Metabolic engineering of Saccharomyces cerevisiae for production of fatty acid-derived biofuels and chemicals.

No abstract is available for this paper.

• Publication year

  2014

• Venue

  Metabolic Engineering

• Publication date

  Unknown publication date

• Fields of study

  Biology, Chemistry, Engineering, Environmental Science, Medicine

• Identifiers
  DOI 10.1016/j.ymben.2013.07.003PMID 23899824
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Engineering the push and pull of lipid biosynthesis in oleaginous yeast Yarrowia lipolytica for biofuel production.

  2013influential reference
• Modular optimization of multi-gene pathways for fatty acids production in E. coli

  2013cited by this paper
• Metabolic engineering for enhanced fatty acids synthesis in Saccharomyces cerevisiae.

  2013influential reference
• Synthesis of customized petroleum-replica fuel molecules by targeted modification of free fatty acid pools in Escherichia coli

  2013cited by this paper
• Production of amorphadiene in yeast, and its conversion to dihydroartemisinic acid, precursor to the antimalarial agent artemisinin

  2012cited by this paper
• Functional expression and characterization of five wax ester synthases in Saccharomyces cerevisiae and their utility for biodiesel production

  2012influential reference
• Synthesis of FAEEs from glycerol in engineered Saccharomyces cerevisiae using endogenously produced ethanol by heterologous expression of an unspecific bacterial acyltransferase

  2012influential reference
• Engineered reversal of the β-oxidation cycle for the synthesis of fuels and chemicals

  2011cited by this paper
• Delete and repeat: a comprehensive toolkit for sequential gene knockout in the budding yeast Saccharomyces cerevisiae.

  2011cited by this paper
• Microbial production of fatty-acid-derived fuels and chemicals from plant biomass

  2010influential reference
• Quantitative analysis and engineering of fatty acid biosynthesis in E. coli.

  2010cited by this paper
• Functional expression of five Arabidopsis fatty acyl-CoA reductase genes in Escherichia coli.

  2009cited by this paper
• Yarrowia lipolytica as a model for bio-oil production.

  2009cited by this paper
• Biofuel alternatives to ethanol: pumping the microbial well.

  2008cited by this paper
• Overproduction of free fatty acids in E. coli: implications for biodiesel production.

  2008cited by this paper
• DGA1 (diacylglycerol acyltransferase gene) overexpression and leucine biosynthesis significantly increase lipid accumulation in the Deltasnf2 disruptant of Saccharomyces cerevisiae.

  2007cited by this paper
• Frozen competent yeast cells that can be transformed with high efficiency using the LiAc/SS carrier DNA/PEG method

  2007cited by this paper
• Malic enzyme: the controlling activity for lipid production? Overexpression of malic enzyme in Mucor circinelloides leads to a 2.5-fold increase in lipid accumulation.

  2007cited by this paper
• High-efficiency yeast transformation using the LiAc/SS carrier DNA/PEG method

  2007cited by this paper
• Fatty acid synthesis and elongation in yeast.

  2007influential reference
• Identification of Genes Affecting Lipid Content Using Transposon Mutagenesis in Saccharomyces cerevisiae

  2006cited by this paper
• Engineering of Promoter Replacement Cassettes for Fine-Tuning of Gene Expression in Saccharomyces cerevisiae

  2006influential reference
• Environmental, economic, and energetic costs and benefits of biodiesel and ethanol biofuels.

  2006cited by this paper
• Influence of glucose concentration on the physiology and lipid composition of some yeasts

  2006influential reference
• Consolidated bioprocessing of cellulosic biomass: an update.

  2005cited by this paper
• The Wax Ester Synthase/Acyl Coenzyme A:Diacylglycerol Acyltransferase from Acinetobacter sp. Strain ADP1: Characterization of a Novel Type of Acyltransferase

  2005cited by this paper
• I. IDENTIFICATION OF TWO FATTY ACYL-COENZYME A REDUCTASES WITH DIFFERENT SUBSTRATE SPECIFICITIES AND TISSUE DISTRIBUTIONS*

  2004cited by this paper
• Bacteriophage contamination: is there a simple method to reduce its deleterious effects in laboratory cultures and biotechnological factories?

  2004cited by this paper
• Mammalian Wax Biosynthesis

  2004cited by this paper
• Microbial Type I Fatty Acid Synthases (FAS): Major Players in a Network of Cellular FAS Systems

  2004influential reference
• Synthesis of Novel Lipids in Saccharomyces cerevisiae by Heterologous Expression of an Unspecific Bacterial Acyltransferase

  2004cited by this paper
• Manipulation of malic enzyme in Saccharomyces cerevisiae for increasing NADPH production capacity aerobically in different cellular compartments.

  2004cited by this paper
• A second set of loxP marker cassettes for Cre-mediated multiple gene knockouts in budding yeast.

  2002influential reference
• Seed-specific over-expression of an Arabidopsis cDNA encoding a diacylglycerol acyltransferase enhances seed oil content and seed weight.

  2001cited by this paper
• The genetics of fatty acid metabolism in Saccharomyces cerevisiae.

  2001influential reference
• Phospholipid:diacylglycerol acyltransferase: an enzyme that catalyzes the acyl-CoA-independent formation of triacylglycerol in yeast and plants.

  2000cited by this paper
• Expression in yeast and tobacco of plant cDNAs encoding acyl CoA:diacylglycerol acyltransferase.

  2000cited by this paper
• Overproduction of Acetyl-CoA Carboxylase Activity Increases the Rate of Fatty Acid Biosynthesis in Escherichia coli *

  2000influential reference
• Purification of a jojoba embryo fatty acyl-coenzyme A reductase and expression of its cDNA in high erucic acid rapeseed.

  2000cited by this paper
• Cloning of a cDNA encoding diacylglycerol acyltransferase from Arabidopsis thaliana and its functional expression

  1999cited by this paper
• The role of malic enzyme in the regulation of lipid accumulation in filamentous fungi.

  1999cited by this paper
• Role of acylCoA binding protein in acylCoA transport, metabolism and cell signaling

  1999cited by this paper
• Resolution and purification of an aldehyde-generating and an alcohol-generating fatty acyl-CoA reductase from pea leaves (Pisum sativum L.).

  1997cited by this paper
• A Saccharomyces cerevisiae homolog of the human adrenoleukodystrophy transporter is a heterodimer of two half ATP-binding cassette transporters.

  1996influential reference
• Regulation of fatty acid biosynthesis in Escherichia coli.

  1993cited by this paper
• Peroxisomal multifunctional beta-oxidation protein of Saccharomyces cerevisiae. Molecular analysis of the fox2 gene and gene product.

  1992cited by this paper
• Cloning of the yeast FAS3 gene and primary structure of yeast acetyl-CoA carboxylase.

  1992cited by this paper
• Vectors for expression of cloned genes in yeast: regulation, overproduction, and underproduction.

  1991cited by this paper
• Regulation of transcription of the gene coding for peroxisomal 3-oxoacyl-CoA thiolase of Saccharomyces cerevisiae.

  1991cited by this paper
• Structure and transcriptional control of the Saccharomyces cerevisiae POX1 gene encoding acyl-coenzyme A oxidase.

  1990cited by this paper
• A positive selection for mutants lacking orotidine-5′-phosphate decarboxylase activity in yeast: 5-fluoro-orotic acid resistance

  1984influential reference
• Inhibition of Rat-Liver Acetyl-Coenzyme-A Carboxylase by Palmitoyl-Coenzyme A

  1978cited by this paper
• Inhibition of rat-liver acetyl-coenzyme-A carboxylase by palmitoyl-coenzyme A. Formation of equimolar enzyme-inhibitor complex.

  1978cited by this paper

• Deletion of the Fatty Acid Synthase Gene Enhanced Lipid Accumulation in the Oleaginous Fungus Mucor circinelloides WJ11.

  2026cites this paper
• Yeast Engineering for Antioxidant Production

  2026cites this paper
• Recent advances in microbial production of odd-chain fatty acids

  2026cites this paper
• Yeast-Derived Esters in Wine: Biosynthesis, Regulation, and Metabolic Engineering.

  2026cites this paper
• Microbial lipids for a sustainable future: the growing potential of synthetic microbial engineering for consumer oils.

  2026cites this paper
• Artemisia annua and traditional medicine in Madagascar: Its history and challenges

  2025cites this paper
• Combinatorial metabolic engineering of alkane biosynthesis in the osmotolerant yeast Debaryomyces hansenii CBS 767

  2025cites this paper
• Synthetic biology strategies for sustainable bioplastic production by yeasts.

  2025cites this paper
• Biotransformation of Microalgal Biomass by Lactic Acid Bacteria and Saccharomyces cerevisiae: Implications for Food and Sustainability

  2025cites this paper
• Advancements in Metabolic Engineering: Enhancing Biofuel Production Through Escherichia coli and Saccharomyces cerevisiae Models

  2025cites this paper
• Parameterization of cell-free systems with time-series data using KETCHUP

  2025cites this paper
• Mechanism investigation into static magnetic field effects on enhancing surfactin productivity by Bacillus subtilis

  2025cites this paper
• Fatty acid synthase in high and low lipid-producing strains of Mucor circinelloides: identification, phylogenetic analysis, and expression profiling during growth and lipid accumulation

  2025cites this paper
• Fatty acid synthesis: A critical factor determining mycelial growth rate in Pleurotus tuoliensis

  2025cites this paper
• Metabolic engineering and synthetic biology for the environment: from perspectives of biodetection, bioremediation, and biomanufacturing

  2025cites this paper
• Recent trends in microbial production of alkanes

  2025cites this paper
• Engineering yeast for tailored fatty acid profiles

  2025cites this paper
• Advanced Fungal Biotechnologies in Accomplishing Sustainable Development Goals (SDGs): What Do We Know and What Comes Next?

  2024cites this paper
• Pathway elucidation and heterologous reconstitution of the long‐chain alkane pentadecane biosynthesis from Pogostemon cablin

  2024cites this paper
• Metabolic Engineering for Squalene Production: Advances and Perspectives.

  2024cites this paper
• Crucial amino acids identified in Δ12 fatty acid desaturases related to linoleic acid production in Perilla frutescens

  2024cites this paper
• High-throughput relative quantification of fatty acids by 12-plex isobaric labeling and microchip capillary electrophoresis - Mass spectrometry.

  2024cites this paper
• Microbial metabolic engineering techniques in the application of fatty acid production

  2024cites this paper
• Biotechnological advances in the production of unusual fatty acids in transgenic plants and recombinant microorganisms.

  2024cites this paper
• Combined effects of nitrogen limitation and overexpression of malic enzyme gene on lipid accumulation in Dunaliella parva.

  2024cites this paper
• Recent trends in metabolic engineering for microbial production of value-added natural products

  2024cites this paper
• Microbial Squalene: A Sustainable Alternative for the Cosmetics and Pharmaceutical Industry – A Review

  2024cites this paper
• Engineering high production of fatty alcohols from methanol by constructing coordinated dual biosynthetic pathways.

  2024cites this paper
• Advanced metabolic Engineering strategies for the sustainable production of free fatty acids and their derivatives using yeast

  2024cites this paper
• Strategies for improving fengycin production: a review

  2024cites this paper
• Transcriptomics and proteomics analyses reveal the molecular mechanisms of yeast cells regulated by Phe-Cys against ethanol-oxidation cross-stress.

  2024cites this paper
• Exploring engineering strategies that enhance de novo production of exotic cyclopropane fatty acids in Saccharomyces cerevisiae

  2024cites this paper
• Fermentation of organic wastes through oleaginous microorganisms for lipid production - Challenges and opportunities

  2024cites this paper
• Microbial Cell Factories: Biodiversity, Pathway Construction, Robustness, and Industrial Applicability

  2024cites this paper
• Genomic analysis and overexpressing the acetyl-CoA carboxylase of oleaginous Saccharomyces cerevisiae CU-TPD4 for enhanced lipid production from agricultural residues

  2024cites this paper
• Assessment of lipid synthesis from sugarcane biomass by adaptive strains of Rhodosporidium toruloides

  2024cites this paper
• Strategies for cultivation, enhancing lipid production, and recovery in oleaginous yeasts.

  2024cites this paper
• Saccharomyces cerevisiae cellular engineering for the production of FAME biodiesel

  2024cites this paper
• Utilization of diverse probiotics to create human health promoting fatty acids: A review.

  2024cites this paper
• Integration of engineering microbial consortium and boosting extracellular amylase of B. amyloliquefaciens for intensifying bioconversion of food waste into lipopeptides

  2024cites this paper
• The powerful function of Saccharomyces cerevisiae in food science and other fields: A critical review

  2024cites this paper
• Research advancements in the maintenance mechanism of Sporidiobolus pararoseus enhancing the quality of soy sauce during fermentation.

  2024cites this paper
• Improved engineered fungal-bacterial commensal consortia simultaneously degrade multiantibiotics and biotransform food waste into lipopeptides.

  2024cites this paper
• A comprehensive review on microbial lipid production from wastes: research updates and tendencies

  2023cites this paper
• Engineering Rhodosporidium toruloides for production of 3-Hydroxypropionic acid from lignocellulosic Hydrolysate.

  2023cites this paper
• Optimization of a hybrid bacterial/Arabidopsis thaliana fatty acid synthase system II in Saccharomyces cerevisiae

  2023cites this paper
• Strategies to Enhance the Biosynthesis of Monounsaturated Fatty Acids in Escherichia coli

  2023cites this paper
• Focus and Insights into the Synthetic Biology-Mediated Chassis of Economically Important Fungi for the Production of High-Value Metabolites

  2023cites this paper
• Mass Spectrometry-Based High-Throughput Quantification of Bioproducts in Liquid Culture.

  2023cites this paper
• Biosynthesis pathways of expanding carbon chains for producing advanced biofuels

  2023cites this paper
• Biocatalytic Production of Odor-Active Fatty Aldehydes from Fungal Lipids.

  2023cites this paper
• Molecular insights into mutation-induced conformational changes in Acetyl CoA Carboxylase for improved activity.

  2023cites this paper
• Tuning Fatty Acid Profile and Yield in Pichia pastoris

  2023influential citation
• Adaptive Evolution and Metabolic Engineering Boost Lycopene Production in Saccharomyces cerevisiae via Enhanced Precursors Supply and Utilization.

  2023cites this paper
• Metabolic engineering of Corynebacterium glutamicum for fatty alcohol production from glucose and wheat straw hydrolysate

  2023cites this paper
• Data-Driven Modeling and Analysis of Fatty Acid Desaturase in Plants

  2023cites this paper
• Engineering acetyl-CoA metabolism to enhance stress tolerance of yeast by regulating membrane functionality.

  2023cites this paper
• Optimizing Ethanol Production in Saccharomyces cerevisiae at Ambient and Elevated Temperatures through Machine Learning-Guided Combinatorial Promoter Modifications

  2023cites this paper
• Diacids from Oil Producing Plant

  2022cites this paper
• Expression of Yarrowia lipolytica acetyl-CoA carboxylase in Saccharomyces cerevisiae and its effect on in-vivo accumulation of Malonyl-CoA

  2022cites this paper
• Design and application of a kinetic model of lipid metabolism in Saccharomyces cerevisiae.

  2022cites this paper
• Synthetic metabolism without the TCA cycle

  2022cites this paper
• Mutualistic microbial community of Bacillus amyloliquefaciens and recombinant Yarrowia lipolytica co-produced lipopeptides and fatty acids from food waste.

  2022cites this paper
• Tailored designing of a diploid S. cerevisiae natural isolate for increased production of fatty acid ethyl ester

  2022cites this paper
• Metabolic reconfiguration enables synthetic reductive metabolism in yeast

  2022cites this paper
• Catalytic synthesis of isoprenol from fatty acid ester over bimetallic Cu–Fe catalysts

  2022cites this paper
• An Overview of Enzymes and Rate-Limiting Steps Responsible for Lipid Production in Oleaginous Yeast

  2022influential citation
• Acyl-CoA:diacylglycerol acyltransferase: Properties, physiological roles, metabolic engineering and intentional control.

  2022cites this paper
• Biosynthesis of alkanes/alkenes from fatty acids or derivatives (triacylglycerols or fatty aldehydes).

  2022cites this paper
• The cell wall and the response and tolerance to stresses of biotechnological relevance in yeasts

  2022cites this paper
• Fatty acid feedstocks enable a highly efficient glyoxylate‐TCA cycle for high‐yield production of β‐alanine

  2022cites this paper
• Washington University Open Washington University Open Engineering Biosensors for Short-chain Alcohols Engineering Biosensors for Short-chain Alcohols

  2022cites this paper
• Unusual aldehyde reductase activity for the production of full-length fatty alcohol by cyanobacterial aldehyde deformylating oxygenase.

  2022cites this paper
• Engineering Saccharomyces cerevisiae for production of the capsaicinoid nonivamide

  2022cites this paper
• Genetic engineering of the branched‐chain fatty acid biosynthesis pathway to enhance surfactin production from Bacillus subtilis

  2022cites this paper
• Exploitation of Hetero- and Phototrophic Metabolic Modules for Redox-Intensive Whole-Cell Biocatalysis

  2022cites this paper
• Metabolic Engineering Strategies for Improved Lipid Production and Cellular Physiological Responses in Yeast Saccharomyces cerevisiae

  2022influential citation
• Comparative transcriptomic and lipidomic analysis of oleic environment adaptation in Saccharomyces cerevisiae: insight into metabolic reprogramming and lipid membrane expansion

  2022cites this paper
• Role of Cytosolic Malic Enzyme in Oleaginicity of High-Lipid-Producing Fungal Strain Mucor circinelloides WJ11

  2022cites this paper
• Recent Advances in Biofuel Production through Metabolic Engineering.

  2022cites this paper
• A paradigm shift towards production of sustainable bioenergy and advanced products from Cannabis/hemp biomass in Canada

  2022cites this paper
• Surviving in the Brine: A Multi-Omics Approach for Understanding the Physiology of the Halophile Fungus Aspergillus sydowii at Saturated NaCl Concentration

  2022cites this paper
• Advances in metabolic engineering of yeasts for the production of fatty acid-derived hydrocarbon fuels

  2022cites this paper
• Developments in Fatty Acid-Derived Insect Pheromone Production Using Engineered Yeasts

  2021cites this paper
• Trends in Synthetic Biology in the Bioeconomy of Non-food-Competing Biofuels

  2021influential citation
• Method Development for Comprehensive Lipidome Profiling of Cells using LC-MS

  2021cites this paper
• Metabolic engineering Yarrowia lipolytica for a dual biocatalytic system to produce fatty acid ethyl esters from renewable feedstock in situ and in one pot

  2021cites this paper
• Production of Biofuels From Biomass by Fungi

  2021cites this paper
• Bioengineered microbial platforms for biomass-derived biofuel production - A review.

  2021cites this paper
• Enhanced lipid accumulation in Metschnikowia pulcherrima using volatile fatty acids under non-sterile repeated batch cultivation

  2021cites this paper
• The Role of Metabolic Engineering Technologies for the Production of Fatty Acids in Yeast

  2021cites this paper
• Metabolic Engineering of Yeast for Enhanced Natural and Exotic Fatty Acid Production

  2021cites this paper
• Engineering of Saccharomyces cerevisiae for the accumulation of high amounts of triacylglycerol

  2021cites this paper
• Animal Fatty Acid Synthase: A Chemical Nanofactory.

  2021cites this paper
• Recombination machinery engineering facilitates metabolic engineering of the industrial yeast Pichia pastoris

  2021cites this paper
• Advances in developing metabolically engineered microbial platforms to produce fourth-generation biofuels and high-value biochemicals.

  2021cites this paper
• A novel oleaginous yeast Saccharomyces cerevisiae CU-TPD4 for lipid and biodiesel production.

  2021cites this paper
• Systematic Engineering of Saccharomyces cerevisiae for D-lactic Acid Production with Near Theoretical Yield.

  2021cites this paper
• Production of octanoic acid in Saccharomyces cerevisiae: Investigation of new precursor supply engineering strategies and intrinsic limitations

  2021cites this paper
• Microbial engineering to produce fatty alcohols and alkanes.

  2021cites this paper