PKR Stimulates NF-κB Irrespective of Its Kinase Function by Interacting with the IκB Kinase Complex

No abstract is available for this paper.

• Publication year

  2000

• Venue

  Molecular and Cellular Biology

• Publication date

  2000-07-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1128/MCB.20.13.4532-4542.2000PMID 10848580PMCID PMC85837
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Antiviral Actions of Interferons

  2001cited by this paper
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  1999cited by this paper
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  1999cited by this paper
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  1999cited by this paper
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  1999cited by this paper
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  1999cited by this paper
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  1999cited by this paper
• Severe Liver Degeneration in Mice Lacking the IκB Kinase 2 Gene

  1999cited by this paper
• Mutant Cells That Do Not Respond to Interleukin-1 (IL-1) Reveal a Novel Role for IL-1 Receptor-Associated Kinase

  1999cited by this paper
• Apoptosis: an innate immune response to virus infection.

  1999cited by this paper
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  1999cited by this paper
• Complementation Cloning of NEMO, a Component of the IκB Kinase Complex Essential for NF-κB Activation

  1998influential reference
• RNase L Mediates the Antiviral Effect of Interferon through a Selective Reduction in Viral RNA during Encephalomyocarditis Virus Infection

  1998cited by this paper
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  1998cited by this paper
• RIP2 is a novel NF-kappaB-activating and cell death-inducing kinase.

  1998cited by this paper
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  1998cited by this paper
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  1998cited by this paper
• 2',5'-Oligoadenylate-antisense chimeras cause RNase L to selectively degrade bcr/abl mRNA in chronic myelogenous leukemia cells.

  1998cited by this paper
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  1998cited by this paper
• Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation.

  1998cited by this paper
• RIP2 Is a Novel NF-κB-activating and Cell Death-inducing Kinase*

  1998cited by this paper
• Activation of the IkappaB alpha kinase complex by MEKK1, a kinase of the JNK pathway.

  1997cited by this paper
• NF-kappaB activation: the I kappaB kinase revealed?

  1997cited by this paper
• Cloning and characterization of a cDNA encoding a protein synthesis initiation factor-2alpha (eIF-2alpha) kinase from Drosophila melanogaster. Homology To yeast GCN2 protein kinase.

  1997cited by this paper
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  1997cited by this paper
• The IκB Kinase Complex (IKK) Contains Two Kinase Subunits, IKKα and IKKβ, Necessary for IκB Phosphorylation and NF-κB Activation

  1997cited by this paper
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  1997cited by this paper
• Characterization of a mutant cell line that does not activate NF-kappaB in response to multiple stimuli

  1997cited by this paper
• Inhibition of NF‐κB cellular function via specific targeting of the IκB‐ubiquitin ligase

  1997cited by this paper
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  1997cited by this paper
• IKK-1 and IKK-2: Cytokine-Activated IκB Kinases Essential for NF-κB Activation

  1997cited by this paper
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  1997cited by this paper
• Cloning and Characterization of a cDNA Encoding a Protein Synthesis Initiation Factor-2α (eIF-2α) Kinase fromDrosophila melanogaster

  1997cited by this paper
• MAP3K-related kinase involved in NF-KB induction by TNF, CD95 and IL-1

  1997cited by this paper
• The IkB Kinase Complex (IKK) Contains Two Kinase Subunits, IKKa and IKKb, Necessary for IkB Phosphorylation and NF-kB Activation

  1997cited by this paper
• A cytokine-responsive IκB kinase that activates the transcription factor NF-κB

  1997cited by this paper
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  1997cited by this paper
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  1997cited by this paper
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  1997cited by this paper
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  1997cited by this paper
• Deficient cytokine signaling in mouse embryo fibroblasts with a targeted deletion in the PKR gene: role of IRF‐1 and NF‐κB

  1997cited by this paper
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  1997cited by this paper
• Induction of CD4 expression and human immunodeficiency virus type 1 replication by mutants of the interferon-inducible protein kinase PKR

  1997cited by this paper
• The Double-Stranded RNA-Dependent Protein Kinase PKR: Structure and Function

  1997cited by this paper
• The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation.

  1997cited by this paper
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  1996cited by this paper
• The NF-kappa B and I kappa B proteins: new discoveries and insights.

  1996cited by this paper
• The Kinase Insert Domain of Interferon-induced Protein Kinase PKR Is Required for Activity but Not for Interaction with the Pseudosubstrate K3L*

  1996cited by this paper
• Specific Mutations Near the Amino Terminus of Double-stranded RNA-dependent Protein Kinase (PKR) Differentially Affect Its Double-stranded RNA Binding and Dimerization Properties*

  1996cited by this paper
• RIP mediates tumor necrosis factor receptor 1 activation of NF‐kappaB but not Fas/APO‐1‐initiated apoptosis.

  1996cited by this paper
• NF-κB: Ten Years After

  1996cited by this paper
• THE NF-κB AND IκB PROTEINS: New Discoveries and Insights

  1996cited by this paper
• Human PKR transfected into murine cells stimulates expression of genes under control of the HIV1 or HTLV-I LTR.

  1995cited by this paper
• Stimulation-dependent I kappa B alpha phosphorylation marks the NF-kappa B inhibitor for degradation via the ubiquitin-proteasome pathway.

  1995cited by this paper
• The role of the dsRNA-activated kinase, PKR, in signal transduction

  1995cited by this paper
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  1995influential reference
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  1995cited by this paper
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  1995cited by this paper
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  1994cited by this paper
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  1994cited by this paper
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  1994cited by this paper
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  1993cited by this paper
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  1993cited by this paper
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  1993cited by this paper
• Intramolecular masking of the nuclear location signal and dimerization domain in the precursor for the p50 NF-κB subunit

  1992cited by this paper
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• Human p68 kinase exhibits growth suppression in yeast and homology to the translational regulator GCN2.

  1992cited by this paper
• Intramolecular masking of the nuclear location signal and dimerization domain in the precursor for the p50 NF-kappa B subunit.

  1992cited by this paper
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  1991cited by this paper
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  1991cited by this paper
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  1991cited by this paper
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  1991cited by this paper
• Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon

  1990cited by this paper
• The Double Stranded RNA-Activated Protein Kinase Induced by Interferon: dsRNA-PK

  1989cited by this paper
• Tumor necrosis factor alpha activates human immunodeficiency virus type 1 through induction of nuclear factor binding to the NF-kappa B sites in the long terminal repeat.

  1989cited by this paper
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  1988cited by this paper
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  1985cited by this paper
• Tax Induces Nuclear Translocation of NF-KB through Dissociation

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• Identification and Characterization of Pancreatic Eukaryotic Initiation Factor 2 a -Subunit Kinase, PEK, Involved in Translational Control

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