Nanotherapies for Treatment of Cardiovascular Disease: a Case for Antioxidant Targeted Delivery

No abstract is available for this paper.

• Publication year

  2019

• Venue

  Current Pathobiology Reports

• Publication date

  2019-06-27

• Fields of study

  Medicine, Materials Science, Environmental Science

• Identifiers
  DOI 10.1007/s40139-019-00196-4PMID 31396435PMCID PMC6687073
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Cardiovascular therapies utilizing targeted delivery of nanomedicines and aptamers

  2019cited by this paper
• Nanoparticle Therapy for Vascular Diseases

  2019cited by this paper
• Targeted Transfection Using PEGylated Cationic Liposomes Directed Towards P-Selectin Increases siRNA Delivery into Activated Endothelial Cells

  2019cited by this paper
• Atheroma Niche‐Responsive Nanocarriers for Immunotherapeutic Delivery

  2019cited by this paper
• Neutrophil Membrane-Derived Nanovesicles Alleviate Inflammation To Protect Mouse Brain Injury from Ischemic Stroke.

  2019cited by this paper
• The effects of stenting on coronary endothelium from a molecular biological view: Time for improvement?

  2018cited by this paper
• PECAM‐1 directed re‐targeting of exogenous mRNA providing two orders of magnitude enhancement of vascular delivery and expression in lungs independent of apolipoprotein E‐mediated uptake

  2018cited by this paper
• Spatially controlled assembly of affinity ligand and enzyme cargo enables targeting ferritin nanocarriers to caveolae.

  2018cited by this paper
• Vascular Targeting of Radiolabeled Liposomes with Bio-Orthogonally Conjugated Ligands: Single Chain Fragments Provide Higher Specificity than Antibodies.

  2018cited by this paper
• E‐selectin‐targeted copolymer reduces atherosclerotic lesions, adverse cardiac remodeling, and dysfunction

  2018cited by this paper
• Targeting extracellular vesicles to injured tissue using membrane cloaking and surface display

  2018cited by this paper
• Role of oxidative stress in the process of vascular remodeling following coronary revascularization.

  2018cited by this paper
• Nitric Oxide-Delivering High-Density Lipoprotein-like Nanoparticles as a Biomimetic Nanotherapy for Vascular Diseases.

  2018cited by this paper
• Insights on Localized and Systemic Delivery of Redox-Based Therapeutics

  2018cited by this paper
• Comparison of in vivo targeting ability between cRGD and collagen‐targeting peptide conjugated nano‐carriers for atherosclerosis

  2018cited by this paper
• Anionic nanoliposomes reduced atherosclerosis progression in Low Density Lipoprotein Receptor (LDLR) deficient mice fed a high fat diet

  2018cited by this paper
• Peptide Amphiphile Nanostructures for Targeting of Atherosclerotic Plaque and Drug Delivery

  2018cited by this paper
• A Targeting Nanotherapy for Abdominal Aortic Aneurysms.

  2018cited by this paper
• Targeting superoxide dismutase to endothelial caveolae profoundly alleviates inflammation caused by endotoxin

  2018cited by this paper
• Targeted Nanotherapeutics Encapsulating Liver X Receptor Agonist GW3965 Enhance Antiatherogenic Effects without Adverse Effects on Hepatic Lipid Metabolism in Ldlr−/− Mice

  2017cited by this paper
• Murine Models of Heart Failure With Preserved Ejection Fraction

  2017cited by this paper
• Corrigendum to “Development of a Doxycycline Hydrochloride-Loaded Electrospun Nanofibrous Membrane for GTR/GBR Applications”

  2016cited by this paper
• Size and targeting to PECAM vs ICAM control endothelial delivery, internalization and protective effect of multimolecular SOD conjugates.

  2016cited by this paper
• RGD targeting of human ferritin iron oxide nanoparticles enhances in vivo MRI of vascular inflammation and angiogenesis in experimental carotid disease and abdominal aortic aneurysm

  2016cited by this paper
• Nanoparticle-Based Medicines: A Review of FDA-Approved Materials and Clinical Trials to Date

  2016cited by this paper
• Reversal of Vascular Calcification and Aneurysms in a Rat Model Using Dual Targeted Therapy with EDTA- and PGG-Loaded Nanoparticles

  2016cited by this paper
• Design of Nanoparticle-Based Carriers for Targeted Drug Delivery.

  2016cited by this paper
• Nox1 in cardiovascular diseases: regulation and pathophysiology.

  2016cited by this paper
• Hydrogen Peroxide‐Responsive Nanoparticle Reduces Myocardial Ischemia/Reperfusion Injury

  2016cited by this paper
• NOX isoforms in the development of abdominal aortic aneurysm

  2016cited by this paper
• Therapeutic Efficacy of an ω-3-Fatty Acid-Containing 17-β Estradiol Nano-Delivery System against Experimental Atherosclerosis

  2016cited by this paper
• Laminin Receptor-Avid Nanotherapeutic EGCg-AuNPs as a Potential Alternative Therapeutic Approach to Prevent Restenosis

  2016cited by this paper
• H2O2-responsive antioxidant polymeric nanoparticles as therapeutic agents for peripheral arterial disease.

  2016cited by this paper
• Systemic Delivery of Nanoparticles Loaded with Pentagalloyl Glucose Protects Elastic Lamina and Prevents Abdominal Aortic Aneurysm in Rats

  2016cited by this paper
• Oxidative stress and abdominal aortic aneurysm: potential treatment targets.

  2016cited by this paper
• Endogenous superoxide dismutase activation by oral administration of riboflavin reduces abdominal aortic aneurysm formation in rats.

  2016cited by this paper
• E-selectin-targeting delivery of microRNAs by microparticles ameliorates endothelial inflammation and atherosclerosis

  2016cited by this paper
• Nanoparticles responsive to the inflammatory microenvironment for targeted treatment of arterial restenosis.

  2016cited by this paper
• Targeted Nitric Oxide Delivery by Supramolecular Nanofibers for the Prevention of Restenosis After Arterial Injury

  2016cited by this paper
• Formulation, characteristics and antiatherogenic bioactivities of CD36-targeted epigallocatechin gallate (EGCG)-loaded nanoparticles.

  2016cited by this paper
• Targeted Interleukin-10 Nanotherapeutics Developed with a Microfluidic Chip Enhance Resolution of Inflammation in Advanced Atherosclerosis.

  2016cited by this paper
• Fibrinolytic PLGA nanoparticles for slow clot lysis within abdominal aortic aneurysms attenuate proteolytic loss of vascular elastic matrix.

  2016cited by this paper
• Sugar-based amphiphilic nanoparticles arrest atherosclerosis in vivo

  2015cited by this paper
• Prevention of abdominal aortic aneurysm progression by targeted inhibition of matrix metalloproteinase activity with batimastat-loaded nanoparticles.

  2015cited by this paper
• Reperfusion injury and reactive oxygen species: The evolution of a concept☆

  2015cited by this paper
• Modified VEGF targets the ischemic myocardium and promotes functional recovery after myocardial infarction.

  2015cited by this paper
• Nanoparticle biointerfacing via platelet membrane cloaking

  2015cited by this paper
• Ultrasmall superparamagnetic iron oxide nanoparticles coated with fucoidan for molecular MRI of intraluminal thrombus.

  2015cited by this paper
• Targeted nanoparticles containing the proresolving peptide Ac2-26 protect against advanced atherosclerosis in hypercholesterolemic mice

  2015cited by this paper
• Multifunctional Nanoparticles Facilitate Molecular Targeting and miRNA Delivery to Inhibit Atherosclerosis in ApoE–/– Mice

  2015cited by this paper
• Inhibition of atherosclerosis-promoting microRNAs via targeted polyelectrolyte complex micelles.

  2014cited by this paper
• Dual-Modal Magnetic Resonance and Fluorescence Imaging of Atherosclerotic Plaques in Vivo Using VCAM-1 Targeted Tobacco Mosaic Virus

  2014cited by this paper
• Targeting to Endothelial Cells Augments the Protective Effect of Novel Dual Bioactive Antioxidant/Anti-Inflammatory Nanoparticles

  2014cited by this paper
• Endothelial targeting of nanocarriers loaded with antioxidant enzymes for protection against vascular oxidative stress and inflammation.

  2014cited by this paper
• Endothelial targeting of liposomes encapsulating SOD/catalase mimetic EUK-134 alleviates acute pulmonary inflammation.

  2014cited by this paper
• Active targeting of early and mid-stage atherosclerotic plaques using self-assembled peptide amphiphile micelles.

  2014cited by this paper
• Oxidative stress and pathological changes after coronary artery interventions.

  2013cited by this paper
• Reduction of nanoparticle avidity enhances the selectivity of vascular targeting and PET detection of pulmonary inflammation.

  2013cited by this paper
• Integrin-Targeted Molecular Imaging of Experimental Abdominal Aortic Aneurysms by 18F-labeled Arg-Gly-Asp Positron-Emission Tomography

  2013cited by this paper
• Overexpression of Catalase in Vascular Smooth Muscle Cells Prevents the Formation of Abdominal Aortic Aneurysms

  2013cited by this paper
• Antioxidant protection by PECAM-targeted delivery of a novel NADPH-oxidase inhibitor to the endothelium in vitro and in vivo.

  2012cited by this paper
• Catalase overexpression in aortic smooth muscle prevents pathological mechanical changes underlying abdominal aortic aneurysm formation.

  2011cited by this paper
• In vivo characterization of a new abdominal aortic aneurysm mouse model with conventional and molecular magnetic resonance imaging.

  2011cited by this paper
• Molecular targeting of atherosclerotic plaques by a stabilin-2-specific peptide ligand.

  2011cited by this paper
• Specific penetration and accumulation of a homing peptide within atherosclerotic plaques of apolipoprotein E-deficient mice

  2011cited by this paper
• Immunoliposomal drug-delivery system targeting lectin-like oxidized low-density lipoprotein receptor-1 for carotid plaque lesions in rats.

  2011cited by this paper
• In vivo prevention of arterial restenosis with paclitaxel-encapsulated targeted lipid–polymeric nanoparticles

  2011cited by this paper
• Oxidative stress changes after stent implantation: a randomized comparative study of sirolimus-eluting and bare metal stents.

  2010cited by this paper
• Annexin A5-functionalized bimodal nanoparticles for MRI and fluorescence imaging of atherosclerotic plaques.

  2010cited by this paper
• Diagnosis and monitoring of abdominal aortic aneurysm: current status and future prospects.

  2010cited by this paper
• Targeting VEGF‐encapsulated immunoliposomes to MI heart improves vascularity and cardiac function

  2009cited by this paper
• Mechanisms of Vascular Smooth Muscle NADPH Oxidase 1 (Nox1) Contribution to Injury-Induced Neointimal Formation

  2009cited by this paper
• Endothelial dysfunction and vascular disease

  2009cited by this paper
• Myeloperoxidase: Molecular Mechanisms of Action and Their Relevance to Human Health and Disease

  2009cited by this paper
• Mammalian Heme Peroxidases: From Molecular Mechanisms to Health Implications

  2008cited by this paper
• Involvement of Nox2 NADPH Oxidase in Adverse Cardiac Remodeling After Myocardial Infarction

  2008cited by this paper
• Reconciling the chemistry and biology of reactive oxygen species.

  2008cited by this paper
• Redox Control of Endothelial Function and Dysfunction: Molecular Mechanisms and Therapeutic Opportunities

  2008cited by this paper
• Antiangiogenic synergism of integrin-targeted fumagillin nanoparticles and atorvastatin in atherosclerosis.

  2008cited by this paper
• Prognostic role of flow-mediated dilation and cardiac risk factors in post-menopausal women.

  2008cited by this paper
• Extracellular superoxide dismutase accelerates endothelial recovery and inhibits in-stent restenosis in stented atherosclerotic Watanabe heritable hyperlipidemic rabbit aorta.

  2007cited by this paper
• Nitric oxide and peroxynitrite in health and disease.

  2007cited by this paper
• Localization to atherosclerotic plaque and biodistribution of biochemically derivatized superparamagnetic iron oxide nanoparticles (SPIONs) contrast particles for magnetic resonance imaging (MRI)

  2007cited by this paper
• NADPH Oxidases in Cardiovascular Health and Disease

  2006cited by this paper
• Noninvasive Vascular Cell Adhesion Molecule-1 Imaging Identifies Inflammatory Activation of Cells in Atherosclerosis

  2006cited by this paper
• In Vivo Phage Display Selection Yields Atherosclerotic Plaque Targeted Peptides for Imaging

  2006cited by this paper
• NO-independent stimulators and activators of soluble guanylate cyclase: discovery and therapeutic potential

  2006cited by this paper
• Deletion of p47phox Attenuates Angiotensin II–Induced Abdominal Aortic Aneurysm Formation in Apolipoprotein E–Deficient Mice

  2006cited by this paper
• Endothelial dysfunction: a multifaceted disorder (The Wiggers Award Lecture).

  2006cited by this paper
• Extracellular superoxide dismutase overexpression reduces cuff-induced arterial neointimal formation.

  2005cited by this paper
• Redox Processes Underlying the Vascular Repair Reaction

  2004cited by this paper
• Retardation of Atherosclerosis by Overexpression of Catalase or Both Cu/Zn-Superoxide Dismutase and Catalase in Mice Lacking Apolipoprotein E

  2004cited by this paper
• Decreased neointimal formation in Nox2-deficient mice reveals a direct role for NADPH oxidase in the response to arterial injury.

  2004cited by this paper
• Role of oxidative modifications in atherosclerosis.

  2004cited by this paper
• Coronary Endothelial Dysfunction Is Associated With an Increased Risk of Cerebrovascular Events

  2003cited by this paper
• Sustained Decrease in Superoxide Dismutase Activity Underlies Constrictive Remodeling After Balloon Injury in Rabbits

  2003cited by this paper
• Role of p47phox in Vascular Oxidative Stress and Hypertension Caused by Angiotensin II

  2002cited by this paper
• Adenovirus-Mediated Extracellular Superoxide Dismutase Gene Therapy Reduces Neointima Formation in Balloon-Denuded Rabbit Aorta

  2002cited by this paper
• Inflammation and Atherosclerosis

  2002cited by this paper
• Risk Stratification for Postoperative Cardiovascular Events via Noninvasive Assessment of Endothelial Function: A Prospective Study

  2002cited by this paper

• Next-Generation Antioxidants in Cardiovascular Disease: Mechanistic Insights and Emerging Therapeutic Strategies.

  2026cites this paper
• Cardiometabolic shock: understanding the final turns of the downward spiral

  2025cites this paper
• Linking oxidative stress biomarkers to disease progression and antioxidant therapy in hypertension and diabetes mellitus

  2025cites this paper
• Augmented expression of superoxide dismutase 2 mitigates progression and rupture of experimental abdominal aortic aneurysm

  2025cites this paper
• Nanotechnological Approaches to Enhance the Potential of α-Lipoic Acid for Application in the Clinic

  2024cites this paper
• Unlocking the Power of Antioxidant Nanoparticles: Insights into Classification, Formulation, Characterization, and Biomedical Applications

  2024cites this paper
• High-density lipoprotein mimetic nano-therapeutics targeting monocytes and macrophages for improved cardiovascular care: a comprehensive review

  2024cites this paper
• Recent Advances in Cell-based Nanotherapy for Cardiovascular Diseases.

  2023cites this paper
• Immunomodulation in age-related disorders and nanotechnology interventions.

  2022cites this paper
• Preclinical study for the ameliorating effect of l-ascorbic acid for the oxidative stress of chronic administration of organic nitrates on myocardial tissue in high sucrose/fat rat model

  2022cites this paper
• Antioxidant Response Activating nanoParticles (ARAPas) localize to atherosclerotic plaque and locally activate the Nrf2 pathway

  2021cites this paper
• Delivery of Cinnamic Aldehyde Antioxidant Response Activating nanoParticles (ARAPas) for Vascular Applications

  2021cites this paper
• Nrf2 activator-encapsulating polymeric nanoparticles and LDL-like nanoparticles target atherosclerotic plaque

  2020cites this paper
• Strategies to expand the therapeutic potential of superoxide dismutase by exploiting delivery approaches.

  2020cites this paper
• Vascular Targeting of Radiolabeled Liposomes with Bio-Orthogonally Conjugated Ligands: Single Chain Fragments Provide Higher Specificity than Antibodies.

  2018cites this paper
• Insights on Localized and Systemic Delivery of Redox-Based Therapeutics

  2018cites this paper