The Ectodomain of a Novel Member of the Immunoglobulin Subfamily Related to the Poliovirus Receptor Has the Attributes of a Bona Fide Receptor for Herpes Simplex Virus Types 1 and 2 in Human Cells

No abstract is available for this paper.

• Publication year

  1998

• Venue

  Journal of Virology

• Publication date

  1998-12-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1128/JVI.72.12.9992-10002.1998PMID 9811737PMCID PMC110516
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• Entry of alphaherpesviruses mediated by poliovirus receptor-related protein 1 and poliovirus receptor.

  1998influential reference
• Normalization and subtraction: two approaches to facilitate gene discovery.

  1996cited by this paper
• Structure-function analysis of soluble forms of herpes simplex virus glycoprotein D

  1996cited by this paper
• Anti-idiotypic antibodies mimicking glycoprotein D of herpes simplex virus identify a cellular protein required for virus spread from cell to cell and virus-induced polykaryocytosis.

  1996cited by this paper
• Herpes simplex virus-1 entry into cells mediated by a novel member of the TNF/NGF receptor family.

  1996cited by this paper
• Complementary DNA characterization and chromosomal localization of a human gene related to the poliovirus receptor-encoding gene.

  1995influential reference
• Role of mannose-6-phosphate receptors in herpes simplex virus entry into cells and cell-to-cell transmission

  1995cited by this paper
• The human PRR2 gene, related to the human poliovirus receptor gene (PVR), is the true homolog of the murine MPH gene.

  1995influential reference
• RNA analysis using miniprep RNA in reverse transcription PCR.

  1994cited by this paper
• Mapping of herpes simplex virus 1 genes with mutations which overcome host restrictions to infection.

  1994influential reference
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  1994cited by this paper
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  1993cited by this paper
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  1990influential reference
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• Cellular receptor for poliovirus: molecular cloning, nucleotide sequence, and expression of a new member of the immunoglobulin superfamily.

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  1968cited by this paper
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