A sequence compilation and comparison of exons that are alternatively spliced in neurons.

No abstract is available for this paper.

• Publication year

  1994

• Venue

  Nucleic Acids Research

• Publication date

  1994-05-11

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1093/NAR/22.9.1515PMID 8202349PMCID PMC308024
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Mechanisms for selecting 5' splice sites in mammalian pre-mRNA splicing.

  1994cited by this paper
• Fission yeast gene structure and recognition.

  1994cited by this paper
• Genomic structure of the locus encoding protein 4.1. Structural basis for complex combinational patterns of tissue-specific alternative RNA splicing.

  1993cited by this paper
• The U5 and U6 small nuclear RNAs as active site components of the spliceosome.

  1993cited by this paper
• A novel short isoform of the D3 dopamine receptor generated by alternative splicing in the third cytoplasmic loop.

  1993cited by this paper
• The cardiac troponin T alternative exon contains a novel purine-rich positive splicing element

  1993cited by this paper
• Regulation of tissue-specific splicing of the calcitonin/calcitonin gene-related peptide gene by RNA-binding proteins.

  1993cited by this paper
• A splicing enhancer in the human fibronectin alternate ED1 exon interacts with SR proteins and stimulates U2 snRNP binding.

  1993cited by this paper
• Neurexin III alpha: extensive alternative splicing generates membrane-bound and soluble forms.

  1993cited by this paper
• The role of exon sequences in splice site selection.

  1993cited by this paper
• Distinct functions of SR proteins in alternative pre-mRNA splicing.

  1993cited by this paper
• Control of calcitonin/calcitonin gene-related peptide pre-mRNA processing by constitutive intron and exon elements

  1993cited by this paper
• Glial growth factors are alternatively spliced erbB2 ligands expressed in the nervous system

  1993cited by this paper
• Mutations in U6 snRNA that alter splice site specificity: implications for the active site.

  1993cited by this paper
• Brain-specific tropomyosins TMBr-1 and TMBr-3 have distinct patterns of expression during development and in adult brain.

  1993cited by this paper
• Features of spliceosome evolution and function inferred from an analysis of the information at human splice sites.

  1992cited by this paper
• Alternative splicing of the Oct-2 transcription factor RNA is differentially regulated in neuronal cells and B cells and results in protein isoforms with opposite effects on the activity of octamer/TAATGARAT-containing promoters.

  1992cited by this paper
• Clathrin light chain B: gene structure and neuron-specific splicing.

  1992cited by this paper
• Two mRNAs Are Transcribed from the Human Gene for Choline Acetyltransferase

  1992cited by this paper
• A tissue-specific small nuclear ribonucleoprotein and the regulated splicing of the calcitonin/calcitonin gene-related protein transcript.

  1992cited by this paper
• In vitro splicing of cardiac troponin T precursors. Exon mutations disrupt splicing of the upstream intron.

  1992cited by this paper
• Cloning of a big tau microtubule-associated protein characteristic of the peripheral nervous system.

  1992cited by this paper
• Characterization of a Shaw‐related potassium channel family in rat brain.

  1992cited by this paper
• Neurexins: synaptic cell surface proteins related to the alpha-latrotoxin receptor and laminin.

  1992cited by this paper
• Activation of c-src neuron-specific splicing by an unusual RNA element in vivo and in vitro.

  1992cited by this paper
• Primary structure and alternative splice variants of gephyrin, a putative glycine receptor-tubulin linker protein.

  1992cited by this paper
• Identification and developmental expression of Src+ mRNAs in Xenopus laevis.

  1992cited by this paper
• Structure and novel exons of the human tau gene.

  1992cited by this paper
• Expression of a cDNA for a neuronal calcium channel alpha 1 subunit enhances secretion from adrenal chromaffin cells.

  1992cited by this paper
• Rat brain expresses an alternatively spliced form of the dihydropyridine-sensitive L-type calcium channel alpha 2 subunit.

  1992cited by this paper
• Mutations which alter splicing in the human hypoxanthine-guanine phosphoribosyltransferase gene.

  1992cited by this paper
• Alternatively spliced sodium channel transcripts in brain and muscle

  1992cited by this paper
• Small nuclear ribonucleoprotein polypeptide N (SNRPN), an expressed gene in the Prader–Willi syndrome critical region

  1992cited by this paper
• Prediction of gene structure.

  1992cited by this paper
• Clathrin-coated vesicles in nervous tissue are involved primarily in synaptic vesicle recycling

  1992cited by this paper
• Gene expression in cells of the central nervous system.

  1992cited by this paper
• Polypyrimidine tract binding protein interacts with sequences involved in alternative splicing of beta-tropomyosin pre-mRNA.

  1992cited by this paper
• Alternative splicing generates functionally distinct N-methyl-D-aspartate receptors.

  1992cited by this paper
• The agrin gene codes for a family of basal lamina proteins that differ in function and distribution.

  1992cited by this paper
• Differential expression of the beta I- and beta II-PKC subspecies in the postnatal developing rat brain; an immunocytochemical study.

  1991cited by this paper
• Generation of Two Forms of the γ‐Aminobutyric AcidA Receptor γ‐2‐Subunit in Mice by Alternative Splicing

  1991cited by this paper
• A rat brain mRNA encoding a transcriptional activator homologous to the DNA binding domain of retroviral integrases.

  1991cited by this paper
• Multiple Oct2 isoforms are generated by alternative splicing

  1991cited by this paper
• Molecular genetics of kinesin light chains: generation of isoforms by alternative splicing.

  1991cited by this paper
• Control of alternative splicing by the differential binding of U1 small nuclear ribonucleoprotein particle.

  1991cited by this paper
• The role of branchpoint and 3'-exon sequences in the control of balanced splicing of avian retrovirus RNA.

  1991cited by this paper
• Shaw‐like rat brain potassium channel cDNA's with divergent 3′ ends

  1991cited by this paper
• RNA editing in brain controls a determinant of ion flow in glutamate-gated channels.

  1991cited by this paper
• Glutamate-operated channels: developmentally early and mature forms arise by alternative splicing.

  1991cited by this paper
• Molecular cloning of cDNA encoding the rat neural cell adhesion molecule L1 Two L1 isoforms in the cytoplasmic region are produced by differential splicing

  1991cited by this paper
• Differential expression of the mouse D2 dopamine receptor isoforms

  1991cited by this paper
• Distinct calcium channels are generated by alternative splicing and are differentially expressed in the mammalian CNS.

  1991cited by this paper
• Shorter variants of the D3 dopamine receptor produced through various patterns of alternative splicing.

  1991cited by this paper
• Alternative splicing of beta-tropomyosin pre-mRNA: cis-acting elements and cellular factors that block the use of a skeletal muscle exon in nonmuscle cells.

  1991cited by this paper
• Alternative splicing contributes to K+ channel diversity in the mammalian central nervous system.

  1991cited by this paper
• Differential expression of two forms of GABAA receptor gamma 2-subunit in mice.

  1991cited by this paper
• Inositol 1,4,5-trisphosphate receptors: distinct neuronal and nonneuronal forms derived by alternative splicing differ in phosphorylation.

  1991cited by this paper
• Molecular cloning of a member of a third class of Shaker-family K+ channel genes in mammals.

  1991cited by this paper
• The chicken tropomyosin 1 gene generates nine mRNAs by alternative splicing.

  1991cited by this paper
• Alternative splicing generates two isoforms of the α2 subunit of the inhibitory glycine receptor

  1991cited by this paper
• Does steric interference between splice sites block the splicing of a short c-src neuron-specific exon in non-neuronal cells?

  1991cited by this paper
• Alternative splicing generates two variants of the alpha 1 subunit of the inhibitory glycine receptor.

  1991cited by this paper
• Phosphorylation of human recombinant tyrosine hydroxylase isoforms 1 and 2: an additional phosphorylated residue in isoform 2, generated through alternative splicing.

  1991cited by this paper
• Structure of the human gene and two rat cDNAs encoding the alpha chain of GTP-binding regulatory protein Go: two different mRNAs are generated by alternative splicing.

  1991cited by this paper
• gamma-Aminobutyric acidA receptor heterogeneity is increased by alternative splicing of a novel beta-subunit gene transcript.

  1991cited by this paper
• Molecular cloning of multiple subtypes of a novel rat brain isoform of the alpha 1 subunit of the voltage-dependent calcium channel.

  1991cited by this paper
• Three novel brain tropomyosin isoforms are expressed from the rat alpha-tropomyosin gene through the use of alternative promoters and alternative RNA processing

  1990cited by this paper
• Cloning and characterization of molecular isoforms of the catalytic subunit of calcineurin using nonisotopic methods.

  1990cited by this paper
• Structure, expression, and some regulatory mechanisms of the rat preprotachykinin gene encoding substance P, neurokinin A, neuropeptide K, and neuropeptide gamma

  1990cited by this paper
• Sequence of the chicken GABAA receptor gamma 2-subunit cDNA.

  1990cited by this paper
• Control of retroviral RNA splicing through maintenance of suboptimal processing signals

  1990cited by this paper
• A developmentally regulated, nervous system-specific gene in Xenopus encodes a putative RNA-binding protein.

  1990cited by this paper
• Uridine branch acceptor is a cis-acting element involved in regulation of the alternative processing of calcitonin/CGRP-l pre-mRNA.

  1990cited by this paper
• Identification by sequence analysis of a second rat brain cDNA encoding the dopamine (D2) receptor.

  1990cited by this paper
• K-tuple frequency analysis: from intron/exon discrimination to T-cell epitope mapping.

  1990cited by this paper
• Identification of a novel neuronal C-SRC exon expressed in human brain

  1990cited by this paper
• The structure of the human synapsin I gene and protein.

  1990cited by this paper
• Differential splicing generates a nervous system-specific form of Drosophila neuroglian.

  1990cited by this paper
• Another mechanism for creating diversity in gamma-aminobutyrate type A receptors: RNA splicing directs expression of two forms of gamma 2 phosphorylation site.

  1990cited by this paper
• Flip and flop: a cell-specific functional switch in glutamate-operated channels of the CNS.

  1990cited by this paper
• Expression of the unique NCAM VASE exon is independently regulated in distinct tissues during development

  1990cited by this paper
• Basic local alignment search tool.

  1990cited by this paper
• Expression of myelin basic protein isoforms in nonglial cells

  1990cited by this paper
• Exon definition may facilitate splice site selection in RNAs with multiple exons.

  1990cited by this paper
• Alternative processing of bovine growth hormone mRNA is influenced by downstream exon sequences

  1989cited by this paper
• Synapsins: mosaics of shared and individual domains in a family of synaptic vesicle phosphoproteins.

  1989cited by this paper
• Evolution of the neuron‐specific alternative splicing product of the c‐src proto‐oncogene

  1989cited by this paper
• Cloning and sequencing of the cDNA encoding an isoform of microtubule‐associated protein tau containing four tandem repeats: differential expression of tau protein mRNAs in human brain.

  1989cited by this paper
• Neuron-specific splicing of C-SRC RNA in human brain.

  1989cited by this paper
• Multiple D2 dopamine receptors produced by alternative RNA splicing

  1989cited by this paper
• Alternative splicing directs the expression of two D2 dopamine receptor isoforms

  1989cited by this paper
• Structure of the bovine tau gene: alternatively spliced transcripts generate a protein family

  1989cited by this paper
• Embryonic MAP2 lacks the cross-linking sidearm sequences and dendritic targeting signal of adult MAP2

  1989cited by this paper
• Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease.

  1989cited by this paper
• Cloning of human calcineurin A: evidence for two isozymes and identification of a polyproline structural domain.

  1989cited by this paper
• A single gene codes for two forms of rat nucleolar protein B23 mRNA.

  1989cited by this paper
• The Major Dopamine D2 Receptor: Molecular Analysis of the Human D2A Subtype

  1989cited by this paper
• Differential exon usage involving an unusual splicing mechanism generates at least eight types of NCAM cDNA in mouse brain.

  1989cited by this paper
• cDNA cloning of mouse myelin-associated glycoprotein: a novel alternative splicing pattern.

  1989cited by this paper
• Potassium channels from NG108‐15 neuroblastoma‐glioma hybrid cells

  1989cited by this paper

• A personal journey on cracking the genomic codes

  2021cites this paper
• GC-AG Introns Features in Long Non-coding and Protein-Coding Genes Suggest Their Role in Gene Expression Regulation

  2019cites this paper
• Determination of a Comprehensive Alternative Splicing Regulatory Network and Combinatorial Regulation by Key Factors during the Epithelial-to-Mesenchymal Transition

  2016cites this paper
• Correlated Evolution of Nucleotide Positions within Splice Sites in Mammals

  2015cites this paper
• Neural Differentiation Modulates the Vertebrate Brain Specific Splicing Program

  2015cites this paper
• First intron length in mammals is associated with 5’ exon skipping rate

  2015cites this paper
• Aberrant and Alternative Splicing of von Willebrand Factor

  2015cites this paper
• Genome-wide analysis of alternative splicing in Volvox carteri

  2014cites this paper
• OLego: fast and sensitive mapping of spliced mRNA-Seq reads using small seeds

  2013cites this paper
• Voltage-Gated Ion Channel Genes Conservation of Minor Introns in AT-AC Pre-mRNA Splicing Mechanisms and

  2013cites this paper
• An investigation into the mechanism of action of the SMN2 bifunctional oligonucleotide and its application to reverse the RON Δ165 pro-metastatic splicing event

  2012cites this paper
• Cell-specific splicing factors that optimize calcium channel function

  2012cites this paper
• Une nouvelle fonction pour la DEAD-box ARN hélicase p68/DDX5 dans la Dystrophie Myotonique de type 1

  2011cites this paper
• Computational Approaches to the Identification and Characterization of Non-Coding RNA Genes

  2009cites this paper
• Mécanismes moléculaires de la régulation et de la dérégulation de l'épissage alternatif de Tau et cTNT dans la Dystrophie Myotonique de Type 1

  2009cites this paper
• Alternative splicing: current perspectives

  2008cites this paper
• Functional and mechanistic insights from genome-wide studies of splicing regulation in the brain.

  2007cites this paper
• A correlation with exon expression approach to identify cis-regulatory elements for tissue-specific alternative splicing

  2007cites this paper
• The Emergence of Alternative 3′ and 5′ Splice Site Exons from Constitutive Exons

  2007cites this paper
• Refined characterization of the expression and stability of the SMN gene products.

  2007cites this paper
• Differing patterns of selection in alternative and constitutive splice sites.

  2007cites this paper
• Developing global insight into RNA regulation.

  2006cites this paper
• RBPS IN NEURONS AND NEUROLOGIC DISEASE RNA has greater complexity than DNA

  2006cites this paper
• PLP1 alternative splicing in differentiating oligodendrocytes: Characterization of an exonic splicing enhancer

  2006cites this paper
• Comparative evolutionary genomics of the HADH2 gene encoding Aβ-binding alcohol dehydrogenase/17β-hydroxysteroid dehydrogenase type 10 (ABAD/HSD10)

  2006cites this paper
• Alternative splicing in C. elegans.

  2005cites this paper
• Genetic Susceptibility and Animal Modeling of PSP

  2005cites this paper
• How did alternative splicing evolve?

  2004cites this paper
• Feature Selection for Classification of Nucleic Acid Sequences

  2004cites this paper
• Computational comparative analyses of alternative splicing regulation using full-length cDNA of various eukaryotes.

  2004cites this paper
• p59(fyn)-mediated phosphorylation regulates the activity of the tissue-specific splicing factor rSLM-1.

  2004cites this paper
• Prediction and statistical analysis of alternatively spliced exons.

  2003cites this paper
• Neue 5´-Isoformen des Glutamattransporters EAAT2: RNA-Sequenzen und genomische Organisation

  2003cites this paper
• Regulation des alternativen Spleißens von Tau Exon 10 durch Phosphorylierung von Spleißfaktoren

  2003cites this paper
• Impact of alternative initiation, splicing, and termination on the diversity of the mRNA transcripts encoded by the mouse transcriptome.

  2003cites this paper
• Alternative splicing and evolution.

  2003cites this paper
• Alternative splicing during chondrogenesis: Modulation of fibronectin exon EIIIA splicing by SR proteins

  2002cites this paper
• Myelin Oligodendrocyte Gene Polymorphisms and Childhood Multiple Sclerosis

  2002cites this paper
• Alternative splicing: multiple control mechanisms and involvement in human disease.

  2002cites this paper
• Role of Nova-1 in regulating alpha2N, a novel glycine receptor splice variant, in developing spinal cord neurons.

  2002cites this paper
• Alternative Splice Variants of Doublecortin-like Kinase Are Differentially Expressed and Have Different Kinase Activities*

  2002cites this paper
• Identification of Novel Isoforms of the BH3 Domain Protein Bim Which Directly Activate Bax To Trigger Apoptosis

  2002cites this paper
• Analysis of the human TrkB gene genomic organization reveals novel TrkB isoforms, unusual gene length, and splicing mechanism.

  2002cites this paper
• Genome-wide detection of tissue-specific alternative splicing in the human transcriptome.

  2002cites this paper
• Analysis of the role of Caenorhabditis elegans GC-AG introns in regulated splicing.

  2002cites this paper
• A genomic view of alternative splicing

  2002cites this paper
• Computational analysis of candidate intron regulatory elements for tissue-specific alternative pre-mRNA splicing.

  2001cites this paper
• Alternative RNA splicing in the nervous system.

  2001cites this paper
• Multiple cis elements regulate an alternative splicing event at 4 . 1 R pre-mRNA during erythroid differentiation

  2001cites this paper
• Mouse DREAM/calsenilin/KChIP3: gene structure, coding potential, and expression.

  2001cites this paper
• Multiple cis elements regulate an alternative splicing event at 4.1R pre-mRNA during erythroid differentiation.

  2001cites this paper
• B-cell neoplasia associated gene with multiple splicing (BCMS): the candidate B-CLL gene on 13q14 comprises more than 560 kb covering all critical regions.

  2001cites this paper
• Human GC-AG alternative intron isoforms with weak donor sites show enhanced consensus at acceptor exon positions.

  2001cites this paper
• Regulation of alternative splicing of human tau exon 10 by phosphorylation of splicing factors.

  2001cites this paper
• Paraneoplastic neurologic disease antigens: RNA-binding proteins and signaling proteins in neuronal degeneration.

  2001cites this paper
• Neuron-specific Bcl-2 Homology 3 Domain-only Splice Variant of Bak Is Anti-apoptotic in Neurons, but Pro-apoptotic in Non-neuronal Cells*

  2001cites this paper
• The splice of life: Alternative splicing and neurological disease

  2001cites this paper
• Characterization of ATM mutations in 41 Nordic families with Ataxia Telangiectasia

  2000cites this paper
• Genomic sequence, splicing, and gene annotation.

  2000cites this paper
• The genomic structure of human olfactory receptor genes.

  2000cites this paper
• What the evolution of the amyloid protein precursor supergene family tells us about its function.

  2000cites this paper
• Complex Regulation of Tau Exon 10, Whose Missplicing Causes Frontotemporal Dementia

  2000cites this paper
• An Intronic Downstream Enhancer Promotes 3′ Splice Site Usage of a Neural Cell-specific Exon*

  2000cites this paper
• ASDB: database of alternatively spliced genes

  2000cites this paper
• Misregulation of pre-mRNA splicing that causes human diseases

  2000influential citation
• An Alternative-Exon Database and Its Statistical Analysis

  2000cites this paper
• Distinct expression of splice variants of neuronal nitric oxide synthase in the human gastrointestinal tract.

  2000cites this paper
• A Multi-agent System Simulating Human Splice Site Recognition

  1999cites this paper
• Alternative Splicing Determines the Intracellular Localization of the Novel Nuclear Protein Nop30 and Its Interaction with the Splicing Factor SRp30c*

  1999cites this paper
• ASDB: database of alternatively spliced genes

  1999cites this paper
• Control of 3' splice site choice in vivo by ASF/SF2 and hnRNP A1.

  1999cites this paper
• The interaction and colocalization of Sam68 with the splicing-associated factor YT521-B in nuclear dots is regulated by the Src family kinase p59(fyn).

  1999cites this paper
• Activity‐dependent regulation of alternative splicing patterns in the rat brain

  1999cites this paper
• Krainer Voltage-Gated Ion Channel Genes Conservation of Minor Introns in ATAC Pre-mRNA Splicing Mechanisms and

  1999cites this paper
• Changes in pre-mRNA splicing factors during neural differentiation in P19 embryonal carcinoma cells.

  1999cites this paper
• The RNA of the glutamate transporter EAAT2 is variably spliced in amyotrophic lateral sclerosis and normal individuals.

  1999cites this paper
• AT-AC Pre-mRNA Splicing Mechanisms and Conservation of Minor Introns in Voltage-Gated Ion Channel Genes

  1999cites this paper
• The in vivo minigene approach to analyze tissue-specific splicing.

  1999cites this paper
• Regulation of the neuron-specific exon of clathrin light chain B.

  1999cites this paper
• Neuron-specific splicing of zinc finger transcription factor REST/NRSF/XBR is frequent in neuroblastomas and conserved in human, mouse and rat.

  1999cites this paper
• The Cellular Localization of the Murine Serine/Arginine-rich Protein Kinase CLK2 Is Regulated by Serine 141 Autophosphorylation*

  1998cites this paper
• Adaptive computation and machine learning

  1998cites this paper
• Splicing of a Regulated Exon Reveals Additional Complexity in the Axonal Microtubule‐Associated Protein Tau

  1998cites this paper
• Molecular cloning of a novel alternatively spliced nuclear protein 1

  1998cites this paper
• Human transformer-2-beta gene (SFRS10): complete nucleotide sequence, chromosomal localization, and generation of a tissue-specific isoform.

  1998influential citation
• Structure and alternative splicing of the ketohexokinase gene.

  1998cites this paper
• Generation of alternative Ultrabithorax isoforms and stepwise removal of a large intron by resplicing at exon-exon junctions.

  1998cites this paper
• Regulation of the sarco/endoplasmic reticulum Ca(2+)-ATPase (SERCA) 2 gene transcript in neuronal cells.

  1998cites this paper
• Statistical features of human exons and their flanking regions.

  1998cites this paper
• Association of the neuron-specific RNA binding domain-containing protein ELAV with the coiled body inDrosophila neurons

  1997cites this paper
• In situ hybridization localization of the GABAA receptor beta 2S- and beta 2L-subunit transcripts reveals cell-specific splicing of alternate cassette exons.

  1997cites this paper
• Regulated expression and RNA processing of transcripts from the Srp20 splicing factor gene during the cell cycle

  1997cites this paper
• Structural, functional, and protein binding analyses of bovine papillomavirus type 1 exonic splicing enhancers

  1997cites this paper
• A unique intronic splicing enhancer controls the inclusion of the agrin Y exon.

  1997cites this paper
• Molecular cloning of a novel alternatively spliced nuclear protein.

  1997cites this paper
• Molecular Cloning of htra2-beta-1 and htra2-beta-2, Two Human Homologs of tra-2 Generated by Alternative Splicing

  1997cites this paper
• Myelin/Oligodendrocyte Glycoprotein

  1997cites this paper
• The neuronal RNA binding protein Nova-1 recognizes specific RNA targets in vitro and in vivo

  1997cites this paper
• Natural base-pairing interactions between 5' splice site and branch site sequences affect mammalian 5' splice site selection.

  1997cites this paper
• Zebrafish Pax9 Encodes Two Proteins with Distinct C-terminal Transactivating Domains of Different Potency Negatively Regulated by Adjacent N-terminal Sequences*

  1996cites this paper