Endothelial function, vascular reactivity and gender differences in the cardiovascular system.

No abstract is available for this paper.

• Publication year

  2002

• Venue

  Cardiovascular Research

• Publication date

  2002-02-15

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/S0008-6363(01)00473-4PMID 11861030
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Extraskeletal effects of estrogen and the prevention of atherosclerosis

  2005cited by this paper
• The protective effects of estrogen on the cardiovascular system.

  2002cited by this paper
• A double-blind, placebo-controlled, randomized clinical trial of transdermal dihydrotestosterone gel on muscular strength, mobility, and quality of life in older men with partial androgen deficiency.

  2001cited by this paper
• Oestradiol improves arterial endothelial function in healthy men receiving testosterone

  2001cited by this paper
• Polycystic Ovary Syndrome Is Associated With Endothelial Dysfunction

  2001cited by this paper
• Effect of Testosterone on Plaque Development and Androgen Receptor Expression in the Arterial Vessel Wall

  2001cited by this paper
• Androgenic anabolic steroids and arterial structure and function in male bodybuilders.

  2001cited by this paper
• Vascular Effects of Synthetic or Natural Progestagen Combined With Conjugated Equine Estrogen in Healthy Postmenopausal Women

  2001cited by this paper
• Tamoxifen Effects on Endothelial Function and Cardiovascular Risk Factors in Men With Advanced Atherosclerosis

  2001cited by this paper
• Evidence that parenteral testosterone therapy may improve endothelium-dependent and -independent vasodilation in postmenopausal women already receiving estrogen.

  2001cited by this paper
• Androgen receptor expression is greater in macrophages from male than from female donors. A sex difference with implications for atherogenesis.

  2000cited by this paper
• Testing for endothelial dysfunction

  2000cited by this paper
• Long-term follow-up of patients with mild coronary artery disease and endothelial dysfunction.

  2000cited by this paper
• Differential Effects of Oral and Transdermal Estrogen Replacement Therapy on Endothelial Function in Postmenopausal Women

  2000cited by this paper
• Prognostic impact of coronary vasodilator dysfunction on adverse long-term outcome of coronary heart disease.

  2000cited by this paper
• Human megakaryocytes and platelets contain the estrogen receptor beta and androgen receptor (AR): testosterone regulates AR expression.

  2000cited by this paper
• Phytoestrogens do not influence lipoprotein levels or endothelial function in healthy, postmenopausal women.

  2000cited by this paper
• Protective effects of estrogen on the cardiovascular system.

  1999cited by this paper
• Acute administration of 17beta-oestradiol does not improve endothelium-dependent vasodilatation in young men.

  1999cited by this paper
• Constantly low HDL-cholesterol concentration relates to endothelial dysfunction and increased in vivo LDL-oxidation in healthy young men.

  1999cited by this paper
• Raloxifene acutely relaxes rabbit coronary arteries in vitro by an estrogen receptor-dependent and nitric oxide-dependent mechanism.

  1999cited by this paper
• Aromatase inhibition alters vascular reactivity and arterial compliance in men: a possible vascular role for endogenous sex hormones in males.

  1999cited by this paper
• Effects of testosterone on coronary vasomotor regulation in men with coronary heart disease.

  1999cited by this paper
• Vascular reactivity is impaired in genetic females taking high-dose androgens.

  1998cited by this paper
• Estradiol therapy combined with progesterone and endothelium-dependent vasodilation in postmenopausal women.

  1998cited by this paper
• Vascular endothelial growth factor is up-regulated in vitro and in vivo by androgens.

  1998cited by this paper
• Combined hormone replacement therapy does not protect women against the age-related decline in endothelium-dependent vasomotor function.

  1998cited by this paper
• Long-term estrogen therapy improves vascular function in male to female transsexuals.

  1997cited by this paper
• Gender difference in improvement of endothelium-dependent vasodilation after estrogen supplementation.

  1997cited by this paper
• Endothelial dysfunction: does it matter? Is it reversible?

  1997cited by this paper
• Androgen deprivation is associated with enhanced endothelium-dependent dilatation in adult men.

  1997cited by this paper
• Endothelial dysfunction in a man with disruptive mutation in oestrogen-receptor gene.

  1997cited by this paper
• Association between Polycystic Ovaries and Extent of Coronary Artery Disease in Women Having Cardiac Catheterization

  1997cited by this paper
• Soy isoflavones enhance coronary vascular reactivity in atherosclerotic female macaques.

  1997cited by this paper
• Systemic endothelial dysfunction is related to the extent and severity of coronary artery disease.

  1997cited by this paper
• Role of superoxide in angiotensin II-induced but not catecholamine-induced hypertension.

  1997cited by this paper
• Arterial reactivity is enhanced in genetic males taking high dose estrogens.

  1997cited by this paper
• 17 beta-estradiol regulation of human endothelial cell basal nitric oxide release, independent of cytosolic Ca2+ mobilization.

  1997cited by this paper
• Vascular endothelial growth factor

  1997cited by this paper
• In search of optimal long-term female hormone replacement: the potential of selective estrogen receptor modulators.

  1997cited by this paper
• Vascular endothelial growth factor is produced by peritoneal fluid macrophages in endometriosis and is regulated by ovarian steroids.

  1996cited by this paper
• Identification of authentic estrogen receptor in cultured endothelial cells. A potential mechanism for steroid hormone regulation of endothelial function.

  1996cited by this paper
• Nitric oxide as a challenge for the clinical chemistry laboratory.

  1996cited by this paper
• Endometrial vascular smooth muscle oestrogen and progesterone receptor distribution in women with and without menorrhagia.

  1996cited by this paper
• Hormone replacement therapy is associated with improved arterial physiology in healthy post‐menopausal women

  1996cited by this paper
• Gender differences in coronary artery diameter involve estrogen, nitric oxide, and Ca(2+)-dependent K+ channels.

  1996cited by this paper
• Androgen and estrogen receptors are present in primary cultures of human synovial macrophages.

  1996cited by this paper
• Normal ranges for brachial artery flow-mediated dilatation: A non-invasive ultrasound test of arterial endothelial function

  1996cited by this paper
• Testosterone induces dilation of canine coronary conductance and resistance arteries in vivo.

  1996cited by this paper
• The effect of cholesterol-lowering and antioxidant therapy on endothelium-dependent coronary vasomotion.

  1995cited by this paper
• 17 beta-Estradiol attenuates acetylcholine-induced coronary arterial constriction in women but not men with coronary heart disease.

  1995cited by this paper
• Estrogen increases endothelial nitric oxide by a receptor-mediated system.

  1995cited by this paper
• Nitric oxide is responsible for flow-dependent dilatation of human peripheral conduit arteries in vivo.

  1995cited by this paper
• Beneficial effects of cholesterol-lowering therapy on the coronary endothelium in patients with coronary artery disease.

  1995cited by this paper
• Testosterone relaxes rabbit coronary arteries and aorta.

  1995cited by this paper
• Estrogen relaxes coronary arteries by opening BKCa channels through a cGMP-dependent mechanism.

  1995cited by this paper
• Modulation of endothelium-dependent flow-mediated dilatation of the brachial artery by sex and menstrual cycle.

  1995cited by this paper
• Close relation of endothelial function in the human coronary and peripheral circulations.

  1995cited by this paper
• 17β-Estradiol Attenuates Acetylcholine-Induced Coronary Arterial Constriction in Women but Not Men With Coronary Heart Disease

  1995cited by this paper
• Chronic treatment with the anabolic steroid, nandrolone, inhibits vasodilator responses in rabbit aorta.

  1994cited by this paper
• Estrogen Improves Endothelium-Dependent, Flow-Mediated Vasodilation in Postmenopausal Women

  1994cited by this paper
• Aging is associated with endothelial dysfunction in healthy men years before the age-related decline in women.

  1994cited by this paper
• Human vascular smooth muscle cells contain functional estrogen receptor.

  1994cited by this paper
• Antioxidant potential of specific estrogens on lipid peroxidation.

  1994cited by this paper
• Myocardial Infarction and Coronary Deaths in the World Health Organization MONICA Project: Registration Procedures, Event Rates, and Case‐Fatality Rates in 38 Populations From 21 Countries in Four Continents

  1994cited by this paper
• Induction of calcium-dependent nitric oxide synthases by sex hormones.

  1994cited by this paper
• Role of endothelium in the maintenance of low pulmonary vascular tone in normal children.

  1994cited by this paper
• Effects of physiological levels of estrogen on coronary vasomotor function in postmenopausal women.

  1994cited by this paper
• Effects of Age on Endothelium‐Dependent Vasodilation of Resistance Coronary Artery by Acetycholine in Humans

  1993cited by this paper
• The pathogenesis of atherosclerosis: a perspective for the 1990s

  1993cited by this paper
• Antioxidant potential of specific estrogens on lipid peroxidation

  1993cited by this paper
• Endothelium-mediated coronary blood flow modulation in humans. Effects of age, atherosclerosis, hypercholesterolemia, and hypertension.

  1993cited by this paper
• Beneficial effect of oestrogen on exercise-induced myocardial ischaemia in women with coronary artery disease.

  1993cited by this paper
• Non-invasive detection of endothelial dysfunction in children and adults at risk of atherosclerosis.

  1992cited by this paper
• Endothelial Function in Human Coronary Arteries In Vivo: Focus on Hypercholesterolemia

  1991cited by this paper
• Long-term effects of methyl isocyanate.

  1989cited by this paper
• Effects of endothelium-derived nitric oxide on peripheral arteriolar tone in man.

  1989cited by this paper
• Endothelium and Control of Vascular Function State of the Art Lecture

  1989cited by this paper
• Cell biology of endothelial cells.

  1987cited by this paper
• Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

  1987cited by this paper
• Endothelium‐derived relaxing factor alters calcium fluxes in rabbit aorta: a cyclic guanosine monophosphate‐mediated effect.

  1986cited by this paper
• Crucial role of endothelium in the vasodilator response to increased flow in vivo.

  1986cited by this paper
• Choices among the Possible Reaction Routes Catalyzed by Thrombin a

  1986cited by this paper
• Paradoxical vasoconstriction induced by acetylcholine in atherosclerotic coronary arteries.

  1986cited by this paper
• Specific estrogen binding sites in human lymphoid cells and thymic cells.

  1983cited by this paper
• EIGHTH GADDUM MEMORIAL LECTURE UNIVERSITY OF LONDON INSTITUTE OF EDUCATION DECEMBER 1980: BIOLOGICAL IMPORTANCE OF PROSTACYCLIN

  1982cited by this paper
• The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine

  1980cited by this paper

• Evaluating the Impact of Active Footwear Systems on Vascular Health and Static Balance: An Exploratory Study

  2025cites this paper
• Age and gender-specific flow-mediated dilation reference values and predictive factors for Chinese children and adolescents

  2025cites this paper
• Increased Oxidative and Nitrative Stress and Decreased Sex Steroid Relaxation in a Vitamin D-Deficient Hyperandrogenic Rodent Model—And a Validation of the Polycystic Ovary Syndrome Model

  2025cites this paper
• Neurogenic Stunned Myocardium: A Narrative Review of Cardiopulmonary Failure Related to Subarachnoidal Haemorrhage

  2025cites this paper
• Measurement of Brachial Local Pulse Wave Velocity for Noninvasive Assessment of Endothelial Reactivity

  2025cites this paper
• Takotsubo Syndrome in Older Men　― Clinical Characteristics Differ by Sex and Age ―

  2024cites this paper
• Sex-Specific Responses of Central Artery Stiffness to Cold Pressor Test-mediated Sympathetic Activation.

  2024cites this paper
• Effects of vasoactive substances on biomechanics of small resistance arteries of male and female Dahl salt‐sensitive rats

  2024cites this paper
• Impact of Coronary Microvascular Dysfunction in Takotsubo Syndrome: Cause, Consequence or Both?

  2024cites this paper
• Psychosocial and psychopathological dimensions of patients with Takotsubo Syndrome.

  2024cites this paper
• Sex Differences in Outcomes of Acute Myocardial Injury After Stroke

  2024cites this paper
• Exploratory Review of the Takotsubo Syndrome and the Possible Role of the Psychosocial Stress Response and Inflammaging

  2024cites this paper
• Concurrent spontaneous coronary dissection and reversible cerebral vasoconstriction syndrome during postnatal care

  2024cites this paper
• Takotsubo syndrome: unravelling the enigma of the broken heart syndrome?—a narrative review

  2023cites this paper
• Stress Cardiomyopathy (Takotsubo)

  2023cites this paper
• Takotsubo Syndrome: The Secret Crosstalk between Heart and Brain

  2023cites this paper
• Sex differences in the renin-angiotensin-aldosterone system and its roles in hypertension, cardiovascular, and kidney diseases

  2023cites this paper
• Takotsubo syndrome: getting closer to its causes.

  2023cites this paper
• Female Reproductive Factors and Risk of New-Onset Heart Failure: Findings From UK Biobank.

  2023cites this paper
• Rethinking Tako-tsubo Cardiomyopathy: The Contribution of Myocardial Pathology and Molecular Imaging.

  2023cites this paper
• Transiently impaired endothelial function during thyroid hormone withdrawal in differentiated thyroid cancer patients

  2023cites this paper
• Stroke‐Heart Syndrome: Does Sex Matter?

  2023cites this paper
• Sexual Dimorphism in Cardiometabolic Diseases: The Role of AMPK

  2023cites this paper
• Crosstalk between high-density lipoproteins and endothelial cells in health and disease: Insights into sex-dependent modulation

  2022cites this paper
• The Octopus Trap of Takotsubo and Stroke: Genetics, Biomarkers and Clinical Management

  2022cites this paper
• The Impact of Mental Stress on Cardiovascular Health—Part II

  2022cites this paper
• Broken Heart Syndrome: Evolving Molecular Mechanisms and Principles of Management

  2022cites this paper
• Targeting Estrogen Signaling in the Radiation-induced Neurodegeneration: A Possible Role of Phytoestrogens

  2022cites this paper
• Heart-brain interactions in cardiac and brain diseases: why sex matters.

  2022cites this paper
• Sex Differences: Potential Impact in Vascular Physiopathology or Ischemic Heart Disease

  2022cites this paper
• Subarachnoidal hemorrhage related cardiomyopathy: an overview of Tako-Tsubo cardiomyopathy and related cardiac syndromes

  2022cites this paper
• Vitamin D Deficiency and Gender Alter Vasoconstrictor and Vasodilator Reactivity in Rat Carotid Artery

  2021cites this paper
• Takotsubo Cardiomyopathy and Nuclear Imaging

  2021cites this paper
• Dysregulation of nitric oxide synthases during early and late pathophysiological conditions of diabetes mellitus leads to amassing of microvascular impedement

  2021cites this paper
• Endothelin B receptor dysfunction mediates elevated myogenic tone in cerebral arteries from aged male Fischer 344 rats

  2021cites this paper
• Current Knowledge and Future Challenges in Takotsubo Syndrome: Part 1—Pathophysiology and Diagnosis

  2021cites this paper
• Chronic mercury exposure induces oxidative stress in female rats by endothelial nitric oxide synthase uncoupling and cyclooxygenase‐2 activation, without affecting oestrogen receptor function

  2021cites this paper
• Analysis of the effects of Zhenju antihypertensive tablet on efficacy, safety and vascular endothelial function in patients with essential hypertension

  2021cites this paper
• Cardiovascular Disease and the Menopause

  2020cites this paper
• 1 IBERIAN CURED-HAM CONSUMPTION IMPROVES ENDOTHELIAL 2 FUNCTION IN HEALTHY SUBJECTS 3 4

  2020cites this paper
• Peripheral vascular complication of transgender reassignment surgery.

  2020cites this paper
• Spontaneous coronary artery dissection: clinical implications and diagnostic challenges. Overlooked and underappreciated in Asia?

  2020cites this paper
• Estrogens and the Angiotensin II Type 2 Receptor Control Flow-Mediated Outward Remodeling in the Female Mouse Mesenteric Artery

  2020cites this paper
• Endothelial dysfunction is not associated with spontaneous coronary artery dissection.

  2020cites this paper
• Regulatory Actions of Estrogen Receptor Signaling in the Cardiovascular System

  2020influential citation
• Update of the Brazilian Guideline on Nuclear Cardiology - 2020

  2020cites this paper
• Plasma PCSK9 predicts microvascular function but not arterial stiffness in African-Americans with well controlled type 2 diabetes

  2020cites this paper
• Why Age Matters in Takotsubo Syndrome.

  2020cites this paper
• Vasculometabolic effects in patients with congenital growth hormone deficiency with and without GH replacement therapy during adulthood

  2020cites this paper
• The Great Myocardial Mimic - Takotsubo Syndrome.

  2020cites this paper
• [Endogenous and exogenous estrogens].

  2019cites this paper
• Umbilical cord length and rheumatic heart disease 2

  2019cites this paper
• Gender differences in microvascular function across muscles in the lower leg using blood-oxygen level dependent MR Imaging

  2019influential citation
• Trigger factors in takotsubo syndrome - A systematic review of case reports.

  2019cites this paper
• PROGNOSTIC PREDICTION OF CARDIOPULMONARY EXERCISE TEST PARAMETERS IN HEART FAILURE PATIENTS WITH ATRIAL FIBRILLATION

  2019cites this paper
• Spontaneous coronary artery dissection: etiology and recurrence

  2019cites this paper
• Sex does not influence impairments in popliteal endothelial-dependent vasodilator or vasoconstrictor responses following prolonged sitting.

  2019cites this paper
• Gender differences in cardiovascular risk of patients with Rheumatoid Arthritis.

  2019cites this paper
• Short-term exercise training reduces glycaemic variability and lowers circulating endothelial microparticles in overweight and obese women at elevated risk of type 2 diabetes

  2019cites this paper
• Acute Soy Supplementation Improves 20-km Time Trial Performance, Power, and Speed.

  2019cites this paper
• Molecular imaging of carotid artery atherosclerosis with PET: a systematic review

  2019cites this paper
• Trans-Endothelial Insulin Transport is Impaired in Skeletal Muscle Capillaries of Obese Male Mice

  2019cites this paper
• International Expert Consensus Document on Takotsubo Syndrome (Part I): Clinical Characteristics, Diagnostic Criteria, and Pathophysiology

  2018cites this paper
• Estrogen effects on arteries vary with stage of reproductive life and extent of subclinical atherosclerosis progression

  2018cites this paper
• The effects of resveratrol and exercise on age and gender‐dependent alterations of vascular functions and biomarkers

  2018cites this paper
• OP-EHEA180074 2032..2046

  2018cites this paper
• Age- and sex-dependent alteration of functions and epigenetic modifications of vessel and endothelium related biomarkers.

  2018cites this paper
• RXFP1 Receptor Activation by Relaxin-2 Induces Vascular Relaxation in Mice via a Gαi2-Protein/PI3Kß/γ/Nitric Oxide-Coupled Pathway

  2018cites this paper
• Novel interventional therapies to improve cardiovascular risk in women with polycystic ovary syndrome

  2018cites this paper
• Differences in Cardiovascular Aging in Men and Women.

  2018cites this paper
• Sex-Specific Analysis of Cardiovascular Function

  2018cites this paper
• Non-invasive technique for endothelial dysfunction assessment using a CBP-RPPG model in healthy and non-healthy subjects

  2018cites this paper
• The Impact of Estrogen Decline on Other Noncommunicable Diseases

  2017cites this paper
• Distance constraints on activation of TRPV4 channels by AKAP150-bound PKCα in arterial myocytes

  2017cites this paper
• Understanding blood pressure dynamics in the South African population: a latent variables approach to the analysis and comparison of data from multiple surveys

  2017cites this paper
• How does the estimated phase of menstrual cycle or menopause influence the prevalence of vasovagal syncope induced by head-up tilt test.

  2017cites this paper
• Spontaneous Coronary Artery Dissection Associated With Pregnancy.

  2017cites this paper
• Sex-specific computational models of the spontaneously hypertensive rat kidneys: factors affecting nitric oxide bioavailability.

  2017cites this paper
• Koronare Herzerkrankung – Unterschiede in Symptomatik und Verlauf bei Männern und Frauen

  2017cites this paper
• Assessing and Modifying Coronary Artery Disease Risk in Women

  2017cites this paper
• on TRPV4 channels by AKAP150-bound PKCα in arterial

  2017cites this paper
• Long‐term treatment with Nandrolone Decanoate impairs mesenteric vascular relaxation in both sedentary and exercised female rats

  2017cites this paper
• Membrane and Nuclear Estrogen Receptor Alpha Actions: From Tissue Specificity to Medical Implications.

  2017cites this paper
• Effect of hormone replacement therapy with the anti-mineralocorticoid progestin Drospirenone compared to tibolone on endothelial function and central haemodynamics in post-menopausal women.

  2017cites this paper
• Umbilical cord length and rheumatic heart disease 1 The relationship between umbilical cord length and chronic rheumatic heart disease : a prospective cohort study

  2017cites this paper
• JGP_201611709 639..660

  2017cites this paper
• Outstanding Effect of Physical Exercise on Endothelial Function Even in Children and Adolescents.

  2017cites this paper
• Effect of short-term colored-light exposure on cerebral hemodynamics and oxygenation, and systemic physiological activity

  2017cites this paper
• Tako-tsubo cardiomyopathy after a quarrel.

  2016cites this paper
• Sex‐related differences in reactivity of cerebral arterioles during moderate exercise training

  2016cites this paper
• Takotsubo Cardiomyopathy Following Cardiac Surgery

  2016cites this paper
• Factors that underlie the gender differences in cardiovascular diseases

  2016cites this paper
• The Sympathetic Nervous System in the Pathogenesis of Takotsubo Syndrome.

  2016cites this paper
• Assessment of arterial stiffness in type 1 diabetes using digital pulse contour analysis: Is it a reliable method?

  2016cites this paper
• Fetal programming of blood pressure in a transgenic mouse model of altered intrauterine environment

  2016cites this paper
• The Cardiovascular Effects of Chronic Hypoestrogenism

  2016cites this paper
• Hydroxytyrosol But Not Resveratrol Ingestion Induced an Acute Increment of Post Exercise Blood Flow in Brachial Artery

  2016cites this paper
• Examining Endothelial Function and Platelet Reactivity in Patients with Depression before and after SSRI Therapy

  2016cites this paper
• The sex differences in nature of vascular endothelial stress: nitrergic mechanisms

  2016cites this paper
• Arterial pressure beat to beat characterization during post-occlusive reactive hyperemia

  2016cites this paper