Protein hydroxylation: prolyl 4‐hydroxylase, an enzyme with four cosubstrates and a multifunctional subunit

No abstract is available for this paper.

• Publication year

  1989

• Venue

  The FASEB Journal

• Publication date

  1989-03-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1096/fasebj.3.5.2537773PMID 2537773
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Evidence that luminal ER proteins are sorted from secreted proteins in a post‐ER compartment.

  1988cited by this paper
• Assignment of the gene coding for both the beta-subunit of prolyl 4-hydroxylase and the enzyme disulfide isomerase to human chromosome region 17p11----qter.

  1988cited by this paper
• Protein disulphide-isomerase: a homologue of thioredoxin implicated in the biosynthesis of secretory proteins.

  1988cited by this paper
• Syncatalytic inactivation of prolyl 4-hydroxylase by anthracyclines.

  1988cited by this paper
• Decreased extracellular matrix production in scurvy involves a humoral factor other than ascorbate.

  1988cited by this paper
• Polyclonal and monoclonal antibodies to human lysyl hydroxylase and studies on the molecular heterogeneity of the enzyme.

  1988cited by this paper
• Prolyl 4-hydroxylase from Volvox carteri. A low-Mr enzyme antigenically related to the alpha subunit of the vertebrate enzyme.

  1988cited by this paper
• Molecular cloning of a multifunctional chicken protein acting as the prolyl 4-hydroxylase beta-subunit, protein disulphide-isomerase and a cellular thyroid-hormone-binding protein. Comparison of cDNA-deduced amino acid sequences with those in other species.

  1988cited by this paper
• Identification of [hydroxyproline3]-lysyl-bradykinin released from human plasma protein by kallikrein.

  1988cited by this paper
• The role of hydroxyproline in collagen folding: Conformational energy calculations on oligopeptides containing proline and hydroxyproline

  1988cited by this paper
• Processive action of the two peptide binding sites of prolyl 4-hydroxylase in the hydroxylation of procollagen.

  1988influential reference
• The effectiveness of inhibitors of soluble prolyl hydroxylase against the enzyme in the cisternae of isolated bone microsomes.

  1988cited by this paper
• Glycosylation site binding protein, a component of oligosaccharyl transferase, is highly similar to three other 57 kd luminal proteins of the ER.

  1988cited by this paper
• Two distinct classes of carbohydrate-recognition domains in animal lectins.

  1988cited by this paper
• Localisation and quantification of the 2-oxoglutarate binding sites of prolyl 4-hydroxylase by photoaffinity labelling with tritiated 5-azidopyridine-2-carboxylic acid

  1988cited by this paper
• Molecular cloning and complete amino-acid sequence of form-I phosphoinositide-specific phospholipase C

  1988cited by this paper
• Syncatalytic inactivation of prolyl 4-hydroxylase by synthetic peptides containing the unphysiologic amino acid 5-oxaproline.

  1988cited by this paper
• Characterization of the human gene for a polypeptide that acts both as the beta subunit of prolyl 4-hydroxylase and as protein disulfide isomerase.

  1988cited by this paper
• Chromosomal localization of the gene for a human thyroid hormone-binding protein.

  1988cited by this paper
• Molecular cloning of the beta‐subunit of human prolyl 4‐hydroxylase. This subunit and protein disulphide isomerase are products of the same gene.

  1987cited by this paper
• A single polypeptide acts both as the beta subunit of prolyl 4-hydroxylase and as a protein disulfide-isomerase.

  1987cited by this paper
• Time-dependent inactivation of chick-embryo prolyl 4-hydroxylase by coumalic acid. Evidence for a syncatalytic mechanism.

  1987cited by this paper
• Photoaffinity labelling of the 2-oxoglutarate binding site of prolyl 4-hydroxylase with 5-azidopyridine-2-carboxylic acid.

  1987cited by this paper
• The nucleotide sequence of a human cellular thyroid hormone binding protein present in endoplasmic reticulum.

  1987cited by this paper
• Sequence of membrane-associated thyroid hormone binding protein from bovine liver: its identity with protein disulphide isomerase.

  1987cited by this paper
• Reduction of collagen production in keloid fibroblast cultures by ethyl-3,4-dihydroxybenzoate. Inhibition of prolyl hydroxylase activity as a mechanism of action.

  1987cited by this paper
• Partial identity of the 2-oxoglutarate and ascorbate binding sites of prolyl 4-hydroxylase.

  1986cited by this paper
• Sequence of protein disulphide isomerase and implications of its relationship to thioredoxin

  1985influential reference
• Biosynthesis of prolyl hydroxylase: evidence for two separate dolichol-media pathways of glycosylation.

  1985cited by this paper
• Thioredoxin.

  1985cited by this paper
• Post‐Translational Processing of Procollagens

  1985cited by this paper
• Photoaffinity labeling of peptide binding sites of prolyl 4-hydroxylase with N-(4-azido-2-nitrophenyl)glycyl-(Pro-Pro-Gly)5.

  1985cited by this paper
• Characterization of the oligosaccharides of prolyl hydroxylase, a microsomal glycoprotein.

  1985influential reference
• The 2-oxoglutarate binding site of prolyl 4-hydroxylase. Identification of distinct subsites and evidence for 2-oxoglutarate decarboxylation in a ligand reaction at the enzyme-bound ferrous ion.

  1984cited by this paper
• Pharmacological inhibition of excessive collagen deposition in fibrotic diseases.

  1984cited by this paper
• Stoicheiometry and kinetics of the prolyl 4-hydroxylase partial reaction.

  1984cited by this paper
• Ascorbate is consumed stoichiometrically in the uncoupled reactions catalyzed by prolyl 4-hydroxylase and lysyl hydroxylase.

  1984cited by this paper
• A stereochemical concept for the catalytic mechanism of prolylhydroxylase: applicability to classification and design of inhibitors.

  1982influential reference
• The biosynthesis of collagen and its disorders (second of two parts).

  1979cited by this paper
• The biosynthesis of collagen and its disorders (first of two parts).

  1979cited by this paper
• [Biosynthesis of collagen and its disorders].

  1979cited by this paper
• Intracellular Steps in the Biosynthesis of Collagen

  1976cited by this paper
• Prolyl hydroxylase.

  1974cited by this paper

• Appraisal of prolyl 4-hydroxylase alpha subunit gene polymorphisms in Spondyloepimetaphyseal dysplasia of Handigodu type (SEMDHG)

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  2018cites this paper
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  2018cites this paper
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  2017cites this paper
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  2015cites this paper
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  2015cites this paper
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  2015cites this paper
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