MPTP induces dystonia and parkinsonism

No abstract is available for this paper.

• Publication year

  1997

• Venue

  Neurology

• Publication date

  1997-11-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1212/WNL.49.5.1432PMID 9371934
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Acute dystonia induced by neuroleptic drugs

  2004cited by this paper
• PET Measurement of Dopamine D2 Receptor-Mediated Changes in Striatopallidal Function

  1997cited by this paper
• Decreased [18F]Spiperone Binding in Putamen in Idiopathic Focal Dystonia

  1997cited by this paper
• Levodopa-induced dyskinesias improved by a glutamate antagonist in Parkinsonian monkeys.

  1996cited by this paper
• Levodopa‐induced dyskinesias improved by a glutamate antagonist in parkinsonia monkeys

  1996cited by this paper
• The basal ganglia: focused selection and inhibition of competing motor programs.

  1996cited by this paper
• Dynamic Changes in Striatal Dopamine D2 and D3 Receptor Protein and mRNA in Response to 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine (MPTP) Denervation in Baboons

  1996cited by this paper
• Hemiatrophy, juvenile‐onset exertional alternating leg paresis, hypotonia, and hemidystonia and adult‐onset hemiparkinsonism: The spectrum of hemiparkinsonism‐hemiatrophy syndrome

  1995cited by this paper
• Recessively inherited L-DOPA-responsive dystonia caused by a point mutation (Q381K) in the tyrosine hydroxylase gene.

  1995cited by this paper
• Induction of rapid eye movement sleep by the microinjection of nerve growth factor into the pontine reticular formation of the cat.

  1995cited by this paper
• D1-D2 dopamine receptor synergy in striatum: effects of intrastriatal infusions of dopamine agonists and antagonists on immediate early gene expression.

  1995cited by this paper
• Dopa-responsive dystonia.

  1995cited by this paper
• The behavioural and motor consequences of focal lesions of the basal ganglia in man.

  1994cited by this paper
• Lessons from a remarkable family with dopa-responsive dystonia.

  1994cited by this paper
• Antiparkinsonian effects of remacemide hydrochloride, a glutamate antagonist, in rodent and primate models of Parkinson's disease

  1994cited by this paper
• A study of idiopathic torsion dystonia in a non‐Jewish family

  1994cited by this paper
• Abnormal cortical responses in patients with writer's cramp

  1993cited by this paper
• Striatal [18F]dopa uptake in familial idiopathic dystonia.

  1993cited by this paper
• Functional mapping of brain areas implicated in auditory--verbal memory function.

  1993cited by this paper
• Meige's syndrome.

  1993cited by this paper
• Basal ganglia intrinsic circuits and their role in behavior.

  1993cited by this paper
• The neostriatal mosaic: multiple levels of compartmental organization.

  1992cited by this paper
• The neostriatal mosaic: multiple levels of compartmental organization.

  1992cited by this paper
• Dystonia induced by combined treatment with L‐dopa and MK‐801 in parkinsonian monkeys

  1992cited by this paper
• Non-steady-state measurement of in vivo radioligand binding with positron emission tomography: specificity analysis and comparison with in vitro binding

  1991cited by this paper
• Dopa‐responsive dystonia

  1991cited by this paper
• Lack of proconvulsant action of GABA depletion in substantia nigra in several seizure models.

  1991cited by this paper
• Abnormal spontaneous activity of globus pallidus neurons in monkeys with MPTP-induced parkinsonism.

  1991cited by this paper
• Dopamine differentially regulates dynorphin, substance P, and enkephalin expression in striatal neurons: in situ hybridization histochemical analysis

  1991cited by this paper
• Functional architecture of basal ganglia circuits: neural substrates of parallel processing.

  1990cited by this paper
• Local cerebral glucose utilization in monkeys with hemiparkinsonism induced by intracarotid infusion of the neurotoxin MPTP

  1990cited by this paper
• D1 and D2 dopamine receptor-regulated gene expression of striatonigral and striatopallidal neurons.

  1990cited by this paper
• The human genome map 1990.

  1990cited by this paper
• Intracarotid 1‐Methyl‐4‐Phenyl‐1,2,3,6‐Tetrahydropyridine Administration: Biochemical and Behavioral Observations in a Primate Model of Hemiparkinsonism

  1990cited by this paper
• Neural mechanisms of dystonia: Evidence from a 2‐deoxyglucose uptake study in a primate model of dopamine agonist‐induced dystonia

  1990cited by this paper
• Abnormal vibration-induced cerebral blood flow responses in idiopathic dystonia.

  1990cited by this paper
• Degradation of Thyrotropin‐Releasing Hormone and Luteinising Hormone‐Releasing Hormone by Enzymes of Brain Tissue

  1990cited by this paper
• The history of veterinary medicine in Alabama, 1892-1952.

  1990cited by this paper
• The functional anatomy of basal ganglia disorders.

  1989cited by this paper
• The dopamine motor system

  1989cited by this paper
• How many kinds of nicotinic acetylcholine receptor are there?

  1989cited by this paper
• Concept and classification of dystonia.

  1988cited by this paper
• Brain neurotransmitters in dystonia musculorum deformans.

  1986cited by this paper
• Hemiparkinsonism in a monkey after unilateral internal carotid artery infusion of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) is associated with regional ipsilateral changes in striatal dopamine D-2 receptor density.

  1986cited by this paper
• Locus ceruleus lesions and eosinophilic inclusions in MPTP‐treated monkeys

  1986cited by this paper
• Hemiparkinsonism in monkeys after unilateral internal carotid artery infusion of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).

  1986cited by this paper
• Permanent human parkinsonism due to 1‐methy 1–4‐phenyl‐1,2,3,6‐tetrahydropyridine (MPTP)

  1985cited by this paper
• A primate model of parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.

  1983cited by this paper
• Writers' cramp-a focal dystonia.

  1982cited by this paper
• Dopamine metabolism following irreversible inactivation of aromatic amino acid decarboxylase in retina

  1981cited by this paper
• Neuroleptic‐induced acute dystonic reactions may be due to enhanced dopamine release on to supersensitive postsynaptic receptors

  1981cited by this paper
• Meige's Syndrome

  1980cited by this paper
• Dystonic reactions following neuroleptics: Time Course and proposed mechanisms

  1976cited by this paper

• Brain network pathophysiology in dystonia

  2026influential citation
• Neuroscience of Human Ventral Lateral (VL) Thalamic Nucleus Related to Movement and Movement Disorders.

  2025cites this paper
• The Second Hit Hypothesis in Animal and Human Dystonia: The Role of Peripheral Nerve Trauma and Spinal Cord Injury

  2025cites this paper
• Dual sensing of hypochlorite and aluminium in plant tissues by a selective diimine-based chemosensor

  2024cites this paper
• Unraveling dystonia circuitry in rodent models using novel neuromodulation techniques

  2024cites this paper
• Transient dystonia correlates with parkinsonism after 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine in nonhuman primates

  2023influential citation
• Bradykinesia and dystonia

  2023cites this paper
• Endocytosis of dopamine receptor: Signaling in brain.

  2023cites this paper
• Carbazole-based Schiff base: A sensitive fluorescent ‘turn-on’ chemosensor for recognition of Al(III) ions in aqueous-alcohol media

  2022cites this paper
• Recent advancement on chromo-fluorogenic sensing of aluminum(III) with Schiff bases

  2022cites this paper
• Simultaneous visual and spectroscopic multi-analyte detection of Al3+ and AsO2- using simple salicylidene based D-π-A chromophore

  2022cites this paper
• Clinical spectrum and management of dystonia in patients with Japanese encephalitis: A systematic review

  2022cites this paper
• Development of parkinsonism after long-standing cervical dystonia - A cohort.

  2021cites this paper
• Emerging concepts on bradykinesia in non‐parkinsonian conditions

  2021cites this paper
• Impact of fatty acid-binding proteins and dopamine receptors on α-synucleinopathy.

  2021cites this paper
• Degradation of Tyrosine Hydroxylase by the Ubiquitin-Proteasome System in the Pathogenesis of Parkinson’s Disease and Dopa-Responsive Dystonia

  2020cites this paper
• Highly chemoselective turn-on fluorescent probe for ferrous (Fe2+) ion detection in cosmetics and live cells.

  2020cites this paper
• Rapid and high yield synthesis of carbon dots with chelating ability derived from acrylamide/chitosan for selective detection of ferrous ions

  2019cites this paper
• A simple, highly selective and ultra-sensitive “off-on-off” fluorescent chemosensor for successive detection of aluminum ion and phosphate in water samples

  2019cites this paper
• Neurobiology of Disease Dystonia and Parkinson's disease: What is the relationship?

  2019cites this paper
• A Highly Selective and Sensitive Fluorescent Chemosensor for Detecting Al3+ Ion in Aqueous Solution and Plant Systems

  2019cites this paper
• Promotional effect of macrocyclization in O2Nx naphtha-aza-crown macrocyclic ligands on fluorescence chemosensing of Al(III)

  2019cites this paper
• Ferrocene appended fluorescein-based ratiomeric fluorescence and electrochemical chemosensor for Fe3+ and Hg2+ ions in aqueous media: Application in real samples analysis

  2019cites this paper
• Oral Pharmacotherapy for Benign Essential Blepharospasm

  2018cites this paper
• Basic and Translational Neuroscience of Childhood-Onset Dystonia: A Control-Theory Perspective.

  2018cites this paper
• Validation of diffusion tensor imaging measures of nigrostriatal neurons in macaques

  2018cites this paper
• Naphthalene based fluorescent chemosensor for Fe2+-ion detection in microbes and real water samples

  2017cites this paper
• Thiophene and diethylaminophenol-based "turn-on" fluorescence chemosensor for detection of Al3+ and F- in a near-perfect aqueous solution

  2017cites this paper
• An Efficient Molecular Tool with Ferrocene Backbone: Discriminating Fe3+ from Fe2+ in Aqueous Media

  2017cites this paper
• The Anatomical Basis for Dystonia: The Motor Network Model

  2017cites this paper
• Mild parkinsonian features in dystonia: Literature review, mechanisms and clinical perspectives.

  2017cites this paper
• Parkinsonism and dystonia are differentially induced by modulation of different territories in the basal ganglia.

  2017cites this paper
• Research Priorities in Limb and Task-Specific Dystonias

  2017cites this paper
• Fluorescent sensing of Al3+ by benzophenone based Schiff base chemosensor and live cell imaging applications: Impact of keto-enol tautomerism

  2017cites this paper
• Solvent-dependent fluorescent-colorimetric probe for dual monitoring of Al(3+) and Cu(2+) in aqueous solution: an application to bio-imaging.

  2016cites this paper
• Deep Brain Stimulation for Movement Disorders of Basal Ganglia Origin: Restoring Function or Functionality?

  2016cites this paper
• Chapter 11 – Dystonia

  2016cites this paper
• Postural & striatal deformities in Parkinson's disease: Are these rare?

  2016cites this paper
• A Novel Animal Model for Investigating the Neural Basis of Focal Dystonia

  2016cites this paper
• Turn-on and reversible luminescent sensor for selective recognition of Al3+ using naphthol hydrazone

  2016cites this paper
• A reversible fluorescent-colorimetric imino-pyridyl bis-Schiff base sensor for expeditious detection of Al(3+) and HSO3(-) in aqueous media.

  2015cites this paper
• Multiple target chemosensor: a fluorescent sensor for Zn(II) and Al(III) and a chromogenic sensor for Fe(II) and Fe(III)

  2015cites this paper
• Striatal cholinergic dysfunction as a unifying theme in the pathophysiology of dystonia.

  2015cites this paper
• A selective colorimetric and ratiometric fluorescent chemosensor for detection of Al3+ ion

  2015cites this paper
• Benign Essential Blepharospasm is a Disorder of Neuroplasticity: Lessons From Animal Models.

  2015cites this paper
• A new bifunctional Schiff base as a colorimetric and fluorescence sensor for Al3+ and CN−

  2015cites this paper
• Genetic and neuropathological study of primary and secondary dystonic syndromes

  2015cites this paper
• Chapter 26 – Animal Models of Focal Dystonia

  2015cites this paper
• Preserved dichotomy but highly irregular and burst discharge in the basal ganglia in alert dystonic rats at rest.

  2015cites this paper
• Neuroimaging Analysis of the Dopamine Basis for Apathetic Behaviors in an MPTP-Lesioned Primate Model

  2015cites this paper
• The Role of Dopamine and Dopaminergic Pathways in Dystonia: Insights from Neuroimaging

  2015cites this paper
• Interaction of a Schiff-base fluorescent sensor with Al3+: experimental and computational studies

  2014cites this paper
• A Quinoline Derivative as an Efficient Sensor to Detect Selectively Al3+ ion

  2014cites this paper
• A highly selective fluorescence turn-on and reversible sensor for Al3 + ion

  2014cites this paper
• Risk factors for idiopathic dystonia in Queensland, Australia.

  2014cites this paper
• Synthesis, characterization and electronic effects investigations of new 5,7-disubstituted tris(8-quinolinolate)Al(III) complexes

  2014cites this paper
• Neuroimaging biomarkers for Parkinson disease: Facts and fantasy

  2014cites this paper
• Spatial Reorganization of Putaminal Dopamine D2-Like Receptors in Cranial and Hand Dystonia

  2014cites this paper
• In vivo measures of nigrostriatal neuronal response to unilateral MPTP treatment.

  2014cites this paper
• The focal dystonias: Current views and challenges for future research

  2013cites this paper
• Validation of nigrostriatal positron emission tomography measures: Critical limits

  2013cites this paper
• A turn-on and reversible Schiff-base fluorescence sensor for Al3 + ion

  2013cites this paper
• A turn-on and reversible Schiff base fluorescence sensor for Al3+ ion.

  2013cites this paper
• Striatal dopaminergic dysfunction at rest and during task performance in writer's cramp.

  2013cites this paper
• Validation of midbrain positron emission tomography measures for nigrostriatal neurons in macaques

  2013cites this paper
• Animal Models for Investigating Benign Essential Blepharospasm

  2013cites this paper
• Animal models for dystonia

  2013cites this paper
• Deep brain stimulation: how does it work?

  2013cites this paper
• The anatomical basis of dystonia: Current view using neuroimaging

  2013cites this paper
• A turn-on and reversible fluorescence sensor for zinc ion.

  2012cites this paper
• Changes in basal ganglia processing of cortical input following magnetic stimulation in Parkinsonism.

  2012cites this paper
• Low nigrostriatal reserve for motor parkinsonism in nonhuman primates.

  2012cites this paper
• No Differential Regulation of Dopamine Transporter (DAT) and Vesicular Monoamine Transporter 2 (VMAT2) Binding in a Primate Model of Parkinson Disease

  2012cites this paper
• Dopamine pathway loss in nucleus accumbens and ventral tegmental area predicts apathetic behavior in MPTP-lesioned monkeys.

  2012cites this paper
• A turn-on and reversible fluorescence sensor for Al3+ ion.

  2012cites this paper
• Review and update of involuntary facial movement disorders presenting in the ophthalmological setting.

  2011cites this paper
• Multi-Neuronal Recordings in the Basal Ganglia in Normal and Dystonic Rats

  2011cites this paper
• Chapter 12 – Dystonia: Phenomenology, classification, etiology, pathology, biochemistry, and genetics

  2011cites this paper
• Rationale for Surgical Interventions in Movement Disorders

  2011cites this paper
• Decreased striatal dopamine receptor binding in primary focal dystonia: A D2 or D3 defect?

  2011cites this paper
• The functional neuroanatomy of dystonia.

  2011cites this paper
• dtorsin, the Drosophila Ortholog of the Early-Onset Dystonia TOR1A (DYT1), Plays a Novel Role in Dopamine Metabolism

  2011cites this paper
• Deep-Brain Stimulation for Basal Ganglia Disorders.

  2011cites this paper
• Dopamine D2 receptor dysfunction is rescued by adenosine A2A receptor antagonism in a model of DYT1 dystonia.

  2010cites this paper
• Hyperactive putamen in patients with paroxysmal kinesigenic choreoathetosis: A resting‐state functional magnetic resonance imaging study

  2010cites this paper
• Electrophysiological Analysis in an Animal Model of Dystonia

  2010cites this paper
• Functional effects of transcranial direct stimulation in musicians with focal dystonia

  2010cites this paper
• Convergent evidence for abnormal striatal synaptic plasticity in dystonia.

  2010influential citation
• Dysregulation of striatal dopamine release in a mouse model of dystonia

  2010cites this paper
• Primate models of dystonia.

  2009cites this paper
• Hyperbranched calixarenes: synthesis and applications as fluorescent probes.

  2009cites this paper
• Objective quantification of arm rigidity in MPTP-treated primates.

  2009cites this paper
• The subthalamic nucleus in primary dystonia: single-unit discharge characteristics.

  2009influential citation
• Neuroimaging in Baboons

  2009cites this paper
• La disfunzione del recettore striatale D2 induce un'alterata trasmissione GABAergica in un modello murino di distonia DYT1

  2009cites this paper
• TorsinA and dystonia: from nuclear envelope to synapse

  2009cites this paper
• Cervical dystonia: unresolved issues and future challenges.

  2008cites this paper
• Task‐specific Dystonias

  2008cites this paper
• Cervical dystonia: etiology and pathophysiology.

  2008cites this paper
• Electromyographic characterization in an animal model of dystonia

  2008cites this paper