A Quantitative and Kinetic Fusion Protein-Triggering Assay Can Discern Distinct Steps in the Nipah Virus Membrane Fusion Cascade

No abstract is available for this paper.

• Publication year

  2010

• Venue

  Journal of Virology

• Publication date

  2010-06-02

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1128/JVI.00469-10PMID 20519383PMCID PMC2916531
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• A Novel Receptor-induced Activation Site in the Nipah Virus Attachment Glycoprotein (G) Involved in Triggering the Fusion Glycoprotein (F)*

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• Structures and mechanisms of viral membrane fusion proteins: multiple variations on a common theme.

  2008influential reference
• Structural basis of Nipah and Hendra virus attachment to their cell-surface receptor ephrin-B2

  2008cited by this paper
• Residues in the Stalk Domain of the Hendra Virus G Glycoprotein Modulate Conformational Changes Associated with Receptor Binding

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• Host cell recognition by the henipaviruses: Crystal structures of the Nipah G attachment glycoprotein and its complex with ephrin-B3

  2008cited by this paper
• Paramyxoviruses: different receptors - different mechanisms of fusion.

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• Functional Interaction between Paramyxovirus Fusion and Attachment Proteins*

  2008cited by this paper
• Mutations in the Stalk of the Measles Virus Hemagglutinin Protein Decrease Fusion but Do Not Interfere with Virus-Specific Interaction with the Homologous Fusion Protein

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• Polybasic KKR Motif in the Cytoplasmic Tail of Nipah Virus Fusion Protein Modulates Membrane Fusion by Inside-Out Signaling

  2007influential reference
• Molecular Determinants of Antiviral Potency of Paramyxovirus Entry Inhibitors

  2007cited by this paper
• Structural basis of viral invasion: lessons from paramyxovirus F.

  2007cited by this paper
• Crystal structures of Nipah and Hendra virus fusion core proteins

  2006cited by this paper
• Two Key Residues in EphrinB3 Are Critical for Its Use as an Alternative Receptor for Nipah Virus

  2006influential reference
• Addition of N-Glycans in the Stalk of the Newcastle Disease Virus HN Protein Blocks Its Interaction with the F Protein and Prevents Fusion

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• Inhibition of Hendra Virus Fusion

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• N-Glycans on Nipah Virus Fusion Protein Protect against Neutralization but Reduce Membrane Fusion and Viral Entry

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• Using salmonid microarrays to understand the dietary modulation of carcinogenesis in rainbow trout.

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• Kinetic studies of HIV-1 and HIV-2 envelope glycoprotein-mediated fusion

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• Structure of the uncleaved ectodomain of the paramyxovirus (hPIV3) fusion protein.

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• Inhibition of Henipavirus fusion and infection by heptad-derived peptides of the Nipah virus fusion glycoprotein

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• Enfuvirtide Resistance Mutations: Impact on Human Immunodeficiency Virus Envelope Function, Entry Inhibitor Sensitivity, and Virus Neutralization

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• EphrinB2 is the entry receptor for Nipah virus, an emergent deadly paramyxovirus

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• Endocytosis Plays a Critical Role in Proteolytic Processing of the Hendra Virus Fusion Protein

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• Paramyxovirus membrane fusion: Lessons from the F and HN atomic structures

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  2005cited by this paper
• Conformational changes in HIV-1 gp41 in the course of HIV-1 envelope glycoprotein-mediated fusion and inactivation.

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• Amino Acid Substitutions in the F-Specific Domain in the Stalk of the Newcastle Disease Virus HN Protein Modulate Fusion and Interfere with Its Interaction with the F Protein

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  2004cited by this paper
• Nipah encephalitis outbreak in Malaysia.

  2003cited by this paper
• Nipah virus--a potential agent of bioterrorism?

  2003cited by this paper
• Sensitivity of HIV-1 to entry inhibitors correlates with envelope/coreceptor affinity, receptor density, and fusion kinetics

  2002cited by this paper
• Altering Expression Levels of Human Immunodeficiency Virus Type 1 gp120-gp41 Affects Efficiency but Not Kinetics of Cell-Cell Fusion

  2002cited by this paper
• Nipah virus infection: pathology and pathogenesis of an emerging paramyxoviral zoonosis.

  2002cited by this paper
• Membrane fusion machines of paramyxoviruses: capture of intermediates of fusion

  2001cited by this paper
• Nipah virus: a recently emergent deadly paramyxovirus.

  2000cited by this paper
• Isolation of Hendra virus from pteropid bats: a natural reservoir of Hendra virus.

  2000cited by this paper
• Receptor binding and membrane fusion in virus entry: the influenza hemagglutinin.

  2000cited by this paper
• Evidence That the Transition of HIV-1 Gp41 into a Six-Helix Bundle, Not the Bundle Configuration, Induces Membrane Fusion

  2000cited by this paper
• Structural basis for paramyxovirus-mediated membrane fusion.

  1999cited by this paper
• Retrovirus envelope domain at 1.7 angstrom resolution.

  1996cited by this paper
• A spring-loaded mechanism for the conformational change of influenza hemagglutinin.

  1993cited by this paper

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• Antigenic and mutational insights into the Nipah virus G glycoprotein: implications for viral entry, host specificity, therapeutics, and vaccine development

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  2024cites this paper
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  2023cites this paper
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• Nipah Virus Disease: Epidemiological, Clinical, Diagnostic and Legislative Aspects of This Unpredictable Emerging Zoonosis

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• Henipavirus membrane fusion and viral entry.

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• Emerging paramyxoviruses: molecular mechanisms and antiviral strategies

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