Dual specificity phosphotase 18, interacting with SAPK, dephosphorylates SAPK and inhibits SAPK/JNK signal pathway in vivo.

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Frontiers in Bioscience

• Publication date

  2006-09-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.2741/2001PMID 16720344
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The novel protein-tyrosine phosphatase PTP20 is a positive regulator of PC12 cell neuronal differentiation.

  2010cited by this paper
• The JNK signal transduction pathway.

  2007cited by this paper
• From JNK to Pay Dirt: Jun Kinases, their Biochemistry, Physiology and Clinical Importance

  2005cited by this paper
• c-Jun-NH2 Kinase (JNK) Contributes to the Regulation of c-Myc Protein Stability*

  2004influential reference
• Protein Kinases and Phosphatases: The Yin and Yang of Protein Phosphorylation and Signaling Review

  2004cited by this paper
• Molecular cloning and characterization of a novel dual-specificity phosphatase18 gene from human fetal brain.

  2003cited by this paper
• Large-scale analysis of the human and mouse transcriptomes

  2002cited by this paper
• ATM Mediates Phosphorylation at Multiple p53 Sites, Including Ser46, in Response to Ionizing Radiation*

  2002cited by this paper
• Combinatorial control of the specificity of protein tyrosine phosphatases.

  2001influential reference
• Mammalian MAP kinase signalling cascades

  2001cited by this paper
• MKP-7, a Novel Mitogen-activated Protein Kinase Phosphatase, Functions as a Shuttle Protein*

  2001cited by this paper
• c-Jun NH2-terminal Kinase Targeting and Phosphorylation of Heat Shock Factor-1 Suppress Its Transcriptional Activity*

  2000influential reference
• Contribution of receptor/G protein signaling to cell growth and transformation

  2000cited by this paper
• Distinct signalling pathways mediate the cAMP response element (CRE)-dependent activation of the calcitonin gene-related peptide gene promoter by cAMP and nerve growth factor.

  2000influential reference
• MAP kinase pathways: molecular plug-and-play chips for the cell

  2000cited by this paper
• Molecular Cloning and Characterization of a Novel Dual Specificity Phosphatase, MKP-5*

  1999influential reference
• Extracellular Regulated Kinases (ERK) 1 and ERK2 Are Authentic Substrates for the Dual-specificity Protein-tyrosine Phosphatase VHR

  1999cited by this paper
• Molecular cloning and characterization of a novel dual-specificity protein phosphatase possibly involved in spermatogenesis.

  1999cited by this paper
• Mitogen-activated Protein Kinase Phosphatases Inactivate Stress-activated Protein Kinase Pathways in Vivo*

  1997cited by this paper
• Molecular Cloning and Functional Characterization of a Novel Mitogen-activated Protein Kinase Phosphatase, MKP-4*

  1997cited by this paper
• The Novel Protein-tyrosine Phosphatase PTP20 Is a Positive Regulator of PC12 Cell Neuronal Differentiation*

  1996cited by this paper
• The Mitogen-activated Protein Kinase Phosphatases PAC1, MKP-1, and MKP-2 Have Unique Substrate Specificities and Reduced Activity in Vivo toward the ERK2 sevenmaker Mutation (*)

  1996cited by this paper
• MKP-3, a Novel Cytosolic Protein-tyrosine Phosphatase That Exemplifies a New Class of Mitogen-activated Protein Kinase Phosphatase (*)

  1996cited by this paper
• The Dual Specificity Phosphatases M3/6 and MKP-3 Are Highly Selective for Inactivation of Distinct Mitogen-activated Protein Kinases*

  1996cited by this paper
• hVH‐5: A Protein Tyrosine Phosphatase Abundant in Brain that Inactivates Mitogen‐Activated Protein Kinase

  1995cited by this paper
• Integration of MAP kinase signal transduction pathways at the serum response element.

  1995cited by this paper
• Protein kinases and phosphatases: the yin and yang of protein phosphorylation and signaling.

  1995cited by this paper
• JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain.

  1994cited by this paper
• Requirement for integration of signals from two distinct phosphorylation pathways for activation of MAP kinase

  1990cited by this paper

• Dual-specificity phosphatases: Potential targets for cognitive impairment induced by chronic kidney disease.

  2025cites this paper
• Hypoxia-induced HIF1A activates DUSP18-mediated MAPK14 dephosphorylation to promote hepatocellular carcinoma cell migration and invasion.

  2022cites this paper
• The emerging roles of dual-specificity phosphatases and their specific characteristics in human cancer.

  2021cites this paper
• Epigenetic inheritance of circadian period in clonal cells

  2020cites this paper
• VGF-derived peptide TLQP-21 modulates microglial function through C3aR1 signaling pathways and reduces neuropathology in 5xFAD mice

  2020cites this paper
• Phosphorylation Dynamics of JNK Signaling: Effects of Dual-Specificity Phosphatases (DUSPs) on the JNK Pathway

  2019cites this paper
• Dual-specificity phosphatase 18 modulates the SUMOylation and aggregation of Ataxin-1.

  2018cites this paper
• 9 Prostate Cancer Dephosphorylation Atlas

  2017cites this paper
• Comparative analysis of molecular mechanism of spinal cord injury with time based on bioinformatics data

  2015cites this paper
• Elevated expression of activins promotes muscle wasting and cachexia

  2014cites this paper
• Emerging Roles of Atypical Dual Specificity Phosphatases in Cancer

  2013cites this paper
• Altered Gene Expression Patterns in Muscle Ring Finger 1 Null Mice During Denervation 2 and Dexamethasone Induced Muscle Atrophy 3 4

  2013cites this paper
• Molecular mechanisms of glucocorticoid action in mast cells.

  2013cites this paper
• Altered gene expression patterns in muscle ring finger 1 null mice during denervation- and dexamethasone-induced muscle atrophy.

  2013cites this paper
• Funktion der Dual-Specificity-Phosphatase-5 in Zellen des angeborenen und adaptiven Immunsystems

  2012cites this paper
• Prostate Cancer Dephosphorylation Atlas

  2011cites this paper
• A novel phosphatase modulating the DNA damage response and the tumor suppressor p53

  2011influential citation
• REGULATION OF PROINFLAMMATORY CYTOKINES BY MAP KINASE PHOSPHAPATASE IN AVIAN INFLUENZA VIRUS INFECTED CHICKEN MACROPHAGES

  2011cites this paper
• Dual-specificity phosphatases: critical regulators with diverse cellular targets.

  2009cites this paper
• Protein tyrosine phosphatases in autoimmunity.

  2008cites this paper
• Dual Specificity Phosphatases 18 and 21 Target to Opposing Sides of the Mitochondrial Inner Membrane

  2008cites this paper
• Spatiotemporal Regulation of ERK2 by Dual Specificity Phosphatases*S⃞

  2008cites this paper
• Mitogen-Activated Protein (MAP) Kinase/MAP Kinase Phosphatase Regulation: Roles in Cell Growth, Death, and Cancer

  2008cites this paper
• Regulation of MAP kinases by MAP kinase phosphatases.

  2007cites this paper
• Targeting dual-specificity phosphatases: manipulating MAP kinase signalling and immune responses

  2007cites this paper