H. Ponta

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Aliases
H Ponta, H. Ponta, Helmut Ponta
Publication record
194 papers · 19,259 citations · H-index 59

PAPERS

Inhibition of Tumor Growth and Metastasis in Pancreatic Cancer Models by Interference With CD44v6 Signaling.
201699 citationsauthor #15
Epidermal-specific deletion of CD44 reveals a function in keratinocytes in response to mechanical stress
201641 citationsauthor #11
Efficient Treatment of Metastatic Pancreatic Cancer via Targeted Inhibition of CD44v6 Signaling
20160 citationsauthor #15
Hormonal response region in the in terminal repeat can be dissociated has enhancer properties (glucocorticoid hormone induction/mouse mammary tumor virus/lot
20160 citationsauthor #1
Perspectives of CD44 targeting therapies
2014102 citationsauthor #2
c-Met recruits ICAM-1 as a coreceptor to compensate for the loss of CD44 in Cd44 null mice
201153 citationsauthor #7
A CD44v6 peptide reveals a role of CD44 in VEGFR-2 signaling and angiogenesis.
2009185 citationsauthor #10
Peptides Derived from Exon v6 of the CD44 Extracellular Domain Prevent Activation of Receptor Tyrosine Kinase and Subsequently Angiogenesis and Metastatic Spread of Tumor Cells
20091 citationsauthor #1
Chapter 4 Adhesion Proteins Meet Receptors
200846 citationsauthor #2
CD44v6 peptides block metastasis and interfere with angiogenesis
20080 citationsauthor #8
Adhesion proteins meet receptors: a common theme?
200873 citationsauthor #2
THE CD 44 PROTEIN FAMILY : ROLES IN EMBRYOGENESIS AND TUMOR PROGRESSION
20073 citationsauthor #1
Merlin/neurofibromatosis type 2 suppresses growth by inhibiting the activation of Ras and Rac.
2007233 citationsauthor #5
Haploinsufficiency of c-Met in cd44−/− Mice Identifies a Collaboration of CD44 and c-Met In Vivo
200760 citationsauthor #10
Gastric Mucosa and Diffuse-Type Human Gastric Carcinomas and Normal Differential Expression of CD 44 Splice Variants in Intestinal-Updated Version
20060 citationsauthor #8
Hepatocyte growth factor-induced Ras activation requires ERM proteins linked to both CD44v6 and F-actin.
2006200 citationsauthor #7
Late abstracts 186–187
20050 citationsauthor #264
Genes upregulated in a metastasizing human colon carcinoma cell line
200510 citationsauthor #9
Protein kinase ofAcetabularia
20050 citationsauthor #5
A five-amino-acid peptide blocks Met- and Ron-dependent cell migration.
200580 citationsauthor #3
The co-receptor function of CD44v6 towards c-Met in vitro and in vivo
20040 citationsauthor #4
Peptidic compounds and their derivatives for the Behandllung of human diseases by inhibition of signal transmission via growth factors
20040 citationsauthor #2
Human mammary carcinomas express homologues of rat metastasis-associated variants of CD44
200433 citationsauthor #7
Control of gene expression in bacteriophage T7
20044 citationsauthor #1
peptidic compounds and their derivatives for the treatment of human disease by inhibiting the signaling pathway by growth factors.
20040 citationsauthor #6
CD44: From adhesion molecules to signalling regulators
20032,436 citationsauthor #1
CD44 is required for two consecutive steps in HGF/c-Met signaling.
2002542 citationsauthor #5
CD44 variant-specific antibodies trigger hemopoiesis by selective release of cytokines from bone marrow macrophages.
200249 citationsauthor #5
Antagonistic Signaling Pathways Regulate Alternative Splicing of CD44 in T Cells
20027 citationsauthor #2
The NF2 tumor suppressor gene product, merlin, mediates contact inhibition of growth through interactions with CD44.
2001520 citationsauthor #8
Soluble CD44 inhibits melanoma tumor growth by blocking cell surface CD44 binding to hyaluronic acid
2001146 citationsauthor #6
Regulation of alternative pre‐mRNA splicing by the ERK MAP‐kinase pathway
2001192 citationsauthor #2
Heterogeneous Ribonucleoprotein A1 Is Part of an Exon-specific Splice-silencing Complex Controlled by Oncogenic Signaling Pathways*
2000106 citationsauthor #4
CD44 expression and regulation during mammary gland development and function.
200092 citationsauthor #7
CD44 Acts Both as a Growth‐ and Invasiveness‐Promoting Molecule and as a Tumor‐Suppressing Cofactor
2000174 citationsauthor #7
CD44 splice variants in draining lymph nodes precede allograft rejection of endocrine cells
19991 citationsauthor #3
Mode of action of hyaluronate enhancement of hemopoiesis
19990 citationsauthor #5
Hyaluronate-enhanced hematopoiesis: two different receptors trigger the release of interleukin-1beta and interleukin-6 from bone marrow macrophages.
199977 citationsauthor #5
Inhibition of MT-450 rat mammary tumour growth by antibodies recognising subtypes of blood group antigen B
199923 citationsauthor #6
Prognostic value of CD44 variant expression in primary breast cancer
199964 citationsauthor #7
CD44 variant exon v5 encodes a tyrosine that is sulphated.
199818 citationsauthor #4
The CD44 protein family: roles in embryogenesis and tumor progression.
199820 citationsauthor #1
Identification of IHABP, a 95 kDa intracellular hyaluronate binding protein.
199893 citationsauthor #9
Coupling of signal transduction to alternative pre‐mRNA splicing by a composite splice regulator
1998179 citationsauthor #2
Two different functions for CD44 proteins in human myelopoiesis.
199859 citationsauthor #6
The CD44 protein family.
199888 citationsauthor #1
Activation-dependent modulation of hyaluronate-receptor expression and of hyaluronate-avidity by human monocytes.
199827 citationsauthor #8
Molecules in focus The CD44 protein family
1998148 citationsauthor #1
CD44 variant isoforms are essential for the function of epidermal Langerhans cells and dendritic cells.
199833 citationsauthor #9
Using anti-CD44 antibodies containing preparations for the treatment of certain tumors and for the suppression of immune responses
19970 citationsauthor #2
Variant Exons v6 and v7 Together Expand the Repertoire of Glycosaminoglycans Bound by CD44*
1997105 citationsauthor #4
Molecular functions of the tumor progession protein CD44
19970 citationsauthor #1
Methods to prepare mutated CD44 surface proteins and these proteins are active against the antibodies
19970 citationsauthor #2
Efficient lysis of CD44v7/8-presenting target cells by genetically engineered cytotoxic T-lymphocytes--a model for immunogene therapy of cervical cancer.
199715 citationsauthor #6
An Essential Role for CD44 Variant Isoforms in Epidermal Langerhans Cell and Blood Dendritic Cell Function
1997188 citationsauthor #11
CD44 expression is aberrant in benign Schwann cell tumors possessing mutations in the neurofibromatosis type 2, but not type 1, gene.
199725 citationsauthor #8
Interdomain binding mediates tumor growth suppression by the NF2 gene product
1997239 citationsauthor #6
The privilege of expressing CD44v cells, misused by tumour cells.
19960 citationsauthor #3
Growth retardation of tumors by adoptive transfer of cytotoxic T lymphocytes reprogrammed by CD44V6‐specific SCFV: ζ‐chimera
199661 citationsauthor #7
Hyaluronate-independent metastatic behavior of CD44 variant-expressing pancreatic carcinoma cells.
1996102 citationsauthor #8
The CD44 proteins in embryonic development and in cancer.
199679 citationsauthor #6
Accelerated immune response in transgenic mice expressing rat CD44v4-v7 on T cells.
199641 citationsauthor #5
Expression of CD44 isoforms in human skin cancer.
199632 citationsauthor #7
The privilege of expressing CD44v - used by immune cells, misused by tumour cells
19961 citationsauthor #3
A Splice Variant of CD44 Expressed in the Rat Apical Ectodermal Ridge Contributes to Limb Outgrowth
199615 citationsauthor #4
Increasing incidence of CD44v7/8 epitope expression during uterine cervical carcinogenesis
199632 citationsauthor #9
Regulated clustering of variant CD44 proteins increases their hyaluronate binding capacity
1996157 citationsauthor #6
Means for identifying and treatment of metastatic tumors
19960 citationsauthor #2
CD44 in colon cancer.
199583 citationsauthor #3
Schwann cell tumors express characteristic patterns of CD44 splice variants
199514 citationsauthor #5
The role of CD44 splice variants in human metastatic cancer.
199540 citationsauthor #6
Comparison of immunohistochemistry and RT‐PCR for detection of CD44v‐expression, a new prognostic factor in human breast cancer
1995159 citationsauthor #8
CD44 variant exon epitopes in primary breast cancer and length of survival.
1995382 citationsauthor #4
Relevance of CD44 Variant Epitopes for Diagnosis and Therapy of Human Breast Cancer
19952 citationsauthor #1
in Colon Cancer
199512 citationsauthor #3
Expression of variant CD44 epitopes in human astrocytic brain tumors
199538 citationsauthor #8
Hyaluronate receptors: key players in growth, differentiation, migration and tumor progression.
1994437 citationsauthor #4
A distinct modulating domain in glucocorticoid receptor monomers in the repression of activity of the transcription factor AP‐1.
1994544 citationsauthor #4
Analysis of molecular functions of the tumor metastasis promoting surface molecule CD44v4-v7 using transgenic mice.
199410 citationsauthor #7
Mutual cross-modulation of steroid/retinoic acid receptor and AP-1 transcription factor activities: a novel property with practical implications.
199452 citationsauthor #2
Recent advances in the genetics of metastasis.
199419 citationsauthor #1
CD44 isoforms in metastatic cancer.
199442 citationsauthor #1
A new method to detect metastasis-associated CD44-splice variants (CD44v) in paraffin-embedded specimen of human skin cancer
19940 citationsauthor #7
By exon v5 of the CD44 gene encoded polypeptides as targets for immunotherapy and immunoscintigraphy of tumors
19930 citationsauthor #2
CD44 splice variants: metastases meet lymphocytes.
1993276 citationsauthor #4
The two major CD44 proteins expressed on a metastatic rat tumor cell line are derived from different splice variants: each one individually suffices to confer metastatic behavior.
1993246 citationsauthor #6
CD44 in Normal Differentation and Tumor Progression
19930 citationsauthor #10
CD44 splice variants; expression on lymphocytes and in neoplasia.
199327 citationsauthor #3
CD44 splice variants: metastases lyrnphocytes
19930 citationsauthor #4
Cd44 and Splice Variants of Cd44 in Normal Differentiation and Tumor Progression
199332 citationsauthor #13
Prevention of tumor metastasis formation by anti-variant CD44
1993356 citationsauthor #6
CD44 splice variants in tumor metastasis
19930 citationsauthor #6
Activated human lymphocytes and aggressive non-Hodgkin's lymphomas express a homologue of the rat metastasis-associated variant of CD44
1993342 citationsauthor #6
A link between ras and metastatic behavior of tumor cells: ras induces CD44 promoter activity and leads to low-level expression of metastasis-specific variants of CD44 in CREF cells.
1993161 citationsauthor #9
Expression of CD44 variant proteins in human colorectal cancer is related to tumor progression.
1993589 citationsauthor #6
A Dominant Metastogene Confers Metastatic Potential to Tumor Cells
19930 citationsauthor #1
A human homologue of the rat metastasis-associated variant of CD44 is expressed in colorectal carcinomas and adenomatous polyps
1993386 citationsauthor #5
Differential expression of CD44 splice variants in intestinal- and diffuse-type human gastric carcinomas and normal gastric mucosa.
1993212 citationsauthor #7
The Activation and Activity Control of AP‐1 (Fos/Jun)
199359 citationsauthor #8
CD44 splice variants: expression during lymphocyte activation and tumor progression.
199320 citationsauthor #7

TIMELINE

1970 14 citations

1971 41 citations

1972 55 citations

1974 7 citations

1975 246 citations

1976 13 citations

1977 46 citations

1978 22 citations

1979 4 citations

1980 30 citations

1981 29 citations

1982 78 citations

1983 31 citations

1984 42 citations

1985 201 citations

1986 24 citations

1987 252 citations

1988 727 citations

1989 394 citations

1990 1,646 citations

1991 2,157 citations

1992 951 citations

1993 3,012 citations

1994 1,104 citations

1995 730 citations

1996 520 citations

1997 572 citations

1998 665 citations

1999 165 citations

2000 372 citations

2001 858 citations

2002 598 citations

2003 2,436 citations

2004 37 citations

2005 90 citations

2006 200 citations

2007 296 citations

2008 119 citations

2009 186 citations

2011 53 citations

2014 102 citations

2016 140 citations

H. Ponta

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