MAP kinase phosphatases

SummaryMitogen-activated protein MAP kinases are key signal-transducing enzymes that are activated by a wide range of extracellular stimuli. They are responsible for the induction of a number of cellular responses, such as changes in gene expression, proliferation, differentiation, cell cycle arrest and apoptosis. Although regulation of MAP kinases by a phosphorylation cascade has long been recognized as significant, their inactivation through the action of specific phosphatases has been less studied. An emerging family of structurally distinct dual-specificity serine, threonine and tyrosine phosphatases that act on MAP kinases consists of ten members in mammals, and members have been found in animals, plants and yeast. Three subgroups have been identified that differ in exon structure, sequence and substrate specificity.

• Publication year

  2002

• Venue

  Genome Biology

• Publication date

  2002-06-26

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1186/gb-2002-3-7-reviews3009PMID 12184814PMCID 139386
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Isolation and characterization of a Drosophila homologue of mitogen-activated protein kinase phosphatase-3 which has a high substrate specificity towards extracellular-signal-regulated kinase.

  2002cited by this paper
• Discordance between the Binding Affinity of Mitogen-activated Protein Kinase Subfamily Members for MAP Kinase Phosphatase-2 and Their Ability to Activate the Phosphatase Catalytically*

  2001cited by this paper
• Docking Sites on Substrate Proteins Direct Extracellular Signal-regulated Kinase to Phosphorylate Specific Residues*

  2001cited by this paper
• Structural organization of the rat mitogen-activated protein kinase phosphatase 2 gene.

  2001cited by this paper
• A Novel Mitogen-Activated Protein Kinase Phosphatase Is an Important Negative Regulator of Lipopolysaccharide-Mediated c-Jun N-Terminal Kinase Activation in Mouse Macrophage Cell Lines

  2001cited by this paper
• A Novel MAPK phosphatase MKP-7 acts preferentially on JNK/SAPK and p38 alpha and beta MAPKs.

  2001cited by this paper
• Mammalian MAP kinase signalling cascades

  2001cited by this paper
• Notch Inhibition of RAS Signaling Through MAP Kinase Phosphatase LIP-1 During C. elegans Vulval Development

  2001cited by this paper
• MKP-7, a Novel Mitogen-activated Protein Kinase Phosphatase, Functions as a Shuttle Protein*

  2001cited by this paper
• Multiple Regions of MAP Kinase Phosphatase 3 Are Involved in Its Recognition and Activation by ERK2*

  2001cited by this paper
• Solution structure of ERK2 binding domain of MAPK phosphatase MKP-3: structural insights into MKP-3 activation by ERK2.

  2001cited by this paper
• Mitogen-activated protein kinase phosphatase is required for genotoxic stress relief in Arabidopsis.

  2001cited by this paper
• A Novel MAPK Phosphatase MKP-7 Acts Preferentially on JNK/SAPK and p38α and β MAPKs*

  2001cited by this paper
• Inhibitory Role for Dual Specificity Phosphatase VHR in T Cell Antigen Receptor and CD28-induced Erk and Jnk Activation*

  2001cited by this paper
• Regulation of Dual-specificity Phosphatases M3/6 and hVH5 by Phorbol Esters

  2000cited by this paper
• Mechanistic Basis for Catalytic Activation of Mitogen-activated Protein Kinase Phosphatase 3 by Extracellular Signal-regulated Kinase*

  2000cited by this paper
• A conserved docking motif in MAP kinases common to substrates, activators and regulators

  2000cited by this paper
• Protein Kinases and Phosphatases in the Drosophila Genome

  2000cited by this paper
• Catalytic activation of mitogen-activated protein (MAP) kinase phosphatase-1 by binding to p38 MAP kinase: critical role of the p38 C-terminal domain in its negative regulation.

  2000cited by this paper
• Compartment-specific regulation of extracellular signal-regulated kinase (ERK) and c-Jun N-terminal kinase (JNK) mitogen-activated protein kinases (MAPKs) by ERK-dependent and non-ERK-dependent inductions of MAPK phosphatase (MKP)-3 and MKP-1 in differentiating P19 cells.

  2000cited by this paper
• Multiple docking sites on substrate proteins form a modular system that mediates recognition by ERK MAP kinase.

  1999cited by this paper
• The protein kinases of Caenorhabditis elegans: a model for signal transduction in multicellular organisms.

  1999cited by this paper
• Extracellular Regulated Kinases (ERK) 1 and ERK2 Are Authentic Substrates for the Dual-specificity Protein-tyrosine Phosphatase VHR

  1999cited by this paper
• Molecular Cloning and Characterization of a Novel Dual Specificity Phosphatase, MKP-5*

  1999cited by this paper
• Crystal structure of the MAPK phosphatase Pyst1 catalytic domain and implications for regulated activation

  1999cited by this paper
• Reduced MAP kinase phosphatase-1 degradation after p42/p44MAPK-dependent phosphorylation.

  1999cited by this paper
• MKP5, a new member of the MAP kinase phosphatase family, which selectively dephosphorylates stress-activated kinases

  1999cited by this paper
• Mitogen-Activated Protein Kinases: Specific Messages from Ubiquitous Messengers

  1999cited by this paper
• Gathering STYX: phosphatase-like form predicts functions for unique protein-interaction domains.

  1998cited by this paper
• Differential targeting of MAP kinases to the ETS‐domain transcription factor Elk‐1

  1998cited by this paper
• Isolation of the human genes encoding the pyst1 and Pyst2 phosphatases: characterisation of Pyst2 as a cytosolic dual-specificity MAP kinase phosphatase and its catalytic activation by both MAP and SAP kinases.

  1998cited by this paper
• puckered encodes a phosphatase that mediates a feedback loop regulating JNK activity during dorsal closure in Drosophila.

  1998cited by this paper
• Signaling pathways in Ras-mediated tumorigenicity and metastasis.

  1998cited by this paper
• Catalytic activation of the phosphatase MKP-3 by ERK2 mitogen-activated protein kinase.

  1998cited by this paper
• Protein tyrosine phosphatases: mechanisms of catalysis and regulation.

  1998cited by this paper
• Molecular Cloning and Functional Characterization of a Novel Mitogen-activated Protein Kinase Phosphatase, MKP-4*

  1997cited by this paper
• Mitogen-activated Protein Kinase Phosphatases Inactivate Stress-activated Protein Kinase Pathways in Vivo*

  1997cited by this paper
• Genomic organization and chromosomal localization of a member of the MAP kinase phosphatase gene family to human chromosome 11p15.5 and a pseudogene to 10q11.2.

  1997cited by this paper
• Chromosomal localization of three human dual specificity phosphatase genes (DUSP4, DUSP6, and DUSP7).

  1997cited by this paper
• A novel human ERK phosphatase regulates H-ras and v-raf signal transduction

  1997cited by this paper
• MKP-3, a Novel Cytosolic Protein-tyrosine Phosphatase That Exemplifies a New Class of Mitogen-activated Protein Kinase Phosphatase (*)

  1996cited by this paper
• PEST sequences and regulation by proteolysis.

  1996cited by this paper
• A Novel Cytoplasmic Dual Specificity Protein Tyrosine Phosphatase Implicated in Muscle and Neuronal Differentiation (*)

  1996cited by this paper
• The Dual Specificity Phosphatases M3/6 and MKP-3 Are Highly Selective for Inactivation of Distinct Mitogen-activated Protein Kinases*

  1996cited by this paper
• Disruption of the erp/mkp-1 gene does not affect mouse development: normal MAP kinase activity in ERP/MKP-1-deficient fibroblasts.

  1996cited by this paper
• Crystal Structure of the Dual Specificity Protein Phosphatase VHR

  1996cited by this paper
• Differential regulation of the MAP, SAP and RK/p38 kinases by Pyst1, a novel cytosolic dual‐specificity phosphatase.

  1996cited by this paper
• A member of the MAP kinase phosphatase gene family in mouse containing a complex trinucleotide repeat in the coding region.

  1996cited by this paper
• The Mitogen-activated Protein Kinase Phosphatases PAC1, MKP-1, and MKP-2 Have Unique Substrate Specificities and Reduced Activity in Vivo toward the ERK2 sevenmaker Mutation (*)

  1996cited by this paper
• Isolation and Characterization of a Novel Dual Specific Phosphatase, HVH2, Which Selectively Dephosphorylates the Mitogen-activated Protein Kinase (*)

  1995cited by this paper
• Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation.

  1995cited by this paper
• Multiple Dual Specificity Protein Tyrosine Phosphatases Are Expressed and Regulated Differentially in Liver Cell Lines (*)

  1995cited by this paper
• Genomic organization and chromosomal localization of the DUSP2 gene, encoding a MAP kinase phosphatase, to human 2p11.2-q11.

  1995cited by this paper
• hVH‐5: A Protein Tyrosine Phosphatase Abundant in Brain that Inactivates Mitogen‐Activated Protein Kinase

  1995cited by this paper
• A Novel Mitogen-activated Protein Kinase Phosphatase. STRUCTURE, EXPRESSION, AND REGULATION (*)

  1995cited by this paper
• Isolation and characterisation of a uniquely regulated threonine, tyrosine phosphatase (TYP 1) which inactivates ERK2 and p54jnk.

  1995cited by this paper
• Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells.

  1994cited by this paper
• Transformation of mammalian cells by constitutively active MAP kinase kinase.

  1994cited by this paper
• Chromosomal localization of four human VH1-like protein-tyrosine phosphatases.

  1994cited by this paper
• CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice.

  1994cited by this paper
• MSG5, a novel protein phosphatase promotes adaptation to pheromone response in S. cerevisiae.

  1994cited by this paper
• Isolation and characterization of a human dual specificity protein-tyrosine phosphatase gene.

  1994cited by this paper
• A novel dual specificity phosphatase induced by serum stimulation and heat shock.

  1994cited by this paper
• Structure, mapping, and expression of erp, a growth factor-inducible gene encoding a nontransmembrane protein tyrosine phosphatase, and effect of ERP on cell growth

  1993cited by this paper
• PAC-1: a mitogen-induced nuclear protein tyrosine phosphatase.

  1993cited by this paper
• Amino acid sequence similarity between CL100, a dual-specificity MAP kinase phosphatase and cdc25.

  1993cited by this paper
• Oxidative stress and heat shock induce a human gene encoding a protein-tyrosine phosphatase

  1992cited by this paper
• cDNA sequence of a growth factor-inducible immediate early gene and characterization of its encoded protein.

  1992cited by this paper
• A Tyr/Ser protein phosphatase encoded by vaccinia virus

  1991cited by this paper

• Narrative review on the development of multi-target pharmacological agents for the management of rheumatoid arthritis

  2026cites this paper
• In Situ H2S-Releasing Stents Optimize Vascular Healing.

  2025cites this paper
• PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and Tamoxifen in a luminal A breast cancer model

  2025cites this paper
• Regulatory roles of MKP7/DUSP16 in cancer

  2025cites this paper
• Dual-specificity protein phosphatase 1: A potential therapeutic target in cancer

  2025cites this paper
• The kinase ATM delays Arabidopsis leaf senescence by stabilizing the phosphatase MKP2 in a phosphorylation-dependent matter.

  2025cites this paper
• Identification of a dual specificity protein phosphatase and its function in regulating innate immune signaling in Crassostrea gigas.

  2025cites this paper
• Transcriptomic analysis of coxsackievirus B3 infection in induced pluripotent stem cell-derived brain-like endothelial cells

  2024influential citation
• Functional Role of DUSP6 in the EGFR-mediated Progression of Head and Neck Squamous Cell Carcinoma

  2024cites this paper
• Endothelial Reactive Oxygen Species: Key Players in Cardiovascular Health and Disease

  2024cites this paper
• MAPK phosphatase 1 inhibition of p38α within lung myofibroblasts is essential for spontaneous fibrosis resolution

  2024cites this paper
• Screening of potential biomarkers of osteoarthritis: a bioinformatics analysis

  2024cites this paper
• DUSP1 Promotes Osimertinib Drug-Tolerant Persistence by Inhibiting MAPK/ERK Signaling in Non-small Cell Lung Cancer

  2024cites this paper
• Identification of key immune‐related genes and immune infiltration in diabetic nephropathy based on machine learning algorithms

  2023cites this paper
• Angelicin inhibits cell growth and promotes apoptosis in oral squamous cell carcinoma by negatively regulating DUSP6/cMYC signaling pathway.

  2023cites this paper
• Epstein-Barr virus-encoded miR-BART11-3p modulates the DUSP6-MAPK axis to promote gastric cancer cell proliferation and metastasis

  2023cites this paper
• [Hsa-miR-148a-3p promotes malignant behavior of breast cancer cells by downregulating DUSP1].

  2023cites this paper
• N6-Methyladenosine and Reader Protein YTHDF2 Enhance the Innate Immune Response by Mediating DUSP1 mRNA Degradation and Activating Mitogen-Activated Protein Kinases during Bacterial and Viral Infections

  2023influential citation
• Combined Aurora Kinase A and CHK1 Inhibition enhances radiosensitivity of triple-negative breast cancer through induction of apoptosis and mitotic catastrophe associated with excessive DNA damage.

  2023cites this paper
• Bone repair and key signalling pathways for cell-based bone regenerative therapy: A review

  2023cites this paper
• Mitogen-Activated Protein Kinase Phosphatases: No Longer Undruggable?

  2023influential citation
• Plumbagin has an inhibitory effect on the growth of TSCC PDX model and it enhances the anticancer efficacy of cisplatin

  2023cites this paper
• RIG-I Promotes Tumorigenesis and Confers Radioresistance of Esophageal Squamous Cell Carcinoma by Regulating DUSP6

  2023cites this paper
• DUSP1 mediates BCG induced apoptosis and inflammatory response in THP-1 cells via MAPKs/NF-κB signaling pathway

  2023cites this paper
• N6-methyladenosine (m6A) and reader protein YTHDF2 enhance innate immune response by mediating DUSP1 mRNA degradation and activating mitogen-activated protein kinases during bacterial and viral infections

  2022influential citation
• Inhibition of DUSP6 Activates Autophagy and Rescues the Retinal Pigment Epithelium in Sodium Iodate-Induced Retinal Degeneration Models In Vivo and In Vitro

  2022cites this paper
• Melatonin promotes the proliferation of primordial germ cell‐like cells derived from porcine skin‐derived stem cells: A mechanistic analysis

  2022cites this paper
• Hyperosmotic stress-induced microtubule disassembly in Chlamydomonas reinhardtii

  2022cites this paper
• T cell receptor signaling in the differentiation and plasticity of CD4+ T cells.

  2022cites this paper
• Effect of miR-101 on the Proliferation and Apoptosis of Goat Hair Follicle Stem Cells

  2022cites this paper
• Journal Pre-proof A site on dual-specificity phosphatase MKP7/DUSP16 is required for catalysis and MAPK binding

  2022cites this paper
• Anp32a Promotes Neuronal Regeneration after Spinal Cord Injury of Zebrafish Embryos

  2022cites this paper
• Investigating the Role of DUSP4 in Uveal Melanoma

  2022cites this paper
• Deciphering the Role of Protein Phosphatases in Apicomplexa: The Future of Innovative Therapeutics?

  2022cites this paper
• Molecular target therapeutics of EGF-TKI and downstream signaling pathways in non-small cell lung cancers

  2022cites this paper
• A novel site on dual-specificity phosphatase MKP7/DUSP16 is required for catalysis and MAPK binding

  2022cites this paper
• Hyperosmotic stress-induced microtubule disassembly in Chlamydomonas reinhardtii

  2022cites this paper
• β2-Adrenoceptor Agonists Promote Extracellular Signal-Regulated Kinase 1/2 Dephosphorylation in Human Airway Epithelial Cells by Canonical, cAMP-Driven Signaling Independently of β-Arrestin 2

  2021influential citation
• DUSP9, a Dual-Specificity Phosphatase with a Key Role in Cell Biology and Human Diseases

  2021cites this paper
• The Therapeutic Potential of MAPK/ERK Inhibitors in the Treatment of Colorectal Cancer.

  2021cites this paper
• DUSP1 overexpression attenuates renal tubular mitochondrial dysfunction by restoring Parkin-mediated mitophagy in diabetic nephropathy.

  2021cites this paper
• Upregulation of DUSP6 impairs infectious bronchitis virus replication by negatively regulating ERK pathway and promoting apoptosis

  2021cites this paper
• Siglec-15 Promotes Tumor Progression in Osteosarcoma via DUSP1/MAPK Pathway

  2021cites this paper
• b 2 -Adrenoceptor Agonists Promote Extracellular Signal-Regulated Kinase 1/2 Dephosphorylation in Human Airway Epithelial Cells by Canonical, cAMP-Driven Signaling Independently of b -Arrestin 2 S

  2021cites this paper
• A dual-specificity phosphatase, MAP kinase phosphatase 1, positively regulates blue light-mediated seedling development in Arabidopsis

  2021cites this paper
• Role of Protein Tyrosine Phosphatase in Regulation of Cell Signaling Cascades Affecting Tumor Cell Growth: A Future Perspective as Anti- Cancer Drug Target.

  2021cites this paper
• Role of microRNAs in neuroendocrine neoplasms of the stomach

  2020cites this paper
• Inhibition of Protein Phosphatase Methylesterase 1 Dysregulates MAP Kinase Signaling and Attenuates Muscle Cell Differentiation.

  2020cites this paper
• DUSP9 Suppresses Proliferation and Migration of Clear Cell Renal Cell Carcinoma via the mTOR Pathway

  2020cites this paper
• Overexpression of DUSP6 enhances chemotherapy-resistance of ovarian epithelial cancer by regulating the ERK signaling pathway

  2020cites this paper
• LncRNA ROR1-AS1 promotes colon cancer cell proliferation by suppressing the expression of DUSP5/CDKN1A.

  2020cites this paper
• Transcriptome Profiling Reveals New Insights into the Immune Microenvironment and Upregulation of Novel Biomarkers in Metastatic Uveal Melanoma

  2020cites this paper
• DUSP9 Suppresses Proliferation and Migration of Clear Cell Renal Cell Carcinoma via the mTOR Pathway

  2020cites this paper
• DUSP5 suppresses interleukin-1β-induced chondrocyte inflammation and ameliorates osteoarthritis in rats

  2020cites this paper
• Exosome–transmitted microRNA‐133b inhibited bladder cancer proliferation by upregulating dual‐specificity protein phosphatase 1

  2020cites this paper
• Pseudophosphatase MK‐STYX: the atypical member of the MAP kinase phosphatases

  2020cites this paper
• DUSP9-mediated reduction of pERK1/2 supports cancer stem cell-like traits and promotes triple negative breast cancer.

  2020cites this paper
• Dual-specificity MAP kinase phosphatases in health and disease

  2019cites this paper
• Scattered DUSP28 is a novel biomarker responsible for aggravating malignancy via the autocrine and paracrine signaling in metastatic pancreatic cancer.

  2019cites this paper
• Concordant expression pattern across multiple immune tissues of commercial broilers in response to avian pathogenic Escherichia coli (APEC)

  2019cites this paper
• Title Protein tyrosine phosphatase receptor type R is required for Purkinje cell responsiveness in cerebellar long-term depression

  2019cites this paper
• Discovery and Characterization of Halogenated Xanthene Inhibitors of DUSP5 as Potential Photodynamic Therapeutics.

  2019cites this paper
• Eosinophil Activation by Toll-Like Receptor 4 Ligands Regulates Macrophage Polarization

  2019cites this paper
• Dusp8 affects hippocampal size and behavior in mice and humans

  2019cites this paper
• DUSP1/MKP‐1 regulates proliferation and apoptosis in keratinocytes through the ERK/Elk‐1/Egr‐1 signaling pathway

  2019cites this paper
• Phosphorylation Dynamics of JNK Signaling: Effects of Dual-Specificity Phosphatases (DUSPs) on the JNK Pathway

  2019cites this paper
• Hypoxia-inducible factors promote breast cancer stem cell specification and maintenance in response to hypoxia or cytotoxic chemotherapy.

  2019cites this paper
• p 38-MAP Kinase Negatively Regulates the Slow Force Response to Stretch in Rat Myocardium through the Up-Regulation of Dual Specificity Phosphatase 6 ( DUSP 6 )

  2019cites this paper
• Activation of GPR40 produces mechanical antiallodynia via the spinal glial interleukin-10/β-endorphin pathway

  2019cites this paper
• DUSP8 phosphatase: structure, functions, expression regulation and the role in human diseases

  2019cites this paper
• New molecular insights on the response of the green alga Tetraselmis suecica to nitrogen starvation

  2019cites this paper
• Modulation of dopamine D1 receptors via histamine H3 receptors is a novel therapeutic target for Huntington's disease

  2019cites this paper
• Development of Unconventional T Cells Controlled by MicroRNA

  2019cites this paper
• Short-term high-fat meal intake alters the expression of circadian clock-, inflammation-, and oxidative stress-related genes in human skeletal muscle

  2019cites this paper
• Hyperactivation of ERK by multiple mechanisms is toxic to RTK-RAS mutation-driven lung adenocarcinoma cells

  2018cites this paper
• MAP KINASE PHOSPHATASE1 Controls Cell Fate Transition during Stomatal Development[OPEN]

  2018cites this paper
• PHAP1 promotes glioma cell proliferation by regulating the Akt/p27/stathmin pathway

  2018cites this paper
• miR-106a Reduces 5-Fluorouracil (5-FU) Sensitivity of Colorectal Cancer by Targeting Dual-Specificity Phosphatases 2 (DUSP2)

  2018cites this paper
• P68 RNA helicase promotes invasion of glioma cells through negatively regulating DUSP5

  2018cites this paper
• DUSP1 induces apatinib resistance by activating the MAPK pathway in gastric cancer

  2018cites this paper
• Elucidating oncogenic mechanisms in human B cell malignancies

  2018cites this paper
• DUSP28 is a novel biomarker responsible for aggravating malignancy via the autocrine signaling pathways in metastatic pancreatic cancer

  2018cites this paper
• Hsa-miR-202-3p, up-regulated in type 1 gastric neuroendocrine neoplasms, may target DUSP1

  2018cites this paper
• Investigation for the mechanism of quinolone antibacterial agent ofloxacin-induced chondrotoxicity in juvenile rats [an abstract of dissertation and a summary of dissertation review]. 論文内容の要旨

  2018cites this paper
• Dual-specificity phosphatase 6 (DUSP6): a review of its molecular characteristics and clinical relevance in cancer

  2018cites this paper
• Regulatory mechanisms in T cell receptor signalling

  2018cites this paper
• Emerging role of the Jun N‐terminal kinase interactome in human health

  2018influential citation
• The role of C1q as the ligand of discoidin domain receptor 2

  2018cites this paper
• ANP32A regulates ATM expression and prevents oxidative stress in cartilage, brain, and bone

  2018cites this paper
• Luteolin induces apoptosis in vitro through suppressing the MAPK and PI3K signaling pathways in gastric cancer

  2017cites this paper
• Up-regulation of miR-324 suppresses cell apoptosis by targeting DUSP 1 in hepatocellular carcinoma

  2017cites this paper
• Molecular and enzymatic approach to study Trichoderma harzianum-induced disease resistance in Brassica juncea against Albugo candida

  2017cites this paper
• Bone marrow transplantation in mice as a tool to study M2 macrophage activation in atherogenesis

  2017cites this paper
• Effects of Anti-Inflammatory Medications in Patients With Coronary Artery Disease: A Focus on Losmapimod

  2017cites this paper
• Salidroside pretreatment attenuates apoptosis and autophagy during hepatic ischemia–reperfusion injury by inhibiting the mitogen-activated protein kinase pathway in mice

  2017cites this paper
• Study of Cell Viability and JNK / SAPK Level Following Abiotic Stresses (Heat & Radiation) in Breast Cancer Cells

  2017cites this paper
• Effects of deoxynivalenol and deepoxy-deoxynivalenol on bovine ovarian theca cell function

  2017cites this paper
• Identification and functional analysis of dual‐specificity MAP kinase phosphatase 6 gene (dusp6) in response to immune challenges in Japanese flounder Paralichthys olivaceus

  2017cites this paper
• Human Protein Kinases and Obesity.

  2017cites this paper
• Dusp16 Deficiency Causes Congenital Obstructive Hydrocephalus and Brain Overgrowth by Expansion of the Neural Progenitor Pool

  2017cites this paper