DNA methylation: evolution of a bacterial immune function into a regulator of gene expression and genome structure in higher eukaryotes.

No abstract is available for this paper.

• Publication year

  1990

• Venue

  Philosophical transactions of the Royal Society of London. Series B, Biological sciences

• Publication date

  1990-01-30

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1098/RSTB.1990.0002PMID 1968655
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Cytosine-specific type II DNA methyltransferases. A conserved enzyme core with variable target-recognizing domains.

  1989cited by this paper
• Predictive motifs derived from cytosine methyltransferases.

  1989cited by this paper
• Structure of the Drosophila DNA topoisomerase II gene. Nucleotide sequence and homology among topoisomerases II.

  1989cited by this paper
• Reversible methylation and inactivation of marker genes in sequentially transformed tobacco plants

  1989cited by this paper
• The zinc finger region of simian virus 40 large T antigen

  1989cited by this paper
• Zinc fingers: gilt by association.

  1988cited by this paper
• DNA methylation and gene activity.

  1988cited by this paper
• Fingering too many proteins.

  1988cited by this paper
• Cloning and sequencing of a cDNA encoding DNA methyltransferase of mouse cells. The carboxyl-terminal domain of the mammalian enzymes is related to bacterial restriction methyltransferases.

  1988cited by this paper
• Type II restriction--modification systems.

  1988cited by this paper
• Zinc fingers: gilt by association.

  1988cited by this paper
• Tat protein from human immunodeficiency virus forms a metal-linked dimer.

  1988cited by this paper
• McrA and McrB restriction phenotypes of some E. coli strains and implications for gene cloning.

  1988cited by this paper
• Genomic imprinting. Memories of mother and father.

  1987cited by this paper
• Rearrangement of duplicated DNA in specialized cells of Neurospora.

  1987cited by this paper
• Memories of mother and father

  1987cited by this paper
• DNA methylation in wheat. Purification and properties of DNA methyltransferase.

  1987cited by this paper
• CpG-rich islands and the function of DNA methylation

  1986cited by this paper
• Of urfs and orfs : a primer on how to analyze devised amino acid sequences

  1986cited by this paper
• Meiotic recombination between duplicated genetic elements in Saccharomyces cerevisiae.

  1985cited by this paper
• Growth-dependent expression of multiple species of DNA methyltransferase in murine erythroleukemia cells.

  1985cited by this paper
• Two DNA methyltransferases from murine erythroleukemia cells: purification, sequence specificity, and mode of interaction with DNA.

  1983cited by this paper
• Biochemical characterization of topoisomerase I purified from avian erythrocytes.

  1983cited by this paper
• Hen's Teeth and Horse's Toes

  1983cited by this paper
• DNA methylation and gene activity.

  1983cited by this paper
• Substrate and sequence specificity of a eukaryotic DNA methylase

  1982cited by this paper
• Two-dimensional DNA electrophoresis applied to the study of DNA methylation and the analysis of genome size in Myxococcus xanthus.

  1982cited by this paper
• Structure of a triclinic ternary complex of horse liver alcohol dehydrogenase at 2.9 A resolution.

  1981cited by this paper
• Selfish genes, the phenotype paradigm and genome evolution

  1980cited by this paper
• Variable patterns of total DNA and rDNA methylation in animals.

  1980cited by this paper
• Selfish DNA: the ultimate parasite

  1980cited by this paper
• Methylated bases in mycoplasmal DNA.

  1980cited by this paper
• Evolution by Gene Duplication

  1970cited by this paper

• Genome-wide and gene-specific DNA methylation across developmental stages in Pogonomyrmex californicus: A socially polymorphic ant.

  2025cites this paper
• Methylome differences among barley inbreds and their association with genomic, transcriptomic, and phenotypic variation

  2025cites this paper
• Roles of endogenous retroviral elements in the establishment and maintenance of imprinted gene expression

  2024cites this paper
• Mutation Rate Variation and Other Challenges in 2-LTR Dating of Primate Endogenous Retrovirus Integrations

  2024cites this paper
• Selection on synonymous sites: the unwanted transcript hypothesis

  2024cites this paper
• Then and Now in Eukaryotic DNA Methylation.

  2024cites this paper
• The role of ribosomal DNA methylation in embryonic development, aging and diseases

  2024cites this paper
• Mixed Patterns of Intergenerational DNA Methylation Inheritance in Acropora

  2024cites this paper
• MITE infestation accommodated by genome editing in the germline genome of the ciliate Blepharisma

  2023cites this paper
• Comparative epigenome analysis using Infinium DNA methylation BeadChips

  2023cites this paper
• The model diatom Phaeodactylum tricornutum provides insights into the diversity and function of microeukaryotic DNA methyltransferases

  2023cites this paper
• Comprehensive profiling of epigenetic modifications in fast-growing moso bamboo shoots.

  2022cites this paper
• The Role of DNA Methylation in Genome Defense in Cnidaria and Other Invertebrates

  2022cites this paper
• A Broad Survey of Gene Body and Repeat Methylation in Cnidaria Reveals a Complex Evolutionary History

  2022cites this paper
• Role of Transposable Elements in Genome Stability: Implications for Health and Disease

  2022cites this paper
• MITE infestation of germline accommodated by genome editing in Blepharisma

  2022cites this paper
• Genome scale metabolic model combined with single molecule real-time sequencing to analyze Actinomycete chromosomal heterogeneity.

  2022cites this paper
• The transposable element-rich genome of the cereal pest Sitophilus oryzae

  2021cites this paper
• Effect of Cryopreservation on the Genome of Sperm in Animals and Humans

  2021cites this paper
• Rewiring of chromatin state and gene expression by transposable elements

  2021cites this paper
• More than causing (epi)genomic instability: emerging physiological implications of transposable element modulation

  2021cites this paper
• 5-Methylcytosine and 5-hydroxymethylcytosine in psychiatric epigenetics

  2021cites this paper
• The Phylogenetic Relationships of a 4mC/6mA DNA Methyltransferase in Prokaryotes.

  2020cites this paper
• DNA methylation enables transposable element-driven genome expansion

  2020influential citation
• Identification of DNA (de)methylation-related genes and their transcriptional response to environmental challenges in an invasive model ascidian.

  2020cites this paper
• Induced Methylation in Plants as a Crop Improvement Tool: Progress and Perspectives

  2020cites this paper
• DNMTs and Impact of CpG Content, Transcription Factors, Consensus Motifs, lncRNAs, and Histone Marks on DNA Methylation

  2020cites this paper
• The methylomes of Lake Malawi cichlids reveal epigenetic variation associated with phenotypic diversification

  2020cites this paper
• Mapping epigenetic divergence in the massive radiation of Lake Malawi cichlid fishes

  2020cites this paper
• Comparative genomic analysis of Erwinia amylovora reveals novel insights in phylogenetic arrangement, plasmid diversity, and streptomycin resistance.

  2020cites this paper
• Micronutrient supplementation affects transcriptional and epigenetic regulation of lipid metabolism in a dose-dependent manner

  2020cites this paper
• Is imprinting the result of “friendly fire” by the host defense system?

  2020cites this paper
• Differences in DNA Methylation Between Disease-Resistant and Disease-Susceptible Chinese Tongue Sole (Cynoglossus semilaevis) Families

  2019cites this paper
• LEVEL AND SOURCE OF FAT IN THE DIET OF BEEF COWS

  2019influential citation
• Lamarckian realities: the CRISPR-Cas system and beyond

  2019cites this paper
• Lamarckian realities: the CRISPR-Cas system and beyond

  2019cites this paper
• Promoter Methylation Regulates ApoA-I Gene Transcription in Chicken Abdominal Adipose Tissue.

  2019cites this paper
• Snart, Charles J.P. (2011) Transcriptome analysis of honey bee larvae following neonicotinoid exposure. MRes

  2018influential citation
• Epigenetic agents in combined anticancer therapy.

  2018cites this paper
• The epigenetic alterations of endogenous retroelements in aging.

  2018cites this paper
• Abnormal Epigenetic Regulation of Immune System during Aging

  2018influential citation
• DNA Methylation in Eukaryotes: Regulation and Function

  2017cites this paper
• Inter-individual variation in DNA methylation is largely restricted to tissue-specific differentially methylated regions in maize

  2017cites this paper
• Stress and the Emerging Roles of Chromatin Remodeling in Signal Integration and Stable Transmission of Reversible Phenotypes

  2017cites this paper
• Transcription factors as readers and effectors of DNA methylation

  2016cites this paper
• Forensic DNA methylation profiling from evidence material for investigative leads

  2016cites this paper
• Epigenetic regulation of specific transcription factors in osteogenicdifferentiation of mesenchymal stem cells

  2016cites this paper
• Adenine methylation in eukaryotes: Apprehending the complex evolutionary history and functional potential of an epigenetic modification

  2015cites this paper
• Computational Methods in Epigenetics

  2015cites this paper
• Adaptive epibiochemistry and epigenetics

  2015cites this paper
• Genomic imprinting in mammals—memories of generations past

  2015cites this paper
• PERSONALIZED EPIGENETICS

  2015cites this paper
• Turnover and function of DNA methylation at transcription factor binding sites

  2014influential citation
• HDAC4 integrates PTH and sympathetic signaling in osteoblasts

  2014cites this paper
• Epigenetic mechanisms in autism spectrum disorder.

  2014cites this paper
• 5-Methycytosine and 5-Hydroxymethylcytosine in Psychiatric Epigenetics

  2014cites this paper
• Cancer epigenetics: tumor heterogeneity, plasticity of stem-like states, and drug resistance.

  2014cites this paper
• Demethylation of the Epstein-Barr virus origin of lytic replication and of the immediate early gene BZLF1 is DNA replication independent

  2014cites this paper
• Epigenetic Regulation of Osteogenic and Chondrogenic Differentiation of Mesenchymal Stem Cells in Culture

  2013cites this paper
• Epigenetic Regulation of Gene Expression: Emerging Applications for Horses

  2013cites this paper
• Mutations in EDM2 selectively affect silencing states of transposons and induce plant developmental plasticity

  2013cites this paper
• DNA methylation as a mechanism of nutritional plasticity: limited support from horned beetles.

  2013cites this paper
• Presidential address. Transposable elements, epigenetics, and genome evolution.

  2012cites this paper
• Homologous Recombination and Gene Silencing in Plants

  2012cites this paper
• Gene flow and biological conflict systems in the origin and evolution of eukaryotes

  2012cites this paper
• Transposable Elements, Epigenetics, and Genome Evolution

  2012cites this paper
• Defining the protein complement of CpG islands

  2011cites this paper
• Epigenetics: Linking Genotype and Phenotype in Development and Evolution

  2011cites this paper
• Evidence for Widespread Genomic Methylation in the Migratory Locust, Locusta migratoria (Orthoptera: Acrididae)

  2011cites this paper
• Natural history of eukaryotic DNA methylation systems.

  2011cites this paper
• DNA methylation in insects: on the brink of the epigenomic era

  2011cites this paper
• Evolution of eukaryotic DNA methylation and the pursuit of safer sex.

  2010cites this paper
• Hprt mutant frequency and p53 gene status in mice chronically exposed by inhalation to benzene.

  2010cites this paper
• DNA methylation prevents CTCF-mediated silencing of the oncogene BCL6 in B cell lymphomas

  2010influential citation
• Epigenetics and Evolution: An Overview

  2010cites this paper
• CHAPTER 5 – Epigenomics and Its Implications for Medicine

  2009cites this paper
• In Silico Prediction of Two Classes of Honeybee Genes with CpG Deficiency or CpG Enrichment and Sorting According to Gene Ontology Classes

  2009cites this paper
• The Methyl-CpG Binding Proteins Mecp2, Mbd2 and Kaiso Are Dispensable for Mouse Embryogenesis, but Play a Redundant Function in Neural Differentiation

  2009cites this paper
• The Importance Of Epigenetic Alterations In Epstein-Barr Virus-Related Lymphomas

  2009cites this paper
• Effect of DNA Methylation on 18S rRNA Gene Sequences during Culture of Taxus chinensis Cells

  2009cites this paper
• Explorer The Transcriptional Response of Drosophila melanogaster to Infection with the Sigma Virus (Rhabdoviridae)

  2009cites this paper
• Suicidal function of DNA methylation in age-related genome disintegration.

  2009cites this paper
• Transgenerational Epigenetic Inheritance: Prevalence, Mechanisms, and Implications for the Study of Heredity and Evolution

  2009cites this paper
• Microbe-induced epigenetic alterations in host cells: the coming era of patho-epigenetics of microbial infections. A review.

  2009cites this paper
• Epigenetic regulation of the honey bee transcriptome: unravelling the nature of methylated genes

  2009cites this paper
• A Cytosine Methyltransferase Homologue Is Essential for Sexual Development in Aspergillus nidulans

  2008cites this paper
• LTR retrotransposons and the evolution of dosage compensation in Drosophila

  2008cites this paper
• Molecular typing, serotyping and cytotoxicity testing of Campylobacter jejuni strains isolated from commercial broilers in Puerto Rico

  2008cites this paper
• MBD4-Mediated Glycosylase Activity on a Chromatin Template Is Enhanced by Acetylation

  2008cites this paper
• Cooperative activity of DNA methyltransferases for maintenance of symmetrical and non-symmetrical cytosine methylation in Arabidopsis thaliana

  2008cites this paper
• Genome-wide analysis of Arabidopsis thaliana DNA methylation uncovers an interdependence between methylation and transcription

  2007cites this paper
• DNA Methylation Errors and Cancer1

  2006cites this paper
• Effect of hypermethylation of CCWGG sequences in DNA of Mesembryanthemum crystallinum plants on their adaptation to salt stress

  2006cites this paper
• MBD family proteins: reading the epigenetic code

  2006cites this paper
• The evolution of information in the major transitions.

  2006cites this paper
• The evolution of immune mechanisms.

  2006cites this paper
• Characterisation of transposable elements of cassava (Manihot esculenta Crantz)

  2005cites this paper
• Host defenses to transposable elements and the evolution of genomic imprinting

  2005influential citation
• Short retroposons in eukaryotic genomes.

  2005influential citation
• DNA methylation, nucleosome formation and positioning.

  2005cites this paper