Megalin is an endocytic receptor for insulin.

No abstract is available for this paper.

• Publication year

  1998

• Venue

  Journal of the American Society of Nephrology

• Publication date

  1998-10-01

• Fields of study

  Biology, Medicine

• Identifiers
  PMID 9773776
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Pathogenic antibodies inhibit the binding of apolipoproteins to megalin/gp330 in passive Heymann nephritis.

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  1997cited by this paper
• Endocytic trafficking of megalin/RAP complexes: dissociation of the complexes in late endosomes.

  1997cited by this paper
• Tissue Distribution of Human gp330/Megalin, a Putative Ca2+-sensing Protein

  1997cited by this paper
• Hormone, growth factor, and vitamin handling by proximal tubule cells.

  1997cited by this paper
• Megalin/gp330 mediates uptake of albumin in renal proximal tubule.

  1996cited by this paper
• Megalin-mediated endocytosis of transcobalamin-vitamin-B12 complexes suggests a role of the receptor in vitamin-B12 homeostasis.

  1996cited by this paper
• Defective forebrain development in mice lacking gp330/megalin.

  1996cited by this paper
• Processing of 125I-insulin by polarized cultured kidney cells.

  1996cited by this paper
• Evidence that epithelial glycoprotein 330/megalin mediates uptake of polybasic drugs.

  1995cited by this paper
• The expression of megalin (gp330) and LRP diverges during F9 cell differentiation.

  1995cited by this paper
• The Heymann nephritis antigenic complex: megalin (gp330) and RAP.

  1995cited by this paper
• An overview of the structure and function of glycoprotein 330, a receptor related to the alpha 2-macroglobulin receptor.

  1994cited by this paper
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  1994cited by this paper
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  1994cited by this paper
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  1994cited by this paper
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  1994cited by this paper
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  1994cited by this paper
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  1994cited by this paper
• An Overview of the Structure and Function of Glycoprotein 330, a Receptor Related to the α2‐Macroglobulin Receptor a

  1994cited by this paper
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• Immunocytochemical and biochemical characterization of the Heymann nephritis antigenic complex in rat L2 yolk sac cells.

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  1993cited by this paper
• Endocytosis in proximal tubule cells involves a two-phase membrane-recycling pathway.

  1993cited by this paper
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  1993cited by this paper
• Sorting and recycling efficiency of apical insulin binding sites during endocytosis in proximal tubule cells.

  1993cited by this paper
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  1992cited by this paper
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  1992cited by this paper
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  1988cited by this paper
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  1988cited by this paper
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  1986cited by this paper
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  1986cited by this paper
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  1985cited by this paper
• Interaction of insulin with the renal proximal tubular cell.

  1985cited by this paper
• Insulin-stimulated phosphorylation and insulin binding in canine renal basolateral membranes.

  1984cited by this paper
• Presence of an extensive clathrin coat on the apical plasmalemma of the rat kidney proximal tubule cell

  1984cited by this paper
• Endocytosis in kidney proximal tubule cells and cultured fibroblasts: a review of the structural aspects of membrane recycling between the plasma membrane and endocytic vacuoles.

  1984cited by this paper
• Microdomains of distinctive glycoprotein composition in the kidney proximal tubule brush border

  1984cited by this paper
• Insulin binding sites in various segments of the rabbit nephron.

  1983cited by this paper
• Immunocytochemical localization of the Heymann nephritis antigen (GP330) in glomerular epithelial cells of normal Lewis rats

  1983cited by this paper
• Renal tubular uptake of protein: effect of molecular charge.

  1983cited by this paper
• The pathogenic antigen of Heymann nephritis is a membrane glycoprotein of the renal proximal tubule brush border.

  1982cited by this paper
• Binding and Degradation of Insulin by Isolated Renal Brush Border Membranes

  1982cited by this paper
• Renal tubular processing of small peptide hormones.

  1982cited by this paper
• Kinetics, competition, and selectivity of tubular absorption of proteins.

  1982cited by this paper
• Insulin Binding and Degradation by Kidney Cell Membranes of Streptozotocin-Diabetic Rats

  1982cited by this paper
• Effect of molecular charge on endocytic uptake of ferritin in renal proximal tubule cells.

  1981cited by this paper
• Metabolic Characteristics of Renal Insulin Uptake

  1981cited by this paper
• Inhibition of renal accumulation of lysozyme (basic low molecular weight protein) by basic proteins and other basic substances

  1981cited by this paper
• Radioautographic visualization of in vivo insulin binding to the exocrine pancreas.

  1980cited by this paper
• Polypeptide hormone receptors in vivo: demonstration of insulin binding to adrenal gland and gastrointestinal epithelium by quantitative radioautography.

  1980cited by this paper
• Binding and uptake of 125I-insulin into rat liver hepatocytes and endothelium. An in vivo radioautographic study

  1979cited by this paper
• Renal filtration, transport, and metabolism of low-molecular-weight proteins: a review.

  1979cited by this paper
• Quantitative studies of protein uptake in microperfused renal proximal tubules.

  1977cited by this paper
• Insulin uptake in the renal proximal tubule

  1973cited by this paper
• Insulin uptake in the renal proximal tubule.

  1973cited by this paper
• Glomerular filtration and proximal tubular absorption of insulin 125 I.

  1972cited by this paper
• Metabolism of insulin-I 131 and glucagon-I 131 in the kidney of the rat.

  1958cited by this paper

• Tubular proteinuria due to hereditary endocytic receptor disorder of the proximal tubule: Dent disease and chronic benign proteinuria

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