Cholinergic neuronal loss in the basal forebrain and mesopontine tegmentum of progressive supranuclear palsy and corticobasal degeneration

No abstract is available for this paper.

• Publication year

  2003

• Venue

  Acta Neuropathologica

• Publication date

  2003-02-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1007/s00401-002-0621-xPMID 12536222
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Corticobasal degeneration: etiopathological significance of the cytoskeletal alterations

  2004influential reference
• Discharge properties of medullary reticulospinal neurons during postural changes induced by intrapontine injections of carbachol, atropine and serotonin, and their functional linkages to hindlimb motoneurons in cats

  2004cited by this paper
• [Corticobasal degeneration].

  2001cited by this paper
• Quantification of cholinergic and select non-cholinergic mesopontine neuronal populations in the human brain.

  1999cited by this paper
• Comparative Biochemistry of Tau in Progressive Supranuclear Palsy, Corticobasal Degeneration, FTDP‐17 and Pick's Disease

  1999cited by this paper
• Neurons with choline acetyltransferase immunoreactivity and mRNA are present in the human cerebral cortex

  1999cited by this paper
• In situ mRNA hybridization study of the distribution of choline acetyltransferase in the human brain.

  1998cited by this paper
• Nigral innervation of cholinergic and glutamatergic cells in the rat mesopontine tegmentum: Light and electron microscopic anterograde tracing and immunohistochemical studies

  1998cited by this paper
• Pure akinesia manifested neuroleptic malignant syndrome: a clinical variant of progressive supranuclear palsy

  1997cited by this paper
• Excitotoxic lesions of the pedunculopontine tegmental nucleus produce contralateral hemiparkinsonism in the monkey.

  1997cited by this paper
• Excitation of the brain stem pedunculopontine tegmentum cholinergic cells induces wakefulness and REM sleep.

  1997cited by this paper
• Striatal dopaminergic loss without parkinsonism in a case of corticobasal degeneration

  1997cited by this paper
• Accuracy of the Clinical Diagnosis of Corticobasal Degeneration

  1997cited by this paper
• Progressive supranuclear palsy: a clinicopathological study of 21 cases

  1996influential reference
• Validity and Reliability of the Preliminary NINDS Neuropathologic Criteria for Progressive Supranuclear Palsy and Related Disorders

  1996cited by this paper
• [An autopsy case of corticobasal degeneration clinically misdiagnosed as Pick's disease].

  1995cited by this paper
• The neuropsychological pattern of corticobasal degeneration

  1995cited by this paper
• Immunohistochemical study on choline acetyltransferase in the spinal cord of patients with amyotrophic lateral sclerosis

  1995cited by this paper
• Pharmacological evaluation of the cholinergic system in progressive supranuclear palsy

  1994influential reference
• The syndrome of 'pure akinesia' and its relationship to progressive supranuclear palsy

  1994cited by this paper
• Heterogeneity and selectivity of the degeneration of cholinergic neurons in the basal forebrain of patients with Alzheimer's disease

  1993cited by this paper
• Modified tau is present in younger nondemented persons: a study of subcortical nuclei in Alzheimer's disease and progressive supranuclear palsy

  1991cited by this paper
• Differential vulnerability of cholinergic projections to the mediodorsal nucleus of the thalamus in senile dementia of Alzheimer type and progressive supranuclear palsy.

  1991influential reference
• Afferent and efferent connections of the laterodorsal tegmental nucleus in the rat.

  1990cited by this paper
• Immunohistochemical study of choline acetyltransferase‐immunoreactive processes and cells innervating the pontomedullary reticular formation in the rat

  1990cited by this paper
• Neuronal activities in brain-stem cholinergic nuclei related to tonic activation processes in thalamocortical systems

  1990cited by this paper
• Human reticular formation: Cholinergic neurons of the pedunculopontine and laterodorsal tegmental nuclei and some cytochemical comparisons to forebrain cholinergic neurons

  1989influential reference
• Corticobasal degeneration.

  1989cited by this paper
• Nucleus basalis (Ch4) and cortical cholinergic innervation in the human brain: Observations based on the distribution of acetylcholinesterase and choline acetyltransferase

  1988cited by this paper
• Cholinergic neurons from the dorsolateral pons project to the medial pons: a WGA-HRP and choline acetyltransferase immunohistochemical study.

  1988cited by this paper
• Cholinergic vs. noncholinergic efferents from the mesopontine tegmentum to the extrapyramidal motor system nuclei

  1988cited by this paper
• The pedunculopontine nucleus in Parkinson's disease, progressive supranuclear palsy and Alzheimer's disease.

  1988influential reference
• Neuronal loss in the pedunculopontine tegmental nucleus in Parkinson disease and in progressive supranuclear palsy.

  1987influential reference
• Loss of pedunculopontine neurons in progressive supranuclear palsy

  1987influential reference
• Cholinergic correlates of cognitive impairment in Parkinson's disease: comparisons with Alzheimer's disease.

  1985influential reference
• The nucleus basalis of Meynert in neurological disease: A quantitative morphological study

  1985cited by this paper
• Dopaminergic and cholinergic lesions in progressive supranuclear palsy

  1985cited by this paper
• A cytoarchitectonic and histochemical study of nucleus basalis and associated cell groups in the normal human brain.

  1984influential reference
• The basal nucleus of Meynert in patients with progressive supranuclear palsy.

  1984influential reference
• Sleep disturbances in progressive supranuclear palsy.

  1978cited by this paper
• PROGRESSIVE SUPRANUCLEAR PALSY

  1969influential reference
• Corticodentatonigral degeneration with neuronal achromasia.

  1968cited by this paper
• Corticodentatonigral degeneration with neuronal achromasia: a progressive disorder of late adult life.

  1967cited by this paper
• Progressive Supranuclear Palsy: A Heterogeneous Degeneration Involving the Brain Stem, Basal Ganglia and Cerebellum With Vertical Gaze and Pseudobulbar Palsy, Nuchal Dystonia and Dementia

  1964cited by this paper

• Cholinergic substrates of gait and postural impairments in Progressive Supranuclear Palsy

  2026cites this paper
• The cholinergic basal forebrain and its role in neurodegeneration

  2025cites this paper
• Brain atrophy and cholinergic denervation in progressive supranuclear palsy: an MRI and [18F]-FEOBV PET study

  2025cites this paper
• Selective cellular and regional vulnerability in frontotemporal lobar degeneration: a scoping review

  2025cites this paper
• PET evaluation of cholinergic system differences in progressive supranuclear palsy and age-matched controls using [18F]VAT.

  2025cites this paper
• Low Dose Amantadine and Escitalopram in Progressive Supranuclear Palsy and Multiple System Atrophy

  2024cites this paper
• Nucleus Basalis of Meynert degeneration predicts cognitive decline in Corticobasal Syndrome.

  2024influential citation
• A Window Into Basal Forebrain Cholinergic Dysfunction in Patients With Cortical Basal Syndrome.

  2024cites this paper
• Pathomechanisms of cognitive impairment in progressive supranuclear palsy

  2023cites this paper
• Differential cholinergic systems’ changes in progressive supranuclear palsy versus Parkinson’s disease: an exploratory analysis

  2022cites this paper
• Reduction in Volume of Nucleus Basalis of Meynert Is Specific to Parkinson’s Disease and Progressive Supranuclear Palsy but Not to Multiple System Atrophy

  2022cites this paper
• Resistance of Basal Forebrain Cholinergic Neurons to TDP-43 Proteinopathy in Primary Progressive Aphasia.

  2022cites this paper
• Basal forebrain cholinergic system in the dementias: Vulnerability, resilience, and resistance

  2021cites this paper
• Molecular Imaging of Extrapyramidal Movement Disorders With Dementia: The 4R Tauopathies.

  2021cites this paper
• Suicidal and death ideation in patients with progressive supranuclear palsy and corticobasal syndrome.

  2020cites this paper
• Alteration of the Dopamine Receptors’ Expression in the Cerebellum of the Lysosomal Acid Phosphatase 2 Mutant (Naked–Ataxia (NAX)) Mouse

  2020cites this paper
• Basal forebrain atrophy in frontotemporal dementia

  2020influential citation
• The Dual Nature of Onuf’s Nucleus: Neuroanatomical Features and Peculiarities, in Health and Disease

  2020cites this paper
• Overview of sleep disturbances and their management in Parkinson plus disorders.

  2020cites this paper
• Falls in Progressive Supranuclear Palsy

  2019cites this paper
• Progressive supranuclear palsy, multiple system atrophy and corticobasal degeneration.

  2019cites this paper
• Dichotomy between motor and cognitive functions of midbrain cholinergic neurons.

  2019cites this paper
• Selektive neuronale Vulnerabilität neurodegenerativer Erkrankungen am Beispiel des Thalamus

  2018cites this paper
• Pedunculopontine tegmentum cholinergic loss leads to a progressive decline in motor abilities and neuropathological changes resembling progressive supranuclear palsy

  2018cites this paper
• Neuroimaging of Sleep Disturbances in Movement Disorders

  2018cites this paper
• Normal and pathological neuronal distribution of the human mesencephalic locomotor region

  2018influential citation
• Neurotransmitter deficits from frontotemporal lobar degeneration

  2018cites this paper
• Selective Vulnerability of Brainstem Nuclei in Distinct Tauopathies: A Postmortem Study

  2018cites this paper
• The fate of the brain cholinergic neurons in neurodegenerative diseases.

  2017influential citation
• The anterior and posterior pedunculopontine tegmental nucleus are involved in behavior and neuronal activity of the cuneiform and entopeduncular nuclei.

  2016cites this paper
• Cholinergic depletion and basal forebrain volume in primary progressive aphasia

  2016influential citation
• A Review of Treatment Options for Progressive Supranuclear Palsy

  2016cites this paper
• Progressive supranuclear palsy: what do we know about it?

  2015cites this paper
• Deficits in motor performance after pedunculopontine lesions in rats – impairment depends on demands of task

  2014cites this paper
• Nocturnal Manifestations of Atypical Parkinsonian Disorders

  2014cites this paper
• The influences of age on olfaction: a review

  2014cites this paper
• Continuous stimulation of the pedunculopontine tegmental nucleus at 40 Hz affects preparative and executive control in a delayed sensorimotor task and reduces rotational movements induced by apomorphine in the 6-OHDA parkinsonian rat.

  2014cites this paper
• Don’t forget non-Alzheimer dementias

  2014cites this paper
• Brainstem Cholinergic Systems

  2012cites this paper
• Progressive supranuclear palsy and corticobasal degeneration.

  2011cites this paper
• Milestones in atypical and secondary Parkinsonisms

  2011cites this paper
• Rivastigmine for the treatment of dementia in patients with progressive supranuclear palsy: Clinical observations as a basis for power calculations and safety analysis

  2010cites this paper
• Progressieve Supranucleaire Verlamming. Interventie middels acetylcholineesteraseremmer?

  2009cites this paper
• Physiological identification of the human pedunculopontine nucleus

  2009cites this paper
• Welcome to the club: substantial sleep dysfunction also in progressive supranuclear palsy.

  2009cites this paper
• [Progressive supranucleair palsy: acetylcholineeserase-inhibitor a possible therapy?].

  2009cites this paper
• Mesopontine cholinergic neuron involvement in Lewy body dementia and multiple system atrophy

  2008cites this paper
• Serum interleukin (IL-2, IL-10, IL-6, IL-4), TNFalpha, and INFgamma concentrations are elevated in patients with atypical and idiopathic parkinsonism.

  2008cites this paper
• Cholinergic modulation of midbrain dopaminergic systems.

  2008cites this paper
• Neurobiology of sleep disturbances in neurodegenerative disorders.

  2008cites this paper
• The pedunculopontine nucleus in developmental disorders of the basal ganglia

  2008cites this paper
• Loss of cholinergic neurons in the pedunculopontine nucleus in Parkinson's disease is related to disability of the patients.

  2008cites this paper
• The neuronal activity of thalamic parafascicular nucleus is conversely regulated by nigrostriatal pathway and pedunculopontine nucleus in the rat.

  2008cites this paper
• Muscarinic Receptors in the Thalamus in Progressive Supranuclear Palsy and Other Neurodegenerative Disorders

  2007influential citation
• Sleep and vigilance in corticobasal degeneration: a descriptive study.

  2007cites this paper
• Corticobasal degeneration.

  2007cites this paper
• Treatment of Dementia in Parkinsonian Syndromes with Cholinesterase Inhibitors

  2007cites this paper
• Lesion of the pedunculopontine nucleus reverses hyperactivity of the subthalamic nucleus and substantia nigra pars reticulata in a 6‐hydroxydopamine rat model

  2006cites this paper
• Abnormal head nociceptive withdrawal reaction to facial nociceptive stimuli in Parkinson's disease.

  2005cites this paper
• Unilateral lesion of the pedunculopontine nucleus induces hyperactivity in the subthalamic nucleus and substantia nigra in the rat

  2005cites this paper
• Current and Future Therapeutic Approaches

  2005cites this paper
• 進行性核上性麻痺の治療up-to-date2005

  2005cites this paper
• Cholinergic systems in progressive supranuclear palsy.

  2004cites this paper
• Update on progressive supranuclear palsy

  2004cites this paper
• NeuroImage: Clinical

  year unknowncites this paper
• Milestones in Atypical and Secondary Parkinsonisms Advances in the past 25 Years

  year unknowncites this paper