Membrane-associated RING-CH (MARCH) 8 mediates the ubiquitination and lysosomal degradation of the transferrin receptor

No abstract is available for this paper.

• Publication year

  2013

• Venue

  Journal of Cell Science

• Publication date

  2013-07-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1242/jcs.119909PMID 23606747
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• This information is current as Dendritic Cells in Regulating Antigen Presentation by Ubiquitination of CD 86 Is a Key Mechanism

  2011cited by this paper
• Ubiquitin-mediated Regulation of CD86 Protein Expression by the Ubiquitin Ligase Membrane-associated RING-CH-1 (MARCH1)*

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• CD83 increases MHC II and CD86 on dendritic cells by opposing IL-10–driven MARCH1-mediated ubiquitination and degradation

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• Endosomal transport via ubiquitination.

  2011cited by this paper
• Identification of SAMT family proteins as substrates of MARCH11 in mouse spermatids

  2011cited by this paper
• MARCH ubiquitin ligases alter the itinerary of clathrin-independent cargo from recycling to degradation

  2011influential reference
• Membrane-associated RING-CH 10 (MARCH10 Protein) Is a Microtubule-associated E3 Ubiquitin Ligase of the Spermatid Flagella*

  2011cited by this paper
• Proteome of ubiquitin/MVB pathway: possible involvement of iron‐induced ubiquitylation of transferrin receptor in lysosomal degradation

  2011cited by this paper
• Membrane-Associated RING-CH Proteins Associate with Bap31 and Target CD81 and CD44 to Lysosomes

  2010cited by this paper
• E3 ubiquitin ligases for MHC molecules.

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• The trafficking and regulation of membrane receptors by the RING-CH ubiquitin E3 ligases.

  2009cited by this paper
• HIV-1 Accessory Protein Vpu Internalizes Cell-surface BST-2/Tetherin through Transmembrane Interactions Leading to Lysosomes*

  2009cited by this paper
• Discrete Domains of MARCH1 Mediate Its Localization, Functional Interactions, and Posttranscriptional Control of Expression1

  2009influential reference
• The HLA-DRα Chain Is Modified by Polyubiquitination*

  2009cited by this paper
• RING domain E3 ubiquitin ligases.

  2009cited by this paper
• Differential MHC class II synthesis and ubiquitination confers distinct antigen-presenting properties on conventional and plasmacytoid dendritic cells

  2008cited by this paper
• MHC class II stabilization at the surface of human dendritic cells is the result of maturation-dependent MARCH I down-regulation

  2008cited by this paper
• Viral and cellular MARCH ubiquitin ligases and cancer.

  2008cited by this paper
• Biogenesis and function of multivesicular bodies.

  2007cited by this paper
• MARCH-XI, a Novel Transmembrane Ubiquitin Ligase Implicated in Ubiquitin-dependent Protein Sorting in Developing Spermatids*

  2007cited by this paper
• Ubiquitin-dependent sorting of integral membrane proteins for degradation in lysosomes.

  2007cited by this paper
• Proteasome-Independent Functions of Ubiquitin in Endocytosis and Signaling

  2007cited by this paper
• A novel family of membrane-bound E3 ubiquitin ligases.

  2006cited by this paper
• Role of ubiquitylation in cellular membrane transport.

  2006cited by this paper
• Downregulation of cell surface receptors by the K3 family of viral and cellular ubiquitin E3 ligases

  2005cited by this paper
• Downregulation of Major Histocompatibility Complex Class I by Human Ubiquitin Ligases Related to Viral Immune Evasion Proteins

  2004influential reference
• c-MIR, a Human E3 Ubiquitin Ligase, Is a Functional Homolog of Herpesvirus Proteins MIR1 and MIR2 and Has Similar Activity*

  2003cited by this paper
• Receptor downregulation and multivesicular-body sorting

  2002cited by this paper
• The ubiquitin-proteasome system and endocytosis.

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• Ubiquitin‐dependent internalization and down‐regulation of plasma membrane proteins

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• Transferrin receptor internalization sequence YXRF implicates a tight turn as the structural recognition motif for endocytosis.

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• Mechanisms of membrane protein turnover.

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• Identification of the iron-responsive element for the translational regulation of human ferritin mRNA.

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• Noncoding 3′ sequences of the transferrin receptor gene are required for mRNA regulation by iron.

  1987cited by this paper
• Primary structure of human transferrin receptor deduced from the mRNA sequence

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• pH and the recycling of transferrin during receptor-mediated endocytosis.

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• Internalization and processing of transferrin and the transferrin receptor in human carcinoma A431 cells

  1983cited by this paper
• Kinetics of internalization and recycling of transferrin and the transferrin receptor in a human hepatoma cell line. Effect of lysosomotropic agents.

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• Biosynthesis of the human transferrin receptor in cultured cells.

  1981cited by this paper
• Identification of transferrin receptors on the surface of human cultured cells.

  1979cited by this paper

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• Epsin1 enforces a condensation-dependent checkpoint for ubiquitylated cargo during clathrin-mediated endocytosis

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• African swine fever virus A179L inhibits interferon induced transmembrane protein 1 activation of NF-κB pathway

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• The E3 ubiquitin ligase MARCHF8 restricts HSV-1 infection by inhibiting replication of the viral genome

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• Transferrin receptor controls both autophagosome formation and closure via phosphatidylinositol 3-phosphate synthesis.

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• Research progress of deubiquitinating enzymes in cerebral ischemia-reperfusion injury

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• Genetic Markers of Postmortem Brain Iron

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• A pan-cancer analysis of MARCH8: molecular characteristics, clinical relevance, and immuno-oncology features

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• MARCH to combat Zika virus infection

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• Poly-ubiquitylated transmembrane proteins outcompete other cargo for limited space inside clathrin-coated vesicles

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• MARCH8-mediated ubiquitination regulates expression of the antiviral protein IFITM3

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• Poly-ubiquitylated transmembrane proteins outcompete other cargo for limited space inside clathrin-coated vesicles

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• Novel loci and biomedical consequences of iron homoeostasis variation

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• MARCH2, a T cell specific factor that restricts HIV-1 infection

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• Role of MARCH E3 ubiquitin ligases in cancer development

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• O-GlcNAcylation regulates the stability of transferrin receptor (TFRC) to control the ferroptosis in hepatocellular carcinoma cells

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• Further Characterization of the Antiviral Transmembrane Protein MARCH8

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• Membrane-Associated Ubiquitin Ligase RING Finger Protein 152 Orchestrates Melanogenesis via Tyrosinase Ubiquitination

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• Human MARCH1, 2, and 8 block Ebola virus envelope glycoprotein cleavage via targeting furin P domain

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• Tsg101 mimicry of canonical E2 enzymes underlies its role in ubiquitin signaling

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• Transferrin Receptor Protein 1 Is an Entry Factor for Rabies Virus

  2023cites this paper
• MARCH8 downregulation modulates profibrotic responses including myofibroblast differentiation.

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• NUF2 Drives Cholangiocarcinoma Progression and Migration via Inhibiting Autophagic Degradation of TFR1

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• The emerging roles of MARCH8 in viral infections: A double-edged Sword

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• Cardiac Iron Metabolism During Aging - Role of Inflammation and Proteolysis.

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  2022cites this paper
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  2020influential citation
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  2019cites this paper
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  2018cites this paper
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  2018cites this paper
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• Overview of the membrane-associated RING-CH (MARCH) E3 ligase family.

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