Effects of tamoxifen on spinal bone density in women with breast cancer.

No abstract is available for this paper.

• Publication year

  1989

• Venue

  Journal of the National Cancer Institute

• Publication date

  1989-07-19

• Fields of study

  Medicine

• Identifiers
  DOI 10.1093/JNCI/81.14.1086PMID 2738937
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Clomiphene protects against osteoporosis in the mature ovariectomized rat

  2006cited by this paper
• Tamoxifen inhibits osteoclast-mediated resorption of trabecular bone in ovarian hormone-deficient rats.

  1988cited by this paper
• Estrogen binding, receptor mRNA, and biologic response in osteoblast-like osteosarcoma cells.

  1988cited by this paper
• Evidence of estrogen receptors in normal human osteoblast-like cells.

  1988cited by this paper
• Tamoxifen prevents the skeletal effects of ovarian hormone deficiency in rats

  1987cited by this paper
• Effects of anti-estrogens on bone in castrated and intact female rats

  1987cited by this paper
• Long term effect of oestrogen replacement therapy on bone mass as measured by dual photon absorptiometry.

  1987cited by this paper
• 17 beta-estradiol acts directly on the clonal osteoblastic cell line UMR106.

  1987cited by this paper
• Effects of the antiestrogens tamoxifen and clomiphene on bone resorption in vitro.

  1986cited by this paper
• Biochemical pharmacology of antiestrogen action.

  1984cited by this paper
• Treatment of primary breast cancer with chemotherapy and tamoxifen.

  1981cited by this paper
• Bone mineral content and estrogen receptors in patients with breast cancer.

  1979cited by this paper
• Oestrogen binding proteins in bone cell cytosol

  1978cited by this paper
• Nonsteroidal antiestrogens: their biological effects and potential mechanisms of action.

  1978cited by this paper
• Tamoxifen (antiestrogen) therapy in advanced breast cancer.

  1977cited by this paper
• Tamoxifen is a potent ‘pure’ anti-oestrogen in chick oviduct

  1977cited by this paper
• Influence of estrogens on bone resorption in organ culture

  1977cited by this paper
• The ultrastructural effect of estrogens on bone cells in thyroparathyroidectomized rats.

  1977cited by this paper
• Failure of estrogens and androgens to inhibit bone resorption in tissue culture.

  1976cited by this paper
• Estrogen Receptors in Bone An Evaluation of the Uptake of Estrogen into Bone Cells 1

  1974cited by this paper
• Oestrogen Replacement Therapy for Prevention of Osteoporosis after Oophorectomy

  1973cited by this paper
• Structure-activity relationships of anti-oestrogens with regard to interaction with 17-beta-oestradiol in the mouse uterus and vagina.

  1971cited by this paper

• Endocrine Therapy for Surgeons: Practical Pearls for Managing Menopausal, Bone Loss and Sexual Adverse Effects

  2023cites this paper
• Bone Health and Cancer Therapy

  2022cites this paper
• Tamoxifen: The Past, Present, and Future of a Previous Orphan Drug

  2022cites this paper
• Selective Estrogen Receptor Modulators (SERMs)

  2021cites this paper
• Current and emerging estrogen receptor-targeted therapies for the treatment of breast cancer.

  2021cites this paper
• Role of microbiota-derived short-chain fatty acids in cancer development and prevention.

  2021cites this paper
• Breast Cancer: Lifestyle, the Human Gut Microbiota/Microbiome, and Survivorship.

  2020cites this paper
• Biochemical and immunohistochemical investigations on bone formation and remodelling in ovariectomized rats with tamoxifen citrate administration.

  2019cites this paper
• 1Introduction

  2019cites this paper
• Tamoxifen a pioneering drug: An update on the therapeutic potential of tamoxifen derivatives.

  2018cites this paper
• Tamoxifen Effects on the lipid profile in premenopausal women with Breast cancer: A follow up study

  2018cites this paper
• The tamoxifen paradox—influence of adjuvant tamoxifen on fracture risk in pre- and postmenopausal women with breast cancer

  2018cites this paper
• Selective Estrogen Receptor Modulators – an Update (Joint Statement by the German Society for Gynecological Endocrinology and Reproductive Medicine [DGGEF] and the German Professional Association of Gynecologists [BVF])

  2016cites this paper
• Breast cancer survivorship: a comprehensive review of long-term medical issues and lifestyle recommendations.

  2015cites this paper
• Adjuvant Endocrine Therapy and Bone Health in Breast Cancer

  2015cites this paper
• Cancer Treatment-Induced Bone Loss in women with breast cancer.

  2015cites this paper
• Endometrial evaluation by ultrasonography, hysteroscopy and histopathology in cases of breast carcinoma on Tamoxifen therapy

  2015cites this paper
• Stock identification of neon flying squid ( Ommastrephes bartramii ) in the North Pacific Ocean on the basis of beak and statolith morphology

  2014cites this paper
• From empirical to mechanism-based discovery of clinically useful Selective Estrogen Receptor Modulators (SERMs).

  2014cites this paper
• Breast Cancer and Osteoporosis - Management of Cancer Treatment-Induced Bone Loss in Postmenopausal Women with Breast Cancer

  2014cites this paper
• Pathophysiologie und Behandlung der therapieinduzierten Osteoporose

  2014cites this paper
• Osteo-Odyssey: a Memoir

  2013cites this paper
• The Wisconsin Story in the 1980s: Discovery of Target Site-Specific Estrogen Action

  2013cites this paper
• Tamoxifen as Adjuvant Therapy in Breast Cancer

  2012cites this paper
• Selective Estrogen Receptor Modulators

  2012cites this paper
• An electrochemical outlook on tamoxifen biotransformation: current and future prospects.

  2011influential citation
• Bisphosphonates: molecular mechanisms of action and effects on bone cells, monocytes and macrophages.

  2010cites this paper
• Development of Estrogen Antagonists as Pharmaceutical Agents

  2010cites this paper
• Mechanical Loading-Related Bone Gain Is Enhanced by Tamoxifen but Unaffected by Fulvestrant in Female Mice

  2010cites this paper
• Prevention of bone loss after withdrawal of tamoxifen.

  2008cites this paper
• Bone Health and Coronary Heart Disease in Postmenopausal Women with Breast Cancer Treated with Tamoxifen: A Dissertation

  2008cites this paper
• Osteoporosis Associated with Cancer Therapy

  2008cites this paper
• Selective Estrogen Receptor Modulators for Postmenopausal Osteoporosis

  2007cites this paper
• Bone health in postmenopausal women with early breast cancer: how protective is tamoxifen?

  2007cites this paper
• Successful Translation Research with Selective Oestrogen Receptor Modulators to Treat and Prevent Breast Cancer

  2007cites this paper
• Development and evolution of therapies targeted to the estrogen receptor for the treatment and prevention of breast cancer.

  2007cites this paper
• Cancer-treatment-induced bone loss, part 1.

  2006cites this paper
• Selective estrogen receptor modulators: tissue actions and potential for CNS protection.

  2006cites this paper
• Improvements in tumor targeting, survivorship, and chemoprevention pioneered by tamoxifen. A personal perspective.

  2006cites this paper
• Endocrine therapy for breast cancer

  2006cites this paper
• Special Lecture Development of Antiestrogens and Their Use in Breast Cancer : Eighth Cain Memorial Award Lecture 1

  2006cites this paper
• Metal complex SERMs (selective oestrogen receptor modulators). The influence of different metal units on breast cancer cell antiproliferative effects.

  2006cites this paper
• Estrogen receptors as therapeutic targets in breast cancer.

  2006cites this paper
• Identification of a novel, orally bioavailable estrogen receptor downregulator

  2005cites this paper
• Ovarian status influences the skeletal effects of tamoxifen in adult rats

  2005cites this paper
• Bone Mineral Density and Lipid Changes During 5 Years of Follow-up in a Study of Prevention of Breast Cancer with Toremifene in Healthy, High-risk Pre- and Post-menopausal Women

  2005cites this paper
• Skeletal effects of estrogen analogs

  2005cites this paper
• In Vitro, Ex Vivo, and In Vivo Methodological Approaches for Studying Therapeutic Targets of Osteoporosis and Degenerative Joint Diseases: How Biomarkers Can Assist?

  2005cites this paper
• Elemental composition of bone minerals in women with breast cancer treated with adjuvant tamoxifen

  2005cites this paper
• Effects of chemotherapy-induced ovarian failure on bone and lipid metabolism in premenopausal breast cancer patients : Impact of adjuvant clodronate and tamoxifen

  2005cites this paper
• Apparent beneficial effects of tamoxifen on bone mineral content in patients with breast cancer: Preliminary study

  2005cites this paper
• Who will benefit from treatment with selective estrogen receptor modulators (SERMs)?

  2005cites this paper
• The Role of Adjuvant Therapy with Bisphosphonates in Cancer

  2004cites this paper
• Effects of drug treatment for malignancy on skeletal health of cancer survivors

  2004cites this paper
• Molecular Basis of Breast Cancer

  2004cites this paper
• “Studies on the estrogen receptor in breast cancer” — 20 years as a target for the treatment and prevention of cancer

  2004cites this paper
• Preventive Strategies in Breast Cancer

  2004cites this paper
• The Estrogen Receptor: A Logical Target for the Prevention of Breast Cancer with Antiestrogens

  2004cites this paper
• Antiestrogens and selective estrogen receptor modulators as multifunctional medicines. 2. Clinical considerations and new agents.

  2003cites this paper
• Selective estrogen receptors modulators in the prevention and treatment of postmenopausal osteoporosis.

  2003cites this paper
• Origin and characteristics of adverse events in aromatase inhibition therapy for breast cancer.

  2003cites this paper
• Selective Estrogen Receptor Modulators

  2003cites this paper
• Osteoporoserisiko nach adjuvanter Therapie des Mammakarzinoms

  2003cites this paper
• Antiestrogens and selective estrogen receptor modulators as multifunctional medicines. 1. Receptor interactions.

  2003cites this paper
• Selective estrogen-receptor modulators -- mechanisms of action and application to clinical practice.

  2003cites this paper
• Bone marrow micrometastasis in breast cancer

  2003cites this paper
• The estrogen receptor: a model for molecular medicine.

  2003cites this paper
• Female Sex Hormones, Contraceptives, And Fertility Drugs

  2003cites this paper
• Effects of SERMs on Bone in Clinical Studies

  2002cites this paper
• Trait Anxiety and Tamoxifen Effects on Bone Mineral Density and Sex Hormone- Binding Globulin

  2002cites this paper
• Bisphosphonates: biological response modifiers in breast cancer.

  2002cites this paper
• The evolution of tamoxifen therapy in breast cancer: selective oestrogen-receptor modulators and downregulators.

  2002cites this paper
• SERMs in postmenopausal Women’s health

  2002cites this paper
• Insights into the Molecular Mechanism of SERMs Through New Laboratory Models

  2002cites this paper
• Role of antiestrogens and aromatase inhibitors in breast cancer treatment

  2002cites this paper
• Hormonal Manipulations and Breast Cancer

  2002cites this paper
• Human Osteoblasts' Proliferative Responses to Strain and 17β‐Estradiol Are Mediated by the Estrogen Receptor and the Receptor for Insulin‐Like Growth Factor I

  2002cites this paper
• [Specific estrogen receptor modulators (SERMs)].

  2002cites this paper
• Effects of Oestradiol and the Oestrogen Antagonist lei 182,780 on the Delayed Type Hypersensitivity (DTH) Index and on Serum Levels of lgM and lgG in Ovariectomised Balb/C and MRL/Mp-Lpr/Lpr Mice, a Model of Systemic Lupus Erythematosus (SLE)

  2001cites this paper
• Selective Estrogen Receptor Modulators (SERMs)

  2001cites this paper
• Selective estrogen receptor modulators: the ideal estrogen replacement?(2)(2).

  2001cites this paper
• New strategies for the treatment of breast cancer

  2001cites this paper
• Breast cancer chemoprevention: current status and future directions.

  2001cites this paper
• Pure Antiestrogens and Breast

  2001cites this paper
• Selective Estrogen Receptor Modulation : A Personal Perspective 1

  2001cites this paper
• Selective Estrogen Receptor Modulation

  2001cites this paper
• Pure Antiestrogens and Breast Cancer

  2001cites this paper
• Clinical use of selective estrogen receptor modulators

  2001cites this paper
• Selective estrogen receptor modulation: a personal perspective.

  2001cites this paper
• Preventive health care for older women: Life-style recommendations and new directions

  2000cites this paper
• 93 – The Risks and Benefits of Hormone Replacement Therapy—Weighing the Evidence

  2000cites this paper
• Breast cancer chemoprevention.

  2000cites this paper
• Hormones, Estrogens and Antiestrogens

  2000cites this paper
• Strain differences in binding properties of estrogen receptors in immature and adult BALB/c and MRL/MP-lpr/lpr mice, a model of systemic lupus erythematosus.

  2000cites this paper
• The potential role of bisphosphonates as adjuvant therapy in the prevention of bone metastases

  2000cites this paper
• Factors implicated in the decision whether or not to join the tamoxifen trial in women at high familial risk of breast cancer

  2000cites this paper
• Résultats cliniques des modulateurs sélectifs du récepteur des estrogènes (SERM)

  2000cites this paper
• A pharmacological review of selective oestrogen receptor modulators.

  2000cites this paper
• Selective Estrogen Receptor Modulators (SERMs) in Clinical Practice

  2000cites this paper
• Safety a nd E fficacy R esults o f a R andomized T rial Comparing A djuvant T oremifene a nd T amoxifen in P ostmenopausal P atients W ith N ode-Positive Breast C ancer

  2000cites this paper