Protective effect of proanthocyanidins on anoxia-reoxygenation injury of myocardial cells mediated by the PI3K/Akt/GSK-3β pathway and mitochondrial ATP-sensitive potassium channel.

No abstract is available for this paper.

• Publication year

  2014

• Venue

  Molecular Medicine Reports

• Publication date

  2014-10-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.3892/mmr.2014.2459PMID 25109283
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Protective effects elicited by levosimendan against liver ischemia/reperfusion injury in anesthetized rats

  2014cited by this paper
• Long-term streptozotocin-induced diabetes in rats leads to severe damage of brain blood vessels and neurons via enhanced oxidative stress.

  2013cited by this paper
• Temporal trends in percutaneous coronary intervention outcomes among older patients in the United States.

  2013influential reference
• Inhibition of fatty acid synthase suppresses osteosarcoma cell invasion and migration via downregulation of the PI3K/Akt signaling pathway in vitro.

  2013cited by this paper
• Effect of HEMADO on Level of CK-MB and LDH Enzymes after Ischemia/Reperfusion Injury in Isolated Rat Heart.

  2013cited by this paper
• Changes in cardiac mitochondrial aldehyde dehydrogenase 2 activity in relation to oxidative stress and inflammatory injury in diabetic rats.

  2013cited by this paper
• Role of the JAK/STAT signaling pathway in the pathogenesis of acute myocardial infarction in rats and its effect on NF-κB expression.

  2013cited by this paper
• Positive correlation between variants of lipid metabolism-related genes and coronary heart disease

  2013cited by this paper
• Berberine induces selective apoptosis through the AMPK‑mediated mitochondrial/caspase pathway in hepatocellular carcinoma.

  2013cited by this paper
• Oxidative stress, mitochondrial permeability transition pore opening and cell death during hypoxia-reoxygenation in adult cardiomyocytes.

  2012cited by this paper
• Grape seed proanthocyanidin extract alleviates ouabain-induced vascular remodeling through regulation of endothelial function

  2012cited by this paper
• Oxytocin protects cardiomyocytes from apoptosis induced by ischemia-reperfusion in rat heart: role of mitochondrial ATP-dependent potassium channel and permeability transition pore.

  2012cited by this paper
• Diazoxide attenuates ischemia/reperfusion injury via upregulation of heme oxygenase-1 after liver transplantation in rats.

  2012cited by this paper
• Proanthocyanidins: Oligomeric Structures with Unique Biochemical Properties and Great Therapeutic Promise

  2012cited by this paper
• Geranylgeranylacetone protects against myocardial ischemia and reperfusion injury by inhibiting high-mobility group box 1 protein in rats.

  2011cited by this paper
• Methods in cardiomyocyte isolation, culture, and gene transfer.

  2011cited by this paper
• Familial CJD Associated PrP Mutants within Transmembrane Region Induced Ctm-PrP Retention in ER and Triggered Apoptosis by ER Stress in SH-SY5Y Cells

  2011cited by this paper
• Pathogenesis of myocardial ischemia-reperfusion injury and rationale for therapy.

  2010cited by this paper
• Preconditioning with diazoxide prevents reoxygenation-induced rigor-type hypercontracture.

  2010cited by this paper
• Cytosolic prion protein induces apoptosis in human neuronal cell SH-SY5Y via mitochondrial disruption pathway.

  2009cited by this paper
• Atorvastatin and Myocardial Reperfusion Injury: New Pleiotropic Effect Implicating Multiple Prosurvival Signaling

  2005cited by this paper
• Regulation and termination of NADPH oxidase activity

  2005cited by this paper
• Postconditioning Inhibits Mitochondrial Permeability Transition

  2005cited by this paper
• Statins inhibit reoxygenation-induced cardiomyocyte apoptosis: role for glycogen synthase kinase 3beta and transcription factor beta-catenin.

  2004cited by this paper
• Statins inhibit reoxygenation-induced cardiomyocyte apoptosis: role for glycogen synthase kinase 3β and transcription factor β-catenin

  2004cited by this paper
• Minocycline inhibits caspase activation and reactivation, increases the ratio of XIAP to smac/DIABLO, and reduces the mitochondrial leakage of cytochrome C and smac/DIABLO.

  2004cited by this paper
• Antioxidants in myocardial ischemia-reperfusion injury: therapeutic potential and basic mechanisms.

  2003cited by this paper
• Inhibition of myocardial apoptosis reduces infarct size and improves regional contractile dysfunction during reperfusion.

  2003cited by this paper
• Cardioprotective effects of grape seed proanthocyanidin against ischemic reperfusion injury.

  1999cited by this paper
• Culturing of calcium stable adult cardiac myocytes.

  1982cited by this paper
• DNA synthesis in cultured adult cardiocytes.

  1981cited by this paper

• Metabolic-Electrophysiological Coupling in Heart Failure: from Bidirectional Decoupling to Therapeutic Recoupling

  2025cites this paper
• Flavonoids as Modulators of Potassium Channels

  2023cites this paper
• Role of Flavonoids in Modulation of Mitochondria Dynamics during Oxidative Stress.

  2023cites this paper
• Aloe polymeric acemannan inhibits the cytokine storm in mouse pneumonia models by modulating macrophage metabolism.

  2022cites this paper
• Flavonoids as new regulators of mitochondrial potassium channels: contribution to cardioprotection.

  2022cites this paper
• An Emerging Role of Proanthocyanidins on Psoriasis: Evidence from a Psoriasis-Like Mouse Model

  2022influential citation
• Protective effects of natural products against myocardial ischemia/reperfusion: Mitochondria-targeted therapeutics.

  2022cites this paper
• Flavonoids and Mitochondria: Activation of Cytoprotective Pathways?

  2020cites this paper
• Polyphenols isolated from lychee seed inhibit Alzheimer's disease-associated Tau through improving insulin resistance via the IRS-1/PI3K/Akt/GSK-3β pathway.

  2020cites this paper
• Lipid rafts as potential mechanistic targets underlying the pleiotropic actions of polyphenols

  2020cites this paper
• A Novel Chinese Medicine, Xinfeng Capsule, Modulates Proinflammatory Cytokines via Regulating the Toll-Like Receptor 4 (TLR4)/Mitogen-Activated Protein Kinase (MAPK)/Nuclear Kappa B (NF-κB) Signaling Pathway in an Adjuvant Arthritis Rat Model

  2019cites this paper
• Protective effects of Myrica rubra flavonoids against hypoxia/reoxygenation-induced cardiomyocyte injury via the regulation of the PI3K/Akt/GSK3β pathway

  2019cites this paper
• Decoy receptor-3 regulates inflammation and apoptosis via PI3K/AKT signaling pathway in coronary heart disease

  2019cites this paper
• Actinidia chinensis planch polysaccharide protects against hypoxia-induced apoptosis of cardiomyocytes in vitro

  2018cites this paper
• Tonifying qi and Warming yang, a compound traditional Chinese herbal medicine, suppresses AngII-induced cardiac H9c2 cells apoptosis through regulating PI3K/Akt signaling pathway

  2018cites this paper
• Proanthocyanidin B2 attenuates high-glucose-induced neurotoxicity of dorsal root ganglion neurons through the PI3K/Akt signaling pathway

  2018cites this paper
• Drug-containing serum of Xinfeng capsules protect against H9C2 from death by enhancing miRNA-21 and inhibiting toll-like receptor 4/phosphorylated p-38 (p-p38)/p-p65 signaling pathway and proinflammatory cytokines expression

  2018cites this paper
• Isoflurane reduces pain and inhibits apoptosis of myocardial cells through the phosphoinositide 3-kinase/protein kinase B signaling pathway in mice during cardiac surgery

  2018cites this paper
• The Key Roles of GSK-3β in Regulating Mitochondrial Activity

  2017cites this paper
• Clinical value of CagA, c-Met, PI3K and Beclin-1 expressed in gastric cancer and their association with prognosis

  2017cites this paper
• Pharmacological Inhibition of NLRP3 Inflammasome Attenuates Myocardial Ischemia/Reperfusion Injury by Activation of RISK and Mitochondrial Pathways

  2016cites this paper
• Paeoniflorin inhibits human gastric carcinoma cell proliferation through up-regulation of microRNA-124 and suppression of PI3K/Akt and STAT3 signaling.

  2015cites this paper
• Reduction of apoptosis by proanthocyanidin-induced autophagy in the human gastric cancer cell line MGC-803

  2015cites this paper
• Desflurane preconditioning protects human umbilical vein endothelial cells against anoxia/reoxygenation by upregulating NLRP12 and inhibiting non-canonical nuclear factor-κB signaling.

  2015cites this paper