-like gene that has cleanly lost both globin intervening sequences.

  1980cited by this paper
• Heterogeneity in the molecular basis of hereditary persistence of fetal haemoglobin

  1980cited by this paper
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• Analysis of the closely linked adult chicken alpha-globin genes in recombinant DNAs.

  1980cited by this paper
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  1980cited by this paper
• Are snRNPs involved in splicing?

  1980cited by this paper
• DNA-dependent transcription of adenovirus genes in a soluble whole-cell extract.

  1980cited by this paper
• Cloning and direct examination of a structurally abnormal human beta 0-thalassemia globin gene.

  1980cited by this paper
• Model for antenatal diagnosis of β-thalassaemia and other monogenic disorders by molecular analysis of linked DNA polymorphisms

  1980cited by this paper
• Transformation of mammalian cells with genes from procaryotes and eucaryotes.

  1979cited by this paper
• Rabbit beta-globin mRNA production in mouse L cells transformed with cloned rabbit beta-globin chromosomal DNA.

  1979cited by this paper
• Restriction enzyme analysis of the beta-globin gene in DNA from beta 0-thalassaemic subjects from Ferrara.

  1979cited by this paper
• beta 0 thalassemia, a nonsense mutation in man.

  1979cited by this paper
• Expression of the chromosomal mouse Beta maj-globin gene cloned in SV40.

  1979cited by this paper
• Introduction and expression of a rabbit beta-globin gene in mouse fibroblasts.

  1979cited by this paper
• Deletion of the A gamma-globin gene in G gamma-delta beta-thalassemia.

  1979cited by this paper
• Hereditary persistence of fetal haemoglobin (HPFH) and delta beta thalassaemia.

  1979cited by this paper
• The structure and evolution of the two nonallelic rat preproinsulin genes.

  1979cited by this paper
• Comparison of total sequence of a cloned rabbit beta-globin gene and its flanking regions with a homologous mouse sequence.

  1979cited by this paper
• Further studies of the frequency and significance of the Tgamma-chain of human fetal hemoglobin.

  1979cited by this paper
• Characterisation of deletions which affect the expression of fetal globin genes in man

  1979cited by this paper
• SV40 recombinants carrying a functional RNA splice junction and polyadenylation site from the chromosomal mouse beta maj globin gene.

  1979cited by this paper
• K562 human leukaemic cells synthesise embryonic haemoglobin in response to haemin

  1979cited by this paper
• The evolution and sequence comparison of two recently diverged mouse chromosomal beta--globin genes.

  1979cited by this paper
• SV40 recombinants carrying rabbit beta-globin gene coding sequences.

  1979cited by this paper
• Restriction endonucleases, simian virus 40, and the new genetics.

  1979cited by this paper
• Expression of the chromosomal mouse βmaj-globin gene cloned in SV40

  1979cited by this paper
• The molecular basis of alpha-thalassemias: frequent occurrence of dysfunctional alpha loci among non-Asians with Hb H disease.

  1979cited by this paper
• Globin gene deletion in HPFH, delta (o) beta (o) thalassaemia and Hb Lepore disease.

  1979cited by this paper
• Recent developments in the molecular genetics of human hemoglobin.

  1979cited by this paper
• Globin gene deletion in HPFH, δ°β° thalassaemia and Hb Lepore disease

  1979cited by this paper
• DNA sequence variants in the G gamma-, A gamma-, delta- and beta-globin genes of man.

  1979cited by this paper
• alpha-Globin gene organisation in blacks precludes the severe form of alpha-thalassaemia.

  1979cited by this paper
• Suppression of the nonsense mutation in homozygous beta 0 thalassaemia.

  1979cited by this paper
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  1979cited by this paper
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  1979cited by this paper
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  1979cited by this paper
• Structure of the human G gamma-A gamma-delta-beta-globin gene locus.

  1979cited by this paper
• Structure of the human fetal globin gene locus

  1979cited by this paper
• Suppression of the nonsense mutation in homozygous β0 thalassaemia

  1979cited by this paper
• Occurrence of G gamma Hb F in Greek HPFH: analysis of heterozygotes and compound heterozygotes with beta thalassaemia.

  1979cited by this paper
• Heterogeneity of DNA fragments associated with the sickle-globin gene.

  1979cited by this paper
• Molecular structure and flanking nucleotide sequences of the natural chicken ovomucoid gene.

  1979cited by this paper
• Selective and accurate initiation of transcription at the Ad2 major late promotor in a soluble system dependent on purified RNA polymerase II and DNA.

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• The genetic behaviour of a cloned mouse ribosomal DNA segment mimics mouse ribosomal gene evolution.

  1979cited by this paper
• The linkage arrangement of four rabbit beta-like globin genes.

  1979cited by this paper
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• Domains and the hinge region of an immunoglobulin heavy chain are encoded in separate DNA segments

  1979cited by this paper
• Organization of the alpha-globin genes in the Chinese alpha-thalassemia syndromes.

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• RNA polymerase III transcriptional units are interspersed among human non-alpha-globin genes.

  1979cited by this paper
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  1979cited by this paper
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  1979cited by this paper
• Partial deletion of beta-globin gene DNA in certain patients with beta 0-thalassemia.

  1979cited by this paper
• Synthesis of rabbit β-globin in cultured monkey kidney cells following infection with a SV40 β-globin recombinant genome

  1979cited by this paper
• Synthesis of rabbit beta-globin in cultured monkey kidney cells following infection with a SV40 beta-globin recombinant genome.

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