Copeptin in the diagnosis of vasopressin-dependent disorders of fluid homeostasis

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Nature Reviews Endocrinology

• Publication date

  2016-03-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1038/nrendo.2015.224PMID 26794439
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Clinical review

  2016cited by this paper
• Diagnostic Accuracy of Copeptin in the Differential Diagnosis of the Polyuria-polydipsia Syndrome: A Prospective Multicenter Study.

  2015cited by this paper
• Copeptin as a stress marker prior and after a written examination – the CoEXAM study

  2015cited by this paper
• CT-pro-AVP as a tool for assessment of intravascular volume depletion in severe hyponatremia.

  2015cited by this paper
• Postoperative Copeptin Concentration Predicts Diabetes Insipidus After Pituitary Surgery.

  2015cited by this paper
• Comparison between copeptin and vasopressin in a population from the community and in people with chronic kidney disease.

  2014cited by this paper
• A prospective multicenter study

  2014cited by this paper
• A copeptin-based classification of the osmoregulatory defects in the syndrome of inappropriate antidiuresis.

  2014cited by this paper
• Diagnosis, Evaluation, and Treatment of Hyponatremia: Expert Panel Recommendations

  2014cited by this paper
• Copeptin for the differential diagnosis and therapy management of hyponatremia in hospitalized patients - 'The Co-MED-Study'

  2014cited by this paper
• Copeptin concentrations during psychological stress: the PsyCo study.

  2014cited by this paper
• Kidney function and plasma copeptin levels in healthy kidney donors and autosomal dominant polycystic kidney disease patients.

  2014cited by this paper
• Copeptin levels are independent of ingested nutrient type after standardised meal administration – the CoMEAL study

  2014cited by this paper
• Dendritic peptide release mediates interpopulation crosstalk between neurosecretory and preautonomic networks.

  2013cited by this paper
• Diagnosis, evaluation, and treatment of hyponatremia: expert panel recommendations.

  2013cited by this paper
• Vasopressin, copeptin, and renal concentrating capacity in patients with autosomal dominant polycystic kidney disease without renal impairment.

  2012cited by this paper
• Clinical review: Current state and future perspectives in the diagnosis of diabetes insipidus: a clinical review.

  2012cited by this paper
• Copeptin in the differential diagnosis of the polydipsia-polyuria syndrome--revisiting the direct and indirect water deprivation tests.

  2011cited by this paper
• Correlation of plasma copeptin and vasopressin concentrations in hypo-, iso-, and hyperosmolar States.

  2011cited by this paper
• Vaptans for the treatment of hyponatremia

  2011cited by this paper
• Copeptin: a biomarker of cardiovascular and renal function.

  2010cited by this paper
• Hyperosmotic activation of CNS sympathetic drive: implications for cardiovascular disease

  2010cited by this paper
• Utility and limitations of the traditional diagnostic approach to hyponatremia: a diagnostic study.

  2010cited by this paper
• The stress hormone copeptin: a new prognostic biomarker in acute illness.

  2010cited by this paper
• Incremental value of copeptin for rapid rule out of acute myocardial infarction.

  2009cited by this paper
• Gender and renal function influence plasma levels of copeptin in healthy individuals.

  2009cited by this paper
• Hyponatremia-Induced Osteoporosis

  2009cited by this paper
• Hyponatremia treatment guidelines 2007: expert panel recommendations.

  2009cited by this paper
• Ontogeny of bovine neurohypophysial hormone precursors. II. Foetal copeptin, the third domain of the vasopressin precursor.

  2009cited by this paper
• Copeptin: A novel, independent prognostic marker in patients with ischemic stroke

  2009cited by this paper
• Copeptin in the differential diagnosis of hyponatremia.

  2008cited by this paper
• Value of fractional uric acid excretion in differential diagnosis of hyponatremic patients on diuretics.

  2008cited by this paper
• Central mechanisms of osmosensation and systemic osmoregulation

  2008cited by this paper
• COPEPTIN, A STABLE PEPTIDE OF THE ARGININE VASOPRESSIN PRECURSOR, IS ELEVATED IN HEMORRHAGIC AND SEPTIC SHOCK

  2007cited by this paper
• Anterior and posterior pituitary function testing with simultaneous insulin tolerance test and a novel copeptin assay.

  2007cited by this paper
• Successful long-term treatment of hyponatremia in syndrome of inappropriate antidiuretic hormone secretion with satavaptan (SR121463B), an orally active nonpeptide vasopressin V2-receptor antagonist.

  2006cited by this paper
• Tolvaptan, a selective oral vasopressin V2-receptor antagonist, for hyponatremia.

  2006cited by this paper
• Menstrual cycle symptoms are associated with changes in low‐grade inflammation

  2006cited by this paper
• Incidence and prevalence of hyponatremia.

  2006cited by this paper
• Molecular Transient Receptor Potential Vanilloid 1 Is Required for Intrinsic Osmoreception in Organum Vasculosum Lamina Terminalis Neurons and for Normal Thirst Responses to Systemic Hyperosmolality

  2006cited by this paper
• Mild chronic hyponatremia is associated with falls, unsteadiness, and attention deficits.

  2006cited by this paper
• Assay for the measurement of copeptin, a stable peptide derived from the precursor of vasopressin.

  2006cited by this paper
• Properties of human vasopressin precursor constructs: inefficient monomer folding in the absence of copeptin as a potential contributor to diabetes insipidus.

  2004cited by this paper
• Effect of primary polydipsia on aquaporin and sodium transporter abundance.

  2003cited by this paper
• Lectin control of protein folding and sorting in the secretory pathway.

  2003cited by this paper
• Hormone stability in human whole blood.

  2003cited by this paper
• Disorders of body water homeostasis.

  2003cited by this paper
• Dynamic processing of neuropeptides

  2002cited by this paper
• Baroregulation of vasopressin release in adipsic diabetes insipidus.

  2002cited by this paper
• Dynamic processing of neuropeptides: sequential conformation shaping of neurohypophysial preprohormones during intraneuronal secretory transport.

  2002cited by this paper
• Protein glucosylation and its role in protein folding.

  2000cited by this paper
• Improved extraction procedure and RIA for determination of arginine8-vasopressin in plasma: role of premeasurement sample treatment and reference values in children.

  1999cited by this paper
• Structure–Function Relationships of the Vasopressin Prohormone Domains

  1998cited by this paper
• Diabetes Insipidus

  1998cited by this paper
• Diabetes insipidus.

  1997cited by this paper
• Vasopressin and platelets: a concise review.

  1997cited by this paper
• Diabetes insipidus.

  1995cited by this paper
• Hyponatremia in hospitalized patients with the acquired immunodeficiency syndrome (AIDS) and the AIDS-related complex.

  1993cited by this paper
• A Highly Sensitive and Rapid Radioimmunoassay for the Determination of Argmine8-Vasopressin

  1992cited by this paper
• Mechanisms of subcellular cytosolic Ca2+ signaling evoked by stimulation of the vasopressin V1a receptor.

  1992cited by this paper
• Solid-phase extraction of plasma vasopressin: evaluation, validation and application.

  1991cited by this paper
• The vasopressin-associated glycopeptide is not a prolactin-releasing factor: studies with lactating Brattleboro rats.

  1989cited by this paper
• [Progress in endocrinology].

  1988cited by this paper
• The glycopeptide moiety of vasopressin-neurophysin precursor is neurohypophysial prolactin releasing factor.

  1988cited by this paper
• Physiology of ADH secretion.

  1987cited by this paper
• Clinical assessment of extracellular fluid volume in hyponatremia.

  1987cited by this paper
• Physiology of ADH secretion.

  1987cited by this paper
• Osmoregulation and control of vasopressin secretion in healthy humans.

  1987cited by this paper
• Diabetes insipidus in man

  1985cited by this paper
• Structural organization of the rat gene for the arginine vasopressin‐neurophysin precursor.

  1983cited by this paper
• Plasma and Platelet Vasopressin in Essential Hypertension and Congestive Heart Failure

  1983cited by this paper
• A comparison of diagnostic methods to differentiate diabetes insipidus from primary polyuria: a review of 21 patients.

  1983cited by this paper
• Modulation of stress-induced ACTH release by corticotropin-releasing factor, catecholamines and vasopressin

  1983cited by this paper
• Deduced amino acid sequence from the bovine oxytocin–neurophysin I precursor cDNA

  1983cited by this paper
• Corticotropin releasing activity of the new CRF is potentiated several times by vasopressin

  1982cited by this paper
• Nucleotide sequence of cloned cDNA encoding bovine arginine vasopressin–neurophysin II precursor

  1982cited by this paper
• Changes in tissue sensitivity to vasopressin in hereditary hypothalamic diabetes insipidus

  1981cited by this paper
• A comparison of plasma vasopressin measurements with a standard indirect test in the differential diagnosis of polyuria.

  1981cited by this paper
• Vasopressin secretion in primary polydipsia and cranial diabetes insipidus.

  1981cited by this paper
• A new extraction of arginine vasopressin from blood: The use of octadecasilyl-silica

  1980cited by this paper
• Plasma Vasopressin Response to Hypertonic Saline Infusion to Assess Posterior Pituitary Function 1

  1980cited by this paper
• Vasopressin function in the syndrome of inappropriate antidiuresis.

  1980cited by this paper
• Urinary concentrating ability during dehydration in the absence of vasopressin.

  1979cited by this paper
• The regulation of vasopressin function in health and disease.

  1976cited by this paper
• Distribution, blood transport, and degradation of antidiuretic hormone in man.

  1976cited by this paper
• Identification of the vasopressin producing and of the oxytocin producing neurons in the hypothalamic magnocellular neurosecretory system of the rat

  1975cited by this paper
• Development and clinical application of a new method for the radioimmunoassay of arginine vasopressin in human plasma.

  1973cited by this paper
• Radioimmunoassay of arginine vasopressin in human plasma.

  1973cited by this paper
• Compulsive water drinking.

  1973cited by this paper
• Recognition of partial defects in antidiuretic hormone secretion.

  1970cited by this paper
• Impaired urinary concentration after vasopressin and its gradual correction in hypothalamic diabetes insipidus.

  1968cited by this paper
• Impaired Urinary Concentration after Vasopressin and Its Gradual Correction in Hypothalamic Diabetes Insipidus

  1968cited by this paper
• THE EFFECT OF VARIOUS STATES OF HYDRATION AND THE PLASMA CONCENTRATION ON THE TURNOVER OF ANTIDIURETIC HORMONE IN MAMMALS.

  1964cited by this paper
• A water deprivation test for the differential diagnosis of polyuria.

  1963cited by this paper
• Differential diagnosis between diabetes insipidus and compulsive polydipsia.

  1961cited by this paper
• Compulsive water drinking.

  1959cited by this paper
• Production of hypertonic urine in the absence of pituitary antidiuretic hormone.

  1957cited by this paper
• The use of hypertonic saline infusions in the differential diagnosis of diabetes insipidus and psychogenic polydipsia.

  1947cited by this paper
• The use of hypertonic saline infusions in the differential diagnosis of diabetes insipidus and psychogenic polydipsia.

  1947cited by this paper

• Hyponatremia: Pathophysiology of different etiologies.

  2026cites this paper
• The role of copeptin in stress response: from mechanism to clinical application

  2026cites this paper
• Assessing the Role of Delta Copeptin in the Evaluation of SIAD and CSW.

  2026cites this paper
• Beyond Biomarkers: Blending Copeptin and Clinical Cues to Distinguish Central Diabetes Insipidus from Primary Polydipsia in Children

  2025cites this paper
• Copeptin as a Marker for Vasopressin Dysregulation and Diagnosis.

  2025cites this paper
• Development and Application in Stroke of an Aldehyde nanoparticle-based Amplified Luminescent Proximity Homogeneous Assay for Rapid Quantitative Measurement of Serum Copeptin

  2025cites this paper
• The ADHventures of Asterix and Copeptin: The Hyponatraemia Challenge.

  2025cites this paper
• A novel immunoprecipitation-based targeted liquid chromatography-tandem mass spectrometry analysis for accurate determination for copeptin in human serum

  2025cites this paper
• Comparative Diagnostic Performance of Copeptin After Hypertonic Saline Infusion Versus Water Deprivation Test in Pediatric Patients with Polyuria–Polydipsia Syndrome

  2025cites this paper
• Genetic Factors in Preeclamptic Egyptian Women: Relation with Arginine Vasopressin; A Case-Control Study

  2025cites this paper
• Arginine vasopressin and copeptin: comparative review and perspective in veterinary medicine

  2025cites this paper
• Hormonal and Osmoregulatory Responses in Intraoperative High-Volume Diuresis During Off-Pump Coronary Artery Bypass Grafting: An Exploratory Cohort Study

  2025influential citation
• Diagnosis and treatment of hypernatremia.

  2025cites this paper
• Apelin levels in patients with polyuria-polydipsia syndrome upon copeptin stimulation tests.

  2024cites this paper
• Diagnostic Utility of Copeptin in Pediatric Patients with Polyuria-Polydipsia Syndrome: A Systematic Review and Meta-Analysis

  2024cites this paper
• Hydration Considerations to Improve the Physical Performance and Health of Firefighters

  2024cites this paper
• A New Biomarker Copeptin in Determining Disease Severity in COVID-19

  2024cites this paper
• Biomarkers of Kidney Disease Progression in ADPKD

  2024cites this paper
• Copeptin's role in traumatic brain injury: The promising quest for a new biomarker.

  2024cites this paper
• Nonspecific stress biomarkers for mortality prediction in older emergency department patients presenting with falls: a prospective multicenter observational study

  2024cites this paper
• Anterior and Posterior Pituitary Function in Patients with Sheehan Syndrome – Combining the use of Insulin Tolerance Test and Copeptin Assay

  2024cites this paper
• Apelin and Copeptin Levels in Patients With Chronic SIAD Treated With Empagliflozin

  2024cites this paper
• Case report: Secondary failure to tolvaptan in a patient with SCLC and paraneoplastic SIADH

  2024cites this paper
• Unveiling stress markers: A systematic review investigating psychological stress biomarkers.

  2024cites this paper
• The 3% hypertonic saline infusion test for the differential diagnosis of diabetes insipidus and primary polydipsia: assessment of diagnostic accuracy

  2024cites this paper
• Role of Copeptin in Predicting Postoperative Hyponatremia and Hypernatremia in Patients Undergoing Endoscopic Pituitary Adenoma Surgery

  2024cites this paper
• Understanding long COVID myocarditis: A comprehensive review.

  2024cites this paper
• Food intake, plasma copeptin and cardiovascular risk in patients with type 2 diabetes: A cross-sectional analysis.

  2024cites this paper
• Long-term health outcomes associated with hydration status

  2024cites this paper
• The diagnostic performance of copeptin in clinical practice: A prospective study

  2024cites this paper
• Paediatric perspectives in the diagnosis of polyuria‐polydipsia syndrome

  2024cites this paper
• NECUKRINIS DIABETAS INTENSYVIOSIOS TERAPIJOS SKYRIUJE

  2023cites this paper
• Copeptin: Up-to-date diagnostic and prognostic role highlight.

  2023cites this paper
• Copeptin in autosomal dominant polycystic kidney disease: real-world experiences from a large prospective cohort study

  2023cites this paper
• Potential Biomarkers of Impulsivity in Mild Traumatic Brain Injury: A Pilot Study.

  2023cites this paper
• Syndrome of Inappropriate Antidiuresis: From Pathophysiology to Management

  2023cites this paper
• Copeptin and the prognosis of patients with coronary artery disease: a meta-analysis

  2023cites this paper
• Dissociation of sodium-chloride cotransporter expression and blood pressure during chronic high dietary potassium supplementation

  2023cites this paper
• New developments and concepts in the diagnosis and management of diabetes insipidus (AVP‐deficiency and resistance)

  2023cites this paper
• The diagnostic role of arginine-stimulated copeptin in the differential diagnosis of polyuria-polydipsia syndrome (PPS) in pediatric age

  2023cites this paper
• Copeptin: a novel prognostic biomarker in trauma: a review article

  2023cites this paper
• Test diagnostici per il diabete insipido: un aggiornamento

  2023cites this paper
• Establishment and Clinical Application in Stroke of a Serum Copeptin Time-Resolved Fluorescence Immunoassay

  2023cites this paper
• Early Postoperative Serum Sodium Level and Urine Output Volume Profile after Endoscopic Endonasal Transsphenoidal Surgery in Macroadenoma Pituitary Tumor

  2023cites this paper
• Exogenous ketosis suppresses diuresis and atrial natriuretic peptide during exercise.

  2022cites this paper
• Approach to the Patient: Hyponatremia and the Syndrome of Inappropriate Antidiuresis (SIAD).

  2022cites this paper
• High salt intake activates the hypothalamic–pituitary–adrenal axis, amplifies the stress response, and alters tissue glucocorticoid exposure in mice

  2022cites this paper
• Arginine Vasopressin, Synaptic Plasticity, and Brain Networks

  2022cites this paper
• Assessment of the state and relationship of vasopressor and renin-angiotensin systems in patients with localized kidney cancer on the background of arterial hypertension

  2022cites this paper
• Nephrogenic diabetes insipidus: a comprehensive overview

  2022cites this paper
• Assessment of the state and relationship of vasopressor and renin-angiotensin systems in patients with localized kidney cancer on the background of arterial hypertension

  2022cites this paper
• Serum Copeptin and Renalase in Correlation to Left Ventricular Hypertrophy in Hemodialysis Patients

  2022cites this paper
• Approach To The Pediatric Patient: Central Diabetes Insipidus.

  2022cites this paper
• Evaluation and management of hypernatremia in adults: clinical perspectives

  2022cites this paper
• Disorders of Salt and Water Balance After Pituitary Surgery

  2022cites this paper
• Diabetes insipidus: A rare endocrine complication of immune check point inhibitors: A case report and literature review

  2022cites this paper
• Study The Role of Co-Peptin versus Vascular Cellular Adhesion Molecules (VCAM-1) in Cirrhotic Patients with Hepatorenal Syndrome - Acute Kidney Injury

  2022cites this paper
• Association between Copeptin and Metabolic Syndrome: A Systematic Review

  2022cites this paper
• The role of copeptin in kidney disease

  2022cites this paper
• Utility of cardiac bioenzymes in predicting cardiovascular outcomes in SARS-CoV-2

  2022cites this paper
• Mechanistic insights into the primary and secondary alterations of renal ion and water transport in the distal nephron

  2022cites this paper
• Adult neurogenesis of the median eminence contributes to structural reconstruction and recovery of body fluid metabolism in hypothalamic self-repair after pituitary stalk lesion

  2022cites this paper
• Diagnosis and Management of Central Diabetes Insipidus in Adults.

  2022cites this paper
• Diabetes Insipidus: A Pragmatic Approach to Management

  2021cites this paper
• Copeptin is increased by nausea and vomiting during hypertonic saline infusion in healthy individuals

  2021cites this paper
• Neural basis for regulation of vasopressin secretion by anticipated disturbances in osmolality

  2021cites this paper
• Efficacy of copeptin in distinguishing COVID‐19 pneumonia from community‐acquired pneumonia

  2021cites this paper
• The Effects of Zinc Sulfate Supplementation on Serum Copeptin, C-Reactive Protein and Metabolic Markers in Zinc-Deficient Diabetic Patients on Hemodialysis: A Randomized, Double-Blind, Placebo-Controlled Trial

  2021cites this paper
• Diagnosis and management of diabetes insipidus for the internist: an update

  2021cites this paper
• Diabetes Insipidus: Pathogenesis, Diagnosis, and Clinical Management

  2021cites this paper
• Disorders of the Posterior Pituitary

  2021cites this paper
• Increased angiotensin II formation in the brain modulates cardiovascular homeostasis and erythropoiesis.

  2021cites this paper
• Management of Diabetes Insipidus following Surgery for Pituitary and Suprasellar Tumours

  2021influential citation
• Synchronous pituitary and pineal gland lesions presenting with panhypopituitarism in a patient with widespread colorectal cancer: a case report

  2021cites this paper
• Role of copeptin in the diagnosis of traumatic neuroendocrine dysfunction.

  2021cites this paper
• Association between copeptin levels and treatment responses to hypertonic saline infusion in patients with symptomatic hyponatremia: a prospective cohort study

  2021cites this paper
• Nucleobindin-derived Nesfatin-1 and nesfatin-1-like peptide stimulate pro-opiomelanocortin synthesis in murine AtT-20 corticotrophs through the cAMP/PKA/CREB signaling pathway.

  2021cites this paper
• Risk assessment of sepsis through measurement of proAVP (copeptin): a secondary analysis of the TRIAGE study

  2021influential citation
• Evaluation of copeptin and psychological stress among healthcare providers during COVID-19 pandemic

  2021cites this paper
• Development of a sensitive liquid chromatography-tandem mass spectrometry method for quantification of human plasma arginine vasopressin.

  2021cites this paper
• A novel role of copeptin as a biomarker for the prediction of treatment response in hyponatremia

  2021cites this paper
• Copeptin: a potential blood biomarker for acute ischemic stroke

  2021cites this paper
• Can copeptin predict the severity of coronavirus disease 2019 infection?

  2021cites this paper
• Copeptin and Stress

  2021cites this paper
• Reliability of Biomarkers of Physiological Stress at Rest and Post-exertional Heat Stress

  2021cites this paper
• The effects of zinc sulfate supplementation on serum copeptin, c­reactive protein and metabolic markers in zinc­deficient diabetic patients on hemodialysis: a randomized, double­ blind, placebo­controlled trial

  2021cites this paper
• Pharmacodynamic Evaluation: Endocrinology

  2020cites this paper
• Association between serum copeptin levels and preeclampsia risk: A meta-analysis.

  2020cites this paper
• Copeptin-based diagnosis of diabetes insipidus.

  2020cites this paper
• Low hydration status may be associated with insulin resistance and fat distribution: analysis of the Korea National Health and Nutrition Examination Survey (KNHANES) 2008–2010

  2020cites this paper
• Copeptin is independently associated with vascular calcification in chronic kidney disease stage 5

  2020cites this paper
• Prognostic relevance of elevated plasma osmolality on admission in acute decompensated heart failure with preserved ejection fraction: insights from PURSUIT-HFpEF registry

  2020cites this paper
• Diabetes Insipidus: New Concepts for Diagnosis

  2020cites this paper
• Effects of alcohol consumption on copeptin levels and sodium-water homeostasis.

  2020cites this paper
• Diabetes insipidus complicating apoplexy during pregnancy: the potential use of copeptin

  2020cites this paper
• Expression of Stress-Mediating Genes is Increased in Term Placentas of Women with Chronic Self-Perceived Anxiety and Depression

  2020cites this paper
• Distribution of plasma copeptin levels and influence of obesity in children and adolescents

  2020cites this paper
• Copeptin – Stellenwert in der Diagnostik des Polyurie-Polydipsie-Syndroms

  2020cites this paper
• Arginine-vasopressin mediates counter-regulatory glucagon release and is diminished in type 1 diabetes

  2020cites this paper
• Copeptin response to hypoglycemic stress is linked to prolactin activation in children

  2020cites this paper