T cell exosomes induce cholesterol accumulation in human monocytes via phosphatidylserine receptor

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Journal of Cellular Physiology

• Publication date

  2007-07-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1002/jcp.21013PMID 17299798
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The Presumptive Phosphatidylserine Receptor Is Dispensable for Innate Anti-inflammatory Recognition and Clearance of Apoptotic Cells*

  2006cited by this paper
• Recognition ligands on apoptotic cells: a perspective

  2006cited by this paper
• Free cholesterol-loaded macrophages are an abundant source of tumor necrosis factor-alpha and interleukin-6: model of NF-kappaB- and map kinase-dependent inflammation in advanced atherosclerosis.

  2005cited by this paper
• Inflammation, atherosclerosis, and coronary artery disease.

  2005influential reference
• A comparative study of cytoplasmic granules imaged by the real-time microscope, Nile Red and Filipin in fibroblasts from patients with lipid storage diseases

  2005cited by this paper
• Role of cholesterol and lipid organization in disease

  2005cited by this paper
• Atherosclerosis: humoral and cellular factors of inflammation

  2005cited by this paper
• Isolation and culture of human macrophages.

  2005cited by this paper
• The phosphatidylserine receptor from Hydra is a nuclear protein with potential Fe(II) dependent oxygenase activity

  2004cited by this paper
• Nuclear localization of the phosphatidylserine receptor protein via multiple nuclear localization signals.

  2004cited by this paper
• Hide and seek: the secret identity of the phosphatidylserine receptor

  2004cited by this paper
• Endocytosis, intracellular sorting, and processing of exosomes by dendritic cells.

  2004cited by this paper
• Clearance of apoptotic cells: getting rid of the corpses.

  2004cited by this paper
• Inflammatory reactions in the pathogenesis of atherosclerosis.

  2003cited by this paper
• Fas (CD95) Induces Proinflammatory Cytokine Responses by Human Monocytes and Monocyte-Derived Macrophages12

  2003cited by this paper
• CD4+ T cells in atherosclerosis.

  2003cited by this paper
• The endoplasmic reticulum is the site of cholesterol-induced cytotoxicity in macrophages

  2003cited by this paper
• Regulation of membrane trafficking and subcellular organization of endocytic compartments revealed with FM1-43 in resting and activated human T cells.

  2003cited by this paper
• Caveolae/raft-dependent endocytosis

  2003cited by this paper
• The Biogenesis and Functions of Exosomes

  2002cited by this paper
• Consequences of cellular cholesterol accumulation: basic concepts and physiological implications.

  2002cited by this paper
• The macrophage foam cell as a target for therapeutic intervention

  2002cited by this paper
• TCR Activation of Human T Cells Induces the Production of Exosomes Bearing the TCR/CD3/ζ Complex1

  2002cited by this paper
• Release and Intercellular Transfer of Cell Surface CD81 Via Microparticles1

  2002cited by this paper
• Exosomes: composition, biogenesis and function

  2002cited by this paper
• Foam cell formation containing lipid droplets enriched with free cholesterol by hyperlipidemic serum.

  2001cited by this paper
• Phosphatidylserine (PS) induces PS receptor–mediated macropinocytosis and promotes clearance of apoptotic cells

  2001cited by this paper
• In vivo downregulation of T helper cell 1 immune responses reduces atherogenesis in apolipoprotein E-knockout mice.

  2001cited by this paper
• Phagocyte receptors for apoptotic cells: recognition, uptake, and consequences.

  2001cited by this paper
• Lymphocytes are important in early atherosclerosis.

  2001cited by this paper
• Differential Secretion of Fas Ligand- or APO2 Ligand/TNF-Related Apoptosis-Inducing Ligand-Carrying Microvesicles During Activation-Induced Death of Human T Cells1

  2001cited by this paper
• Transfer of CD4+ T Cells Aggravates Atherosclerosis in Immunodeficient Apolipoprotein E Knockout Mice

  2000cited by this paper
• Intracellular distribution and mobilization of unesterified cholesterol in adipocytes: triglyceride droplets are surrounded by cholesterol-rich ER-like surface layer structures.

  2000cited by this paper
• A receptor for phosphatidylserine-specific clearance of apoptotic cells

  2000influential reference
• Exosome: from internal vesicle of the multivesicular body to intercellular signaling device.

  2000cited by this paper
• Mechanisms of lipid-body formation.

  1999cited by this paper
• Activated Platelets Release Two Types of Membrane Vesicles: Microvesicles by Surface Shedding and Exosomes Derived From Exocytosis of Multivesicular Bodies and -Granules

  1999cited by this paper
• Exposure of phosphatidylserine is a general feature in the phagocytosis of apoptotic lymphocytes by macrophages

  1999cited by this paper
• Activated human T cells release bioactive Fas ligand and APO2 ligand in microvesicles.

  1999cited by this paper
• Activated platelets release two types of membrane vesicles: microvesicles by surface shedding and exosomes derived from exocytosis of multivesicular bodies and alpha-granules.

  1999cited by this paper
• Selective Enrichment of Tetraspan Proteins on the Internal Vesicles of Multivesicular Endosomes and on Exosomes Secreted by Human B-lymphocytes*

  1998cited by this paper
• Recognizing death: the phagocytosis of apoptotic cells.

  1998cited by this paper
• A Novel Technique For Mapping the Lipid Composition of Atherosclerotic Fatty Streaks by En Face Fluorescence Microscopy

  1997cited by this paper
• Endocytosis of GPI-anchored proteins in human lymphocytes: role of glycolipid-based domains, actin cytoskeleton, and protein kinases

  1996cited by this paper
• Selective retention of VLDL, IDL, and LDL in the arterial intima of genetically hyperlipidemic rabbits in vivo. Molecular size as a determinant of fractional loss from the intima-inner media.

  1995cited by this paper
• Production of tumor necrosis factor and interleukin-1 by macrophages from human atheromatous plaques.

  1993cited by this paper
• Nile red staining of lysosomal phospholipid inclusions

  1992cited by this paper
• The human leukemia cell line, THP-1: A multifacetted model for the study of monocyte-macrophage differentiation

  1991cited by this paper
• Use of Nile red stain in the detection of cholesteryl ester accumulation in acid lipase-deficient fibroblasts.

  1988cited by this paper
• Regional Accumulations of T Cells, Macrophages, and Smooth Muscle Cells in the Human Atherosclerotic Plaque

  1986cited by this paper
• Application of Nile red, a fluorescent hydrophobic probe, for the detection of neutral lipid deposits in tissue sections: comparison with oil red O.

  1985cited by this paper
• Nile red: a selective fluorescent stain for intracellular lipid droplets

  1985cited by this paper
• Histochemical detection and differentiation of free and esterified cholesterol in swine atherosclerosis using filipin.

  1984cited by this paper
• Effect of cell density on binding and uptake of low density lipoprotein by human fibroblasts

  1979cited by this paper

• Does extracellular vesicle specificity truly exist?

  2026cites this paper
• Revealing the Process of Vein Graft Failure: A Panoramic Review from Etiology Analysis to Mechanism Explanation and Treatment Strategy.

  2025cites this paper
• Extracellular Vesicles Derived from Breast Cancer Cells: Emerging Biomarkers of Tumor Progression and Metastasis

  2025cites this paper
• Lipopolysaccharide amplifies the endocytosis of circulating exosomes derived from aortic dissection patients by the endothelial cells via a JMJD6 dependent manner.

  2025cites this paper
• Young extracellular vesicles restore burn-induced adipose tissue immunometabolic and mitochondrial function in older mice

  2025cites this paper
• Exosomes and their roles in major depressive disorder: an overview of the research progress and perspectives

  2025cites this paper
• The Role of the Tumor Microenvironment (TME) in Advancing Cancer Therapies: Immune System Interactions, Tumor-Infiltrating Lymphocytes (TILs), and the Role of Exosomes and Inflammasomes

  2025cites this paper
• Roles of Mesenchymal Stem Cell-derived Extracellular Vesicles in Cancer: Development and Target Therapy

  2025cites this paper
• Unlocking the Potential of Extracellular Vesicles in Cardiovascular Disease

  2025cites this paper
• Exosomal non-coding RNAs as emerging drivers of immune dysregulation in melanoma

  2025influential citation
• Harnessing extracellular vesicles to tame inflammation: a new strategy for atherosclerosis therapy

  2025cites this paper
• Erkek Üreme Sisteminde Eksozomların Potansiyel Rolü

  2024cites this paper
• Review of exosomes and their potential for veterinary medicine.

  2024cites this paper
• Emerging role of sphingolipids and extracellular vesicles in development and therapeutics of cardiovascular diseases

  2024cites this paper
• Therapeutic potential of exosomes in spermatogenesis regulation and male infertility

  2024influential citation
• The Role of Adipose Tissue-derived Exosomes in Chronic Metabolic Disorders

  2024cites this paper
• Extracellular Vesicles as Mediators in Atherosclerotic Cardiovascular Disease

  2024cites this paper
• Effect of storage conditions on the quality of equine and canine mesenchymal stem cell derived nanoparticles including extracellular vesicles for research and therapy

  2024cites this paper
• A Review of the Use of Extracellular Vesicles in the Treatment of Neonatal Diseases: Current State and Problems with Translation to the Clinic

  2024cites this paper
• Extracellular vesicles originating from steatotic hepatocytes promote hepatic stellate cell senescence via AKT/mTOR signaling

  2024cites this paper
• RNA-encapsulating lipid nanoparticles in cancer immunotherapy: From pre-clinical studies to clinical trials.

  2024cites this paper
• Research progress on the mechanism of exosome-mediated virus infection

  2024influential citation
• The biological function of tumor-derived extracellular vesicles on metabolism

  2023cites this paper
• Emerging role of extracellular vesicles in multiple sclerosis: From cellular surrogates to pathogenic mediators and beyond.

  2023cites this paper
• The landscape of exosomal non-coding RNAs in breast cancer drug resistance, focusing on underlying molecular mechanisms

  2023cites this paper
• Exosomes as natural nanocarrier-based drug delivery system: recent insights and future perspectives

  2023cites this paper
• An update in the applications of exosomes in cancer theranostics: from research to clinical trials

  2023cites this paper
• Exosome regulation of immune response mechanism: Pros and cons in immunotherapy

  2023cites this paper
• T Cell Microvilli: Finger-Shaped External Structures Linked to the Fate of T Cells

  2023cites this paper
• Exosomal Non-Coding RNA Mediates Macrophage Polarization: Roles in Cardiovascular Diseases

  2023cites this paper
• Exosomal noncoding RNA-mediated spatiotemporal regulation of lipid metabolism: Implications in immune evasion and chronic inflammation.

  2023cites this paper
• The lipid composition of extracellular vesicles: applications in diagnostics and therapeutic delivery

  2023cites this paper
• Therapeutic application of mesenchymal stem cells derived exosomes in neurodegenerative diseases: A focus on non-coding RNAs cargo, drug delivery potential, perspective.

  2023cites this paper
• Roles of extracellular vesicles derived from immune cells in atherosclerosis

  2023cites this paper
• Increased extracellular vesicles (EVs) related to T cell-mediated inflammation and vascular function in familial hypercholesterolemia

  2023cites this paper
• Extracellular Vesicles from Immune Cells: A Biomedical Perspective

  2023cites this paper
• Liquid Biopsy at the Frontier of Kidney Diseases: Application of Exosomes in Diagnostics and Therapeutics

  2023cites this paper
• Exosomes in cardiovascular diseases: a blessing or a sin for the mankind

  2022cites this paper
• Engineered extracellular vesicles and their mimetics for cancer immunotherapy.

  2022cites this paper
• The role of phosphatidylserine on the membrane in immunity and blood coagulation

  2022cites this paper
• Non-small cell lung carcinoma (NSCLC): Implications on molecular pathology and advances in early diagnostics and therapeutics

  2022cites this paper
• The roles of small extracellular vesicles in cancer and immune regulation and translational potential in cancer therapy

  2022cites this paper
• Astronauts Plasma-Derived Exosomes Induced Aberrant EZH2-Mediated H3K27me3 Epigenetic Regulation of the Vitamin D Receptor

  2022cites this paper
• Inflammation driven metabolic regulation and adaptation in macrophages.

  2022cites this paper
• Plasma CD16+ Extracellular Vesicles Associate with Carotid Artery Intima-Media Thickness in HIV+ Adults on Combination Antiretroviral Therapy

  2022cites this paper
• Insight into Extracellular Vesicle-Cell Communication: From Cell Recognition to Intracellular Fate

  2022cites this paper
• Effect of Extracellular Vesicles From Multiple Cells on Vascular Smooth Muscle Cells in Atherosclerosis

  2022cites this paper
• Horizon of exosome-mediated bone tissue regeneration: The all-rounder role in biomaterial engineering

  2022cites this paper
• Exosomal long non-coding RNAs: novel molecules in gastrointestinal cancers’ progression and diagnosis

  2022cites this paper
• Message in a Bottle: Endothelial Cell Regulation by Extracellular Vesicles

  2022cites this paper
• Metabolites as extracellular vesicle cargo in health, cancer, pleural effusion, and cardiovascular diseases: An emerging field of study to diagnostic and therapeutic purposes.

  2022cites this paper
• High-Metastatic Melanoma Cells Promote the Metastatic Capability of Low-Metastatic Melanoma Cells via Exosomal Transfer of miR-411-5p

  2022cites this paper
• Exosome-mediated bioinspired drug delivery

  2021cites this paper
• Exosomes in Cardiovascular Diseases: Pathological Potential of Nano-Messenger

  2021cites this paper
• Small Extracellular Vesicles in Transplant Rejection

  2021cites this paper
• Circulating exosomes in cardiovascular disease: Novel carriers of biological information.

  2021cites this paper
• Extracellular vesicles in anti-tumor immunity.

  2021cites this paper
• What we know on the potential use of exosomes for nanodelivery.

  2021cites this paper
• Role and Function of T Cell-Derived Exosomes and Their Therapeutic Value

  2021cites this paper
• Role of extracellular vesicles in atherosclerosis: An update

  2021cites this paper
• Exosomes and Atherogenesis

  2021cites this paper
• Emerging biosensing platforms for quantitative detection of exosomes as diagnostic biomarkers

  2021cites this paper
• Emerging Role of Extracellular Vesicles in Biomarking the Gastrointestinal Diseases

  2021cites this paper
• Peptide ligand-SiO2 microspheres with specific affinity for phosphatidylserine as a new strategy to isolate exosomes and application in proteomics to differentiate hepatic cancer

  2021cites this paper
• Socially Distanced Intercellular Communication: Mechanisms for Extracellular Vesicle Cargo Delivery.

  2021cites this paper
• Application of mesenchymal stem cell-derived exosomes in kidney diseases.

  2021cites this paper
• The pathological growth of the prostate gland in atherogenic contexts.

  2021cites this paper
• The role of lipids in exosome biology and intercellular communication: Function, analytics and applications

  2021cites this paper
• Extracellular vesicles in atherothrombosis and cardiovascular disease: Friends and foes.

  2021cites this paper
• [Extracellular vesicles and cardiovascular diseases].

  2021cites this paper
• Role of adipose tissue in regulating fetal growth in gestational diabetes mellitus.

  2020cites this paper
• Cardiovascular Exosomes and MicroRNAs in Cardiovascular Physiology and Pathophysiology

  2020cites this paper
• Characterization and Fine Structure of Exosomes

  2020cites this paper
• Exosome-based immunotherapy: a promising approach for cancer treatment

  2020cites this paper
• Exosomes in Cardiovascular Diseases

  2020cites this paper
• Progress in exosome associated tumor markers and their detection methods

  2020cites this paper
• Role of membrane lipids in colon differentiation unravelled by mass spectrometry imaging: arachidonic acid beyond inflammation

  2020cites this paper
• Non-coding RNAs and Exosomes: Their Role in the Pathogenesis of Sepsis

  2020cites this paper
• A regulatory role of scavenger receptor class B type 1 in endocytosis and lipid droplet formation induced by liposomes containing phosphatidylethanolamine in HEK293T cells.

  2020cites this paper
• Exosomes in metabolic syndrome

  2020cites this paper
• Lipidomic characterization of exosomes isolated from human plasma using various mass spectrometry techniques.

  2020cites this paper
• The Heat Shock Protein 27 Immune Complex Enhances Exosomal Cholesterol Efflux

  2020cites this paper
• Exosomes are the Driving Force in Preparing the Soil for the Metastatic Seeds: Lessons from the Prostate Cancer

  2020cites this paper
• Exosomes: Multifaceted Messengers in Atherosclerosis

  2020cites this paper
• Extracellular vesicles in virus infection and pathogenesis.

  2020cites this paper
• Extracellular vesicle signalling in atherosclerosis

  2020cites this paper
• Current Knowledge and Future Perspectives on Mesenchymal Stem Cell-Derived Exosomes as a New Therapeutic Agent

  2020cites this paper
• The role of exosome lipids in central nervous system diseases

  2020cites this paper
• Exosome-mediated metabolic reprogramming: the emerging role in tumor microenvironment remodeling and its influence on cancer progression

  2020cites this paper
• Circulating microvesicles as mediators of acute pulmonary vascular inflammation

  2020cites this paper
• The crosstalk: exosomes and lipid metabolism

  2020cites this paper
• Exosomes from nicotine-stimulated macrophages accelerate atherosclerosis through miR-21-3p/PTEN-mediated VSMC migration and proliferation

  2019cites this paper
• Extracellular Vesicles as Messengers in Atherosclerosis

  2019cites this paper
• Emerging role of extracellular vesicles in the regulation of skeletal muscle adaptation.

  2019cites this paper
• Exosome: An Emerging Source of Biomarkers for Human Diseases.

  2019cites this paper
• Schistosoma mansoni-Derived Lipids in Extracellular Vesicles: Potential Agonists for Eosinophillic Tissue Repair

  2019cites this paper
• Cellular-Defined Microenvironmental Internalization of Exosomes

  2019cites this paper
• Engineering of Surface Proteins in Extracellular Vesicles for Tissue-Specific Targeting

  2019cites this paper
• Extracellular vesicles in atherosclerosis.

  2019cites this paper
• Exosomes: Versatile Nano Mediators of Immune Regulation

  2019cites this paper