Low-molecular-weight protamine-modified PLGA nanoparticles for overcoming drug-resistant breast cancer.

No abstract is available for this paper.

• Publication year

  2014

• Venue

  Journal of Controlled Release

• Publication date

  2014-10-28

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1016/j.jconrel.2014.06.051PMID 25003794
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Estimation of rat mammary tumor volume using caliper and ultrasonography measurements

  2013cited by this paper
• Cell-penetrating albumin conjugates for enhanced doxorubicin delivery

  2013cited by this paper
• Overcoming multidrug resistance of cancer cells by direct intranuclear drug delivery using TAT-conjugated mesoporous silica nanoparticles.

  2013cited by this paper
• Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer

  2013cited by this paper
• Endocytosis, intracellular traffic and fate of cell penetrating peptide based conjugates and nanoparticles.

  2013cited by this paper
• The use of low molecular weight protamine chemical chimera to enhance monomeric insulin intestinal absorption.

  2013cited by this paper
• Improving Drug Uptake and Penetration into Tumors: Current and Forthcoming Opportunities

  2013cited by this paper
• Curb challenges of the "Trojan Horse" approach: smart strategies in achieving effective yet safe cell-penetrating peptide-based drug delivery.

  2013cited by this paper
• Change Trends of Organ Weight Background Data in Sprague Dawley Rats at Different Ages

  2013cited by this paper
• Skin-permeable quaternary nanoparticles with layer-by-layer structure enabling improved gene delivery

  2012cited by this paper
• Nuclear-targeted drug delivery of TAT peptide-conjugated monodisperse mesoporous silica nanoparticles.

  2012cited by this paper
• TAT-modified nanosilver for combating multidrug-resistant cancer.

  2012cited by this paper
• Penetration of anticancer drugs through tumour tissue as a function of cellular packing density and interstitial fluid pressure and its modification by bortezomib

  2012cited by this paper
• Traceable multifunctional micellar nanocarriers for cancer-targeted co-delivery of MDR-1 siRNA and doxorubicin.

  2011cited by this paper
• Hypoxia-mediated drug resistance: novel insights on the functional interaction of HIFs and cell death pathways.

  2011cited by this paper
• Global cancer statistics

  2011cited by this paper
• Synthetic skin-permeable proteins enabling needleless immunization.

  2010cited by this paper
• Phage Display–Derived Peptides for Osteosarcoma Imaging

  2010cited by this paper
• Glycosaminoglycans as potential regulators of osteoprotegerin therapeutic activity in osteosarcoma.

  2009cited by this paper
• Charge‐Reversal Drug Conjugate for Targeted Cancer Cell Nuclear Drug Delivery

  2009cited by this paper
• Anti-apoptotic mechanisms of drug resistance in cancer.

  2009cited by this paper
• Drug resistance and the solid tumor microenvironment.

  2007cited by this paper
• Drug penetration in solid tumours

  2006cited by this paper
• Targeting multidrug resistance in cancer

  2006cited by this paper
• Nontoxic membrane translocation peptide from protamine, low molecular weight protamine (LMWP), for enhanced intracellular protein delivery: in vitro and in vivo study

  2005cited by this paper
• Micellar carriers based on block copolymers of poly(epsilon-caprolactone) and poly(ethylene glycol) for doxorubicin delivery.

  2004cited by this paper
• Micellar carriers based on block copolymers of poly(ε-caprolactone) and poly(ethylene glycol) for doxorubicin delivery

  2004cited by this paper
• High interstitial fluid pressure — an obstacle in cancer therapy

  2004cited by this paper
• A Less Toxic Heparin Antagonist—Low Molecular Weight Protamine

  2004cited by this paper
• Physico-chemical stability of colloidal lipid particles.

  2003cited by this paper
• Tumor hypoxia: A target for selective cancer therapy

  2003cited by this paper
• Heparan sulfate proteoglycans as regulators of fibroblast growth factor-2 receptor binding in breast carcinomas.

  2002cited by this paper
• Quantitation of the tumor-targeting properties of antibody fragments conjugated to cell-permeating HIV-1 TAT peptides.

  2002cited by this paper
• Limited penetration of anticancer drugs through tumor tissue: a potential cause of resistance of solid tumors to chemotherapy.

  2002cited by this paper
• Glypican-1 is overexpressed in human breast cancer and modulates the mitogenic effects of multiple heparin-binding growth factors in breast cancer cells.

  2001cited by this paper
• Low molecular weight protamine as nontoxic heparin/low molecular weight heparin antidote (III): Preliminary in vivo evaluation of efficacy and toxicity using a canine model

  2001cited by this paper
• Low molecular weight protamine (LMWP) as nontoxic heparin/low molecular weight heparin antidote (I): Preparation and characterization

  2001cited by this paper
• Low molecular weight protamine (LMWP) as nontoxic heparin/low molecular weight heparin antidote (II): In vitro evaluation of efficacy and toxicity

  2001cited by this paper
• Doxorubicin-loaded poly(ethylene glycol)-poly(beta-benzyl-L-aspartate) copolymer micelles: their pharmaceutical characteristics and biological significance.

  2000cited by this paper
• Nuclear delivery of doxorubicin via folate-targeted liposomes with bypass of multidrug-resistance efflux pump.

  2000cited by this paper
• The cell-surface heparan sulfate proteoglycan glypican-1 regulates growth factor action in pancreatic carcinoma cells and is overexpressed in human pancreatic cancer.

  1998cited by this paper

• Comparison of subcellular trafficking of the low molecular weight protamine (LMWP) fragment in tumor and non-tumor cells

  2026cites this paper
• Optimization of cationic functionalized nanoparticles for brain targeting: in vivo evaluation.

  2025cites this paper
• Development of an Innovative Nanosystem Based on Functionalized Albumin and Oxidized Gellan for the Synergistic Delivery of Curcumin and Temozolomide in the Treatment of Brain Cancer

  2025cites this paper
• Effect of TIMPs and their minimally engineered variants in blocking invasion and migration of brain cancer cells

  2025cites this paper
• Effect of TIMPs and Their Minimally Engineered Variants in Blocking Invasion and Migration of Brain Cancer Cells

  2024cites this paper
• Recent advances in the development of poly(ester amide)s-based carriers for drug delivery

  2024cites this paper
• Cationic anticancer peptide L-K6-modified and doxorubicin-loaded mesoporous silica nanoparticles reverse multidrug resistance of breast cancer

  2024cites this paper
• Multibarrier-penetrating drug delivery systems for deep tumor therapy based on synergistic penetration strategy.

  2024cites this paper
• Self-assembled redox-responsive BRD4 siRNA nanoparticles: fomulation and its in vitro delivery in gastric cancer cells

  2024cites this paper
• Harnessing the Potential of PLGA Nanoparticles for Enhanced Bone Regeneration

  2024cites this paper
• Bromocriptine mesylate-loaded nanoparticles co-modified with low molecular weight protamine and lactoferrin for enhanced nose-to-brain delivery in Parkinson's disease treatment.

  2024cites this paper
• Designed Cell-Penetrating Peptide Constructs for Inhibition of Pathogenic Protein Self-Assembly

  2024cites this paper
• Fine-tuning of liposome integrity for differentiated transcytosis and enhanced antitumor efficacy.

  2024cites this paper
• Cell penetrating peptides: Highlighting points in cancer therapy

  2023influential citation
• Recent Advancements and Strategies for Overcoming the Blood–Brain Barrier Using Albumin-Based Drug Delivery Systems to Treat Brain Cancer, with a Focus on Glioblastoma

  2023cites this paper
• Design and characterization of antithrombotic ClEKnsTy-Au nanoparticles as diagnostic and therapeutic reagents.

  2023cites this paper
• pH-responsive PLGA/gelatin porous microspheres containing paclitaxel used for inhibition of cancer cell proliferation

  2023cites this paper
• Targeted therapy of breast tumor by PLGA-based nanostructures: The versatile function in doxorubicin delivery.

  2023cites this paper
• Ocular Delivery of Therapeutic Agents by Cell-Penetrating Peptides

  2023cites this paper
• Advances in nanobiotechnology-propelled multidrug resistance circumvention of cancer.

  2022cites this paper
• Targeted Nanoparticles for the Binding of Injured Vascular Endothelium after Percutaneous Coronary Intervention

  2022cites this paper
• Recent advances in anti-multidrug resistance for nano-drug delivery system

  2022cites this paper
• Comparative Proteomic Analysis of Drug Trichosanthin Addition to BeWo Cell Line

  2022cites this paper
• Transcytosis mechanisms of cell‐penetrating peptides: Cation‐independent CC12 and cationic penetratin

  2022cites this paper
• New generation of cell‐penetrating peptides: Functionality and potential clinical application

  2021cites this paper
• Redefining the importance of polylactide-co-glycolide acid (PLGA) in drug delivery.

  2021cites this paper
• Recent advances in PLGA based nanocarriers for drug delivery system: a state of the art review

  2021cites this paper
• p28-functionalized PLGA nanoparticles loaded with gefitinib reduce tumor burden and metastases formation on lung cancer.

  2021cites this paper
• State of Art: Cell Penetration and Cell-Penetrating Peptides and Proteins

  2021cites this paper
• Cytotoxicity of targeted PLGA nanoparticles: a systematic review

  2021cites this paper
• Multifunctional nanoplatforms co-delivering combinatorial dual-drug for eliminating cancer multidrug resistance

  2021cites this paper
• Drug Resistance in Metastatic Breast Cancer: Tumor Targeted Nanomedicine to the Rescue

  2021cites this paper
• Cyclodextrin-Based Hybrid Polymeric Complex to Overcome Dual Drug Resistance Mechanisms for Cancer Therapy

  2021cites this paper
• Peptides-based therapy and diagnosis. Strategies for non-invasive therapies in cancer

  2021cites this paper
• Peptides, proteins and nanotechnology: a promising synergy for breast cancer targeting and treatment

  2020cites this paper
• Novel nanotechnology approaches for diagnosis and therapy of breast, ovarian and cervical cancer in female: A review

  2020cites this paper
• New and novel approaches for enhancing the oral absorption and bioavailability of protein and peptides therapeutics.

  2020cites this paper
• Nanotechnology-based targeted drug delivery systems and drug resistance in colorectal cancer

  2020cites this paper
• Possible contribution of sialic acid to the enhanced tumor targeting efficiency of nanoparticles engineered with doxorubicin

  2020cites this paper
• Core-shell lipid-polymer nanoparticles as a promising ocular drug delivery system to treat glaucoma

  2020cites this paper
• Pluronic micelles with suppressing doxorubicin efflux and detoxification for efficiently reversing breast cancer resistance.

  2020cites this paper
• Cell-Penetrating Peptides in Oncologic Pharmacotherapy: A Review.

  2020cites this paper
• Transferrin-conjugated doxorubicin-loaded PLGA nanoparticles with pH-responsive behavior: a synergistic approach for cancer therapy

  2020cites this paper
• Doxorubicin derivative loaded acetal-PEG-PCCL micelles for overcoming multidrug resistance in MCF-7/ADR cells

  2019cites this paper
• ‘Dendrimer‐Cationized‐Albumin’ encrusted polymeric nanoparticle improves BBB penetration and anticancer activity of doxorubicin

  2019cites this paper
• PLGA scaffolds: building blocks for new age therapeutics

  2019cites this paper
• pH-sensitive free AgNPs composite and nanocomposite beads based on starch as drug delivery systems

  2019cites this paper
• Recent Progress in the Development of Poly(lactic-co-glycolic acid)-Based Nanostructures for Cancer Imaging and Therapy

  2019influential citation
• The role of NIR fluorescence in MDR cancer treatment: From targeted imaging to phototherapy.

  2019cites this paper
• Functionalized polymers for drug/gene-delivery applications

  2019cites this paper
• The current role of cell-penetrating peptides ( CPPs ) in cancer therapy

  2019cites this paper
• Neutrophils, as “Trojan horses”, participate in the delivery of therapeutical PLGA nanoparticles into a tumor based on the chemotactic effect

  2019cites this paper
• Cell Penetrating Peptides as Molecular Carriers for Anti-Cancer Agents

  2018cites this paper
• Poly(lactic-co-glycolic acid): The most ardent and flexible candidate in biomedicine!

  2018cites this paper
• Temporary suppression the sequestrated function of host macrophages for better nanoparticles tumor delivery

  2018cites this paper
• Reduction/photo dual-responsive polymeric prodrug nanoparticles for programmed siRNA and doxorubicin delivery.

  2018cites this paper
• Targeting death receptors for drug-resistant cancer therapy: Codelivery of pTRAIL and monensin using dual-targeting and stimuli-responsive self-assembling nanocomposites.

  2018cites this paper
• Liposomal Codelivery of Doxorubicin and Andrographolide Inhibits Breast Cancer Growth and Metastasis.

  2018cites this paper
• Codelivery of dihydroartemisinin and doxorubicin in mannosylated liposomes for drug-resistant colon cancer therapy

  2017cites this paper
• The Route of Nanomaterials Entering Brain

  2017cites this paper
• Targeting nanocarriers containing antisense oligonucleotides to cancer cell

  2017cites this paper
• Co-Delivery of Trichosanthin and Albendazole by Nano-Self-Assembly for Overcoming Tumor Multidrug-Resistance and Metastasis.

  2017cites this paper
• Intrinsic radiolabeling of Titanium-45 using mesoporous silica nanoparticles

  2017cites this paper
• Glioma Dual-Targeting Nanohybrid Protein Toxin Constructed by Intein-Mediated Site-Specific Ligation for Multistage Booster Delivery

  2017cites this paper
• Anti-angiogenesis through noninvasive to minimally invasive intraocular delivery of the peptide CC12 identified by in vivo-directed evolution.

  2017cites this paper
• Targeted nanomedicine for cancer therapeutics: Towards precision medicine overcoming drug resistance.

  2017cites this paper
• MDR in cancer: Addressing the underlying cellular alterations with the use of nanocarriers.

  2017cites this paper
• A mannosylated PEI–CPP hybrid for TRAIL gene targeting delivery for colorectal cancer therapy

  2017cites this paper
• Tandem Peptide Based on Structural Modification of Poly-Arginine for Enhancing Tumor Targeting Efficiency and Therapeutic Effect.

  2017cites this paper
• The Development and Achievement of Polymeric Nanoparticles for Cancer Drug Treatment

  2017cites this paper
• A facile approach to functionalizing cell membrane‐coated nanoparticles with neurotoxin‐derived peptide for brain‐targeted drug delivery

  2017cites this paper
• Multifunctional nanoplatform for enhanced photodynamic cancer therapy and magnetic resonance imaging.

  2017cites this paper
• Heparin-Regulated Prodrug-Type Macromolecular Theranostic Systems for Cancer Therapy

  2017cites this paper
• Development of a new type of multifunctional fucoidan-based nanoparticles for anticancer drug delivery.

  2017cites this paper
• The achievement of ligand-functionalized organic/polymeric nanoparticles for treating multidrug resistant cancer

  2017cites this paper
• Intein-mediated site-specific synthesis of tumor-targeting protein delivery system: Turning PEG dilemma into prodrug-like feature.

  2017cites this paper
• Nanotechnology-based combination therapy for overcoming multidrug-resistant cancer

  2017cites this paper
• The Current Role of Cell-Penetrating Peptides in Cancer Therapy.

  2017cites this paper
• Preparation of poly(lactic-co-glycolic acid) and chitosan composite nanocarriers via electrostatic self assembly for oral delivery of insulin.

  2017cites this paper
• Prodrug-Like, PEGylated Protein Toxin Trichosanthin for Reversal of Chemoresistance.

  2017cites this paper
• Liquid formulation containing doxorubicin-loaded lipid-core nanocapsules: Cytotoxicity in human breast cancer cell line and in vitro uptake mechanism.

  2017cites this paper
• Tumour microenvironment-responsive lipoic acid nanoparticles for targeted delivery of docetaxel to lung cancer

  2016cites this paper
• Evaluation of β-cyclodextrin-modified gemini surfactant-based delivery systems in melanoma models

  2016cites this paper
• Nanomedicine strategy for optimizing delivery to outer hair cells by surface-modified poly(lactic/glycolic acid) nanoparticles with hydrophilic molecules

  2016cites this paper
• Design and evaluation of a novel potential carrier for a hydrophilic antitumor drug: Auricularia auricular polysaccharide-chitosan nanoparticles as a delivery system for doxorubicin hydrochloride.

  2016cites this paper
• Polymer-Based Novel Lung Targeted Delivery Systems.

  2016cites this paper
• Enhanced and Extended Anti-Hypertensive Effect of VP5 Nanoparticles

  2016cites this paper
• Nuclear-targeting TAT-PEG-Asp8-doxorubicin polymeric nanoassembly to overcome drug-resistant colon cancer

  2016cites this paper
• Dual Receptor Recognizing Cell Penetrating Peptide for Selective Targeting, Efficient Intratumoral Diffusion and Synthesized Anti-Glioma Therapy

  2016cites this paper
• Cell penetrating peptide-modified poly(lactic-co-glycolic acid) nanoparticles with enhanced cell internalization.

  2016cites this paper
• Blood-Brain-Barrier-Penetrating Albumin Nanoparticles for Biomimetic Drug Delivery via Albumin-Binding Protein Pathways for Antiglioma Therapy.

  2016cites this paper
• Fabrication of novel core–shell PLGA and alginate fiber for dual‐drug delivery system

  2016cites this paper
• A Prodrug-type, MMP-2-targeting Nanoprobe for Tumor Detection and Imaging

  2015cites this paper
• Nanoparticle-Mediated Delivery of Therapeutic Drugs

  2015cites this paper
• Methotrexate loaded chitosan nanoparticles: Preparation, radiolabeling and in vitro evaluation for breast cancer diagnosis

  2015cites this paper
• Twin-Arginine Translocation Peptide Conjugated Epirubicin-Loaded Nanoparticles for Enhanced Tumor Penetrating and Targeting.

  2015cites this paper
• Preparation and evaluation of lipid emulsified docetaxel‐loaded nanoparticles

  2015cites this paper
• N-trimethyl chitosan chloride-coated PLGA nanoparticles overcoming multiple barriers to oral insulin absorption.

  2015cites this paper
• 15 years of ATTEMPTS: a macromolecular drug delivery system based on the CPP-mediated intracellular drug delivery and antibody targeting.

  2015cites this paper
• Enzymatically and reductively degradable α-amino acid-based poly(ester amide)s: synthesis, cell compatibility, and intracellular anticancer drug delivery.

  2015cites this paper