An analysis of the typing results of a 70-member chronic lymphatic leukemia B cell panel revealed evidence for 13 possible groups of the Merrit alloantigenic system. Six of these appeared possibly allelic and may represent a segregant series. The CLL panel was also fully typed for HLA and some degree of linkage dysequilibrium between Merrit and HLA seemed apparent from the data. Merrit antibodies can be absorbed out with selected surface membrane immunoglobulin (SMIG)-positive normal lymphocytes and less so or not at all with E rosette-forming T cells or Fc-positive SMIG-negative lymphocytes.
The merrit alloantigenic system of human B lymphocytes: evidence for thirteen possible factors including one six-member segregant series.
R. Walford,T. Gossett,G. Troup,R. Gatti,K. Mittal,A. Robins,G. Ferrara,E. Zeller
Published 1976 in Journal of Immunology
ABSTRACT
PUBLICATION RECORD
- Publication year
1976
- Venue
Journal of Immunology
- Publication date
1976-06-01
- Fields of study
Biology, Medicine
- Identifiers
- External record
- Source metadata
Semantic Scholar, PubMed
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