Attenuation of cochlear damage from noise trauma by an iron chelator, a free radical scavenger and glial cell line-derived neurotrophic factor in vivo.

No abstract is available for this paper.

• Publication year

  1999

• Venue

  Brain Research

• Publication date

  1999-01-09

• Fields of study

  Medicine, Chemistry, Environmental Science

• Identifiers
  DOI 10.1016/S0006-8993(98)01100-7PMID 9878807
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Appearance of free radicals in the guinea pig inner ear after noise-induced acoustic trauma

  2005cited by this paper
• Acquired resistance to acoustic trauma by sound conditioning is primarily mediated by changes restricted to the cochlea, not by systemic responses.

  1999cited by this paper
• The nitric oxide/cyclic GMP pathway: a potential major regulator of cochlear physiology.

  1998cited by this paper
• Free Radical Scavenging and Inhibition of Nitric Oxide Synthase Potentiates the Neurotrophic Effects of Brain-Derived Neurotrophic Factor on Axotomized Retinal Ganglion Cells In Vivo

  1998cited by this paper
• Guinea pig auditory neurons are protected by glial cell line-derived growth factor from degeneration after noise trauma.

  1998cited by this paper
• Direct evidence for the role of nitric oxide on the glutamate-induced neuronal death in cultured cortical neurons.

  1998cited by this paper
• Supplemental iron exacerbates aminoglycoside ototoxicity in vivo.

  1998cited by this paper
• Nitric Oxide and Superoxide Contribute to Motor Neuron Apoptosis Induced by Trophic Factor Deprivation

  1998cited by this paper
• Changes in cochlear antioxidant enzyme activity after sound conditioning and noise exposure in the chinchilla.

  1998cited by this paper
• Protection from gentamicin ototoxicity by iron chelators in guinea pig in vivo.

  1997cited by this paper
• Morphological evidence of ototoxicity of the iron chelator deferoxamine.

  1997cited by this paper
• Chronic strychnine administration into the cochlea potentiates permanent threshold shift following noise exposure.

  1997cited by this paper
• Glial Cell Line-Derived Neurotrophic Factor Protects against Ischemia-Induced Injury in the Cerebral Cortex

  1997cited by this paper
• Protection from Gentamicin Ototoxicity by Iron Chelators in Guinea Pig In Vivo

  1997cited by this paper
• The Efficacy of Direct and Adeno-associated Virus-mediated Introduction of Neurotrophin-3 in Preventing Neural Degeneration Following Aminoglycoside-induced Ototoxicity in the Guinea Pig

  1997cited by this paper
• Protection of both auditory hair cells and auditory neurons from cisplatin induced damage.

  1997cited by this paper
• R-phenylisopropyladenosine attenuates noise-induced hearing loss in the chinchilla.

  1997cited by this paper
• Defects in enteric innervation and kidney development in mice lacking GDNF

  1996cited by this paper
• Variable efficacy of radical scavengers and iron chelators to attenuate gentamicin ototoxicity in guinea pig in vivo.

  1996cited by this paper
• Characterization of drugs as antioxidant prophylactics.

  1996cited by this paper
• Pentoxifylline maintains cochlear microcirculation and attenuates temporary threshold shifts following acoustic overstimulation.

  1996cited by this paper
• Noise-induced cochlear hypoxia is intensity dependent, correlates with hearing loss and precedes reduction of cochlear blood flow.

  1996cited by this paper
• Formation of free radicals by gentamicin and iron and evidence for an iron/gentamicin complex.

  1995cited by this paper
• Protection and repair of the nigrostriatal dopaminergic system by GDNF in vivo

  1995cited by this paper
• Lipid peroxidation inhibitor attenuates noise-induced temporary threshold shifts.

  1994cited by this paper
• N-acetyl-L-cysteine is a pluripotent protector against cell death and enhancer of trophic factor-mediated cell survival in vitro.

  1994cited by this paper
• GDNF: a potent survival factor for motoneurons present in peripheral nerve and muscle.

  1994cited by this paper
• The Protective Effects of Allopurinol and Superoxide Dismutase on Noise-Induced Cochlear Damage

  1993cited by this paper
• Modulation of calcium current, intracellular calcium levels and cell survival by glucose deprivation and growth factors in hippocampal neurons.

  1993cited by this paper
• Glutathione S-transferases in the organ of Corti of the rat: enzymatic activity, subunit composition and immunohistochemical localization.

  1993cited by this paper
• Oxidative stress, glutamate, and neurodegenerative disorders.

  1993cited by this paper
• Expression of nitric-oxide synthase (NOS) in injured CNS neurons as shown by NADPH diaphorase histochemistry.

  1993cited by this paper
• GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons.

  1993cited by this paper
• Iron chelators in medicine.

  1992cited by this paper
• Nitric oxide mediates glutamate neurotoxicity in primary cortical cultures.

  1991cited by this paper
• TGFSS1 modulates bFGF receptor message expression in cultured adult auditory neurons.

  1991cited by this paper
• Excitatory amino acid release and free radical formation may cooperate in the genesis of ischemia-induced neuronal damage

  1990cited by this paper
• Antioxidants protect against glutamate-induced cytotoxicity in a neuronal cell line.

  1989cited by this paper
• Endothelium-derived relaxing factor release on activation of NMDA receptors suggests role as intercellular messenger in the brain

  1988cited by this paper
• Laser Doppler measurements of cochlear blood flow during loud sound exposure in the guinea pig.

  1987cited by this paper
• Ferric iron and superoxide ions are required for the killing of cultured hepatocytes by hydrogen peroxide. Evidence for the participation of hydroxyl radicals formed by an iron-catalyzed Haber-Weiss reaction.

  1985cited by this paper
• Role of metals in oxygen radical reactions.

  1985cited by this paper
• Sex differences in the cellular defence system against free radicals from oxygen or drug metabolites in rat

  1984cited by this paper
• Inhibition of the iron-catalysed formation of hydroxyl radicals from superoxide and of lipid peroxidation by desferrioxamine.

  1979cited by this paper

• PLGA nanoparticles in otoprotection and inner ear regeneration: a new frontier in nanomedicine for hearing disorders

  2025cites this paper
• Nanodelivery of antioxidant Agents: A promising strategy for preventing sensorineural hearing loss.

  2024cites this paper
• Deferoxamine protects cochlear hair cells and hair cell-like HEI-OC1 cells against tert-butyl hydroperoxide-induced ototoxicity.

  2024cites this paper
• D-methionine administered as late as 36 hours post-noise exposure rescues from permanent threshold shift and dose-dependently increases serum antioxidant levels

  2022cites this paper
• Local Long-Term Inner Ear Drug Delivery in Normal Hearing Guinea Pig—An Animal Model to Develop Preventive Treatment for Noise-Induced Hearing Loss

  2022cites this paper
• Frailty Syndrome and Oxidative Stress as Possible Links Between Age-Related Hearing Loss and Alzheimer’s Disease

  2022cites this paper
• Killer or helper? The mechanism underlying the role of adenylate activated kinase in sound conditioning

  2022cites this paper
• Multifunctional Redox Modulators Protect Auditory, Visual, and Cognitive Function

  2021cites this paper
• Cochlear Preconditioning as a Modulator of Susceptibility to Hearing Loss

  2021cites this paper
• Programmed cell death pathways in hearing loss: A review of apoptosis, autophagy and programmed necrosis

  2020cites this paper
• The impact of carbon monoxide inhalation on developing noise-induced hearing loss in guinea pigs

  2020cites this paper
• Novel oral multifunctional antioxidant prevents noise-induced hearing loss and hair cell loss.

  2020cites this paper
• Octave band noise exposure: Laboratory models and otoprotection efforts.

  2019cites this paper
• Virally Mediated Overexpression of Glial-Derived Neurotrophic Factor Elicits Age- and Dose-Dependent Neuronal Toxicity and Hearing Loss

  2019cites this paper
• The rat animal model for noise-induced hearing loss.

  2019cites this paper
• Use of the guinea pig in studies on the development and prevention of acquired sensorineural hearing loss, with an emphasis on noise.

  2019cites this paper
• An Oral Combination of Vitamins A, C, E, and Mg++ Improves Auditory Thresholds in Age-Related Hearing Loss

  2018cites this paper
• The adhesion molecule cadherin 11 is essential for acquisition of normal hearing ability through middle ear development in the mouse

  2018cites this paper
• 6.18 – Auditory Toxicology☆

  2018cites this paper
• An evidence-base and implementation framework for promoting best practices in pharmaceutical interventions for hearing loss (PIHL) research

  2017cites this paper
• Vestibular end organ injury induced by middle ear treatment with ferric chloride in rats

  2017cites this paper
• Olfactory epithelium neural stem cell implantation restores noise-induced hearing loss in rats.

  2016cites this paper
• Quercetin protects against hair cell loss in the zebrafish lateral line and guinea pig cochlea.

  2016cites this paper
• Dual Release Carriers for Cochlear Delivery

  2016cites this paper
• Synergistic effects of free radical scavengers and cochlear vasodilators: a new otoprotective strategy for age-related hearing loss

  2015cites this paper
• On the Distant Horizon--Medical Therapy for Sensorineural Hearing Loss.

  2015cites this paper
• Protection from noise-induced hearing loss with Src inhibitors.

  2015cites this paper
• Neurotrophic and antioxidant effects of silymarin comparable to 4-methylcatechol in protection against gentamicin-induced ototoxicity in guinea pigs

  2015cites this paper
• Antioxidants Reduce Cellular and Functional Changes Induced by Intense Noise in the Inner Ear and Cochlear Nucleus

  2014cites this paper
• Coenzyme Q10 Protects Hair Cells against Aminoglycoside

  2014cites this paper
• Effects of substance P during the recovery of hearing function after noise-induced hearing loss.

  2014cites this paper
• Erratum to: Antioxidants Reduce Cellular and Functional Changes Induced by Intense Noise in the Inner Ear and Cochlear Nucleus

  2014cites this paper
• A Review of Animal Studies for the Efficacy of D-Methionine in Reducing Threshold Shifts and Affecting Biochemical Changes after Exposure to Noise

  2014cites this paper
• A Review of Animal Studies for the Effic acy of D- Methionine in Reducing Thr eshold Shift s and Affec ting Biochemical Changes aft er Exposure to Noise

  2014cites this paper
• Attenuation of noise-induced hearing loss using methylene blue

  2014cites this paper
• Behavioral and Neural Discrimination of Speech Sounds After Moderate or Intense Noise Exposure in Rats

  2014cites this paper
• Resistance to Noise-Induced Hearing Loss in 129S6 and MOLF Mice: Identification of Independent, Overlapping, and Interacting Chromosomal Regions

  2014cites this paper
• Protective Effect of Silymarin on Noise-Induced Hearing Loss in Guinea Pigs

  2013cites this paper
• Reduction in impulse noise-induced permanent threshold shift with intracochlear application of an NADPH oxidase inhibitor.

  2013cites this paper
• Changes in the adult vertebrate auditory sensory epithelium after trauma.

  2013cites this paper
• Prophylactic and therapeutic functions of drug combinations against noise-induced hearing loss.

  2013cites this paper
• Age-Related Hearing Loss in Mn-SOD Heterozygous Knockout Mice

  2013cites this paper
• Developments in delivery of medications for inner ear disease

  2013cites this paper
• Geranylgeranylacetone suppresses noise-induced expression of proinflammatory cytokines in the cochlea.

  2012cites this paper
• Frontiers in the Treatment of Hearing Loss

  2012cites this paper
• 2 Prevention of Hearing Loss 2 . 1 Timing of Interventions for Preventing Hearing Loss

  2011influential citation
• Protective Effects of α-Tocopherol on ABR Threshold Shift in Rabbits Exposed to Noise and Carbon Monoxide

  2011cites this paper
• Low-Dose D-Methionine and N-Acetyl-L-Cysteine for Protection from Permanent Noise-Induced Hearing Loss in Chinchillas

  2011cites this paper
• Ototoxicity of styrene

  2011cites this paper
• Effects of delayed and extended antioxidant treatment on acute acoustic trauma

  2011cites this paper
• Protective role of Nrf2 in age-related hearing loss and gentamicin ototoxicity.

  2011cites this paper
• Efficacy of a combined drug therapy for ameliorating noise-induced hearing loss

  2011cites this paper
• Oxidative stress in spiral ganglion cells of pigmented and albino guinea pigs exposed to impulse noise

  2011influential citation
• Mechanisms of Noise-Induced Hearing Loss and Treatment

  2011cites this paper
• Effect of N-acetylcysteine in protecting from simultaneous noise and carbon monoxide induced hair cell loss

  2011cites this paper
• Postexposure treatment with a Src-PTK inhibitor in combination with N-l-acetyl cysteine to reduce noise-induced hearing loss.

  2011cites this paper
• Complementary Tinnitus Therapies

  2011cites this paper
• Protection from impulse noise-induced hearing loss with novel Src-protein tyrosine kinase inhibitors.

  2011cites this paper
• Pharmacologic and Molecular Therapies of the Cochlear and Vestibular Labyrinth

  2010cites this paper
• Development of an Embryonic Stem Cell-Based Therapy for Replacement of Spiral Ganglion Neurons.

  2010cites this paper
• Les nouvelles stratégies thérapeutiques du traumatisme sonore par bruit d'arme chez le cobaye

  2010cites this paper
• Ingestion of Korean Red Ginseng after Noise Exposure Can Potentiate Rapid Recovery of Hearing in Mice

  2010influential citation
• Effects of N-Acetylcysteine on Auditory Brainstem Response Threshold Shift in Rabbits Exposed to Noise and Carbon Monoxide

  2010cites this paper
• Hydrogen protects vestibular hair cells from free radicals

  2010cites this paper
• Protective effects of exogenous GM-1 ganglioside on acoustic injury of the mouse cochlea.

  2010cites this paper
• Chemical Screening for Hair Cell Loss and Protection in the Zebrafish Lateral Line

  2010cites this paper
• Effect of hydrogen peroxide on potassium currents in inner hair cells isolated from guinea pig cochlea

  2010cites this paper
• Oxidative stress in the cochlea: an update.

  2010cites this paper
• 13.14 – Auditory Toxicology*

  2010cites this paper
• The effects of glutathione enhancement on sensorineural hearing loss.

  2010cites this paper
• Racial Heritage/Melanin and Otoacoustic Emission Measures of Cochlear Function

  2009cites this paper
• Effect of vitamin C depletion on age-related hearing loss in SMP30/GNL knockout mice.

  2009cites this paper
• Gene therapy and stem cell transplantation: strategies for hearing restoration.

  2009cites this paper
• 마우스에서 고려 홍삼의 구강내 섭취를 통한 소음성 난청의 예방효과

  2009cites this paper
• Cell Death and Cochlear Protection

  2008cites this paper
• From cochlear cell death pathways to new pharmacological therapies.

  2008cites this paper
• Protective properties of antioxidant drugs in noise-induced hearing loss in the guinea pig

  2008cites this paper
• Gene Transfer in Human Vestibular Epithelia and the Prospects for Inner Ear Gene Therapy

  2008cites this paper
• Antioxidant protection against acoustic trauma by coadministration of idebenone and vitamin E

  2008cites this paper
• Lipoic acid and 6-formylpterin reduce potentiation of noise-induced hearing loss by carbon monoxide: preliminary investigation.

  2008cites this paper
• Effects of hydrogen peroxide on vestibular hair cells in the guinea pig: importance of cell membrane impairment preceding cell death

  2008cites this paper
• Susceptibilidade genética à perda auditiva induzida por ruído (PAIR)

  2008cites this paper
• Reversal of noradrenergic depletion and lipid peroxidation in the pons after brain injury correlates with motor function recovery in rats.

  2008cites this paper
• Localized cell and drug delivery for auditory prostheses.

  2008cites this paper
• Effect of water-soluble coenzyme Q10 on noise-induced hearing loss in guinea pigs

  2008cites this paper
• Effectiveness of 4-hydroxy phenyl N-tert-butylnitrone (4-OHPBN) alone and in combination with other antioxidant drugs in the treatment of acute acoustic trauma in chinchilla.

  2008cites this paper
• Relation between outer hair cell loss and hearing loss in rats exposed to styrene.

  2008cites this paper
• Free radical scavengers vitamins A, C, and E plus magnesium reduce noise trauma.

  2007cites this paper
• Pharmacological approaches to the prevention and treatment of cochlear injury due to noise

  2007cites this paper
• Promotion of noise-induced cochlear injury by toluene and ethylbenzene in the rat.

  2007cites this paper
• Creatine and tempol attenuate noise-induced hearing loss.

  2007cites this paper
• Administration of amitriptyline attenuates noise-induced hearing loss via glial cell line-derived neurotrophic factor (GDNF) induction.

  2007cites this paper
• NAC for noise: from the bench top to the clinic.

  2007cites this paper
• Protection from Noise-Induced Temporary Threshold Shift by d-Methionine is Associated with Preservation of ATPase Activities

  2007cites this paper
• The Effect of Isoflurane, Halothane and Pentobarbital on Noise-Induced Hearing Loss in Mice

  2007cites this paper
• Pharmacotherapy of the inner ear

  2007cites this paper
• Mechanisms of noise-induced hearing loss indicate multiple methods of prevention.

  2007cites this paper
• JP-8 jet fuel can promote auditory impairment resulting from subsequent noise exposure in rats.

  2007cites this paper
• Diffusion-Based Model for Noise-Induced Hearing Loss

  2007cites this paper
• Noise protection with N-acetyl-l-cysteine (NAC) using a variety of noise exposures, NAC doses, and routes of administration

  2007cites this paper