The Activation and Activity Control of AP‐1 (Fos/Jun)

No abstract is available for this paper.

• Publication year

  1993

• Venue

  Annals of the New York Academy of Sciences

• Publication date

  1993-06-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1111/j.1749-6632.1993.tb32277.xPMID 8317826
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Serum-, TPA-, and Ras-induced expression from Ap-1/Ets-driven promoters requires Raf-1 kinase.

  1992cited by this paper
• Casein kinase II is a negative regulator of c-Jun DNA binding and AP-1 activity.

  1992cited by this paper
• A common intermediary factor (p52/54) recognizing "acidic blob"-type domains is required for transcriptional activation by the Jun proteins

  1992cited by this paper
• Interference of pathway specific transcription factors.

  1992cited by this paper
• Interference between pathway‐specific transcription factors: glucocorticoids antagonize phorbol ester‐induced AP‐1 activity without altering AP‐1 site occupation in vivo.

  1992cited by this paper
• Oncoprotein-mediated signalling cascade stimulates c-Jun activity by phosphorylation of serines 63 and 73

  1992cited by this paper
• Functional antagonism between c-Jun and MyoD proteins: a direct physical association.

  1992cited by this paper
• Activation of extracellular signal‐regulated kinase, ERK2, by p21ras oncoprotein.

  1992cited by this paper
• DNA damage-induced gene expression: signal transduction and relation to growth factor signaling.

  1992cited by this paper
• Phosphorylation of c-jun mediated by MAP kinases

  1991cited by this paper
• Regulation of alpha-fetoprotein gene expression by antagonism between AP-1 and the glucocorticoid receptor at their overlapping binding site.

  1991cited by this paper
• Cross-coupling of signal transduction pathways: zinc finger meets leucine zipper.

  1991cited by this paper
• Ribozyme-mediated cleavage of c-fos mRNA reduces gene expression of DNA synthesis enzymes and metallothionein.

  1991cited by this paper
• Activation of protein kinase C decreases phosphorylation of c-Jun at sites that negatively regulate its DNA-binding activity.

  1991cited by this paper
• Cross-family dimerization of transcription factors Fos/Jun and ATF/CREB alters DNA binding specificity.

  1991cited by this paper
• Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73

  1991cited by this paper
• Antagonism between retinoic acid receptors and AP-1: implications for tumor promotion and inflammation.

  1991cited by this paper
• The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation.

  1991cited by this paper
• Ha-Ras augments c-Jun activity and stimulates phosphorylation of its activation domain

  1991cited by this paper
• Raf-1 protein kinase is required for growth of induced NIH/3T3 cells

  1991cited by this paper
• Negative regulation of the rat stromelysin gene promoter by retinoic acid is mediated by an AP1 binding site.

  1990cited by this paper
• Requirement for integration of signals from two distinct phosphorylation pathways for activation of MAP kinase

  1990cited by this paper
• Expression of raf family proto-oncogenes in normal mouse tissues.

  1990cited by this paper
• Distinct classes of transcriptional activating domains function by different mechanisms.

  1990cited by this paper
• Jun-Fos and receptors for vitamins A and D recognize a common response element in the human osteocalcin gene.

  1990cited by this paper
• Functional antagonism between oncoprotein c-Jun and the glucocorticoid receptor.

  1990cited by this paper
• Antitumor promotion and antiinflammation: down-modulation of AP-1 (Fos/Jun) activity by glucocorticoid hormone.

  1990cited by this paper
• A Major Decision: Proliferation or Differentiation. Interactions Between Pathwayspecific Transcription Factors Exemplify a Molecular Mechanism for the Decision

  1990cited by this paper
• Suramin affects DNA synthesis in HeLa cells by inhibition of DNA polymerases.

  1990cited by this paper
• Transcription factor interactions: selectors of positive or negative regulation from a single DNA element.

  1990cited by this paper
• Activation of the ovalbumin gene by the estrogen receptor involves the fos-jun complex.

  1990cited by this paper
• Mutual transrepression of Fos and the glucocorticoid receptor: involvement of a functional domain in Fos which is absent in FosB.

  1990cited by this paper
• Selective inhibition of activated but not basal transcription by the acidic activation domain of VP16: evidence for transcriptional adaptors.

  1990cited by this paper
• Transcriptional interference between c-Jun and the glucocorticoid receptor: mutual inhibition of DNA binding due to direct protein-protein interaction.

  1990cited by this paper
• The proline-rich transcriptional activator of CTF/NF-I is distinct from the replication and DNA binding domain.

  1989cited by this paper
• UV-induced DNA damage is an intermediate step in UV-induced expression of human immunodeficiency virus type 1, collagenase, c-fos, and metallothionein

  1989cited by this paper
• Leucine repeats and an adjacent DNA binding domain mediate the formation of functional cFos-cJun heterodimers.

  1989cited by this paper
• Transcriptional regulation in mammalian cells by sequence-specific DNA binding proteins.

  1989cited by this paper
• Suramin, an anti‐cancer drug, inhibits protein kinase C and induces differentiation in neuroblastoma cell clone NB2A

  1989cited by this paper
• Jun and v-jun contain multiple regions that participate in transcriptional activation in an interdependent manner.

  1989cited by this paper
• The leucine repeat motif in Fos protein mediates complex formation with Jun/AP-1 and is required for transformation.

  1989cited by this paper
• Activation of DNA-binding activity in an apparently cytoplasmic precursor of the NF-kappa B transcription factor.

  1988cited by this paper
• Negative effect of the transcriptional activator GAL4

  1988cited by this paper
• How eukaryotic transcriptional activators work

  1988cited by this paper
• Oncogene jun encodes a sequence-specific trans- activator similar to AP-1

  1988cited by this paper
• Direct interaction between fos and jun nuclear oncoproteins: role of the 'leucine zipper' domain

  1988cited by this paper
• GAL4-VP16 is an unusually potent transcriptional activator

  1988cited by this paper
• The molecular heterogeneity of protein kinase C and its implications for cellular regulation

  1988cited by this paper
• The role of the leucine zipper in the fos–jun interaction

  1988cited by this paper
• Fos and Jun: the AP-1 connection.

  1988cited by this paper
• A growth factor-repressible gene associated with protein kinase C- mediated inhibition of adipocyte differentiation

  1988cited by this paper
• Rapid turnover of the platelet-derived growth factor receptor in sis-transformed cells and reversal by suramin. Implications for the mechanism of autocrine transformation.

  1988cited by this paper
• Activation of the c-fos gene by UV and phorbol ester: different signal transduction pathways converge to the same enhancer element.

  1988cited by this paper
• Activation of DNA-binding activity in an apparently cytoplasmic precursor of the NF-κB transcription factor

  1988cited by this paper
• Fos-associated protein p39 is the product of the jun proto-oncogene.

  1988cited by this paper
• Requirement for fos gene expression in the transcriptional activation of collagenase by other oncogenes and phorbol esters.

  1988cited by this paper
• Multiple and cooperative trans-activation domains of the human glucocorticoid receptor.

  1988cited by this paper
• Analysis of Sp1 in vivo reveals mutiple transcriptional domains, including a novel glutamine-rich activation motif

  1988cited by this paper
• Functional dissection of VP16, the trans-activator of herpes simplex virus immediate early gene expression.

  1988cited by this paper
• I kappa B: a specific inhibitor of the NF-kappa B transcription factor.

  1988cited by this paper
• Nuclear oncoproteins determine the genetic program in response to external stimuli.

  1988cited by this paper
• Microinjection of fos-specific antibodies blocks DNA synthesis in fibroblast cells

  1988cited by this paper
• The leucine zipper: a hypothetical structure common to a new class of DNA binding proteins.

  1988cited by this paper
• Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor.

  1987cited by this paper
• Posttranscriptional regulation of c-fos mRNA expression.

  1987cited by this paper
• Activation of transcription by two factors that bind promoter and enhancer sequences of the human metallothionein gene and SV40

  1987cited by this paper
• Human proto-oncogene c-jun encodes a DNA binding protein with structural and functional properties of transcription factor AP-1.

  1987cited by this paper
• A new class of yeast transcriptional activators.

  1987cited by this paper
• 12-O-tetradecanoyl-phorbol-13-acetate induction of the human collagenase gene is mediated by an inducible enhancer element located in the 5'-flanking region

  1987cited by this paper
• Suramin inhibition of growth factor receptor binding and mitogenicity in AKR‐2B cells

  1987cited by this paper
• Inducible production of c-fos antisense RNA inhibits 3T3 cell proliferation.

  1986cited by this paper
• Functional dissection of a eukaryotic transcriptional activator protein, GCN4 of yeast.

  1986cited by this paper
• Efficient reversion of simian sarcoma virus-transformation and inhibition of growth factor-induced mitogenesis by suramin.

  1986cited by this paper
• UV-induced extracellular factor from human fibroblasts communicates the UV response to nonirradiated cells.

  1984cited by this paper
• The Rous sarcoma virus long terminal repeat is a strong promoter when introduced into a variety of eukaryotic cells by DNA-mediated transfection.

  1982cited by this paper
• Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells

  1982cited by this paper

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  2011cites this paper
• The Molecular Regulation of MAP3K1 in Eyelid Development

  2011cites this paper
• Quantitative AP‐1 gene regulation by oxidative stress in the human retinal pigment epithelium

  2009cites this paper
• A new model of cystic fibrosis pathology: lack of transport of glutathione and its thiocyanate conjugates.

  2007cites this paper
• An association of a simultaneous nuclear and cytoplasmic localization of Fra-1 with breast malignancy

  2006cites this paper
• Neuronal Angiotensin II Type 1 Receptor Upregulation in Heart Failure: Activation of Activator Protein 1 and Jun N-Terminal Kinase

  2006cites this paper
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  2004cites this paper
• Effects of steroidal and non steroidal drugs on the neovascularization response induced by tumoral TA3 supernatant on CAM from chick embryo.

  2003cites this paper
• Angiotensin II induction of AP-1 in neurons requires stimulation of PI3-K and JNK.

  2003cites this paper
• Oxidized LDL induces transcription factor activator protein‐1 in rat mesangial cells

  2003cites this paper
• Inhibition of Ras-mediated cell proliferation by benzyloxybenzaldehyde.

  2002cites this paper
• Angiotensin At1 Receptor Signalling Pathways In Neurons

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• ANGIOTENSIN II MODULATION OF NEURONAL INTRACELLULAR SIGNALING CASCADES REGULATES SHORT-TERM AND LONG-TERM PHYSIOLOGICAL RESPONSES

  2002influential citation
• Inhibition of Ras-Mediated Cell Proliferation by Benzyloxybenzaldehyde

  2002cites this paper
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  1999cites this paper
• Successive occupancy by immediate early transcriptional factors of the tyrosine hydroxylase gene TRE and CRE sites in PACAP-stimulated PC12 pheochromocytoma cells.

  1999cites this paper
• Cellular enrichment with polyunsaturated fatty acids induces an oxidative stress and activates the transcription factors AP1 and NFkappaB.

  1999cites this paper
• Transcriptional inhibition of stromelysin by interferon‐γ in normal human fibroblasts is mediated by the AP‐1 domain

  1999cites this paper
• Angiotensin II stimulates activation of Fos-regulating kinase and c-Jun NH2-terminal kinase in neuronal cultures from rat brain.

  1998cites this paper
• The role of oxidative stress in chemical carcinogenesis.

  1998cites this paper
• Presence of distinct AP‐1 dimers in normal and transformed rat hepatocytes under basal conditions and after epidermal growth factor stimulation

  1997cites this paper
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  1997cites this paper
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  1997cites this paper
• Osteosarcoma.

  1997cites this paper
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  1997cites this paper
• Copper and cell‐oxidized low‐density lipoprotein induces activator protein 1 in fibroblasts, endothelial and smooth muscle cells

  1997cites this paper
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  1996cites this paper
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  1996cites this paper
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  1996cites this paper
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  1996cites this paper
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  1996cites this paper
• Oxidized LDL Induces Transcription Factor Activator Protein–1 but Inhibits Activation of Nuclear Factor–κB in Human Vascular Smooth Muscle Cells

  1995cites this paper
• Immediate-early genes induced by antigen receptor stimulation.

  1995cites this paper
• Patch clamp detection of transcription factor translocation along the nuclear pore complex channel

  1995cites this paper
• Differential Regulation of JunD by Dihydroxycholecalciferol in Human Chronic Myelogenous Leukemia Cells (*)

  1995cites this paper
• Functions of Fetuin

  1995cites this paper
• The Role and Regulation of the Jun Proteins in Response to Phorbol Ester and UV Light

  1995cites this paper
• Sexual dimorphism of stress response and immune/ inflammatory reaction: the corticotropin releasing hormone perspective

  1995cites this paper
• Oxidized LDL induces transcription factor activator protein-1 but inhibits activation of nuclear factor-kappa B in human vascular smooth muscle cells.

  1995cites this paper
• The c- jun Proto-oncogene Down-regulates the Rat α-Fetoprotein Promoter in HepG2 Hepatoma Cells without Binding to DNA (*)

  1995cites this paper
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  1994cites this paper
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  1994cites this paper
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  1994cites this paper
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  1994cites this paper
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