Identification of cIAP1 as a candidate target gene within an amplicon at 11q22 in esophageal squamous cell carcinomas.

No abstract is available for this paper.

• Publication year

  2001

• Venue

  Cancer Research

• Publication date

  2001-09-15

• Fields of study

  Biology, Medicine

• Identifiers
  PMID 11559525
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Clinocopathologic significance of laminin-5 gamma2 chain expression in squamous cell carcinoma of the tongue: immunohistochemical analysis of 67 lesions.

  2000cited by this paper
• Quantitative mapping of amplicon structure by array CGH identifies CYP24 as a candidate oncogene

  2000cited by this paper
• Identification of a novel gene, GASC1, within an amplicon at 9p23-24 frequently detected in esophageal cancer cell lines.

  2000cited by this paper
• Nonrandom Chromosomal Imbalances in Esophageal Squamous Cell Carcinoma Cell Lines: Possible Involvement of the ATF3 and CENPF Genes in the 1q32 Amplicon

  2000cited by this paper
• Amplification and overexpression of TGIF2, a novel homeobox gene of the TALE superclass, in ovarian cancer cell lines.

  2000cited by this paper
• Increased expression of collagenase-3 (MMP-13) and MT1-MMP in oesophageal cancer is related to cancer aggressiveness

  2000cited by this paper
• CD44 is a potential target of amplification within the 11p13 amplicon detected in gastric cancer cell lines

  2000cited by this paper
• Expression and prognostic significance of IAP-family genes in human cancers and myeloid leukemias.

  2000cited by this paper
• Oncogene amplification in solid tumors.

  1999cited by this paper
• API1-MALT1-MLT is involved in mucosa-associated lymphoid tissue lymphoma with t(11;18)(q21;q21)

  1999cited by this paper
• A novel gene, MALT1 at 18q21, is involved in t(11;18) (q21;q21) found in low-grade B-cell lymphoma of mucosa-associated lymphoid tissue

  1999cited by this paper
• DNA copy number losses in human neoplasms.

  1999cited by this paper
• Comparative genomic hybridization of squamous cell carcinoma of the esophagus: The possible involvement of the DP1 gene in the 13q34 amplicon

  1999cited by this paper
• The p16-cyclin D1/CDK4-pRb pathway and clinical outcome in epithelial ovarian cancer.

  1999cited by this paper
• The apoptosis inhibitor gene API2 and a novel 18q gene, MLT, are recurrently rearranged in the t(11;18)(q21;q21) associated with mucosa-associated lymphoid tissue lymphomas.

  1999cited by this paper
• Molecular cytogenetic fingerprinting of esophageal squamous cell carcinoma by comparative genomic hybridization reveals a consistent pattern of chromosomal alterations

  1999cited by this paper
• Evaluation of the clonal relationship between primary and metastatic renal cell carcinoma by comparative genomic hybridization.

  1999cited by this paper
• Comparative genomic hybridization and chromosomal instability in solid tumours

  1999cited by this paper
• Clinicopathologic significance of laminin‐5 γ2 chain expression in squamous cell carcinoma of the tongue

  1999cited by this paper
• IAPs block apoptotic events induced by caspase‐8 and cytochrome c by direct inhibition of distinct caspases

  1998cited by this paper
• Comparative genomic hybridization reveals frequent chromosome 13q and 4q losses in renal carcinomas with sarcomatoid transformation

  1998cited by this paper
• NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation.

  1998cited by this paper
• Consistent genetic alterations in xenografts of proximal stomach and gastro-esophageal junction adenocarcinomas.

  1998cited by this paper
• The inhibitors of apoptosis (IAPs) and their emerging role in cancer

  1998influential reference
• Selective activation of JNK1 is necessary for the anti-apoptotic activity of hILP.

  1998cited by this paper
• Positional cloning of ZNF217 and NABC1: genes amplified at 20q13.2 and overexpressed in breast carcinoma.

  1998cited by this paper
• BCL2 overexpression associated with chromosomal amplification in diffuse large B-cell lymphoma.

  1997cited by this paper
• A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma

  1997cited by this paper
• X-linked IAP is a direct inhibitor of cell-death proteases

  1997cited by this paper
• Extensive genomic abnormalities in childhood medulloblastoma by comparative genomic hybridization.

  1997cited by this paper
• The c‐IAP‐1 and c‐IAP‐2 proteins are direct inhibitors of specific caspases

  1997cited by this paper
• Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes

  1996cited by this paper
• Clinically distinct subgroups of glioblastoma multiforme studied by comparative genomic hybridization.

  1996cited by this paper
• Cyclin D1 amplification as a new predictive classification for squamous cell carcinoma of the esophagus, adding gene information.

  1996cited by this paper
• Clonal origin of Philadelphia chromosome negative cells with trisomy 8 appearing during the course of alpha-interferon therapy for Ph positive chronic myelocytic leukemia.

  1995cited by this paper
• The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins.

  1995cited by this paper
• Amplification and expression of the human cyclin D gene in esophageal cancer.

  1992cited by this paper
• Characterization of 21 newly established esophageal cancer cell lines

  1992cited by this paper
• Physical Ordering of Three Polymorphic DNA Markers Spanning the Regions Containing a Tumor Suppressor Gene of Renal Cell Carcinoma by Three‐color Fluorescent in situ Hybridization

  1992cited by this paper
• Detection of mRNAs encoding collagenase I and stromelysin 2 in carcinomas of the head and neck by in situ hybridization.

  1991cited by this paper
• Amplification of the EGF receptor and c‐myc genes in human esophageal cancers

  1988cited by this paper
• Expression in non-Hodgkin's lymphoma of the bcl-2 protein associated with the t(14;18) chromosomal translocation.

  1988cited by this paper

• Complex IIa formation and ABC transporters determine sensitivity of OSCC to Smac mimetics

  2024cites this paper
• Tumour response to hypoxia: understanding the hypoxic tumour microenvironment to improve treatment outcome in solid tumours

  2024cites this paper
• YAP1/TAZ Mediates Rumen Epithelial Cell Proliferation but Not Short-Chain Fatty Acid Metabolism In Vitro

  2024cites this paper
• Drug Discovery Approaches to Target E3 Ligases

  2024cites this paper
• LLPS of SQSTM1/p62 and NBR1 as outcomes of lysosomal stress response limits cancer cell metastasis

  2023cites this paper
• Prognostic Significance of the BIRC2-BIRC3 Gene Signature in Head and Neck Squamous Cell Carcinoma

  2022cites this paper
• Potential for reversing miR-634-mediated cytoprotective processes to improve efficacy of chemotherapy against oral squamous cell carcinoma

  2022cites this paper
• Relationship between Yes-Associated Protein 1 and Prognosis of Digestive System Neoplasm: Quantitative Analysis and Bioinformatics Analysis Based on 4023 Patients

  2022cites this paper
• Snail Promotes Cancer Cell Proliferation via Its Interaction with the BIRC3

  2022cites this paper
• Targeting YAP1/TAZ in nonsmall‐cell lung carcinoma: From molecular mechanisms to precision medicine

  2022cites this paper
• Estrogen Receptor-α Targeting: PROTACs, SNIPERs, Peptide-PROTACs, Antibody Conjugated PROTACs and SNIPERs

  2022cites this paper
• Loss of cIAP1 in Endothelial Cells Limits Metastatic Extravasation through Tumor-Derived Lymphotoxin Alpha

  2021cites this paper
• The multiple roles of the IAP super-family in cancer.

  2020cites this paper
• CircRNA hsa_circ_0004771 promotes esophageal squamous cell cancer progression via miR-339-5p/CDC25A axis.

  2020cites this paper
• ANTP‐SmacN7 fusion peptide‐induced radiosensitization in A549 cells and its potential mechanisms

  2020cites this paper
• Targeting triple-negative breast cancers with the Smac-mimetic birinapant

  2020influential citation
• SNIPERs-Hijacking IAP activity to induce protein degradation.

  2019cites this paper
• Dysregulation of the Hippo pathway signaling in aging and cancer

  2019cites this paper
• Tumor cell-derived lymphotoxin alpha triggers metastatic extravasation through TNFRs/cIAP1

  2019cites this paper
• Mechanotransduction and Cytoskeleton Remodeling Shaping YAP1 in Gastric Tumorigenesis

  2019cites this paper
• Different Degradation Mechanisms of Inhibitor of Apoptosis Proteins (IAPs) by the Specific and Nongenetic IAP-Dependent Protein Eraser (SNIPER).

  2019cites this paper
• LCL161, a SMAC-mimetic, Preferentially Radiosensitizes Human Papillomavirus–negative Head and Neck Squamous Cell Carcinoma

  2019cites this paper
• PKCι and YAP1 are crucial in promoting pancreatic tumorigenesis

  2018cites this paper
• YAP/TAZ Activation as a Target for Treating Metastatic Cancer

  2018cites this paper
• Derivatization of inhibitor of apoptosis protein (IAP) ligands yields improved inducers of estrogen receptor α degradation

  2018cites this paper
• Tumor Necrosis Factor Receptor Superfamily in T Cell Priming and Effector Function.

  2018cites this paper
• The effects of NF-κB signal pathway on the process of anastomotic stricture after the radical resection of esophageal carcinoma

  2018cites this paper
• A landscape of synthetic viable interactions in cancer

  2017cites this paper
• Molecular mechanisms underlying the α-tomatine-directed apoptosis in human malignant glioblastoma cell lines A172 and U-118 MG.

  2017cites this paper
• In Vivo Knockdown of Pathogenic Proteins via Specific and Nongenetic Inhibitor of Apoptosis Protein (IAP)-dependent Protein Erasers (SNIPERs)*

  2017cites this paper
• Recurring Amplification at 11q22.1-q22.2 Locus Plays an Important Role in Lymph Node Metastasis and Radioresistance in OSCC

  2017cites this paper
• Regulating the balance between necroptosis, apoptosis and inflammation by inhibitors of apoptosis proteins

  2017cites this paper
• Effects of bufalin on the mTOR/p70S6K pathway and apoptosis in esophageal squamous cell carcinoma in nude mice

  2017cites this paper
• Emerging role of Hippo pathway in gastric and other gastrointestinal cancers.

  2016cites this paper
• Genomic insights into head and neck cancer

  2016cites this paper
• Protein Knockdown Technology: Application of Ubiquitin Ligase to Cancer Therapy.

  2016cites this paper
• Yes-associated protein in the liver: Regulation of hepatic development, repair, cell fate determination and tumorigenesis.

  2015cites this paper
• YAPing Hippo Forecasts a New Target for Lung Cancer Prevention and Treatment.

  2015cites this paper
• Birc2-Amplifikationen bei Plattenepithelkarzinomen des Kopf-Hals-Bereiches und deren Einfluss auf den Tumorphänotyp und die Patientenprognose

  2015cites this paper
• Schädigung des Lungenepithels durch Zink- und Kadmiumchlorid - Eine Analyse am in-vitro-Modell der alveolar-kapillären Barriere

  2015cites this paper
• miR-544a induces epithelial-mesenchymal transition through the activation of WNT signaling pathway in gastric cancer.

  2015cites this paper
• The role of epithelial cell de-differentiation in the context of improved chemotherapy applied to pancreatic cancer

  2015cites this paper
• IAP antagonization promotes inflammatory destruction of vasculature endothelium and inhibits tumor growth

  2015cites this paper
• IAP Family of Proteins as Therapeutic Targets for Acute Myeloid Leukemia

  2015cites this paper
• shRNA Depletion of cIAP1 Sensitizes Human Ovarian Cancer Cells to Anticancer Agent-Induced Apoptosis

  2015cites this paper
• Activation of Yes-Associated Protein in Low-Grade Meningiomas Is Regulated by Merlin, Cell Density, and Extracellular Matrix Stiffness

  2015cites this paper
• Survivin expression correlates with nodal metastasis in T1–T2 squamous cell carcinoma of the tongue

  2015cites this paper
• Variation in Apoptotic Gene Expression in Cervical Cancer Through Oligonucleotide Microarray Profiling

  2015cites this paper
• Engineered Versions of Granzyme B and Angiogenin Overcome Intrinsic Resistance to Apoptosis Mediated by Human Cytolytic Fusion Proteins

  2015cites this paper
• Novel Role of CHK2 in the Intrinsic and Extrinsic Apoptosis Pathway

  2014cites this paper
• Cell Death and Cancer

  2014cites this paper
• YAP1 acts as oncogenic target of 11q22 amplification in multiple cancer subtypes

  2014cites this paper
• Small Molecule Therapeutics Birinapant ( TL 32711 ) , a Bivalent SMAC Mimetic , Targets TRAF 2-Associated cIAPs , Abrogates TNF-Induced NFk B Activation , and Is Active in Patient-Derived Xenograft Models

  2014cites this paper
• Analyse des propriétés oncogéniques de cIAP1 : contribution de ses partenaires cdc42 et E2F1

  2014cites this paper
• Small-molecule SMAC mimetics as new cancer therapeutics.

  2014cites this paper
• Birinapant (TL32711), a Bivalent SMAC Mimetic, Targets TRAF2-Associated cIAPs, Abrogates TNF-Induced NF-κB Activation, and Is Active in Patient-Derived Xenograft Models

  2014cites this paper
• The Hippo Kinase Pathway: a master regulator of proliferation, development and differentiation

  2014cites this paper
• Clinical Impact of Predicting CCND1 Amplification Using Plasma DNA in Superficial Esophageal Squamous Cell Carcinoma

  2014cites this paper
• Apollon modulates chemosensitivity in human esophageal squamous cell carcinoma

  2014cites this paper
• IAP Proteins and Their Therapeutic Potential

  2014cites this paper
• Antagonists of IAP proteins as cancer therapeutics.

  2013cites this paper
• The dual functions of YAP-1 to promote and inhibit cell growth in human malignancy

  2013cites this paper
• IAP proteins as targets for drug development in oncology

  2013cites this paper
• Drug Resistance and Molecular Cancer Therapy: Apoptosis Versus Autophagy

  2013cites this paper
• cAMP/PKA signalling reinforces the LATS–YAP pathway to fully suppress YAP in response to actin cytoskeletal changes

  2013cites this paper
• Tissue biomarkers as prognostic variables of cervical cancer.

  2013cites this paper
• SMAC IAP Addiction in Cancer

  2013cites this paper
• Hippo and Mouse Models for Cancer

  2013cites this paper
• Inhibitor of Apoptosis Proteins: Promising Targets for Cancer Therapy

  2013cites this paper
• IAPs on the move: role of inhibitors of apoptosis proteins in cell migration

  2013cites this paper
• Cell death and life in cancer: mathematical modeling of cell fate decisions.

  2013cites this paper
• Nuclear expression of Yes-associated protein 1 correlates with poor prognosis in intestinal type gastric cancer.

  2012cites this paper
• The Opposing Roles of Cellular Inhibitor of Apoptosis Proteins in Cancer

  2012cites this paper
• Expression of Yes-associated protein modulates Survivin expression in primary liver malignancies.

  2012cites this paper
• Identification of cyclin B1 and Sec62 as biomarkers for recurrence in patients with HBV-related hepatocellular carcinoma after surgical resection

  2012cites this paper
• Yes-Associated Protein Regulates the Hepatic Response After Bile Duct Ligation

  2012cites this paper
• Exploiting inhibitor of apoptosis proteins as therapeutic targets in hematological malignancies

  2012cites this paper
• Discovery of a potent small-molecule antagonist of inhibitor of apoptosis (IAP) proteins and clinical candidate for the treatment of cancer (GDC-0152).

  2012cites this paper
• MAD1 and its life as a MYC antagonist: an update.

  2012cites this paper
• The Development of Small-Molecule IAP Antagonists for the Treatment of Cancer

  2012cites this paper
• Cutting-Edge Apoptosis-Based Therapeutics

  2012cites this paper
• Withaferin A targets apoptosis inhibitor cIAP1: A potential anticancer candidate

  2012cites this paper
• Targeting IAP proteins for therapeutic intervention in cancer

  2012cites this paper
• Biochemical investigation of anti-cancer activity of Tulbaghia violacea

  2012cites this paper
• The Inhibitor of Apoptosis (IAPs) in Adaptive Response to Cellular Stress

  2012cites this paper
• BIRC2 amplification in squamous cell carcinomas of the uterine cervix

  2012cites this paper
• Genomic DNA Copy Number Alterations in Mouse Cancer Models and Human Cancer

  2012cites this paper
• A Systems Biology Approach to Characterize the Regulatory Networks Leading to Trabectedin Resistance in an In Vitro Model of Myxoid Liposarcoma

  2012cites this paper
• BIRC2 (baculoviral IAP repeat-containing 2)

  2011cites this paper
• Inhibitor of apoptosis proteins: fascinating biology leads to attractive tumor therapeutic targets.

  2011cites this paper
• YAP is a candidate oncogene for esophageal squamous cell carcinoma.

  2011cites this paper
• Cellular Inhibitor of Apoptosis Protein-1 (cIAP1) Can Regulate E2F1 Transcription Factor-mediated Control of Cyclin Transcription*

  2011cites this paper
• TRAF2 and cellular IAPs: a critical link in TNFR family signaling.

  2011cites this paper
• Garlic Constituent Diallyl Trisulfide Suppresses X-linked Inhibitor of Apoptosis Protein in Prostate Cancer Cells in Culture and In Vivo

  2011cites this paper
• Apoptotic cell signaling in cancer progression and therapy.

  2011cites this paper
• Inactivation of Merlin in malignant mesothelioma cells and the Hippo signaling cascade dysregulation

  2011cites this paper
• Yes-Associated Protein 1 Exhibits Oncogenic Property in Gastric Cancer and Its Nuclear Accumulation Associates with Poor Prognosis

  2011cites this paper
• Small-molecule pan-IAP antagonists: a patent review

  2010cites this paper
• Prediction of CCND1 amplification using plasma DNA as a prognostic marker in oesophageal squamous cell carcinoma

  2010cites this paper
• Modulation of RIP1 ubiquitylation and distribution by MeBS to sensitize cancer cells to tumor necrosis factor α‐induced apoptosis

  2010cites this paper