Level of expression of E-cadherin mRNA in colorectal cancer correlates with clinical outcome.

A series of colorectal carcinomas (n = 49) resected from patients with known clinical outcomes were analysed for E-cadherin expression using in situ hybridisation to measure mRNA. Patients surviving 5 years or longer (n = 31) exhibited significantly higher levels of E-cadherin mRNA than those surviving less than 5 years (n = 18, P = 0.003). These preliminary results from this small sample suggest that E-cadherin expression may be a useful prognostic marker in colorectal cancer patients.

• Publication year

  1995

• Venue

  British Journal of Cancer

• Publication date

  1995-03-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1038/bjc.1995.119PMID 7880746PMCID 2033614
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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