Studies on the control of gene expression of the carcinoembryonic antigen family in human tissue.

No abstract is available for this paper.

• Publication year

  1989

• Venue

  Cancer Research

• Publication date

  1989-02-15

• Fields of study

  Biology, Medicine

• Identifiers
  PMID 2912558
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The carcinoembryonic antigen gene family: structure, expression and evolution.

  1988cited by this paper
• Primary structure of nonspecific crossreacting antigen (NCA), a member of carcinoembryonic antigen (CEA) gene family, deduced from cDNA sequence.

  1988cited by this paper
• DNA methylation and gene activity.

  1988cited by this paper
• Transcription of genes of the carcinoembryonic antigen family in malignant and nonmalignant human tissues.

  1988cited by this paper
• Characterization of a cDNA clone for the nonspecific cross-reacting antigen (NCA) and a comparison of NCA and carcinoembryonic antigen.

  1988cited by this paper
• Chromosomal localization of the carcinoembryonic antigen gene family and differential expression in various tumors.

  1988cited by this paper
• Primary structure of human carcinoembryonic antigen (CEA) deduced from cDNA sequence.

  1987cited by this paper
• Carcinoembryonic antigen family: expression in a mouse L-cell transfectant and characterization of a partial cDNA in bacteriophage lambda gt11.

  1987cited by this paper
• Isolation and characterization of cDNA clones encoding the human carcinoembryonic antigen reveal a highly conserved repeating structure.

  1987cited by this paper
• Isolation and characterization of full-length functional cDNA clones for human carcinoembryonic antigen

  1987influential reference
• A year in the life of the immunoglobulin superfamily.

  1987cited by this paper
• Insertion mutagenesis to increase secondary structure within the 5' noncoding region of a eukaryotic mRNA reduces translational efficiency.

  1985cited by this paper
• CEA-related antigens: molecular biology and clinical significance.

  1985cited by this paper
• DNA methylation and gene activity.

  1983cited by this paper
• A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity.

  1983cited by this paper
• Plasma CEA in the post-surgical monitoring of colorectal carcinoma.

  1982cited by this paper
• Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease.

  1979cited by this paper
• Isolation and characterization of carcinoembryonic antigen (CEA) extracted from normal human colon mucosa.

  1977cited by this paper
• Carcinoembryonic antigenic activity of tissue extracts: A quantitative study of malignant and benign neoplasms, cirrhotic liver, normal adult and fetal organs

  1973cited by this paper
• Demonstration of tumor associated antigen in normal colon and lung

  1972cited by this paper
• The radioimmunoassay of circulating carcinoembryonic antigen of the human digestive system.

  1969cited by this paper
• DEMONSTRATION OF TUMOR-SPECIFIC ANTIGENS IN HUMAN COLONIC CARCINOMATA BY IMMUNOLOGICAL TOLERANCE AND ABSORPTION TECHNIQUES

  1965cited by this paper

• Pleural fluid biomarkers for the diagnosis and management of malignant pleural effusions: a clinical review.

  2025cites this paper
• Novel Electrochemical Biosensors for Detecting Specific Colorectal Cancer Biomarkers, Delving Into Advancements in Early Detection and Personalized Treatment Strategies

  2024cites this paper
• Targeting CEACAM5-positive solid tumors using NILK-2401, a novel CEACAM5xCD47 κλ bispecific antibody

  2024cites this paper
• Prognostic value of the postoperative carcinoembryonic antigen level in colorectal cancer: A meta-analysis.

  2024cites this paper
• Development and characterization of NILK-2301, a novel CEACAM5xCD3 κλ bispecific antibody for immunotherapy of CEACAM5-expressing cancers

  2023cites this paper
• Prognostic Value of Carcinoembryonic Antigen Changes Before and After Operation for Esophageal Squamous Cell Carcinoma

  2022cites this paper
• Role of Serum Carcinoembryonic Antigen in Predicting Recurrent Disease following Curative Resection of Rectal Cancer

  2022cites this paper
• A multimer-based SERS aptasensor for highly sensitive and homogeneous assay of carcinoembryonic antigens.

  2021cites this paper
• Near infrared photoimmunotherapy of cancer; possible clinical applications

  2021cites this paper
• The role of carcinoembryonic antigen as an assessment tool for predicting disease severity among patients with colorectal cancer in resource-poor setting of Kwazulu-Natal, South Africa

  2021cites this paper
• Biosensing Near the Exceptional Point Based on Resonant Optical Tunneling Effect

  2021cites this paper
• Predicting the Survival Probability of Neuroendocrine Tumor Populations: Developing and Evaluating a New Predictive Nomogram

  2021cites this paper
• p38γ Activation and BGP (Biliary Glycoprotein) Induction in Primates at Risk for Inflammatory Bowel Disease and Colorectal Cancer—A Comparative Study with Humans

  2020cites this paper
• Immunotherapy of colorectal cancer: Challenges for therapeutic efficacy.

  2019cites this paper
• CMV enhancer may not be suitable for tissue-specific enhancement of promoters in cancer gene therapy

  2019cites this paper
• The Role of Carcinoembryonic Antigen (CEA) Testing in Primary Care-Does It Exist?

  2019cites this paper
• Fluorescent‐guided surgery for sentinel lymph node detection in gastric cancer and carcinoembryonic antigen targeted fluorescent‐guided surgery in colorectal and pancreatic cancer

  2018cites this paper
• Glycan analysis of colorectal cancer samples reveals stage-dependent changes in CEA glycosylation patterns

  2018cites this paper
• Recent Advances in the Clinical Development of Immune Checkpoint Blockade Therapy for Mismatch Repair Proficient (pMMR)/non‐MSI‐H Metastatic Colorectal Cancer

  2018cites this paper
• The role of tissue and serum carcinoembryonic antigen in stages I to III of colorectal cancer—A retrospective cohort study

  2018cites this paper
• Comparing the effects of different cell death programs in tumor progression and immunotherapy

  2018cites this paper
• The challenges of solid tumor for designer CAR-T therapies: a 25-year perspective

  2017cites this paper
• Evaluation of 99mTc‐resveratrol as a colon cancer targeting probe

  2017cites this paper
• The challenges of solid tumor for designer CAR-T therapies: a 25-year perspective

  2017cites this paper
• Development of solid phase immunoradiometric assay for determination of carcinoembryonic antigen as a tumor marker

  2016cites this paper
• Carcinoembryonic Antigen Expression and Resistance to Radiation and 5-Fluorouracil-Induced Apoptosis and Autophagy

  2016cites this paper
• Relation between Carcinoembryonic Antigen Levels in Colon Cancer Tissue and Serum Carcinoembryonic Antigen Levels at Initial Surgery and Recurrence

  2016cites this paper
• Matrix metalloproteinase 9 -1562C/T polymorphism increased protein levels in patients with colorectal cancer in a sample from southeastern Brazil.

  2016cites this paper
• Combating (pre) malignant pancreatic disease : High time for molecular markers

  2015cites this paper
• Clinical application of serum tumor abnormal protein from patients with gastric cancer.

  2015cites this paper
• Alcohol, carcinoembryonic antigen processing and colorectal liver metastases.

  2015cites this paper
• RESEARCH ARTICLE ROLE OF IL10,TNF IN IRAQI PATIENTS WITH COLON CANCER

  2014cites this paper
• Non-coding RNAs and Cancer

  2014cites this paper
• Clinical application and prognostic assessment of serum Tumor Associated Material (TAM) from esophageal cancer patients.

  2014cites this paper
• Antibody-based imaging of prostate cancer

  2014cites this paper
• Mirnas as cancer biomarkers

  2014cites this paper
• Intra-abdominal desmoid tumor mimicking gastric cancer recurrence: a case report

  2014cites this paper
• ROLE OF IL10,TNF IN IRAQI PATIENTS WITH COLON CANCER

  2014cites this paper
• Functional DNA Aptamers as Biotherapeutic Molecules

  2014cites this paper
• Diagnostic Value of Carcinoembryonic Antigen and C-reactive Protein Levels in the Discrimination Between Malignant Pleural Effusion and Parapneumonic Effusion

  2013cites this paper
• Relationship among circulating tumor cells, CEA and overall survival in patients with metastatic colorectal cancer.

  2013cites this paper
• Diagnostic precision of carcinoembryonic antigen level in esophagealcarcinoma.

  2013cites this paper
• Clinical applications of molecular profiling in colorectal cancer: Review of the literature

  2013cites this paper
• Anti-carcinoembryonic Antigen Single-chain Variable Fragment Antibody Variants Bind Mouse and Human Neonatal Fc Receptor with Different Affinities That Reveal Distinct Cross-species Differences in Serum Half-life*

  2012cites this paper
• Comparison of serum tumor associated material (TAM) with conventional biomarkers in cancer patients.

  2012cites this paper
• The Relation Between Serum CEA Response and the CTscan Finding After Neoadjuvant Therapy in Rectal Cancer Patients

  2012cites this paper
• Diagnostic value of interleukin 21 and carcinoembryonic antigen levels in malignant pleural effusions.

  2012cites this paper
• Diagnostic value of interleukin 22 and carcinoembryonic antigen in tuberculous and malignant pleural effusions.

  2011cites this paper
• New Approach to Diagnosis and Prognosis

  2011cites this paper
• HERG1 gene expression as a specific tumor marker in colorectal tissues.

  2010cites this paper
• Delivering cargoes into cancer cells using DNA aptamers targeting internalized surface portals.

  2010cites this paper
• Comparison of carcinoembryonic antigen prognostic value in serum and tumour tissue of patients with colorectal cancer

  2009cites this paper
• Intrarectal Vaccination with Recombinant Vaccinia Virus Expressing Carcinoembronic Antigen Induces Mucosal and Systemic Immunity and Prevents Progression of Colorectal Cancer1

  2008cites this paper
• Second-Generation Anti–Carcinoembryonic Antigen Designer T Cells Resist Activation-Induced Cell Death, Proliferate on Tumor Contact, Secrete Cytokines, and Exhibit Superior Antitumor Activity In vivo: A Preclinical Evaluation

  2008cites this paper
• Diagnostic value of carcinoembryonic antigen in malignant pleural effusion: A meta‐analysis

  2008cites this paper
• Role of endogenous TGF-beta in glucocorticoid-induced lung type II cell differentiation.

  2007cites this paper
• Immunization with Mimotopes Prevents Growth of Carcinoembryonic Antigen–Positive Tumors in BALB/c Mice

  2007cites this paper
• Increased colon tumor susceptibility in azoxymethane treated CEABAC transgenic mice.

  2006cites this paper
• Differential Regulation of Carcinoembryonic Antigen and Biliary Glycoprotein by 7-Interferon 1

  2006cites this paper
• Simplex Virus Thymidine Kinase Gene Lung Cancer Cells by Cell Type-specific Expression of Herpes Gene Therapy for Carcinoembryonic Antigen-producing Human Updated

  2006cites this paper
• Genetic and Pathologic Changes associated with Lymphovascular Invasion of Colorectal Adenocarcinoma

  2005cites this paper
• Retroviral targeting to tumour antigens

  2004cites this paper
• Design and cancer-targeting potential of antibody-based molecules directed against carcinoembryonic antigen.

  2004cites this paper
• Metastatic potential of human colon cancer cell lines: relationship to cellular differentiation and carcinoembryonic antigen production

  2004cites this paper
• Carcinoembryonic antigen directed herpes viral oncolysis improves selectivity and activity in colorectal cancer.

  2004cites this paper
• Coexpression of carcinoembryonic antigen and e-cadherin in colorectal adenocarcinoma with liver metastasis

  2003cites this paper
• Deregulated expression of the human tumor marker CEA and CEA family member CEACAM6 disrupts tissue architecture and blocks colonocyte differentiation.

  2002cites this paper
• Carcinoembryonic antigen as a marker for colorectal cancer: is it clinically useful?

  2001cites this paper
• The GPI-anchor and protein sorting

  2001cites this paper
• The Specificity for the Differentiation Blocking Activity of Carcinoembryonic Antigen Resides in Its Glycophosphatidyl-Inositol Anchor

  2000influential citation
• Bypassing immunization: optimized design of "designer T cells" against carcinoembryonic antigen (CEA)-expressing tumors, and lack of suppression by soluble CEA.

  1999cites this paper
• Factors Influencing Tumor-Selective Localization of Antibody Conjugates

  1999cites this paper
• Humanisation and characterisation of PR1A3, a monoclonal antibody specific for cell-bound carcinoembryonic antigen

  1999cites this paper
• The molecular genetics of colonic cancer.

  1998cites this paper
• Expression of four CEA family antigens (CEA, NCA, BGP and CGM2) in normal and cancerous gastric epithelial cells: Up‐regulation of BGP and CGM2 in carcinomas

  1998cites this paper
• Comparison of carcinoembryonic antigen promoter regions isolated from human colorectal carcinoma and normal adjacent mucosa to induce strong tumor‐selective gene expression

  1998cites this paper
• A single-chain immunotoxin against carcinoembryonic antigen that suppresses growth of colorectal carcinoma cells.

  1998cites this paper
• Carcinoma Cells at Deeply Infiltrated Sites: Role in Development of Metastases in Patients with Advanced Colorectal Adenocarcinomas

  1997cites this paper
• Carcinoembryonic Antigen, a Human Tumor Marker, Cooperates with Myc and Bcl-2 in Cellular Transformation

  1997cites this paper
• Induction of nonspecific cross-reacting antigen mRNA by interferon-γ and anti-fibronectin receptor antibody in colon cancer cells

  1997cites this paper
• The 3' untranslated region of the carcinoembryonic antigen gene plays a minimal role in the regulation of gene expression.

  1997cites this paper
• Neoplasms with sweat gland differentiation express various glycoproteins of the carcinoembryonic antigen (CEA) family

  1996cites this paper
• Radical differences in functions of closely related members of the human carcinoembryonic antigen gene family.

  1996cites this paper
• Cell adhesion molecules 1: immunoglobulin superfamily.

  1995cites this paper
• The rat liver ecto-ATPase/C-CAM cDNA detects induction of carcinoembryonic antigen but not the mercurial-insensitive ecto-ATPase in human hepatoma Li-7A cells treated by epidermal growth factor and cholera toxin.

  1995cites this paper
• Significance of cea and CA242 in the diagnosis of colorectal carcinoma

  1995cites this paper
• Transcriptional Regulation of the Carcinoembryonic Antigen Gene

  1995cites this paper
• Characterization and transcriptional activity of the mouse biliary glycoprotein 1 gene, a carcinoembryonic antigen-related gene.

  1995cites this paper
• The use of Epstein-Barr virus-transformed B lymphocyte cell lines in a peptide-reconstitution assay: identification of CEA-related HLA-A*0301-restricted potential cytotoxic T-lymphocyte epitopes.

  1995cites this paper
• Opposite functions for two classes of genes of the human carcinoembryonic antigen family.

  1995cites this paper
• Effect of cigarette smoke on the mRNA and protein expression of carcinoembryonic antigen (CEA), a possible chemoattractant for neutrophils in human bronchioloalveolar tissues.

  1995cites this paper
• Adhesion molecules, cellular differentiation, and colonic crypt architecture.

  1994cites this paper
• CGM2, a member of the carcinoembryonic antigen gene family is down-regulated in colorectal carcinomas.

  1994cites this paper
• Biliary glycoprotein mRNA expression is increased in primary lung cancer, especially in squamous cell carcinoma.

  1994cites this paper
• Gene therapy for carcinoembryonic antigen-producing human lung cancer cells by cell type-specific expression of herpes simplex virus thymidine kinase gene.

  1994cites this paper
• Cell adhesion molecules. 1: immunoglobulin superfamily.

  1994cites this paper
• Homophilic adhesion between Ig superfamily carcinoembryonic antigen molecules involves double reciprocal bonds

  1993cites this paper
• Differential regulation of carcinoembryonic antigen and biliary glycoprotein by gamma-interferon.

  1993cites this paper
• Human carcinoembryonic antigen, an intercellular adhesion molecule, blocks fusion and differentiation of rat myoblasts

  1993cites this paper
• Specificity of anti-carcinoembryonic antigen monoclonal antibodies and their effects on CEA-mediated adhesion.

  1993cites this paper