The success of various endometrioma treatments in infertility: A systematic review and meta‐analysis of prospective studies

Endometriosis is seen in 0.5%‐5% of fertile and 25%‐40% of infertile women. To investigate this conflict between gynecologists that ovarian endometriomas should be removed or not before making any decision about pregnancy among infertile women, the authors decided to carry out a systematic review and meta‐analysis to compare the effect of various available therapeutic methods and notice the impact of these options on women's pregnancy rate.

• Publication year

  2019

• Venue

  Reproductive Medicine and Biology

• Publication date

  2019-06-19

• Fields of study

  Medicine

• Identifiers
  DOI 10.1002/rmb2.12286PMID 31607791PMCID 6780037
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The success of various endometrioma treatments in infertility: A systematic review and meta‐analysis of prospective studies

  2019cited by this paper
• Predictors of IVF/ICSI success following treatment of endometriosis as the cause of primary infertility.

  2018cited by this paper
• EndoART: A proposed randomized controlled trial on endometriomas in assisted reproductive technologies, comparing the effect of no intervention, surgery, and prolonged GnRH downregulation on pregnancy rates

  2018cited by this paper
• Prevalence Rate of Hepatitis B Virus in Pregnancy: Implications From a Systematic Review and Meta-Analysis of Studies Published From 2000 to 2016

  2018cited by this paper
• In Vitro Fertilization Success Rates after Surgically Treated Endometriosis and Effect of Time Interval between Surgery and In Vitro Fertilization.

  2018cited by this paper
• Endometrioma, fertility, and assisted reproductive treatments: connecting the dots

  2018cited by this paper
• Experimental Endometriosis: Review of the Literature Through a Century and the Iranian Experience.

  2018cited by this paper
• Diagnostic accuracy of magnetic resonance imaging, transvaginal, and transrectal ultrasonography in deep infiltrating endometriosis

  2018cited by this paper
• An update on the diagnosis, surgical management, and fertility outcomes for women with endometrioma

  2017cited by this paper
• Surgical outcomes of laparoscopic endometriosis surgery: a 6 year experience

  2017cited by this paper
• Quality Assessment Tool for Observational Cohort and Cross-Sectional Studies

  2017cited by this paper
• Sclerotherapy in the management of ovarian endometrioma: systematic review and meta-analysis.

  2017cited by this paper
• Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015: elaboration and explanation

  2016cited by this paper
• Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015: elaboration and explanation

  2015cited by this paper
• An Update on Surgical versus Expectant Management of Ovarian Endometriomas in Infertile Women

  2015cited by this paper
• The impact of laparoscopic cystectomy on ovarian reserve in patients with unilateral and bilateral endometriomas.

  2014cited by this paper
• ESHRE guideline: management of women with endometriosis.

  2014cited by this paper
• The impact of endometrioma and laparoscopic cystectomy on ovarian reserve and the exploration of related factors assessed by serum anti-Mullerian hormone: a prospective cohort study

  2014cited by this paper
• The distinguishing cellular and molecular features of the endometriotic ovarian cyst: from pathophysiology to the potential endometrioma-mediated damage to the ovary.

  2014cited by this paper
• The effect of surgery for endometrioma on ovarian reserve evaluated by antral follicle count: a systematic review and meta-analysis.

  2014cited by this paper
• Treatment of pelvic pain associated with endometriosis: a committee opinion.

  2014cited by this paper
• Effect of surgery for endometrioma on ovarian function: a different point of view.

  2014cited by this paper
• Laparoscopic Ovarian Cystectomy versus Fenestration/Coagulation or Laser Vaporization for the Treatment of Endometriomas: A Meta-Analysis of Randomized Controlled Trials

  2013cited by this paper
• In women with endometriosis anti-Müllerian hormone levels are decreased only in those with previous endometrioma surgery.

  2012cited by this paper
• The impact of excision of ovarian endometrioma on ovarian reserve: a systematic review and meta-analysis.

  2012cited by this paper
• Elaboration and Explanation ⋆

  2011cited by this paper
• Endometriomas as a possible cause of reduced ovarian reserve in women with endometriosis.

  2011cited by this paper
• Laparoscopic stripping of endometriomas negatively affects ovarian follicular reserve even if performed by experienced surgeons.

  2011cited by this paper
• Recurrence of endometriosis and its control.

  2009cited by this paper
• Oxidative stress impairs oocyte quality and melatonin protects oocytes from free radical damage and improves fertilization rate

  2008cited by this paper
• Excisional surgery versus ablative surgery for ovarian endometriomata.

  2008cited by this paper
• Oxidative stress status in normal ovarian cortex surrounding ovarian endometriosis.

  2008cited by this paper
• A comparison of follicular response of ovaries to ovulation induction after laparoscopic ovarian cystectomy or fenestration and coagulation versus normal ovaries in patients with endometrioma.

  2007cited by this paper
• Postsurgical ovarian failure after laparoscopic excision of bilateral endometriomas.

  2006cited by this paper
• Reactive oxygen species level in follicular fluid--embryo quality marker in IVF?

  2006cited by this paper
• Effect of endometrioma cystectomy on IVF outcome: a prospective randomized study.

  2006cited by this paper
• The Effects of Oxidative Stress on Outcomes of Assisted Reproductive Techniques

  2006cited by this paper
• Excisional surgery versus ablative surgery for ovarian endometriomata.

  2005cited by this paper
• Sclerotherapy with 5% tetracycline is a simple alternative to potentially complex surgical treatment of ovarian endometriomas before in vitro fertilization.

  2004cited by this paper
• A prospective, randomized study comparing laparoscopic ovarian cystectomy versus fenestration and coagulation in patients with endometriomas.

  2004cited by this paper
• Endometriosis and Inflammation in Infertility

  2004cited by this paper
• Aspiration of ovarian endometriomas before intracytoplasmic sperm injection.

  2004cited by this paper
• Management of ovarian endometriomas.

  2002cited by this paper
• Pretreatment for Ovarian Endometrial Cyst before in vitro Fertilization

  2002cited by this paper
• Quantifying heterogeneity in a meta‐analysis

  2002cited by this paper
• Effects of previous ovarian surgery for endometriosis on the outcome of assisted reproduction treatment.

  2002cited by this paper
• Efficacy of ethanol sclerotherapy for ovarian endometriomas

  2001cited by this paper
• Recurrence of ovarian endometrioma after laparoscopic excision.

  1999cited by this paper
• Ovarian cortex surrounding benign neoplasms: a histologic study.

  1993cited by this paper
• Deeply infiltrating pelvic endometriosis: histology and clinical significance.

  1990cited by this paper
• Meta-analysis in clinical trials.

  1986cited by this paper

• A Narrative Review Regarding Implication of Ovarian Endometriomas in Infertility

  2025influential citation
• Ethanol sclerotherapy for management of endometriomas: an overview of systematic reviews

  2025cites this paper
• Relation of Endometrioma and Deep Infiltrating Endometriosis Surgery on Ovarian Reserve: A Large Single-Centre, Cross-Sectional Study

  2025cites this paper
• Matrix Tropism Influences Endometriotic Cell Attachment Patterns

  2025cites this paper
• Effect of endometriosis and adenomyosis on oocyte quality: an evaluation of 205,978 oocytes.

  2025cites this paper
• The Effect of Surgery on Endometriomas on Fertility (2025 Second Edition)

  2025cites this paper
• Endometrioma and Infertility

  2025cites this paper
• Impact of non-medical treatments of endometrioma on pregnancy outcome: a systematic review and meta-analysis.

  2025cites this paper
• Future of Sclerotherapy in the Treatment of Endometriosis: A Narrative Literature Review

  2025cites this paper
• The endometrioma paradox

  2025cites this paper
• Indirect markers of oocyte quality in patients with ovarian endometriosis undergoing IVF/ICSI: a systematic review and meta-analysis.

  2024cites this paper
• Assisted Reproductive Technology Outcomes After Ethanol Sclerotherapy in Poor Responder Patients with Endometriomas: A Before-After Clinical Trial

  2024cites this paper
• Evaluation of Ovarian Reserve and Recurrence Rate After DWLS Diode Laser Ovarian Endometrioma Vaporization (OMAlaser): A Prospective, Single-arm, Multicenter, Clinical Trial.

  2024cites this paper
• Surgical Technique and Fertility Outcomes: A Comprehensive Review of Open and Laparoscopic Cystectomy in Women of Reproductive Age

  2024cites this paper
• Bladder endometriosis: symptoms and pregnancy outcomes.

  2024cites this paper
• Experience of using transvaginal sclerotherapy in the treatment of ovarian endometriomas.

  2024cites this paper
• Endometriosis and In Vitro Fertilization

  2024cites this paper
• Endometrioma surgery: Hit with your best shot (But know when to stop).

  2024cites this paper
• Systematic review and meta-analysis on the effect of adjuvant gonadotropin-releasing hormone agonist (GnRH-a) on pregnancy outcomes in women with endometriosis following conservative surgery

  2024cites this paper
• Controversias en el tratamiento de la endometriosis en la mujer estéril

  2023cites this paper
• Kinderwunschtherapie mit Spendersamen – auf welcher Basis entscheiden wir über Umfang und Konsequenzen der vorausgehenden Diagnostik?

  2023cites this paper
• Endometriose und Kinderwunsch

  2023cites this paper
• Treatment after endometrioma recurrence: a narrative review.

  2023cites this paper
• Endometriosis, Oocyte, and Embryo Quality

  2023cites this paper
• Fertilität bei Endometriose

  2023cites this paper
• Surgical Management of Ovarian Endometrioma: Impact on Ovarian Reserve Parameters and Reproductive Outcomes

  2023cites this paper
• The Efficiency of Sclerotherapy for the Management of Endometrioma: A Systematic Review and Meta-Analysis of Clinical and Fertility Outcomes

  2023cites this paper
• Treatment of endometriomas: Surgical approaches and the impact on ovarian reserve, recurrence, and spontaneous pregnancy.

  2023cites this paper
• Endometrioma and assisted reproductive technology: a review

  2022cites this paper
• Clinical Pregnancy Rate in in-Vitro Fertilization (IVF) among Endometrioma Patients Underwent Cystectomy Laparoscopy

  2022cites this paper
• Endometriosis-associated infertility: From pathophysiology to tailored treatment

  2022cites this paper
• Effect of surgical treatment on fertility in patients with endometrioid cysts

  2022cites this paper
• Comparison of the effect on the ovarian reserve of modern methods of treatment of endometrioid cysts.

  2022cites this paper
• ESHRE guideline: endometriosis

  2022cites this paper
• Laparoscopic stripping versus endometrioma ethanol sclerotherapy in women with endometrioma awaiting IVF: a long-term analysis of ovarian reserve and pregnancy outcome.

  2022cites this paper
• Outcomes of Laparoscopic Partial Cystectomy of Bladder Endometriosis: A Report of 18 Thai Women

  2021cites this paper
• Assisted reproductive technique outcomes in patients with endometrioma undergoing sclerotherapy vs laparoscopic cystectomy: Prospective cross‐sectional study

  2021cites this paper
• Ovarian endometriosis and fertility preservation problem

  2021cites this paper
• The effect of vasopressin injection on ovarian reserve in patients with ovarian endometrioma: a randomized controlled trial.

  2021cites this paper
• Effects of ovarian endometrioma aspiration on in vitro fertilization-intracytoplasmic sperm injection and embryo transfer outcomes: a systematic review and meta-analysis

  2021cites this paper
• Impact of Surgical Management of Endometrioma on AMH Levels and Pregnancy Rates: A Review of Recent Literature

  2021cites this paper
• E cacy of Intrauterine Insemination in Women with Endometrioma-Associated Subfertility: Analysis Using Propensity Score Matching

  2021cites this paper
• Efficacy of intrauterine insemination in women with endometrioma-associated subfertility: analysis using propensity score matching

  2021cites this paper
• Pathophysiological Basis of Endometriosis-Linked Stress Associated with Pain and Infertility: A Conceptual Review

  2020cites this paper
• Endometrial stromal cell inflammatory phenotype during severe ovarian endometriosis as a cause of endometriosis-associated infertility.

  2020cites this paper
• The options for the surgical treatment of endometrioid ovarian cysts in order to preserve the ovarian reserve (literature review)

  2020cites this paper
• Fertility outcome after CO2 laser vaporization versus cystectomy in women with ovarian endometrioma: a comparative study.

  2020cites this paper
• The success of various endometrioma treatments in infertility: A systematic review and meta‐analysis of prospective studies

  2019cites this paper
• SCIENTIFIC DIGEST OF ASSOCIATION OF OBSTETRICIANS AND GYNAECOLOGISTS OF UKRAINE

  year unknowncites this paper
• ESHRE guideline: endometriosis † The members of the Endometriosis Guideline Core Group

  year unknowncites this paper