Targeting dual-specificity phosphatases: manipulating MAP kinase signalling and immune responses

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Nature reviews. Drug discovery

• Publication date

  2007-05-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1038/nrd2289PMID 17473844
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• A novel amplification target, DUSP26, promotes anaplastic thyroid cancer cell growth by inhibiting p38 MAPK activity

  2007cited by this paper
• Dusp6 (Mkp3) is a negative feedback regulator of FGF-stimulated ERK signaling during mouse development

  2007cited by this paper
• Dual specificity phosphatase 1 (DUSP1) regulates a subset of LPS-induced genes and protects mice from lethal endotoxin shock

  2006cited by this paper
• Novel benzofuran inhibitors of human mitogen-activated protein kinase phosphatase-1.

  2006cited by this paper
• Cooperation of ERK and SCFSkp2 for MKP-1 Destruction Provides a Positive Feedback Regulation of Proliferating Signaling*

  2006cited by this paper
• ERK Signaling Is a Molecular Switch Integrating Opposing Inputs from B Cell Receptor and T Cell Cytokines to Control TLR4-Driven Plasma Cell Differentiation1

  2006cited by this paper
• Selective Requirement of p38α MAPK in Cytokine-Dependent, but Not Antigen Receptor-Dependent, Th1 Responses1

  2006cited by this paper
• A functional RNAi screen for regulators of receptor tyrosine kinase and ERK signalling

  2006cited by this paper
• A randomized, multicenter, double-blind, placebo-controlled phase 2 trial of ISA247 in patients with chronic plaque psoriasis.

  2006cited by this paper
• CXCL12 and C5a trigger cell migration via a PAK1/2-p38alpha MAPK-MAPKAP-K2-HSP27 pathway.

  2006cited by this paper
• MAP kinase phosphatase 1 controls innate immune responses and suppresses endotoxic shock

  2006cited by this paper
• MKP1/CL100 controls tumor growth and sensitivity to cisplatin in non-small-cell lung cancer

  2006cited by this paper
• Dynamic regulation of pro- and anti-inflammatory cytokines by MAPK phosphatase 1 (MKP-1) in innate immune responses

  2006cited by this paper
• Antiinflammatory effects of dexamethasone are partly dependent on induction of dual specificity phosphatase 1

  2006cited by this paper
• Dual specificity phosphotase 18, interacting with SAPK, dephosphorylates SAPK and inhibits SAPK/JNK signal pathway in vivo.

  2006cited by this paper
• Mice lacking MAP kinase phosphatase-1 have enhanced MAP kinase activity and resistance to diet-induced obesity.

  2006cited by this paper
• Biochemical and biological characterization of a neuroendocrine‐associated phosphatase

  2006cited by this paper
• Protein tyrosine phosphatases: from genes, to function, to disease

  2006cited by this paper
• Targeting signal transduction as a strategy to treat inflammatory diseases

  2006cited by this paper
• The dual specificity phosphatase transcriptome of the murine thymus.

  2006cited by this paper
• The extracellular signal-regulated kinase: Multiple substrates regulate diverse cellular functions

  2006cited by this paper
• Positive regulation of immune cell function and inflammatory responses by phosphatase PAC-1

  2006cited by this paper
• Essential Role of MAPK Phosphatase-1 in the Negative Control of Innate Immune Responses

  2006cited by this paper
• Loss of the VHR dual-specific phosphatase causescell-cycle arrest and senescence

  2006cited by this paper
• Disruption of the Jnk2 (Mapk9) gene reduces destructive insulitis and diabetes in a mouse model of type I diabetes.

  2005cited by this paper
• p38γ regulates the localisation of SAP97 in the cytoskeleton by modulating its interaction with GKAP

  2005cited by this paper
• Abrogation of DUSP6 by hypermethylation in human pancreatic cancer

  2005cited by this paper
• MKP-8, a novel MAPK phosphatase that inhibits p38 kinase.

  2005cited by this paper
• Control of dual‐specificity phosphatase‐1 expression in activated macrophages by IL‐10

  2005cited by this paper
• New insights into the catalytic activation of the MAPK phosphatase PAC-1 induced by its substrate MAPK ERK2 binding.

  2005cited by this paper
• The Benzo[c]phenanthridine Alkaloid, Sanguinarine, Is a Selective, Cell-active Inhibitor of Mitogen-activated Protein Kinase Phosphatase-1*

  2005cited by this paper
• The Role of Mitogen-activated Protein Kinase Phosphatase-1 in the Response of Alveolar Macrophages to Lipopolysaccharide

  2005cited by this paper
• The Dual-Specificity Protein Phosphatase DUSP9/MKP-4 Is Essential for Placental Function but Is Not Required for Normal Embryonic Development

  2005cited by this paper
• The role of erk1 and erk2 in multiple stages of T cell development.

  2005cited by this paper
• Reactive Oxygen Species Promote TNF -Induced Death and Sustained JNK Activation by Inhibiting MAP Kinase Phosphatases

  2005cited by this paper
• Specific Inactivation and Nuclear Anchoring of Extracellular Signal-Regulated Kinase 2 by the Inducible Dual-Specificity Protein Phosphatase DUSP5

  2005cited by this paper
• Subcellular localization determines MAP kinase signal output.

  2005cited by this paper
• Dual‐specificity phosphatase 1 and serum/glucocorticoid‐regulated kinase are downregulated in prostate cancer

  2005cited by this paper
• Generation and Characterization of p38β (MAPK11) Gene-Targeted Mice

  2005cited by this paper
• A genomic perspective on protein tyrosine phosphatases: gene structure, pseudogenes, and genetic disease linkage

  2004cited by this paper
• Both Nuclear-Cytoplasmic Shuttling of the Dual Specificity Phosphatase MKP-3 and Its Ability to Anchor MAP Kinase in the Cytoplasm Are Mediated by a Conserved Nuclear Export Signal*

  2004cited by this paper
• Counting on mitogen-activated protein kinases--ERKs 3, 4, 5, 6, 7 and 8.

  2004cited by this paper
• Regulation of innate and adaptive immune responses by MAP kinase phosphatase 5

  2004cited by this paper
• Survival factor-induced extracellular signal-regulated kinase phosphorylates BIM, inhibiting its association with BAX and proapoptotic activity.

  2004cited by this paper
• The PAC-1 dual specificity phosphatase predicts poor outcome in serous ovarian carcinoma.

  2004cited by this paper
• Protein tyrosine phosphatases in the human genome.

  2004cited by this paper
• Mitogen-activated protein kinases in apoptosis regulation

  2004cited by this paper
• Focal adhesion and actin dynamics: a place where kinases and proteases meet to promote invasion.

  2004cited by this paper
• ERK and p38 MAPK-Activated Protein Kinases: a Family of Protein Kinases with Diverse Biological Functions

  2004cited by this paper
• Feedback regulation of lymphocyte signalling

  2004cited by this paper
• P53 transactivates the phosphatase MKP1 through both intronic and exonic p53 responsive elements

  2004cited by this paper
• MAP kinases and cell migration

  2004cited by this paper
• ReviewProtein Tyrosine Phosphatases in the Human

  2004cited by this paper
• Molecular recognitions in the MAP kinase cascades.

  2003cited by this paper
• Characterization of a variant of PAC-1 in large granular lymphocyte leukemia.

  2003cited by this paper
• Overexpression of mitogen-activated protein kinase phosphatases MKP1, MKP2 in human breast cancer.

  2003cited by this paper
• The Phosphatase MKP1 Is a Transcriptional Target of p53 Involved in Cell Cycle Regulation*

  2003cited by this paper
• Feedback control of the protein kinase TAK1 by SAPK2a/p38α

  2003cited by this paper
• Molecular mechanisms regulating Th1 immune responses.

  2003influential reference
• The specificities of protein kinase inhibitors: an update.

  2003cited by this paper
• Cell-active dual specificity phosphatase inhibitors identified by high-content screening.

  2003cited by this paper
• Solution structure of the MAPK phosphatase PAC-1 catalytic domain. Insights into substrate-induced enzymatic activation of MKP.

  2003cited by this paper
• Dual-specificity phosphatase Pyst2-L is constitutively highly expressed in myeloid leukemia and other malignant cells

  2003cited by this paper
• Redox regulation of protein tyrosine phosphatase 1B involves a sulphenyl-amide intermediate

  2003cited by this paper
• JNK phosphorylates paxillin and regulates cell migration

  2003cited by this paper
• Extracellular signal-regulated kinase 2 is necessary for mesoderm differentiation

  2003cited by this paper
• Fidelity and spatio-temporal control in MAP kinase (ERKs) signalling.

  2003cited by this paper
• Cross-talk between JNK/SAPK and ERK/MAPK Pathways

  2003cited by this paper
• p38 MAP kinases: key signalling molecules as therapeutic targets for inflammatory diseases

  2003cited by this paper
• Essential role for ERK2 mitogen‐activated protein kinase in placental development

  2003cited by this paper
• Overexpression of the dual-specificity MAPK phosphatase PYST2 in acute leukemia.

  2003cited by this paper
• Macrophage Apoptosis by Anthrax Lethal Factor Through p38 MAP Kinase Inhibition

  2002cited by this paper
• Dual-specificity phosphatases as targets for antineoplastic agents

  2002cited by this paper
• A central role for JNK in obesity and insulin resistance

  2002cited by this paper
• MAP kinases in the immune response.

  2002cited by this paper
• CL100 expression is down-regulated in advanced epithelial ovarian cancer and its re-expression decreases its malignant potential

  2002cited by this paper
• MAP kinase phosphatases

  2002cited by this paper
• MAP Kinase Phosphatase As a Locus of Flexibility in a Mitogen-Activated Protein Kinase Signaling Network

  2002cited by this paper
• Reversible oxidation and inactivation of protein tyrosine phosphatases in vivo.

  2002cited by this paper
• Molecular interpretation of ERK signal duration by immediate early gene products

  2002cited by this paper
• Scaffold Role of a Mitogen-activated Protein Kinase Phosphatase, SKRP1, for the JNK Signaling Pathway*

  2002cited by this paper
• Knockout of ERK1 MAP kinase enhances synaptic plasticity in the striatum and facilitates striatal-mediated learning and memory.

  2002cited by this paper
• 4‐Isoavenaciolide covalently binds and inhibits VHR, a dual‐specificity phosphatase

  2002cited by this paper
• Dexamethasone Causes Sustained Expression of Mitogen-Activated Protein Kinase (MAPK) Phosphatase 1 and Phosphatase-Mediated Inhibition of MAPK p38

  2002cited by this paper
• Transcription: MAPK-regulated transcription: a continuously variable gene switch?

  2002cited by this paper
• Modular Structure of a Docking Surface on MAPK Phosphatases*

  2002cited by this paper
• Hydrogen peroxide as second messenger in lymphocyte activation

  2002cited by this paper
• Mitogen-Activated Protein Kinase Pathways Mediated by ERK, JNK, and p38 Protein Kinases

  2002cited by this paper
• A Novel Dual Specificity Phosphatase SKRP1 Interacts with the MAPK Kinase MKK7 and Inactivates the JNK MAPK Pathway

  2002cited by this paper
• Cross-talk between ERK and p38 MAPK mediates selective suppression of pro-inflammatory cytokines by transforming growth factor-beta.

  2002cited by this paper
• The Dual Specificity JKAP Specifically Activates the c-Jun N-terminal Kinase Pathway*

  2002cited by this paper
• Cross-talk between ERK and p38 MAPK Mediates Selective Suppression of Pro-inflammatory Cytokines by Transforming Growth Factor-β*

  2002cited by this paper
• Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions.

  2001cited by this paper
• The nucleus, a site for signal termination by sequestration and inactivation of p42/p44 MAP kinases.

  2001cited by this paper
• Mitogen-Activated Protein Kinase p38 Controls the Expression and Posttranslational Modification of Tristetraprolin, a Regulator of Tumor Necrosis Factor Alpha mRNA Stability

  2001cited by this paper
• Identification and allelic frequencies of novel single-nucleotide polymorphisms in the DUSP1 and BTG1 genes

  2001cited by this paper
• Solution structure of ERK2 binding domain of MAPK phosphatase MKP-3: structural insights into MKP-3 activation by ERK2.

  2001cited by this paper
• Activation of the Jnk signaling pathway by a dual-specificity phosphatase, JSP-1

  2001cited by this paper
• Combinatorial control of the specificity of protein tyrosine phosphatases.

  2001cited by this paper
• A Novel MAPK Phosphatase MKP-7 Acts Preferentially on JNK/SAPK and p38α and β MAPKs*

  2001cited by this paper

• DUSP26 protects against acute kidney injury by dephosphorylating p53 at serine 312.

  2026cites this paper
• DUSP7 Overexpression Suppresses Lung Adenocarcinoma Cell Proliferation, Invasion, and M2 Macrophage Polarization Through JAK2/STAT3 Pathway Inhibition

  2026cites this paper
• Integrative analysis of transcriptome dynamics and Notch signaling pathways reveals molecular basis of egg quality in Plectropomus leopardus

  2026cites this paper
• Immune dysregulation triggered by inflammatory cytokines in patients with severe respiratory infections

  2026cites this paper
• Frontiers in fungal phosphatases: molecular diversity, regulatory mechanisms, analytical methodologies, ecological significance, and prospects for sustainable utilization.

  2026cites this paper
• Bta-miR-25 alleviates lipopolysaccharide-induced endometritis in cows by targeting DUSP10 to inhibit MAPK signaling.

  2025cites this paper
• Transcriptome analysis reveals molecular mechanisms for salt tolerance in wheat (Triticum aestivum L.).

  2025cites this paper
• Mechanosensitive genomic enhancers potentiate the cellular response to matrix stiffness.

  2025cites this paper
• Glutamate enhances shrimp antibacterial ability by boosting its cellular immunity

  2025cites this paper
• From injury to recovery: transcriptomic dynamics in zebrafish brain regeneration

  2025cites this paper
• Phosphatases: An undervalued class of antitumor drug targets

  2025cites this paper
• LHPP‐P38 MAPK/ERK‐ETS1 Axis Negative Feedback Signaling Restrains Progression in Breast Cancer

  2025cites this paper
• Dual-specific phosphatase DUSP21 is a novel negative feedback regulator for STAT3.

  2025cites this paper
• Dynamic and structural insights into allosteric regulation on MKP5 a dual-specificity phosphatase

  2025cites this paper
• Hydrogel delivering self-assembled herbal nanoparticles accelerates diabetic wound healing through mitochondrial regulation

  2025cites this paper
• Phosphorylation as a regulatory mechanism of HP1 protein multifunctionality

  2025cites this paper
• DUSP4 inhibited tumor cell proliferation by downregulating glycolysis via p-ERK/p-PGK1 signaling in ovarian cancer

  2025cites this paper
• Cells of the Maternal–Fetal Interface May Contribute to Epidural-Related Maternal Fever After Administration of Ropivacaine: The Role of Phosphatases DUSP9 and PHLPP1

  2025cites this paper
• Discovery of a novel C2-functionalized chromen-4-one scaffold for the development of p38α MAPK signaling inhibitors to mitigate neutrophilic inflammatory responses.

  2025cites this paper
• FGFR antagonists restore defective mandibular bone repair in a mouse model of osteochondrodysplasia

  2025cites this paper
• Integration of urine retinol-binding protein and genetic markers for early prediction of tacrolimus nephrotoxicity using machine learning

  2025cites this paper
• Rhamnose alleviates the proinflammatory response during endotoxemia via the CEACAM1/LGALS9-p38 axis

  2025cites this paper
• Lithocholic acid attenuates DON-induced inflammatory responses via epigenetic regulation of DUSP5 and TRAF5 in porcine intestinal epithelial cells

  2025cites this paper
• Scutellarin Protects Retinal Ganglion Cells in Glaucoma by Targeting the Hsp90aa1-MAPK Pathway to Inhibit Apoptosis

  2025cites this paper
• Lithium partially rescues gene expression and enhancer activity from heterozygous knockout of AKAP11 while inducing novel differential changes

  2025cites this paper
• Integrative Multi-Omic Profiling of the Human Phosphatome Identifies DUSP15 as a Tumour-Selective Regulator of Immune-Metabolic Reprogramming in Chromophobe Renal Cell Carcinoma

  2025cites this paper
• Unveiling the potential of MSC extracellular vesicles: MiR-122-5p enhancing chondrocyte regeneration in osteoarthritis via autophagy mechanism

  2025cites this paper
• Flavescensines A–L: Novel azaspiro[4.4] heterodimeric alkaloids from Sophora flavescens protect against liver injury by inhibiting DUSP2-mediated mitochondrial apoptosis

  2025cites this paper
• Characterization of m6A‐Related Genes in Tumor‐Associated Macrophages for Prognosis, Immunotherapy, and Drug Prediction in Lung Adenocarcinomas Based on Machine Learning Algorithms

  2025cites this paper
• Interferon regulatory factor 3 beyond innate immunity: Regulation in obesity and metabolic disorders.

  2025cites this paper
• Exploring the potential biomarkers between stroke and obstructive sleep apnea by WGCNA and machine learning

  2025cites this paper
• Regulatory roles of MKP7/DUSP16 in cancer

  2025cites this paper
• Disruption of the Clock Component BMAL1 in HDM-induced Asthma Causes GC Resistance in Airway Epithelial Cells by Regulating GR Phosphorylation through the DUSP4-p38MAPK Pathway

  2025cites this paper
• Basal activation of ERK1/2 blunts the antimicrobial activity of neutrophils from aged hosts against antibody opsonized Streptococcus pneumoniae

  2025cites this paper
• A 3D tumor spheroid model with robust T cell infiltration for evaluating immune cell engagers

  2025cites this paper
• Flavonoides en la dieta, perspectivas en la regulación de la inflamación intestinal

  2025cites this paper
• Murine Model Insights: Identifying Dusp15 as a Novel Biomarker for Diabetic Cardiomyopathy Uncovered Through Integrated Omics Analysis and Experimental Validation

  2025cites this paper
• Dual-specific phosphatases-8: a new target for clinical disease intervention

  2025cites this paper
• Spike-in enhanced phosphoproteomics uncovers synergistic signaling responses to MEK inhibition in colon cancer cells

  2024cites this paper
• GR/P300 Regulates MKP1 Signaling Pathway and Mediates Depression-like Behavior in Prenatally Stressed Offspring

  2024cites this paper
• Dynamic and structural insights into allosteric regulation on MKP5 a dual-specificity phosphatase

  2024cites this paper
• Epithelial cells derived exosomal miR-203a-3p facilitates stromal inflammation of type IIIA chronic prostatitis/chronic pelvic pain syndrome by targeting DUSP5 and increasing MCP-1 generation

  2024cites this paper
• Mechanistic Understanding of Dexamethasone-Mediated Protection against Remdesivir-Induced Hepatotoxicity

  2024cites this paper
• DUSP3 modulates IRES‐dependent translation of mRNAs through dephosphorylation of the HNRNPC protein in cells under genotoxic stimulus

  2024cites this paper
• The E3 Ubiquitin Protein Ligase LINCR Amplifies the TLR-Mediated Signals through Direct Degradation of MKP1

  2024cites this paper
• Combined KRAS-MAPK pathway inhibitors and HER2-directed drug conjugate is efficacious in pancreatic cancer

  2024cites this paper
• DUSP22 Ameliorates Endothelial-to-Mesenchymal Transition in HUVECs through Smad2/3 and MAPK Signaling Pathways

  2024cites this paper
• The KLF16/MYC feedback loop is a therapeutic target in bladder cancer

  2024cites this paper
• A blood-based 3-gene signature score for therapeutic monitoring in patients with pulmonary tuberculosis.

  2024cites this paper
• Prenatal Fluoxetine Exposure Influences Glucocorticoid Receptor-Mediated Activity in the Prefrontal Cortex of Adolescent Rats Exposed to Acute Stress.

  2024cites this paper
• Fibroblast growth factors-An introduction to our primer series.

  2024cites this paper
• Mechanosensitive genomic enhancers potentiate the cellular response to matrix stiffness

  2024cites this paper
• Dual specific phosphatase 4 suppresses ferroptosis and enhances sorafenib resistance in hepatocellular carcinoma.

  2024cites this paper
• Enhanced MAPK signaling induced by CSF3R mutants confers dependence to DUSP1 for leukemic transformation

  2024cites this paper
• Differential gene expression patterns in ST-elevation Myocardial Infarction and Non-ST-elevation Myocardial Infarction

  2024cites this paper
• Transcriptomic Response of the Ovarian Follicle Complex in Post-Vitellogenic Rainbow Trout to 17α,20β-Dihdroxy-4-pregnen-3-one In Vitro

  2024cites this paper
• Nr1d1 inhibition mitigates intermittent hypoxia-induced pulmonary hypertension via Dusp1-mediated Erk1/2 deactivation and mitochondrial fission attenuation

  2024cites this paper
• Genome-wide characterization and comparative expression profiling of dual-specificity phosphatase genes in yellow catfish (Pelteobagrus fulvidraco) after infection with exogenous Aeromonas hydrophila

  2024cites this paper
• Framework nucleic acids as promising reactive oxygen species scavengers for anti-inflammatory therapy.

  2024cites this paper
• Suppressing DUSP16 overexpression induced by ELK1 promotes neural progenitor cell differentiation in mouse models of Alzheimer's disease

  2024cites this paper
• The Atypical Dual Specificity Phosphatase DUSP15 Regulates Jak1-Mediated STAT3 Activation.

  2024cites this paper
• Cell–cell communication: new insights and clinical implications

  2024cites this paper
• Unraveling the Genetics of Shared Clinical and Serological Manifestations in Patients With Systemic Inflammatory Autoimmune Diseases

  2024cites this paper
• Directly selecting cell-type marker genes for single-cell clustering analyses

  2024cites this paper
• Fisetin is a selective adenosine triphosphate‐competitive inhibitor for mitogen‐activated protein kinase kinase 4 to inhibit lipopolysaccharide‐stimulated inflammation

  2024cites this paper
• The antisense lncRNA of TAB2 that prevents oxidative stress to enhance the follicular growth in mammals

  2024cites this paper
• Hyperactivation of MEK1 in cortical glutamatergic neurons results in projection axon deficits and aberrant motor learning

  2024cites this paper
• Energy‑stress‑mediated activation of AMPK sensitizes MPS1 kinase inhibition in triple‑negative breast cancer

  2024cites this paper
• Transcriptome profiling of canine parvovirus 2 nonstructural gene 1(CPV2.NS1) transfected 4 T1 mice mammary tumor cells to elucidate its oncolytic effects.

  2024cites this paper
• Integrative function of histone deacetylase 3 in inflammation

  2024cites this paper
• Inhibition of a conserved bacterial dual-specificity phosphatase confers plant tolerance to Candidatus Liberibacter spp

  2024cites this paper
• ASAH1 facilitates TNBC by DUSP5 suppression-driven activation of MAP kinase pathway and represents a therapeutic vulnerability

  2024cites this paper
• Reversible control of kinase signaling through chemical-induced dephosphorylation

  2024cites this paper
• m6A-mediated HDAC9 upregulation promotes particulate matter-induced airway inflammation via epigenetic control of DUSP9-MAPK axis and acts as an inhaled nanotherapeutic target.

  2024cites this paper
• Revealing the Complete Bispecific Phosphatase Genes (DUSPs) across the Genome and Investigating the Expression Patterns of GH_A11G3500 Resistance against Verticillium wilt

  2024cites this paper
• Retinoic acid drives intestine-specific adaptation of effector ILC2s originating from distant sites

  2023cites this paper
• Feto-maternal cholesterol transport regulated by β-Klotho–FGF15 axis is essential for fetal growth

  2023cites this paper
• Delineating the glioblastoma stemness by genes involved in cytoskeletal rearrangements and metabolic alterations

  2023cites this paper
• ADSC secretome constrains NK cell activity by attenuating IL-2-mediated JAK-STAT and AKT signaling pathway via upregulation of CIS and DUSP4

  2023cites this paper
• Directly selecting differentially expressed genes for single-cell clustering analyses

  2023cites this paper
• CD4+ T cells aggravate hemorrhagic brain injury

  2023cites this paper
• Expression of dual-specificity phosphatases in TGFβ1-induced EMT in SKOV3 cells

  2023cites this paper
• Bioinformatic analysis and experimental validation of the potential gene in the airway inflammation of steroid-resistant asthma

  2023cites this paper
• Analysis of post-translational modification dynamics unveiled novel insights into Rice responses to MSP1.

  2023cites this paper
• Loss of SETD2 aggravates colorectal cancer progression caused by SMAD4 deletion through the RAS/ERK signalling pathway

  2023cites this paper
• CHOP promotes coelomocyte apoptosis through p38-MAPK pathway in Vibrio splendidus-challenged sea cucumber Apostichopus japonicus.

  2023cites this paper
• CDC14B is a favorable biomarker for recurrence and prognosis of GBM.

  2023cites this paper
• Dual-specificity phosphatases 22-deficient T cells contribute to the pathogenesis of ankylosing spondylitis

  2023cites this paper
• MAPK Pathways in Ocular Pathophysiology: Potential Therapeutic Drugs and Challenges

  2023cites this paper
• Comprehensive analysis of the FOXA1-related ceRNA network and identification of the MAGI2-AS3/DUSP2 axis as a prognostic biomarker in prostate cancer

  2023cites this paper
• Donor and recipient polymorphisms of MAPK signaling pathway genes influence post-transplant liver function in Chinese liver transplant patients taking tacrolimus.

  2023cites this paper
• Identification of mitogen-activated protein kinase phosphatase-1 (MKP-1) protein partners using tandem affinity purification and mass spectrometry

  2023cites this paper
• The genomic landscape and clonal evolutionary trajectory of classical hairy cell leukemia

  2023cites this paper
• Identification of Genes Involved in EGF-Induced Apoptosis Using CRISPR/Cas9 Knockout Screening: Implications for Novel Therapeutic Targets in EGFR-Overexpressing Cancers

  2023cites this paper
• Molecular Mechanisms Underlying Neuroinflammation Elicited by Occupational Injuries and Toxicants

  2023cites this paper
• Effects of low‐level Er:YAG laser irradiation on proliferation and gene expression in primary gingival fibroblasts isolated from mouse maxilla

  2023cites this paper
• Single-cell transcriptome reveals cell division-regulated hub genes in the unicellular eukaryote Paramecium.

  2023cites this paper
• ARID1A loss activates MAPK signaling via DUSP4 downregulation

  2023cites this paper
• Immunomodulatory effects and mechanisms of Tiepishihu Xiyangshen granules on cyclophosphamide induced immuno-suppression via TLR4/MAPKs and PI3K/AKT/FOXO3a signal pathways.

  2023cites this paper
• Cereblon Deficiency Contributes to the Development of Elastase-Induced Emphysema by Enhancing NF-κB Activation

  2022influential citation