Modulation of Dengue Virus Infection in Human Cells by Alpha, Beta, and Gamma Interferons

No abstract is available for this paper.

• Publication year

  2000

• Venue

  Journal of Virology

• Publication date

  2000-06-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1128/JVI.74.11.4957-4966.2000PMID 10799569PMCID PMC110847
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Dengue virus infection of human skin fibroblasts in vitro production of IFN-β, IL-6 and GM-CSF

  2005cited by this paper
• Flavivirus entry into cultured mosquito cells and human peripheral blood monocytes

  2005cited by this paper
• Dengue-2 virus infection of human mononuclear cell lines and establishment of persistent infections

  2005cited by this paper
• Immunopathogenesis of Dengue hemorrhagic fever.

  1999cited by this paper
• Sequential production of cytokines by dengue virus‐infected human peripheral blood leukocyte cultures

  1999cited by this paper
• Application of molecular typing techniques in the 1998 dengue epidemic in Nicaragua.

  1999cited by this paper
• Dengue Virus Structural Differences That Correlate with Pathogenesis

  1999cited by this paper
• Fatal dengue hemorrhagic fever in Cuba, 1997.

  1999cited by this paper
• Early immune activation in acute dengue illness is related to development of plasma leakage and disease severity.

  1999cited by this paper
• Failure of secondary infection with American genotype dengue 2 to cause dengue haemorrhagic fever.

  1999cited by this paper
• New Mouse Model for Dengue Virus Vaccine Testing

  1999cited by this paper
• Molecular evolution of dengue type 2 virus in Thailand.

  1998cited by this paper
• Adaptation of Sindbis Virus to BHK Cells Selects for Use of Heparan Sulfate as an Attachment Receptor

  1998cited by this paper
• Analysis of antibody-independent binding of dengue viruses and dengue virus envelope protein to human myelomonocytic cells and B lymphocytes.

  1998cited by this paper
• Typing of Dengue Viruses in Clinical Specimens and Mosquitoes by Single-Tube Multiplex Reverse Transcriptase PCR

  1998cited by this paper
• How cells respond to interferons.

  1998influential reference
• Molecular mechanisms of interferon resistance mediated by viral-directed inhibition of PKR, the interferon-induced protein kinase.

  1998cited by this paper
• Comparative Study of Different Standardization Concepts in Quantitative Competitive Reverse Transcription-PCR Assays

  1998cited by this paper
• Study of Dengue Virus Infection in SCID Mice Engrafted with Human K562 Cells

  1998cited by this paper
• Dengue virus infectivity depends on envelope protein binding to target cell heparan sulfate

  1997cited by this paper
• Inhibition of Japanese encephalitis virus infection by nitric oxide: antiviral effect of nitric oxide on RNA virus replication

  1997cited by this paper
• Cellular responses to interferon-gamma.

  1997cited by this paper
• Origins of dengue type 2 viruses associated with increased pathogenicity in the Americas.

  1997cited by this paper
• Rapid competitive PCR determination of relative gene expression in limiting tissue samples.

  1996cited by this paper
• Differences in interferon alpha and beta signaling. Interferon beta selectively induces the interaction of the alpha and betaL subunits of the type I interferon receptor.

  1996cited by this paper
• Differences in Interferon α and β Signaling

  1996cited by this paper
• T cell activation in vivo by dengue virus infection.

  1995cited by this paper
• Lack of augmenting effect of interferon‐γ on dengue virus multiplication in human peripheral blood monocytes

  1995cited by this paper
• Therapy of acute and chronic viral hepatitis.

  1994cited by this paper
• Therapy of acute and chronic viral hepatitis.

  1994cited by this paper
• Dengue: the risk to developed and developing countries.

  1994cited by this paper
• Immunopathologic mechanisms of dengue hemorrhagic fever and dengue shock syndrome.

  1994cited by this paper
• High levels of interferon alpha in the sera of children with dengue virus infection.

  1993cited by this paper
• Activation of T lymphocytes in dengue virus infections. High levels of soluble interleukin 2 receptor, soluble CD4, soluble CD8, interleukin 2, and interferon-gamma in sera of children with dengue.

  1991cited by this paper
• Comparative Therapeutic Efficacy of Recombinant Interferons-α, -β, and -γ Against Alphatogavirus, Bunyavirus, Flavivirus, and Herpesvirus Infections

  1990cited by this paper
• Human immune responses to dengue viruses.

  1990cited by this paper
• Effect of Cytokines on Japanese Encephalitis Virus Production by Human Monocytes

  1990cited by this paper
• Human T cell responses to dengue virus antigens. Proliferative responses and interferon gamma production.

  1989cited by this paper
• Antibody, macrophages, dengue virus infection, shock, and hemorrhage: a pathogenetic cascade.

  1989cited by this paper
• Pathogenesis of dengue: challenges to molecular biology.

  1988influential reference
• Gamma interferon augments Fc gamma receptor-mediated dengue virus infection of human monocytic cells

  1988cited by this paper
• Production of interferon alpha by dengue virus-infected human monocytes.

  1988cited by this paper
• Induction of interferon alpha from human lymphocytes by autologous, dengue virus-infected monocytes

  1987cited by this paper
• The effect of interferon on flaviviruses in vitro: a preliminary study.

  1984cited by this paper
• The effect of interferon on Japanese encephalitis virus in vitro.

  1984cited by this paper
• Infection enhancement of dengue type 2 virus in the U-937 human monocyte cell line by antibodies to flavivirus cross-reactive determinants

  1982cited by this paper
• Enhancement of dengue virus infection in monocytes by flavivirus antisera.

  1980cited by this paper
• Antibody-enhanced dengue virus infection in primate leukocytes

  1977cited by this paper
• Single-step separation of red blood cells. Granulocytes and mononuclear leukocytes on discontinuous density gradients of Ficoll-Hypaque.

  1974cited by this paper
• Antibody response in dengue and dengue hemorrhagic fever.

  1967cited by this paper
• Antibody-dependent Enhancement of Dengue Human Igg Fc Receptor Ii Mediates

  year unknowninfluential reference

• Evaluating antiviral candidates for dengue virus infection: A review

  2026cites this paper
• Dengue and severe dengue

  2025cites this paper
• Mitochondria-dependent innate immunity: A potential therapeutic target in Flavivirus infection.

  2025cites this paper
• Nano-interventions for dengue: a comprehensive review of control, detection and treatment strategies

  2025cites this paper
• Dengue virus infection reprograms baseline innate immune gene expression.

  2025cites this paper
• Identifying a novel region in the Tembusu virus NS5 protein antagonizing type I interferon signaling

  2025cites this paper
• The pregnane X receptor is a novel host target for dengue virus infection that reprograms lipid metabolism and suppresses the immune response.

  2025cites this paper
• Megakaryocytic Differentiation Regulates the Permissiveness and Antiviral Response of the Megakaryocytic Erythroid Progenitor to Dengue Virus

  2025cites this paper
• Guaroa virus, a forgotten Latin American orthobunyavirus: A narrative review

  2025cites this paper
• Dengue virus-host interactions: Structural and mechanistic insights for future therapeutic strategies.

  2025cites this paper
• The interplay of co-infections in shaping COVID-19 severity: Expanding the scope beyond SARS-CoV-2.

  2024cites this paper
• Immunomodulation in dengue: towards deciphering dengue severity markers

  2024cites this paper
• Pathogenicity and transcriptomic resolution in dengue virus serotype 1 infected AGB6 mouse model

  2024cites this paper
• Innovations in dengue virus detection: An overview of conventional and electrochemical biosensor approaches

  2024cites this paper
• Exploring the therapeutic potential of DV-B-120 as an inhibitor of dengue virus infection

  2024influential citation
• HSPA13 modulates type I interferon antiviral pathway and NLRP3 inflammasome to restrict dengue virus infection in macrophages.

  2023cites this paper
• Mosquito-borne flaviviruses and type I interferon: catch me if you can!

  2023cites this paper
• Dengue Virus Infection of Human Retinal

  2023cites this paper
• A cellular screening platform, stably expressing DENV2 NS5, defines a novel anti-DENV mechanism of action of Apigenin based on STAT2 activation.

  2023cites this paper
• Insulin-mediated endothelin signaling is antiviral during West Nile virus infection

  2023influential citation
• Dengue Virus Infection of Human Retinal Müller Glial Cells

  2023cites this paper
• Differential Expression Patterns of Indoleamine 2,3-Dioxygenase 1 and Other Tryptophan and Arginine Catabolic Pathway Genes in Dengue Correlate with Clinical Severity-Pilot Study Results

  2023cites this paper
• Insulin-mediated endothelin signaling is antiviral during West Nile virus infection

  2023cites this paper
• Immune-Mediated Pathogenesis in Dengue Virus Infection

  2022cites this paper
• Innate and adaptive immune evasion by dengue virus

  2022cites this paper
• Innate Immune Response to Dengue Virus: Toll-like Receptors and Antiviral Response

  2022cites this paper
• Viral-Host Dependency Factors as Therapeutic Targets to Overcome Antiviral Drug-Resistance: A Focus on Innate Immune Modulation

  2022cites this paper
• Mapping of molecular interactions between human E3 ligase TRIM69 and Dengue virus NS3 protease using hydrogen–deuterium exchange mass spectrometry

  2022cites this paper
• Constitutive expression and distinct properties of IFN-epsilon protect the female reproductive tract from Zika virus infection

  2022cites this paper
• Single-cell temporal analysis of natural dengue infection reveals skin-homing lymphocyte expansion one day before defervescence

  2022cites this paper
• Immune profile and responses of a novel dengue DNA vaccine encoding an EDIII-NS1 consensus design based on Indo-African sequences

  2022cites this paper
• Dengue and COVID-19: two sides of the same coin

  2022cites this paper
• Lineage Replacement Associated with Fitness Gain in Mammalian Cells and Aedes aegypti: A Catalyst for Dengue Virus Type 2 Transmission

  2022cites this paper
• Cross-reactive antibodies facilitate innate sensing of dengue and Zika viruses.

  2022cites this paper
• Immune profile and responses of a novel Dengue DNA vaccine encoding EDIII-NS1 consensus design based on Indo-African sequences

  2021cites this paper
• Use of intravenous N-acetylcysteine in acute severe hepatitis due to severe dengue infection: a case series

  2021cites this paper
• Roles of Non-Structural Protein 4A in Flavivirus Infection

  2021cites this paper
• Dengue virus infection and virus-specific HLA-A2 restricted immune responses in humanized NOD-scid IL2rgammanull mice

  2021cites this paper
• Emergence of Dengue 4 as Dominant Serotype During 2017 Outbreak in South India and Associated Cytokine Expression Profile

  2021cites this paper
• Effect of IFN-γ +874 T/A polymorphism on clinical manifestations of dengue: a meta-analysis

  2021cites this paper
• Serum IL-18 Is a Potential Biomarker for Predicting Severe Dengue Disease Progression

  2021cites this paper
• Innate Immune Antagonism of Mosquito-Borne Flaviviruses in Humans and Mosquitoes

  2021cites this paper
• USP18 Mediates Interferon Resistance of Dengue Virus Infection

  2021cites this paper
• Recent Insights Into the Molecular Mechanism of Toll-Like Receptor Response to Dengue Virus Infection

  2021cites this paper
• Blood Levels of Galectin-9, an Immuno-Regulating Molecule, Reflect the Severity for the Acute and Chronic Infectious Diseases

  2021cites this paper
• Alteration of L-Dopa decarboxylase expression in SARS-CoV-2 infection and its association with the interferon-inducible ACE2 isoform

  2021influential citation
• Pathogenesis and virulence of flavivirus infections

  2021cites this paper
• Human Type I Interferon Antiviral Effects in Respiratory and Reemerging Viral Infections

  2020cites this paper
• Dengue Immunopathogenesis: A Crosstalk between Host and Viral Factors Leading to Disease: Part I - Dengue Virus Tropism, Host Innate Immune Responses, and Subversion of Antiviral Responses

  2020cites this paper
• Chimeric flavivirus enables evaluation of antibodies against dengue virus envelope protein in vitro and in vivo

  2020cites this paper
• Regulation of Host Innate Immunity by Non-Coding RNAs During Dengue Virus Infection

  2020cites this paper
• Association between interferon lambda 3 rs12979860 polymorphism and clinical outcome in dengue virus‐infected children

  2020cites this paper
• Chikungunya virus antagonizes cGAS-STING mediated type-I interferon responses by degrading cGAS

  2020cites this paper
• Modeling the intracellular dynamics of the dengue viral infection and the innate immune response.

  2020cites this paper
• Multivariate time-series analysis of biomarkers from a dengue cohort offers new approaches for diagnosis and prognosis

  2020cites this paper
• The Restrictome of Flaviviruses

  2020cites this paper
• Sequential MAVS- and MyD88/TRIF-signaling triggers anti-viral responses of tick-borne encephalitis virus-infected murine astrocytes

  2020cites this paper
• Mobilization and Activation of the Innate Immune Response to Dengue Virus

  2020cites this paper
• Human megakaryocytes possess intrinsic antiviral immunity through regulated induction of IFITM3.

  2019cites this paper
• Dengue and Zika Virus 5′ Untranslated Regions Harbor Internal Ribosomal Entry Site Functions

  2019cites this paper
• Transmembrane protein 2 inhibits Zika virus replication through activation of the Janus kinase/signal transducers and activators of transcription signaling pathway

  2019cites this paper
• Dengue and Zika virus 5’-UTRs harbor IRES functions

  2019cites this paper
• Evaluation of anti-dengue activity of Carica papaya aqueous leaf extract and its role in platelet augmentation

  2019cites this paper
• Simian Immunodeficiency Virus Infection of Rhesus Macaques Results in Delayed Zika Virus Clearance

  2019cites this paper
• Altered monocyte response to the dengue virus in those with varying severity of past dengue infection.

  2019cites this paper
• The Pathogenesis and Immune-Response in Dengue Haemorrhagic Fever

  2019cites this paper
• Infection of Aedes albopictus Mosquito C6/36 Cells with the wMelpop Strain of Wolbachia Modulates Dengue Virus-Induced Host Cellular Transcripts and Induces Critical Sequence Alterations in the Dengue Viral Genome

  2019cites this paper
• Characterisation of RIG-I-like receptor agonists for dengue virus therapy or vaccination

  2019influential citation
• Antiviral Effects of Clinically-Relevant Interferon-α and Ribavirin Regimens against Dengue Virus in the Hollow Fiber Infection Model (HFIM)

  2018cites this paper
• Studies on the virulence factor involved in the pathogenicity in tick-borne encephalitis virus infection

  2018cites this paper
• BALB/c mice infected with DENV-2 strain 66985 by the intravenous route display injury in the central nervous system

  2018cites this paper
• Gamma-Interferon Attenuates Yellow Fever Virus Vaccine Strain 17D

  2018cites this paper
• iPS cell serves as a source of dendritic cells for in vitro dengue virus infection model.

  2018cites this paper
• Drug repurposing of quinine as antiviral against dengue virus infection.

  2018cites this paper
• Simulation Model for Dynamics of Dengue with Innate and Humoral Immune Responses

  2018cites this paper
• Immune Response to Dengue and Zika.

  2018cites this paper
• Dengue virus and the host innate immune response

  2018cites this paper
• Interferon-Inducible Genes

  2018cites this paper
• Induction of anti‐viral genes mediated by humoral factors upon stimulation with Lactococcus lactis strain plasma results in repression of dengue virus replication in vitro

  2018cites this paper
• Human keratinocyte cultures (HaCaT) can be infected by DENV, triggering innate immune responses that include IFNλ and LL37.

  2018cites this paper
• Type I Interferons: Distinct Biological Activities and Current Applications for Viral Infection

  2018cites this paper
• Gamma-interferon exerts a critical early restriction on replication and dissemination of yellow fever virus vaccine strain 17D-204

  2018cites this paper
• High-dimensional CyTOF analysis of dengue virus-infected human DCs reveals distinct viral signatures.

  2017cites this paper
• IL-28 and IL-29 as protective markers in subject with dengue fever

  2017cites this paper
• An IRF-3-, IRF-5-, and IRF-7-Independent Pathway of Dengue Viral Resistance Utilizes IRF-1 to Stimulate Type I and II Interferon Responses.

  2017cites this paper
• Host cell responses to dengue virus infection

  2017cites this paper
• University of Groningen Suppression of chikungunya virus replication and differential innate responses of human peripheral blood mononuclear cells during co-infection with dengue virus

  2017cites this paper
• Evaluation of a Tetravalent DNA Vaccine against Dengue: Integrating Biochemical Studies on Dengue Virus Envelope Protein to a Domain-Based Antigen Design.

  2017cites this paper
• Host cell responses to dengue virus infection

  2017cites this paper
• Leptospirosis: Molecular trial path and immunopathogenesis correlated with dengue, malaria and mimetic hemorrhagic infections.

  2017cites this paper
• Serum from dengue virus-infected patients with and without plasma leakage differentially affects endothelial cells barrier function in vitro

  2017cites this paper
• Schisandrin A inhibits dengue viral replication via upregulating antiviral interferon responses through STAT signaling pathway

  2017cites this paper
• Zika Virus: The Agent and Its Biology, With Relevance to Pathology.

  2017cites this paper
• Evasion of Innate Immunity by Dengue Virus Non-Structural Proteins through Interfereing with Type I Interferon Production and Jak/STAT Signaling

  2017cites this paper
• Suppression of chikungunya virus replication and differential innate responses of human peripheral blood mononuclear cells during co-infection with dengue virus

  2017cites this paper
• Antagonism of type I interferon by flaviviruses.

  2017cites this paper
• Characterization of type I interferon responses in dengue and severe dengue in children in Paraguay.

  2017cites this paper
• Dengue virus NS2B protein targets cGAS for degradation and prevents mitochondrial DNA sensing during infection

  2017cites this paper
• Innate Immune Evasion Mediated by Flaviviridae Non-Structural Proteins

  2017cites this paper
• Interplay between Keratinocytes and Myeloid Cells Drives Dengue Virus Spread in Human Skin.

  2017cites this paper