Genetic analyses in asthma: current concepts and future directions.

No abstract is available for this paper.

• Publication year

  2002

• Venue

  American Journal of Pharmacogenomics

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  PMID 12383022
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2000cited by this paper
• Atopy and a mutation in the interleukin-4 receptor gene.

  2000cited by this paper
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• Recent advances in the genetics of allergy and asthma.

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