Genetic and cytological characterization of the recombination protein RAD-51 in Caenorhabditis elegans

No abstract is available for this paper.

• Publication year

  2003

• Venue

  Chromosoma

• Publication date

  2003-04-08

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1007/s00412-003-0237-5PMID 12684824
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• [Caenorhabditis elegans].

  2020cited by this paper
• Conservation and Variability of Meiotic Processes — Lessons from the Unconventional Meiosis of C. elegans

  2004cited by this paper
• The synaptonemal complexes of Caenorhabditis elegans: the dominant him mutant mnT6 and pachytene karyotype analysis of the X-autosome translocation

  2004cited by this paper
• Roles for Caenorhabditis elegans rad-51 in meiosis and in resistance to ionizing radiation during development.

  2002influential reference
• Combined Functional Genomic Maps of the C. elegans DNA Damage Response

  2002cited by this paper
• Synapsis-dependent and -independent mechanisms stabilize homolog pairing during meiotic prophase in C. elegans.

  2002influential reference
• Nuclear reorganization and homologous chromosome pairing during meiotic prophase require C. elegans chk-2.

  2001influential reference
• Differential timing and control of noncrossover and crossover recombination during meiosis.

  2001cited by this paper
• Recombinational DNA double-strand breaks in mice precede synapsis

  2001cited by this paper
• A Caenorhabditis elegans cohesion protein with functions in meiotic chromosome pairing and disjunction.

  2001influential reference
• The C. elegans homolog of the p53 tumor suppressor is required for DNA damage-induced apoptosis.

  2001cited by this paper
• AtSPO11‐1 is necessary for efficient meiotic recombination in plants

  2001cited by this paper
• C. elegans mre-11 is required for meiotic recombination and DNA repair but is dispensable for the meiotic G(2) DNA damage checkpoint.

  2001influential reference
• The Rad51 and Dmc1 recombinases: a non-identical twin relationship.

  2001cited by this paper
• Caenorhabditis elegans p53: Role in Apoptosis, Meiosis, and Stress Resistance

  2001cited by this paper
• The single-end invasion: an asymmetric intermediate at the double-strand break to double-holliday junction transition of meiotic recombination.

  2001cited by this paper
• Meiotic DNA breaks associated with recombination in S. pombe.

  2000cited by this paper
• Zip3 provides a link between recombination enzymes and synaptonemal complex proteins.

  2000influential reference
• DNA damage-induced activation of p53 by the checkpoint kinase Chk2.

  2000cited by this paper
• A conserved checkpoint pathway mediates DNA damage--induced apoptosis and cell cycle arrest in C. elegans.

  2000influential reference
• Transgene-mediated cosuppression in the C. elegans germ line.

  2000cited by this paper
• The mouse Spo11 gene is required for meiotic chromosome synapsis.

  2000cited by this paper
• Caenorhabditis elegans msh-5 is required for both normal and radiation-induced meiotic crossing over but not for completion of meiosis.

  2000influential reference
• Multiple Pathways of Recombination Induced by Double-Strand Breaks in Saccharomyces cerevisiae

  1999cited by this paper
• Disruption of mRad50 causes embryonic stem cell lethality, abnormal embryonic development, and sensitivity to ionizing radiation.

  1999cited by this paper
• Rad51 and Dmc1 Form Mixed Complexes Associated with Mouse Meiotic Chromosome Cores and Synaptonemal Complexes

  1999influential reference
• A mouse homolog of the Saccharomyces cerevisiae meiotic recombination DNA transesterase Spo11p.

  1999cited by this paper
• Meiotic chromosomes: integrating structure and function.

  1999cited by this paper
• Mre11 is essential for the maintenance of chromosomal DNA in vertebrate cells

  1999cited by this paper
• Genetic control of programmed cell death in the Caenorhabditis elegans hermaphrodite germline.

  1999cited by this paper
• Three-Dimensional Microscopy of the Rad51 Recombination Protein during Meiotic Prophase

  1999influential reference
• Synapsis and chiasma formation in Caenorhabditis elegans require HIM-3, a meiotic chromosome core component that functions in chromosome segregation.

  1999cited by this paper
• Characterization of a Caenorhabditis elegans recA-like gene Ce-rdh-1 involved in meiotic recombination.

  1998influential reference
• Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

  1998cited by this paper
• Zip2, a meiosis-specific protein required for the initiation of chromosome synapsis.

  1998influential reference
• The Caenorhabditis elegansRAD51 homolog is transcribed into two alternative mRNAs potentially encoding proteins of different sizes

  1998influential reference
• Meiotic recombination in C. elegans initiates by a conserved mechanism and is dispensable for homologous chromosome synapsis.

  1998influential reference
• Meiosis-specific DNA double-strand breaks are catalyzed by Spo11, a member of a widely conserved protein family.

  1997cited by this paper
• Rad51 immunocytology in rat and mouse spermatocytes and oocytes

  1997cited by this paper
• Distribution of the Rad51 recombinase in human and mouse spermatocytes

  1997cited by this paper
• Meiotic chromosomes: it takes two to tango.

  1997cited by this paper
• An atypical topoisomerase II from archaea with implications for meiotic recombination

  1997cited by this paper
• Meiotic chromosomes: it takes two to tango

  1997cited by this paper
• Conditional gene targeted deletion by Cre recombinase demonstrates the requirement for the double-strand break repair Mre11 protein in murine embryonic stem cells.

  1997cited by this paper
• Partial rescue of the prophase I defects of Atm-deficient mice by p53 and p21 null alleles

  1997cited by this paper
• RecA-like proteins are components of early meiotic nodules in lily.

  1997cited by this paper
• Targeted disruption of the Rad51 gene leads to lethality in embryonic mice.

  1996cited by this paper
• Presynaptic association of Rad51 protein with selected sites in meiotic chromatin.

  1996cited by this paper
• A mutation in mouse rad51 results in an early embryonic lethal that is suppressed by a mutation in p53

  1996cited by this paper
• Caenorhabditis elegans : modern biological analysis of an organism

  1995cited by this paper
• Genetic balancers.

  1995cited by this paper
• Localization of RecA-like recombination proteins on chromosomes of the lily at various meiotic stages.

  1995influential reference
• Dynamic changes in Rad51 distribution on chromatin during meiosis in male and female vertebrates

  1995influential reference
• Initiation of recombination in Saccharomyces cerevisiae haploid meiosis.

  1994cited by this paper
• Initiation of meiotic recombination is independent of interhomologue interactions.

  1994cited by this paper
• RecA homologs Dmc1 and Rad51 interact to form multiple nuclear complexes prior to meiotic chromosome synapsis.

  1994influential reference
• Structural relationship of bacterial RecA proteins to recombination proteins from bacteriophage T4 and yeast.

  1993cited by this paper
• Similarity of the yeast RAD51 filament to the bacterial RecA filament.

  1993cited by this paper
• Meiotic nodules in vascular plants

  1993cited by this paper
• Rad51 protein involved in repair and recombination in S. cerevisiae is a RecA-like protein.

  1992cited by this paper
• The initiation of meiotic chromosome pairing: the cytological view.

  1990cited by this paper
• [Genetics of Caenorhabditis elegans].

  1989cited by this paper
• Synaptonemal complex spreading in Allium cepa and A. fistulosum

  1987cited by this paper
• Single-strand scissions of chromosomal DNA during commitment to recombination at meiosis.

  1975cited by this paper
• The genetics of Caenorhabditis elegans.

  1974cited by this paper
• A quick-freeze method for making smear slides permanent.

  1953cited by this paper

• Endogenous Expression and Subcellular Localization of Core Apoptosis Regulators Reveal Key Differences Between Embryonic and Germline Apoptosis in C. elegans

  2026cites this paper
• Overlapping and separable activities of BRA-2 and HIM-17 promote occurrence and regulation of pairing and synapsis during Caenorhabditis elegans meiosis

  2025cites this paper
• Damage-induced phosphorylation of BRC-1/BRD-1 in meiosis preserves germline integrity

  2025cites this paper
• Active maintenance of meiosis-specific chromosome structures in C. elegans by the deubiquitinase DUO-1

  2025cites this paper
• Neuronal oversight of germline small RNAs prevents heat-induced sterility in lab-domesticated Caenorhabditis elegans

  2025cites this paper
• NuRD chromatin remodeling contributes to repairing exogenous DSBs in the Caenorhabditis elegans germline

  2025cites this paper
• Kinetic analysis of strand invasion during C. elegans meiosis reveals similar rates of sister- and homolog-directed repair

  2025cites this paper
• Analysis of rad-51 separation of function allele suggests divergence of the synthesis-dependent strand annealing and double Holliday junction pathways prior to RAD-51 filament disassembly

  2025cites this paper
• The chromatin-associated 53BP1 ortholog, HSR-9, regulates recombinational repair and X chromosome segregation in the Caenorhabditis elegans germ line.

  2024cites this paper
• NuRD chromatin remodeling is required to repair exogenous DSBs in the Caenorhabditis elegans germline

  2024cites this paper
• The chromatin-associated 53BP1 ortholog, HSR-9, regulates recombinational repair and X chromosome segregation in the Caenorhabditis elegans germ line

  2024cites this paper
• ATM signaling modulates cohesin behavior in meiotic prophase and proliferating cells

  2023cites this paper
• Divergence and conservation of the meiotic recombination machinery

  2023cites this paper
• GRAS-1 is a novel regulator of early meiotic chromosome dynamics in C. elegans

  2023cites this paper
• Loss of NSE-4 Perturbs Genome Stability and DNA Repair in Caenorhabditis elegans

  2022cites this paper
• R-loop-induced irreparable DNA damage evades checkpoint detection in the C. elegans germline

  2022cites this paper
• Inheritance of paternal DNA damage by histone-mediated repair restriction

  2022cites this paper
• Disparate roles for C. elegans DNA translocase paralogs RAD-54.L and RAD-54.B in meiotic prophase germ cells

  2022cites this paper
• Release of CHK-2 from PPM-1.D anchorage schedules meiotic entry

  2022influential citation
• The topoisomerase 3 zinc finger domain cooperates with the RMI1 scaffold to promote stable association of the BTR complex to recombination intermediates in the Caenorhabditis elegans germline

  2022cites this paper
• Phosphorylation of HORMA-domain protein HTP-3 at Serine 285 is dispensable for crossover formation

  2022cites this paper
• Somatic PMK-1/p38 signaling links environmental stress to germ cell apoptosis and heritable euploidy

  2022cites this paper
• GRAS-1 is a conserved novel regulator of early meiotic chromosome dynamics in C. elegans

  2022cites this paper
• Differential requirement for BRCA1-BARD1 E3 ubiquitin ligase activity in DNA damage repair and meiosis in the Caenorhabditis elegans germ line

  2022cites this paper
• Pseudokinase HPO-11 inhibits nonsense-mediated decay to ensure genome stability in C. elegans

  2022cites this paper
• Meiotic dysfunction accelerates somatic aging in Caenorhabditis elegans

  2022cites this paper
• Visualizing and quantifying molecular and cellular processes in C. elegans using light microscopy.

  2022cites this paper
• OsRAD51 Plays a Vital Role in Promoting Homologous Recombination in Rice Meiosis

  2022cites this paper
• PARG and BRCA1–BARD1 cooperative function regulates DNA repair pathway choice during gametogenesis

  2022cites this paper
• PARG establishes a functional module with BRCA1-BARD1 that controls DNA repair pathway choice during gametogenesis

  2022cites this paper
• Bisection of the X chromosome disrupts the initiation of chromosome silencing during meiosis in Caenorhabditis elegans

  2021cites this paper
• Caenorhabditis elegans DSB-3 reveals conservation and divergence among protein complexes promoting meiotic double-strand breaks

  2021cites this paper
• Defining meiotic recombination landscape in tomato

  2021cites this paper
• Aging Negatively Impacts DNA Repair and Bivalent Formation in the C. elegans Germ Line

  2021cites this paper
• Robust designation of meiotic crossover sites by CDK-2 through phosphorylation of the MutSγ complex

  2021cites this paper
• Caenorhabditis elegans RMI2 functional homolog-2 (RMIF-2) and RMI1 (RMH-1) have both overlapping and distinct meiotic functions within the BTR complex

  2021cites this paper
• C. elegans DSB-3 Reveals Conservation and Divergence among Protein Complexes Promoting Meiotic Double-Strand Breaks

  2021cites this paper
• The CHK-2 antagonizing phosphatase PPM-1.D regulates meiotic entry via catalytic and non-catalytic activities

  2021influential citation
• C. elegans THSC/TREX-2 deficiency causes replication stress and genome instability.

  2021cites this paper
• DNA repair, recombination, and damage signaling

  2021cites this paper
• DNA damage signaling regulates cohesin stabilization and promotes meiotic chromosome axis morphogenesis

  2021cites this paper
• Genome stability in Caenorhabditis elegans

  2021cites this paper
• Detection of DSBs in C. elegans Meiosis.

  2021cites this paper
• DNA topoisomerase 3 is required for efficient germ cell quality control

  2021cites this paper
• Review of Biological Effects of Acute and Chronic Radiation Exposure on Caenorhabditis elegans

  2021cites this paper
• In vivo analysis of FANCD2 recruitment at meiotic DNA breaks in Caenorhabditis elegans

  2020cites this paper
• Poly(ADP-ribose) glycohydrolase promotes formation and homology-directed repair of meiotic DNA double-strand breaks independent of its catalytic activity

  2020cites this paper
• Oocyte aging is controlled by mitogen‐activated protein kinase signaling

  2020cites this paper
• Chromosome Integrity is Required for the Initiation of Meiotic Sex Chromosome Inactivation in Caenorhabditis elegans

  2020cites this paper
• RPA complexes in Caenorhabditis elegans meiosis; unique roles in replication, meiotic recombination and apoptosis

  2020cites this paper
• Poly(ADP-ribose) glycohydrolase coordinates meiotic DNA double-strand break induction and repair independent of its catalytic activity

  2020cites this paper
• Chromosome-autonomous feedback downregulates meiotic DSB competence upon synaptonemal complex formation

  2020cites this paper
• Recruitment of MRE-11 to complex DNA damage is modulated by meiosis-specific chromosome organization

  2020cites this paper
• Elevated Temperatures Cause Transposon-Associated DNA Damage in C. elegans Spermatocytes.

  2020cites this paper
• Synaptonemal Complex Central Region Proteins Promote Localization of Pro-crossover Factors to Recombination Events During Caenorhabditis elegans Meiosis

  2019cites this paper
• A DNA repair protein and histone methyltransferase interact to promote genome stability in the Caenorhabditis elegans germ line

  2019cites this paper
• Progression of Meiosis Is Coordinated by the Level and Location of MAPK Activation Via OGR-2 in Caenorhabditis elegans

  2019influential citation
• me101 is a new allele of rad-51

  2019cites this paper
• Defining the influence of Rad51 and Dmc1 lineage-specific amino acids on genetic recombination

  2019cites this paper
• PUFA protection against 60 Co γ-ray-induced abnormal expression of DNA damage-related genes in C . elegans

  2019cites this paper
• A Meiotic Checkpoint Alters Repair Partner Bias to Permit Inter-sister Repair of Persistent DSBs

  2019cites this paper
• ALG-2/AGO-Dependent mir-35 Family Regulates DNA Damage-Induced Apoptosis Through MPK-1/ERK MAPK Signaling Downstream of the Core Apoptotic Machinery in Caenorhabditis elegans

  2019cites this paper
• MRG‐1 is required for both chromatin‐based transcriptional silencing and genomic integrity of primordial germ cells in Caenorhabditis elegans

  2019cites this paper
• PCH-2 collaborates with CMT-1 to proofread meiotic homolog interactions

  2019cites this paper
• Antioxidant CoQ10 Restores Fertility by Rescuing Bisphenol A-Induced Oxidative DNA Damage in the Caenorhabditis elegans Germline

  2019cites this paper
• Visualization and Quantification of Transposon Activity in Caenorhabditis elegans RNAi Pathway Mutants

  2019cites this paper
• Visualization and quantification of transposon activity in C . elegans RNAi pathway mutants

  2019cites this paper
• FUNCTIONAL INSIGHTS INTO RAD51 REGULATORY PROTEINS IN HOMOLOGOUS RECOMBINATION

  2019cites this paper
• Reduction of mRNA export unmasks different tissue sensitivities to low mRNA levels during Caenorhabditis elegans development

  2019cites this paper
• Natural Genetic Variation in a Multigenerational Phenotype in C. elegans.

  2018cites this paper
• A Role in Apoptosis Regulation for the rad-51 Gene of Caenorhabditis elegans

  2018influential citation
• University of Dundee The conserved LEM-3 / Ankle 1 nuclease is involved in the combinatorial regulation of meiotic recombination repair and chromosome segregation in Caenorhabditis elegans

  2018cites this paper
• Meiotic Double-Strand Break Proteins Influence Repair Pathway Utilization

  2018cites this paper
• The BRCA1-BARD1 complex associates with the synaptonemal complex and pro-crossover factors and influences RAD-51 dynamics during Caenorhabditis elegans meiosis

  2018cites this paper
• Maintenance of Genome Integrity by Mi2 Homologs CHD-3 and LET-418 in Caenorhabditis elegans

  2018cites this paper
• A simple answer to complex questions: Caenorhabditis elegans as an experimental model for examining the DNA damage response and disease genes

  2018cites this paper
• The tumor suppressor BRCA1-BARD1 complex localizes to the synaptonemal complex and regulates recombination under meiotic dysfunction in Caenorhabditis elegans

  2018cites this paper
• Characterization of interplay among DNA repair, histone H3 lysine 9 dimethylation and small interfering RNA pathway in Caenorhabditis elegans

  2018cites this paper
• VIG-1 is required for maintenance of genome stability in Caenorhabditis elegans

  2018cites this paper
• Interdependent and separable functions of Caenorhabditis elegans MRN-C complex members couple formation and repair of meiotic DSBs

  2018influential citation
• BRCA1-BARD1 associate with the synaptonemal complex and pro-crossover factors and influence RAD-51 dynamics during Caenorhabditis elegans meiosis

  2018cites this paper
• C. elegans ZHP-4 is required at multiple distinct steps in the formation of crossovers and their transition to segregation competent chiasmata

  2018cites this paper
• The Caenorhabditis elegans RAD-51 isoform A is required for the induction of DNA-damage-dependent apoptosis

  2017influential citation
• Discovery and Characterization of Novel Sperm Development Patterns in the Nematode Rhabditis Sp. Sb347

  2017cites this paper
• Interdependent and separable functions of C. elegans MRN-C complex members couple formation and repair of meiotic DSBs

  2017cites this paper
• Depletion of cdc‐25.3, a Caenorhabditis elegans orthologue of cdc25, increases physiological germline apoptosis

  2017cites this paper
• Dynamic Architecture of DNA Repair Complexes and the Synaptonemal Complex at Sites of Meiotic Recombination

  2017cites this paper
• The conserved LEM-3/Ankle1 nuclease is involved in the combinatorial regulation of meiotic recombination repair and chromosome segregation in Caenorhabditis elegans

  2017cites this paper
• The tales of two organic cation transporters, OCT-1 and OCT-2, in Caenorhabditis elegans

  2017cites this paper
• DPFF‐1 transcription factor deficiency causes the aberrant activation of MPK‐1 and meiotic defects in the Caenorhabditis elegans germline

  2017cites this paper
• Noncanonical meiosis in the nematode Caenorhabditis elegans as a model for studying the molecular bases of the homologous chromosome synapsis, crossing over, and segregation

  2017cites this paper
• Transgenerational effects of proton beam irradiation on Caenorhabditis elegans germline apoptosis.

  2017cites this paper
• Investigating Heat Shock Induced Double Strand Breaks in Caenorhabditis elegans Spermatocyte

  2017influential citation
• The C. elegans SET-2/SET1 histone H3 Lys4 (H3K4) methyltransferase preserves genome stability in the germline.

  2017cites this paper
• A Role for the Nonsense-Mediated mRNA Decay Pathway in Maintaining Genome Stability in Caenorhabditis elegans

  2017cites this paper
• A role for the nonsense-mediated mRNA decay pathway in maintaining genome stability in C . elegans

  2017cites this paper
• Distinct unfolded protein responses mitigate or mediate effects of nonlethal deprivation of C. elegans sleep in different tissues

  2017cites this paper
• JMJD-5/KDM8 regulates H3K36me2 and is required for late steps of homologous recombination and genome integrity

  2017cites this paper
• A novel approach using C. elegans DNA damage-induced apoptosis to characterize the dynamics of uptake transporters for therapeutic drug discoveries

  2016cites this paper
• The SMC-5/6 Complex and the HIM-6 (BLM) Helicase Synergistically Promote Meiotic Recombination Intermediate Processing and Chromosome Maturation during Caenorhabditis elegans Meiosis

  2016cites this paper