Challenges and Persistent Questions in Treatment of Trichomoniasis.

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Current Topics in Medicinal Chemistry

• Publication date

  Unknown publication date

• Fields of study

  Medicine

• Identifiers
  DOI 10.2174/1568026616666161025162222PMID 27784254
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Management of recalcitrant Trichomonas vaginalis in pregnancy: a case report

  2016cited by this paper
• Pentamycin shows high efficacy against Trichomonas vaginalis.

  2015cited by this paper
• Genome mining offers a new starting point for parasitology research

  2015cited by this paper
• Novel Insights into the Molecular Events Linking to Cell Death Induced by Tetracycline in the Amitochondriate Protozoan Trichomonas vaginalis

  2015cited by this paper
• Dithiocarbamate-thiourea hybrids useful as vaginal microbicides also show reverse transcriptase inhibition: design, synthesis, docking and pharmacokinetic studies.

  2015cited by this paper
• Sexually transmitted diseases treatment guidelines, 2015.

  2015influential reference
• N-Alkyl/aryl-4-(3-substituted-3-phenylpropyl)piperazine-1-carbothioamide as dual-action vaginal microbicides with reverse transcriptase inhibition.

  2015influential reference
• Trichomonas vaginalis infection induces vaginal CD4+ T-cell infiltration in a mouse model: a vaccine strategy to reduce vaginal infection and HIV transmission.

  2015cited by this paper
• Successful treatment of refractory Trichomonas vaginalis infection using intravenous metronidazole

  2015cited by this paper
• The use of metronidazole during pregnancy: a review of evidence.

  2015cited by this paper
• Effect of Recombinant Prophenin 2 on the Integrity and Viability of Trichomonas vaginalis

  2015cited by this paper
• High rates of double-stranded RNA viruses and Mycoplasma hominis in Trichomonas vaginalis clinical isolates in South Brazil.

  2015cited by this paper
• Neglected Parasitic Infections in the United States: Trichomoniasis

  2014cited by this paper
• Evaluation of the effect of miltefosine on Trichomonas vaginalis

  2014cited by this paper
• Modified oral metronidazole desensitization protocol

  2014cited by this paper
• Novel metronidazole-chalcone conjugates with potential to counter drug resistance in Trichomonas vaginalis.

  2014cited by this paper
• Trichomonas vaginalis as a Cause of Perinatal Morbidity: A Systematic Review and Meta-Analysis

  2014cited by this paper
• Design and synthesis of substituted morpholin/piperidin-1-yl-carbamodithioates as promising vaginal microbicides with spermicidal potential.

  2014cited by this paper
• [Is combining metronidazole and alcohol really hazardous?].

  2014cited by this paper
• Immunity in urogenital protozoa

  2014cited by this paper
• Current status and prospects for development of a vaccine against Trichomonas vaginalis infections.

  2014cited by this paper
• United Kingdom National Guideline on the Management of Trichomonas vaginalis 2014

  2014cited by this paper
• Identification of proton-pump inhibitor drugs that inhibit Trichomonas vaginalis uridine nucleoside ribohydrolase.

  2014cited by this paper
• Toward global prevention of sexually transmitted infections (STIs): the need for STI vaccines.

  2014cited by this paper
• Male infertility: a public health issue caused by sexually transmitted pathogens

  2014cited by this paper
• Trichomonas vaginalis homolog of macrophage migration inhibitory factor induces prostate cell growth, invasiveness, and inflammatory responses

  2014cited by this paper
• Trichomonas vaginalis flavin reductase 1 and its role in metronidazole resistance

  2014cited by this paper
• Author Manuscript

  2013cited by this paper
• The Evaluation of Children in the Primary Care Setting When Sexual Abuse Is Suspected

  2013cited by this paper
• Respiratory disease and Trichomonas vaginalis in premature newborn twins.

  2013cited by this paper
• Drug library screening against metronidazole-sensitive and metronidazole-resistant Trichomonas vaginalis isolates

  2013cited by this paper
• The Estimated Direct Medical Cost of Selected Sexually Transmitted Infections in the United States, 2008

  2013cited by this paper
• Antibody to a conserved antigenic target is protective against diverse prokaryotic and eukaryotic pathogens

  2013cited by this paper
• Association of Trichomonas vaginalis with its symbiont Mycoplasma hominis synergistically upregulates the in vitro proinflammatory response of human monocytes

  2013cited by this paper
• Trichomonas vaginalis Vaginitis in Obstetrics and Gynecology Practice: New Concepts and Controversies

  2013cited by this paper
• Innovation for the 'bottom 100 million': eliminating neglected tropical diseases in the Americas.

  2013cited by this paper
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  2012cited by this paper
• Endobiont Viruses Sensed by the Human Host – Beyond Conventional Antiparasitic Therapy

  2012cited by this paper
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  2012cited by this paper
• Screening of Male Patients for Trichomonas vaginalis with Transcription-Mediated Amplification in a Community with a High Prevalence of Sexually Transmitted Infection

  2012cited by this paper
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  2012cited by this paper
• Trichomonas vaginalis Antimicrobial Drug Resistance in 6 US Cities, STD Surveillance Network, 2009–2010

  2012cited by this paper
• Trichomoniasis and Lactoferrin: Future Prospects

  2012cited by this paper
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  2012cited by this paper
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  2012cited by this paper
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  2012cited by this paper
• Female Epidemiology of Transcription-Mediated Amplification-Based Trichomonas vaginalis Detection in a Metropolitan Setting with a High Prevalence of Sexually Transmitted Infection

  2012cited by this paper
• [Sexually transmitted infections: epidemiology and control].

  2011cited by this paper
• Resistant trichomoniasis: successful treatment with combination therapy.

  2011cited by this paper
• Utility of Antimicrobial Susceptibility Testing in Trichomonas vaginalis–Infected Women With Clinical Treatment Failure

  2011cited by this paper
• New developments in aminoglycoside therapy and ototoxicity.

  2011cited by this paper
• Trichomonas vaginalis: current understanding of host-parasite interactions.

  2011cited by this paper
• Treatment of trichomoniasis in pregnancy in sub-Saharan Africa does not appear to be associated with low birth weight or preterm birth.

  2010cited by this paper
• In vitro activity of dermaseptin S1 derivatives against genital pathogens

  2010cited by this paper
• Randomized controlled trials of interventions to prevent sexually transmitted infections: learning from the past to plan for the future.

  2010cited by this paper
• Sexually transmitted infection is associated with increased risk of preterm birth in South Carolina women insured by Medicaid

  2010cited by this paper
• Neonatal Trichomonas vaginalis infection: a case report and review of literature

  2010cited by this paper
• Mycoplasma hominis infection of Trichomonas vaginalis is not associated with metronidazole-resistant trichomoniasis in clinical isolates from the United States

  2010cited by this paper
• Paromomycin treatment of recalcitrant Trichomonas vaginalis

  2010cited by this paper
• Prevention or treatment: the benefits of Trichomonas vaginalis vaccine.

  2010cited by this paper
• The burden and risk factors of Sexually Transmitted Infections and Reproductive Tract Infections among pregnant women in Zimbabwe

  2010cited by this paper
• Medical and Legal Implications of Testing for Sexually Transmitted Infections in Children

  2010cited by this paper
• The flavin inhibitor diphenyleneiodonium renders Trichomonas vaginalis resistant to metronidazole, inhibits thioredoxin reductase and flavin reductase, and shuts off hydrogenosomal enzymatic pathways.

  2010cited by this paper
• Hydrogenosomes of Laboratory‐Induced Metronidazole‐Resistant Trichomonas vaginalis Lines are Downsized While Those from Clinically Metronidazole‐Resistant Isolates Are Not

  2010cited by this paper
• Regulation of Gene Expression in Protozoa Parasites

  2010cited by this paper
• Safety, Tolerability and Pharmacokinetics of Intravaginal Pentamycin

  2010cited by this paper
• Trichomonal sinusitis in an adolescent patient with multiple trauma.

  2009cited by this paper
• Impact of T. vaginalis infection on innate immune responses and reproductive outcome.

  2009cited by this paper
• Genotoxicity Revaluation of Three Commercial Nitroheterocyclic Drugs: Nifurtimox, Benznidazole, and Metronidazole

  2009cited by this paper
• Trichomonas vaginalis: metronidazole and other nitroimidazole drugs are reduced by the flavin enzyme thioredoxin reductase and disrupt the cellular redox system. Implications for nitroimidazole toxicity and resistance

  2009cited by this paper
• Treatment of Trichomoniasis in Pregnancy and Preterm Birth: An Observational Study

  2009cited by this paper
• Treatment of metronidazole-resistant Trichomonas vaginalis.

  2009cited by this paper
• Neonatal respiratory tract involvement by Trichomonas vaginalis: a case report and review of the literature.

  2008cited by this paper
• Treatment of Vaginal Infections with Intravaginal Pentamycin in Clinical Practice

  2008cited by this paper
• Trichomonas vaginalis harboring Mycoplasma hominis increases cytopathogenicity in vitro

  2008cited by this paper
• Trichomonas vaginalis infection and human immunodeficiency virus acquisition in African women.

  2008cited by this paper
• Management of trichomonas vaginalis in women with suspected metronidazole hypersensitivity.

  2008cited by this paper
• Perinatal transmission of Trichomonas vaginalis: a case report.

  2008cited by this paper
• Early repeated infections with Trichomonas vaginalis among HIV-positive and HIV-negative women.

  2008cited by this paper
• The prevalence of Trichomonas vaginalis infection among reproductive-age women in the United States, 2001-2004.

  2007cited by this paper
• Current Therapeutics, Their Problems, and Sulfur-Containing-Amino-Acid Metabolism as a Novel Target against Infections by “Amitochondriate” Protozoan Parasites

  2007cited by this paper
• Prevalence of sexually transmitted infections in HIV-1 infected pregnant women in Europe

  2007cited by this paper
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  2007cited by this paper
• Infection with Trichomonas vaginalis increases the risk of HIV-1 acquisition.

  2007cited by this paper
• Draft Genome Sequence of the Sexually Transmitted Pathogen Trichomonas vaginalis

  2007cited by this paper
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  2006cited by this paper
• Mycoplasma hominis and Trichomonas vaginalis: a unique case of symbiotic relationship between two obligate human parasites.

  2006cited by this paper
• Use of Trichomonas vaginalis Clinical Isolates to Evaluate Correlation of Gene Expression and Metronidazole Resistance

  2006cited by this paper
• Development of a Nonhuman Primate Model for Trichomonas vaginalis Infection

  2006influential reference
• Symbiosis of Mycoplasma hominis in Trichomonas vaginalis may link metronidazole resistance in vitro

  2006cited by this paper
• Plasma Antibodies against Trichomonas vaginalis and Subsequent Risk of Prostate Cancer

  2006cited by this paper
• In vitro activity of hexadecylphosphocholine (miltefosine) against metronidazole-resistant and -susceptible strains of Trichomonas vaginalis.

  2006cited by this paper
• Antibiotics for treating bacterial vaginosis in pregnancy.

  2005cited by this paper
• Long-Term Survival and Intracellular Replication of Mycoplasma hominis in Trichomonas vaginalis Cells: Potential Role of the Protozoon in Transmitting Bacterial Infection

  2005cited by this paper
• Synthesis and biological properties of new 5-nitroindazole derivatives.

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• Premature with trichomoniasis: report of one case.

  2005cited by this paper
• Treatment of Infections Caused by Metronidazole-Resistant Trichomonas vaginalis

  2004cited by this paper
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  2003cited by this paper

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  2017cites this paper
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