Inflammation and cachexia in chronic kidney disease

No abstract is available for this paper.

• Publication year

  2010

• Venue

  Pediatric nephrology (Berlin, West)

• Publication date

  2010-01-29

• Fields of study

  Medicine, Environmental Science

• Identifiers
  DOI 10.1007/s00467-009-1427-zPMID 20111974
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Role of interleukin-6 in the anemia of chronic disease.

  2009cited by this paper
• IL-6 and serum amyloid A synergy mediates angiotensin II-induced muscle wasting.

  2009cited by this paper
• Modulation of melanocortin signaling ameliorates uremic cachexia.

  2008cited by this paper
• Genetic polymorphisms of the RAS-cytokine pathway and chronic kidney disease

  2008cited by this paper
• A proposed nomenclature and diagnostic criteria for protein-energy wasting in acute and chronic kidney disease.

  2008cited by this paper
• Ubiquitin, proteasomes and proteolytic mechanisms activated by kidney disease.

  2008cited by this paper
• Microinflammation and endothelial damage in hemodialysis.

  2008cited by this paper
• Cardiovascular complications of pediatric chronic kidney disease

  2008cited by this paper
• Cholesterol-lowering effect of plant sterols

  2008cited by this paper
• Ghrelin treatment of chronic kidney disease: improvements in lean body mass and cytokine profile.

  2008cited by this paper
• Decreased maximal aerobic capacity in pediatric chronic kidney disease.

  2008cited by this paper
• Adipokines and Gut Hormones in End-Stage Renal Disease

  2007cited by this paper
• Peripheral administration of the melanocortin-4 receptor antagonist NBI-12i ameliorates uremia-associated cachexia in mice.

  2007influential reference
• Cytokine gene polymorphism and progression of renal and cardiovascular diseases.

  2007cited by this paper
• C-reactive protein, inflammatory conditions, and cardiovascular disease risk.

  2007cited by this paper
• Insulin resistance is associated with skeletal muscle protein breakdown in non-diabetic chronic hemodialysis patients.

  2007cited by this paper
• Long-term outcome of chronic dialysis in children

  2006cited by this paper
• Protein degradation by the ubiquitin-proteasome pathway in normal and disease states.

  2006cited by this paper
• Increased arterial stiffness in children on haemodialysis.

  2006cited by this paper
• Lipid metabolism and renal disease.

  2006cited by this paper
• Chronic kidney disease causes defects in signaling through the insulin receptor substrate/phosphatidylinositol 3-kinase/Akt pathway: implications for muscle atrophy.

  2006cited by this paper
• Myostatin and insulin-like growth factors in uremic sarcopenia: the yin and yang in muscle mass regulation.

  2006cited by this paper
• Effect of Modified C-Reactive Protein on Complement Activation: A Possible Complement Regulatory Role of Modified or Monomeric C-Reactive Protein in Atherosclerotic Lesions

  2006cited by this paper
• New insights on inflammation in chronic kidney disease-genetic and non-genetic factors.

  2006cited by this paper
• Work-induced changes in skeletal muscle IGF-1 and myostatin gene expression in uremia.

  2006cited by this paper
• Downregulated CD36 and oxLDL uptake and stimulated ABCA1/G1 and cholesterol efflux as anti-atherosclerotic mechanisms of interleukin-10.

  2006cited by this paper
• Mechanisms of skeletal muscle atrophy

  2006cited by this paper
• Body composition and nutritional intake in children with chronic kidney disease

  2006cited by this paper
• Leptin and inflammation-associated cachexia in chronic kidney disease.

  2006cited by this paper
• Energy homeostasis and cachexia in chronic kidney disease

  2006influential reference
• Associations between renal function, volume status and endotoxaemia in chronic kidney disease patients.

  2006cited by this paper
• Inflammation is associated with increased energy expenditure in patients with chronic kidney disease.

  2005cited by this paper
• Enhanced RAGE-mediated NFκB stimulation in inflamed hemodialysis patients

  2005cited by this paper
• Altered morphologic properties of large arteries in children with chronic renal failure and after renal transplantation.

  2005cited by this paper
• Peroxisome proliferator-activated receptor γ polymorphisms affect systemic inflammation and survival in end-stage renal disease patients starting renal replacement therapy

  2005cited by this paper
• Role of leptin and melanocortin signaling in uremia-associated cachexia.

  2005cited by this paper
• Peroxisome proliferator-activated receptor gamma polymorphisms affect systemic inflammation and survival in end-stage renal disease patients starting renal replacement therapy.

  2005cited by this paper
• IL-10, IL-6, and TNF-alpha: central factors in the altered cytokine network of uremia--the good, the bad, and the ugly.

  2005cited by this paper
• Adipose tissue and its relation to inflammation: the role of adipokines.

  2005cited by this paper
• Enhanced RAGE-mediated NFkappaB stimulation in inflamed hemodialysis patients.

  2005cited by this paper
• Chronic kidney disease and inflammation in pediatric patients: from bench to playground

  2005influential reference
• C-reactive protein and albumin as predictors of all-cause and cardiovascular mortality in chronic kidney disease.

  2005cited by this paper
• Molecular mechanisms involved in muscle wasting in cancer and ageing: cachexia versus sarcopenia.

  2005cited by this paper
• Anatomy and regulation of the central melanocortin system

  2005cited by this paper
• Cardiovascular risk factors in chronic kidney disease.

  2005cited by this paper
• The regulation of feeding and metabolic rate and the prevention of murine cancer cachexia with a small-molecule melanocortin-4 receptor antagonist.

  2005cited by this paper
• Direct comparison of dietary portfolio vs statin on C-reactive protein

  2005cited by this paper
• Signalling links in the liver: knitting SOCS with fat and inflammation.

  2005cited by this paper
• Adipokines in Chronic Kidney Disease — Fat Tissue Gives Nephrologists a Message

  2005cited by this paper
• Anorexia and Cachexia

  2005cited by this paper
• Molecular pathways leading to cancer cachexia.

  2005cited by this paper
• Cytokine gene polymorphisms in hemodialysis patients: association with comorbidity, functionality, and serum albumin.

  2004cited by this paper
• Appetite and inflammation, nutrition, anemia, and clinical outcome in hemodialysis patients.

  2004cited by this paper
• Effect of cancer cachexia on triacylglycerol/fatty acid substrate cycling in white adipose tissue

  2004cited by this paper
• Truncal fat mass as a contributor to inflammation in end-stage renal disease.

  2004cited by this paper
• Myostatin mutation associated with gross muscle hypertrophy in a child.

  2004cited by this paper
• CRP as a mediator of disease.

  2004cited by this paper
• Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy.

  2004cited by this paper
• Human C-Reactive Protein Increases Cerebral Infarct Size after Middle Cerebral Artery Occlusion in Adult Rats

  2004cited by this paper
• Genetic predisposition of the interleukin-6 response to inflammation: implications for a variety of major diseases?

  2004cited by this paper
• C-Reactive Protein Attenuates Endothelial Progenitor Cell Survival, Differentiation, and Function: Further Evidence of a Mechanistic Link Between C-Reactive Protein and Cardiovascular Disease

  2004cited by this paper
• Induction of proteasome expression in skeletal muscle is attenuated by inhibitors of NF-κB activation

  2004cited by this paper
• C-reactive protein and features of the metabolic syndrome in a population-based sample of children and adolescents.

  2004influential reference
• IKKbeta/NF-kappaB activation causes severe muscle wasting in mice.

  2004cited by this paper
• Kidney dysfunction, inflammation, and coronary events: a prospective study.

  2004cited by this paper
• C-reactive protein and other circulating markers of inflammation in the prediction of coronary heart disease.

  2004cited by this paper
• The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors.

  2004cited by this paper
• Activation of caspase-3 is an initial step triggering accelerated muscle proteolysis in catabolic conditions.

  2004cited by this paper
• Resting energy expenditure and subsequent mortality risk in peritoneal dialysis patients.

  2004cited by this paper
• Induction of lipolysis in vitro and loss of body fat in vivo by zinc-alpha2-glycoprotein.

  2004cited by this paper
• Treatment with Fluvastatin Rapidly Modulates, via Different Pathways, and in Dependence on the Baseline Level, Inflammation in Hemodialysis Patients

  2004cited by this paper
• Regulation of muscle mass by myostatin.

  2004cited by this paper
• Exercise Capacity in Pediatric Patients with End-Stage Renal Disease

  2004cited by this paper
• Septicemia in the United States dialysis population, 1991 to 1999.

  2004cited by this paper
• Uremia-associated immune defect: the IL-10-CRP axis.

  2003cited by this paper
• Plasma pentosidine is associated with inflammation and malnutrition in end-stage renal disease patients starting on dialysis therapy.

  2003cited by this paper
• Is a single time point C-reactive protein predictive of outcome in peritoneal dialysis patients?

  2003cited by this paper
• White blood cells as a novel mortality predictor in haemodialysis patients.

  2003cited by this paper
• Association of interleukin-6 -174G/C promoter polymorphism with hypertension and left ventricular hypertrophy in dialysis patients.

  2003cited by this paper
• Effect of malnutrition-inflammation complex syndrome on EPO hyporesponsiveness in maintenance hemodialysis patients.

  2003cited by this paper
• Progression of Chronic Kidney Disease: The Role of Blood Pressure Control, Proteinuria, and Angiotensin-Converting Enzyme Inhibition: A Patient-Level Meta-Analysis

  2003cited by this paper
• C-Reactive Protein Upregulates Angiotensin Type 1 Receptors in Vascular Smooth Muscle

  2003cited by this paper
• Inflammation and nutrition in renal insufficiency.

  2003influential reference
• A novel association between residual renal function and left ventricular hypertrophy in peritoneal dialysis patients.

  2002cited by this paper
• Advanced Coronary and Carotid Arteriopathy in Young Adults With Childhood-Onset Chronic Renal Failure

  2002cited by this paper
• Mortality risk in hemodialysis patients and changes in nutritional indicators: DOPPS.

  2002cited by this paper
• Role of the kidney in perioperative inflammatory responses.

  2002cited by this paper
• Muscle ubiquitin m-rNA levels in patients with end-stage renal disease on maintenance hemodialysis.

  2002cited by this paper
• Cancer Anorexia‐Cachexia Syndrome: Current Issues in Research and Management

  2002cited by this paper
• Effects of simvastatin on high-sensitivity C-reactive protein and serum albumin in hemodialysis patients.

  2002cited by this paper
• HMG-CoA reductase inhibitors are associated with reduced mortality in ESRD patients.

  2002cited by this paper
• Inflammation, Malnutrition and Atherosclerosis in End-Stage Renal Disease: A Global Perspective

  2002cited by this paper
• Tumor Necrosis Factor-regulated Biphasic Activation of NF-κB Is Required for Cytokine-induced Loss of Skeletal Muscle Gene Products*

  2002cited by this paper
• Obesity: Keeping hunger at bay

  2002cited by this paper
• Nutrition in CAPD: serum bicarbonate and the ubiquitin-proteasome system in muscle.

  2002cited by this paper
• The role of uncoupling proteins in pathophysiological states.

  2002cited by this paper
• Carotid intima media thickness and left ventricular changes in children with end-stage renal disease.

  2002cited by this paper
• Clinical and demographic predictors of exercise capacity in end-stage renal disease.

  2002cited by this paper
• The inflammatory reflex

  2002cited by this paper
• Cholesterol catabolism in patients with acute myelogenous leukemia and hypocholesterolemia: suppressed levels of a circulating marker for bile acid synthesis.

  2001cited by this paper

• Increased mortality risk with lower versus higher BMI in older adults with T2DM: a Shanghai diabetes management cohort study

  2026cites this paper
• Combating chronic kidney disease-associated cachexia: A literature review of recent therapeutic approaches

  2025influential citation
• Tumor marker elevations in chronic kidney disease: a retrospective study

  2025cites this paper
• Cistanoside F Ameliorates Lipid Accumulation and Enhances Myogenic Differentiation via AMPK-Dependent Signaling in C2C12 Myotubes

  2025cites this paper
• Characteristics of soybean (Glycine max) protein hydrolysate by bromelain and its effect on inflammation and kidney disorders in gentamicin-induced male Wistar rats

  2025cites this paper
• Pharmacokinetic Implications of Pathophysiological Changes in Cachexia Syndrome: A Scoping Review

  2025cites this paper
• Inspiratory Muscle Training in Patients Living with Chronic Kidney Disease and Receiving Hemodialysis: Meta-Analysis of Randomized Controlled Trials.

  2024cites this paper
• Complement 3a and Complement 5a as Biochemical Markers in Diabetic Nephropathy

  2024cites this paper
• Clotting of the Extracorporeal Circuit in Hemodialysis: Beyond Contact-Activated Coagulation.

  2024cites this paper
• Anatomical and Histological Analyses of Rare Pancake Kidney

  2024cites this paper
• The lived experience of renal cachexia: An interpretive phenomenological analysis

  2024cites this paper
• Regulation of Satellite Cells Functions during Skeletal Muscle Regeneration: A Critical Step in Physiological and Pathological Conditions

  2023cites this paper
• Chronic kidney disease as a predictive factor for poor prognosis in traumatic brain injury among older adults: a case-control study

  2023cites this paper
• The metabolite butyrate produced by gut microbiota inhibits cachexia-associated skeletal muscle atrophy by regulating intestinal barrier function and macrophage polarization.

  2023cites this paper
• Sarcopenia in chronic kidney disease: from bench to bedside

  2023cites this paper
• A network pharmacological-based study of the mechanism of Liuwei Dihuang pill in the treatment of chronic kidney disease

  2023cites this paper
• Exploring systemic inflammation in children with chronic kidney disease: correlates of interleukin 6

  2023cites this paper
• Editorial: Immunology of cachexia

  2023cites this paper
• The association between appendicular skeletal muscle index and bone mineral density in children and adolescents with chronic kidney disease: A cross-sectional study

  2023cites this paper
• Interconnection between Cardiac Cachexia and Heart Failure—Protective Role of Cardiac Obesity

  2022cites this paper
• Renoprotection of Selected Antioxidant-Rich Foods (Water Spinach and Red Grape) and Probiotics in Gentamicin-Induced Nephrotoxicity and Oxidative Stress in Rats

  2022cites this paper
• The Relation of Serum Dehydroepiandrosterone Sulfate Level to Protein Energy Wasting in Hemodialysis Patients

  2022cites this paper
• Chronic Kidney Disease-induced Muscle Atrophy: Molecular Mechanisms and Promising Therapies.

  2022cites this paper
• MG53: A potential therapeutic target for kidney disease

  2022cites this paper
• Metabolic Basis and Pathogenesis of Skeletal Muscle Dysfunction as Cause of Frailty in Chronic Kidney Disease

  2022cites this paper
• Developing an Evidence and Theory Based Multimodal Integrative Intervention for the Management of Renal Cachexia: A Theory of Change

  2022cites this paper
• Exploring the lived experience of renal cachexia for individuals with end-stage renal disease and the interrelated experience of their carers: Study protocol

  2022cites this paper
• Skeletal Muscle and Kidney Crosstalk in Chronic Kidney Disease.

  2022cites this paper
• Factors associated with 1-year changes in serum fibroblast growth factor 23 levels in pediatric patients with chronic kidney disease

  2022cites this paper
• Measurement of renal cortical thickness using ultrasound in normal dogs: a reference range study considering bodyweight and body condition score.

  2022cites this paper
• Impact of Low Hemoglobin on Body Composition, Strength, and Redox Status of Older Hemodialysis Patients Following Resistance Training

  2021cites this paper
• Prevalence and determinants of sarcopenia in Indian patients with chronic kidney disease stage 3 & 4

  2021cites this paper
• Influence of Polyunsaturated Fatty Acid Intake on Kidney Functions of Rats with Chronic Renal Failure

  2021cites this paper
• Sarcopenia in patients with chronic kidney disease: prevalence, pathogenesis and clinical significance

  2021cites this paper
• The interplay of immunology and cachexia in infection and cancer

  2021cites this paper
• Controlled Enteral and Parenteral Nutrition in Children on Dialysis

  2021cites this paper
• Short-term intradialytic NMES targeting muscles of the legs improves the phase angle: A pilot randomized clinical trial.

  2021cites this paper
• Global Deletion of Pannexin 3 Resulting in Accelerated Development of Aging‐Induced Osteoarthritis in Mice

  2021cites this paper
• Formononetin ameliorates muscle atrophy by regulating myostatin‐mediated PI3K/Akt/FoxO3a pathway and satellite cell function in chronic kidney disease

  2021cites this paper
• Association between the uremic toxins indoxyl-sulfate and p-cresyl-sulfate with sarcopenia and malnutrition in elderly patients with advanced chronic kidney disease.

  2021cites this paper
• Cumulative C-Reactive Protein Levels and Progression of Malnutrition in Dialysis Patients: A Longitudinal Study

  2021cites this paper
• Challenges of Maintaining Adequate Health and Well-Being, Growth, Nutrition, and Development in Pediatric Transplant Recipients

  2021cites this paper
• Age‐related decline of interferon‐gamma responses in macrophage impairs satellite cell proliferation and regeneration

  2020cites this paper
• Melanocortin-4 receptor antagonist TCMCB07 ameliorates cancer- and chronic kidney disease-associated cachexia.

  2020cites this paper
• Uremic Toxins and Organ Failure

  2020cites this paper
• Molecular Mechanism of Muscle Wasting in CKD

  2020cites this paper
• Protein Energy Metabolism in Chronic Kidney Disease

  2020cites this paper
• Muscle-bone axis in children with chronic kidney disease: current knowledge and future perspectives

  2020cites this paper
• Body mass index change and estimated glomerular filtration rate decline in a middle-aged population: health check-based cohort in Japan

  2020cites this paper
• Gut bacteria-derived peptidoglycan induces a metabolic syndrome-like phenotype via NF-κB-dependent insulin/PI3K signaling reduction in Drosophila renal system

  2020cites this paper
• Uremic Solutes and Sarcopenia

  2020cites this paper
• Cachexia/Protein energy wasting syndrome in CKD: Causation and treatment

  2019cites this paper
• Mechanisms of GLP-1 receptor-independent renoprotective effects of the dipeptidyl peptidase type 4 inhibitor linagliptin in GLP-1 receptor knockout mice with 5/6 nephrectomy.

  2019cites this paper
• Nutritional challenges across the spectrum of chronic kidney disease

  2019cites this paper
• Is body weight or muscle strength correlated with the Malnutrition Inflammation Score (MIS)? A cross-sectional study in hemodialysis patients.

  2019cites this paper
• Sarcopenia in Chronic Kidney Disease: Factors, Mechanisms, and Therapeutic Interventions.

  2019cites this paper
• Evaluation of Electrolyte Concentration and Pro-Inflammatory and Oxidative Status in Dogs with Advanced Chronic Kidney Disease under Dietary Treatment

  2019cites this paper
• Hypoalbuminemia differently affects the serum bone turnover markers in hemodialysis patients

  2019cites this paper
• Unacylated ghrelin and obestatin in pediatric CKD: are they important in protein energy wasting?

  2018cites this paper
• Muscle wasting in chronic kidney disease

  2018cites this paper
• How to Prevent Renal Cachexia? A Clinical Randomized Pilot Study Testing Oral Supplemental Nutrition in Hemodialysis Patients With and Without Human Immunodeficiency Virus Infection.

  2018cites this paper
• Muscle wasting in osteoarthritis model induced by anterior cruciate ligament transection

  2018cites this paper
• Obesity Paradox in Advanced Kidney Disease: From Bedside to the Bench.

  2018cites this paper
• Preferential recognition of advanced glycation end products by serum antibodies and low-grade systemic inflammation in diabetes mellitus and its complications.

  2018cites this paper
• Effect of Arabic Gum as Prebiotics and Lactobacillus casei Shirota (LcS) as Probiotic on Oxidative Stress and Renal Function in Adenine–Induced Chronic Renal Failure in Rats

  2018cites this paper
• Serum Leptin Concentration In Children With Chronic Renal Failure

  2018cites this paper
• Associations of pre‐existing co‐morbidities with skeletal muscle mass and radiodensity in patients with non‐metastatic colorectal cancer

  2018cites this paper
• Dietary sources of energy and nutrient intake among children and adolescents with chronic kidney disease

  2017cites this paper
• A study on relationship between elderly sarcopenia and inflammatory factors IL-6 and TNF-α

  2017cites this paper
• A comprehensive approach on metabolic dysfunction in chronic kidney disease

  2017influential citation
• Physical activity, immune function and inflammation in kidney patients (the PINK study): a feasibility trial protocol

  2017cites this paper
• Correlation between LDL, HDL, Total Cholesterol, and Triglyceride with the Degree of Chronic Kidney Disease in Children

  2017influential citation
• Early cardiovascular risk markers and cardiac function in children with chronic kidney disease

  2016cites this paper
• Suppression of muscle wasting by the plant‐derived compound ursolic acid in a model of chronic kidney disease

  2016cites this paper
• Oropharyngeal swallowing in chronic renal failure.

  2016cites this paper
• Modelos animales de calcificación vascular: vitamina E y magnesio como estrategias terapéuticas

  2016cites this paper
• CKD Stimulates Muscle Protein Loss Via Rho-associated Protein Kinase 1 Activation.

  2016cites this paper
• Analyses of melatonin, cytokines, and sleep in chronic renal failure

  2016cites this paper
• Fluvastatin combined with benazepril may contribute to the favorable prognosis of patients with atrial fibrillation.

  2016cites this paper
• Assessements of Protein Energy Wasting in Patients with Chronic Kidney Disease, Attending Renal Unit at Tikur Anbesa Specialized Hospital

  2016cites this paper
• Indoxyl sulfate potentiates skeletal muscle atrophy by inducing the oxidative stress-mediated expression of myostatin and atrogin-1

  2016cites this paper
• Metabolic alterations by indoxyl sulfate in skeletal muscle induce uremic sarcopenia in chronic kidney disease

  2016cites this paper
• Urinary Ghrelin Concentration in Children With Urinary Tract Infections Before and After Treatment

  2016cites this paper
• Fluvastatin Combined with Benazepril May Contribute to FavorablePrognosis of Auricular Fibrillation

  2016cites this paper
• Efecto de un programa de intervención nutricional sobre el estado nutricio de pacientes con enfermedad renal crónica estadios 3 y 4 del Hospital General de Teziutlán de la Secretaría de Salud

  2016cites this paper
• NF-κB expression and its association with nutritional status in hemodialysis patients

  2016cites this paper
• Glucocorticoid-Regulated Kinase: Linking Azotemia and Muscle Wasting in CKD.

  2016cites this paper
• Uremic myopathy: is oxidative stress implicated in muscle dysfunction in uremia?

  2015cites this paper
• Is there a connection between inflammation, telomerase activity and the transcriptional status of telomerase reverse transcriptase in renal failure?

  2015cites this paper
• Growth failure and nutrition considerations in chronic childhood wasting diseases.

  2015cites this paper
• The Impact of Exercising During Haemodialysis on Blood Pressure, Markers of Cardiac Injury and Systemic Inflammation - Preliminary Results of a Pilot Study

  2015cites this paper
• Cachexia & debility diagnoses in hospitalized children and adolescents with complex chronic conditions: evidence from the Kids’ Inpatient Database

  2015cites this paper
• The effect of sodium bicarbonate on cytokine secretion in CKD patients with metabolic acidosis.

  2015cites this paper
• Serum and Urine Leptin Concentrations in Children Before and After Treatment of Urinary Tract Infection.

  2015cites this paper
• Hypothalamic leptin gene therapy reduces body weight without accelerating age-related bone loss.

  2015cites this paper
• Efficacy of beta-hydroxy-beta-methylbutyrate (HMB) supplementation in hemodialysis patients

  2015cites this paper
• Haemoglobin levels in the chronic dialysis population in the Nephrology Unit at Chris Hani Baragwanath Academic Hospital

  2015cites this paper
• Exercise in haemodialysis patients: impact on markers of inflammation

  2015cites this paper
• Hypothalamic Leptin Gene Therapy Reduces Body Weight without Accelerating Age- 1

  2015cites this paper
• Efecto diferencial del calcitriol y del paricalcitol sobre el proceso de calcificación en células de músculo liso vascular.Mecanismos intracelulares implicados

  2015cites this paper