Buffer agents do not reverse intramyocardial acidosis during cardiac resuscitation.

No abstract is available for this paper.

• Publication year

  1990

• Venue

  Circulation

• Publication date

  1990-05-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1161/01.CIR.81.5.1660PMID 2158865
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Effects of acidosis on myocardial contractility and metabolism.

  2009cited by this paper
• Cardiac effects of carbon dioxide-consuming and carbon dioxide-generating buffers during cardiopulmonary resuscitation.

  1990cited by this paper
• Myocardial acidosis associated with CO2 production during cardiac arrest and resuscitation.

  1989cited by this paper
• Arterial PCO2 as an indicator of systemic perfusion during cardiopulmonary resuscitation.

  1989cited by this paper
• Effects of Tromethamine and Sodium Bicarbonate Buffers During Cardiac Resuscitation

  1988cited by this paper
• Failure of epinephrine to improve the balance between myocardial oxygen supply and demand during closed-chest resuscitation in dogs.

  1988cited by this paper
• Intracellular pH and inorganic phosphate content of heart in vivo: a 31P-NMR study.

  1988cited by this paper
• Continuous measurement of intramyocardial pH: correlation to functional recovery following normothermic and hypothermic global ischemia.

  1986cited by this paper
• Arteriovenous carbon dioxide and pH gradients during cardiac arrest.

  1986cited by this paper
• Failure of sodium bicarbonate to improve resuscitation from ventricular fibrillation in dogs.

  1986cited by this paper
• Predictive indices of successful cardiac resuscitation after prolonged arrest and experimental cardiopulmonary resuscitation.

  1985cited by this paper
• The Significance of the Late Fall in Myocardial Pco2and Its Relationship to Myocardial pH after Regional Coronary Occlusion in the Dog

  1985cited by this paper
• The relationships of high energy phosphates, tissue pH, and regional blood flow to diastolic distensibility in the ischemic dog myocardium.

  1985cited by this paper
• Intrapulmonary epinephrine during prolonged cardiopulmonary resuscitation: improved regional blood flow and resuscitation in dogs.

  1984cited by this paper
• Prognostic and therapeutic importance of the aortic diastolic pressure in resuscitation from cardiac arrest

  1984cited by this paper
• First report of intramyocardial pH in man: I. Methodology and initial results.

  1984cited by this paper
• Coronary blood flow during cardiopulmonary resuscitation in swine.

  1984cited by this paper
• Systemic effects of NaHCO3 in experimental lactic acidosis in dogs.

  1982cited by this paper
• Treatment of lactic acidosis with dichloroacetate in dogs.

  1982cited by this paper
• Myocardial pH during regional ischemia: evaluation of a fiber-optic photometric probe.

  1982cited by this paper
• Rate of Rise of Myocardial PCO2 during Early Myocardial Ischemia in the Dog

  1979cited by this paper
• Studies of acidosis in the ischaemic heart by phosphorus nuclear magnetic resonance.

  1979cited by this paper
• Intramyocardial pH as an index of myocardial metabolism during cardiac surgery.

  1979cited by this paper
• Effect of pH on ionic exchange and function in rat and rabbit myocardium.

  1975cited by this paper
• Intramyocardial carbon dioxide tension. A guide to the safe period of anoxic arrest of the heart.

  1974cited by this paper
• Intramyocardial gas tensions in the canine heart during anoxic cardiac arrest.

  1972cited by this paper
• Cardiac arrest. Report of application of external cardiac massage on 118 patients.

  1961cited by this paper
• Closed-chest cardiac massage.

  1960cited by this paper
• On the significance of carbon dioxide for the heart beat

  1910cited by this paper

• Cardiac Arrest Pharmacopeia: A Personalized Approach to Drug Administration During Cardiopulmonary Resuscitation.

  2025cites this paper
• Why physicians use sodium bicarbonate during cardiac arrest: A cross-sectional survey study of adult and pediatric clinicians

  2024cites this paper
• Adverse Impact of Sodium Bicarbonate Administration on Multiple Outcomes in Acute Pancreatitis Patients With Hyperlactatemia

  2023cites this paper
• Fluid Therapy During Cardiopulmonary Resuscitation

  2021cites this paper
• Resuscitation 2020: Proceedings From the NeoHeart 2020 International Conference

  2021cites this paper
• The effects of sodium bicarbonate infusion on cerebrovascular function in newborn pigs

  2021cites this paper
• "Regulatory Roles for miR-126 in Inflammatory Response and Programmed Death of Cardiac Myocytes Driven by Acidosis During Simulated Ischemia"

  2021cites this paper
• Lactic Acidosis and The Role of Sodium Bicarbonate: A Narrative Opinion.

  2020cites this paper
• Metabolic Acidosis

  2019cites this paper
• Uses and misuses of sodium bicarbonate in the neonatal intensive care unit.

  2017cites this paper
• Cardiopulmonary resuscitation

  2017cites this paper
• Drug therapy in cardiac arrest: a review of the literature.

  2016cites this paper
• Adverse postresuscitation myocardial effects elicited by buffer-induced alkalemia ameliorated by NHE-1 inhibition in a rat model of ventricular fibrillation.

  2016influential citation
• A tourniquet assisted cardiopulmonary resuscitation augments myocardial perfusion in a porcine model of cardiac arrest.

  2015cites this paper
• Role of NHE1 in the Cellular Dysfunction of Acute Metabolic Acidosis

  2014cites this paper
• ИНФУЗИОННЫЕ АНТИГИПОКСАНТЫ ПРИ КРИТИЧЕСКИХ СОСТОЯНИЯХ У ДЕТЕЙ

  2014cites this paper
• Metabolic engineering of lactate dehydrogenase rescues mice from acidosis

  2014cites this paper
• Acid-Base Disorders in the PICU

  2014cites this paper
• Neonatal Assessment and Resuscitation

  2013cites this paper
• ФИЗИОЛОГИЯ ЧЕЛОВЕКА И ЖИВОТНЫХ HUMAN AND ANIMAL PHYSIOLOGY

  2013cites this paper
• Core Concepts and Treatment of Metabolic Acidosis

  2013cites this paper
• Infusing Sodium Bicarbonate Suppresses Hydrogen Peroxide Accumulation and Superoxide Dismutase Activity in Hypoxic-Reoxygenated Newborn Piglets

  2012cites this paper
• Sodium Bicarbonate Use in the Treatment of Acute Neonatal Lactic Acidosis

  2011cites this paper
• Max Harry Weil: a tribute from the Italian research fellows.

  2011cites this paper
• Slowing of Electrical Activity in Ventricular Fibrillation is Not Associated with Increased Defibrillation Energies in the Isolated Rabbit Heart

  2011cites this paper
• Useless Perinatal Therapies

  2010cites this paper
• Cardiopulmonary Resuscitation: Basic and Advanced Life Support

  2010cites this paper
• Part 11: Neonatal resuscitation: 2010 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations.

  2010cites this paper
• A Survey of Intravenous Sodium Bicarbonate in Neonatal Asphyxia among European Neonatologists: Gaps between Scientific Evidence and Clinical Practice

  2010cites this paper
• The role of resuscitation drugs and placental transfusion in the delivery room management of newborn infants.

  2008cites this paper
• Sodium Bicarbonate: Basically Useless Therapy

  2008cites this paper
• Chapter 1 – Cardiac Arrest and Cardiopulmonary Resuscitation

  2008cites this paper
• Case files of the Medical Toxicology Fellowship at the Toxikon Consortium in Chicago: Cocaine-associated wide-complex dysrhythmias and cardiac arrest— treatment nuances and controversies

  2008cites this paper
• Hypoxia in human NT2-N neurons : The role of acidosis, mitochondria and inflammation

  2008cites this paper
• Vascular access and drug therapy in pediatric resuscitation.

  2008cites this paper
• CO2: friend or foe?

  2007cites this paper
• Pharmacotherapy Considerations in Advanced Cardiac Life Support

  2006cites this paper
• Chapter 61 – Acid-Base Disorders

  2006cites this paper
• Use of high-dose epinephrine and sodium bicarbonate during neonatal resuscitation: is there proven benefit?

  2006cites this paper
• Sodium bicarbonate infusion during resuscitation of infants at birth.

  2006cites this paper
• Metabolic acidosis: pathophysiology, diagnosis and management.

  2006cites this paper
• Myocardial Dysfunction Postresuscitation

  2005cites this paper
• Physiology of Ventilation During Cardiac Arrest

  2005cites this paper
• Pharmacological Resuscitation Interventions

  2005cites this paper
• Cardiopulmonary Cerebral Resuscitation : Techniques

  2005cites this paper
• Animal Model of Cardiac Arrest

  2005cites this paper
• Etiology, Electrophysiology, Myocardial Energy Mechanics, and Treatment of Bradyasystole

  2005cites this paper
• Bench-to-bedside review: Treating acid–base abnormalities in the intensive care unit – the role of buffers

  2004cites this paper
• Cardiopulmonary cerebral resuscitation: emergency drugs and postresuscitative care

  2004cites this paper
• A randomized controlled trial of sodium bicarbonate in neonatal resuscitation-effect on immediate outcome.

  2004cites this paper
• Cardiopulmonary Cerebral Resuscitation: Techniques*

  2004cites this paper
• Management of the patient with an open abdomen: techniques in temporary and definitive closure.

  2004cites this paper
• Medikamentöse Therapie bei der kardiopulmonalen Reanimation

  2003cites this paper
• [Drug therapy during CPR].

  2003cites this paper
• Electrophysiologic and Hemodynamic Effects of Sodium Bicarbonate in a Canine Model of Severe Cocaine Intoxication

  2003cites this paper
• 11A Antenatal imaging and therapy

  2003cites this paper
• Neugeborenenerstversorgung und Reanimation

  2002cites this paper
• [Neonatal assessment and resuscitation. Current guidelines of the ICOR Pediatric Working Group].

  2002cites this paper
• Treatment of Acidosis: Sodium Bicarbonate and Other Drugs

  2002cites this paper
• Prehospital ACLS--does it work?

  2002cites this paper
• Neonatal resuscitation guidelines 2000: framework for practice

  2002cites this paper
• Pharmacotherapy during CPR

  2002cites this paper
• Rapid correction of early metabolic acidaemia in comparison with placebo, no intervention or slow correction in LBW infants.

  2002cites this paper
• [Drug therapy in cardiopulmonary resuscitation].

  2001cites this paper
• Pediatric resuscitation outside the operating room.

  2001cites this paper
• Use of base in the treatment of severe acidemic states.

  2001cites this paper
• Medications during resuscitation -- what is the evidence?

  2001cites this paper
• Pharmakotherapie bei der kardiopulmonalen Reanimation

  2001cites this paper
• Sodium bicarbonate for the treatment of lactic acidosis.

  2000cites this paper
• International guidelines for neonatal resuscitation: an excerpt from the guidelines 2000 for cardiopulmonary resuscitation and emergency cardiovascular care: international consensus on science

  2000cites this paper
• A new phased chest and abdominal compression-decompression cardiopulmonary device holds promise for use in humans.

  2000cites this paper
• Management of cardiopulmonary resuscitation.

  2000cites this paper
• Cardiopulmonary Resuscitation : Update , Controversies and New Advances Update

  2000cites this paper
• Cardiopulmonary resuscitation.

  2000cites this paper
• International Guidelines for Neonatal Resuscitation: An excerpt from the Guidelines 2000 for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care: International Consensus on Science. Contributors and Reviewers for the Neonatal Resuscitation Guidelines.

  2000cites this paper
• Damage control in trauma surgery

  2000cites this paper
• Part 11: neonatal resuscitation. European Resuscitation Council.

  2000cites this paper
• Tromethamine buffer modifies the depressant effect of permissive hypercapnia on myocardial contractility in patients with acute respiratory distress syndrome.

  2000cites this paper
• Cardiopulmonary resuscitation: update, controversies and new advances.

  1999cites this paper
• Acidosis during cardiac arrest: a manifestation of inadequate perfusion.

  1999cites this paper
• Combined effects of buffer and adrenergic agents on postresuscitation myocardial function.

  1999influential citation
• Differential Diagnosis and Treatment of Acidosis

  1999cites this paper
• Medication use in neonatal resuscitation.

  1999cites this paper
• Buffer treatment for cardiac resuscitation: putting the cart before the horse?

  1999cites this paper
• The use of acid buffers during cardiopulmonary resuscitation: a time to change again?

  1999cites this paper
• Tribonat--a comprehensive summary of its properties.

  1999cites this paper
• Flow requirements in ventricular fibrillation: An in vivo nuclear magnetic resonance analysis of the left ventricular high-energy phosphate pool.

  1999cites this paper
• Quels sont les moyens symptomatiques de corriger une acidose métabolique

  1999cites this paper
• Déséquilibres acidobasique et métabolique des arrêts circulatoires extrahospitaliers analyse biologique de 11 cas

  1998cites this paper
• Efficacy of buffers in the management of cardiac arrest.

  1998cites this paper
• Management of life-threatening acid-base disorders. Second of two parts.

  1998cites this paper
• [Preclinical blood gas analysis. 1. The value of preclinical blood gas analysis].

  1998cites this paper
• Die präklinische Blutgasanalyse Teil 1: Der Stellenwert der präklinischen Blutgasanalyse

  1998cites this paper
• Resuscitation at birth

  1998cites this paper
• 'Out-of-hospital cardiac arrests' treated by the West Midlands Ambulance Service over a 2-year period.

  1998cites this paper
• Management of life-threatening acid-base disorders. First of two parts.

  1998cites this paper
• Comparison of sodium bicarbonate, Carbicarb, and THAM during cardiopulmonary resuscitation in dogs.

  1998cites this paper
• Alkaline buffers for correction of metabolic acidosis during cardiopulmonary resuscitation with focus on Tribonat--a review.

  1998cites this paper
• Correction of acid-base derangements

  1998cites this paper
• Therapy of Lactic Acidosis

  1998cites this paper