Safety and efficacy of an attenuated Chinese QX-like infectious bronchitis virus strain as a candidate vaccine

Ye Zhao,Jin-long Cheng,Xiao-yu Liu,Yanxin Hu,Guo-zhong Zhang

Published 2015 in Veterinary Microbiology

ABSTRACT

Highlights • An attenuated QX-like IBV strain was developed through multiple passages.• We tested the safety and efficacy of the attenuated YN strain.• The attenuated strain has a clear decrease in pathogenicity for chickens.• The vaccine based on strain IB YN was efficacious against challenge.

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