Drug interaction with hepatic microsomal cytochrome.

The addition to liver microsomes of various substrates, such as hexobarbital, aminopyrine, or aniline, causes two types of spectral changes. Spectrophotometric studies suggest that these changes are related to substrate interaction with a microsomal hemoprotein. On the basis of these observations, two hypotheses are suggested to explain the interaction of substrates with the liver microsomal mixed function oxidase system.

• Publication year

  1966

• Venue

  Molecular Pharmacology

• Publication date

  1966-04-01

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1016/s0026-895x(25)14752-4PMID 5905665
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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