Pathophysiology and therapy of pruritus in allergic and atopic diseases

No abstract is available for this paper.

• Publication year

  2010

• Venue

  Allergy. European Journal of Allergy and Clinical Immunology

• Publication date

  2010-07-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1111/j.1398-9995.2010.01995.xPMID 20384615
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Postoperative analgesia after radical prostatectomy with high-dose intrathecal morphine and intravenous naloxone: a retrospective review.

  2018cited by this paper
• Essential Aspects of Atopic Dermatitis

  2011cited by this paper
• Atopic dermatitis: a review of topical treatment options

  2010cited by this paper
• The safety and efficacy of pimecrolimus, 1%, cream for the treatment of Netherton syndrome: results from an exploratory study.

  2010cited by this paper
• Dorsal horn neurons expressing NK-1 receptors mediate scratching in rats

  2010cited by this paper
• The histamine H4 receptor mediates inflammation and pruritus in Th2-dependent dermal inflammation.

  2010cited by this paper
• Atopic eczema or atopiform dermatitis

  2010cited by this paper
• Effects of Atypical κ-Opioid Receptor Agonists on Intrathecal Morphine-Induced Itch and Analgesia in Primates

  2009cited by this paper
• Cellular Basis of Itch Sensation

  2009cited by this paper
• Case studies assessing a new skin barrier repair cream for the treatment of atopic dermatitis.

  2009cited by this paper
• Successful treatment of lichen amyloidosus associated with atopic dermatitis using a combination of narrowband ultraviolet B phototherapy, topical corticosteroids and an antihistamine

  2009cited by this paper
• Interleukin (IL)‐31 induces pro‐inflammatory cytokines in human monocytes and macrophages following stimulation with staphylococcal exotoxins

  2009cited by this paper
• Twice‐daily versus Once‐daily Applications of Pimecrolimus Cream 1% for the Prevention of Disease Relapse in Pediatric Patients with Atopic Dermatitis

  2009cited by this paper
• Impact of the Gly573Ser substitution in TRPV3 on the development of allergic and pruritic dermatitis in mice.

  2009cited by this paper
• Efficacy of a lipid-based barrier repair formulation in moderate-to-severe pediatric atopic dermatitis.

  2009cited by this paper
• Sensory neuron-specific GPCR Mrgprs are itch receptors mediating chloroquine-induced pruritus.

  2009cited by this paper
• Itching for insight.

  2009cited by this paper
• Pain: Itch without pain—a labeled line for itch sensation?

  2009cited by this paper
• Onset and duration of action of topical antihistamine: a study of histamine skin test response

  2008cited by this paper
• Proteinase-activated receptor-2 mediates itch: a novel pathway for pruritus in human skin.

  2008cited by this paper
• Histamine in the nervous system.

  2008cited by this paper
• Neurophysiological and neurochemical basis of modern pruritus treatment

  2008cited by this paper
• TRPs in our senses.

  2008cited by this paper
• Human Keratinocytes Are Vanilloid Resistant

  2008cited by this paper
• A gastrin-releasing peptide receptor mediates the itch sensation in the spinal cord

  2007cited by this paper
• Transient receptor potential cation channels in disease.

  2007cited by this paper
• Neuronal control of skin function: the skin as a neuroimmunoendocrine organ.

  2006cited by this paper
• Frontiers in pruritus research: scratching the brain for more effective itch therapy.

  2006cited by this paper
• IL-31: a new link between T cells and pruritus in atopic skin inflammation.

  2006cited by this paper
• Small molecule vanilloid TRPV1 receptor antagonists approaching drug status: can they live up to the expectations?

  2006cited by this paper
• Efficacy and tolerability of topical pimecrolimus and tacrolimus in the treatment of atopic dermatitis: meta-analysis of randomised controlled trials

  2005cited by this paper
• Distribution of cannabinoid receptor 1 (CB1) and 2 (CB2) on sensory nerve fibers and adnexal structures in human skin.

  2005cited by this paper
• How best to fight that nasty itch – from new insights into the neuroimmunological, neuroendocrine, and neurophysiological bases of pruritus to novel therapeutic approaches

  2005cited by this paper
• Mechanisms by which psychologic stress alters cutaneous permeability barrier homeostasis and stratum corneum integrity.

  2005cited by this paper
• The mode of topical immunomodulators in the immunological network of atopic dermatitis

  2005cited by this paper
• Noxious heat and scratching decrease histamine-induced itch and skin blood flow.

  2005cited by this paper
• Anandamide acts as an intracellular messenger amplifying Ca2+ influx via TRPV1 channels

  2005cited by this paper
• Changes of Epidermal Mu-Opiate Receptor Expression and Nerve Endings in Chronic Atopic Dermatitis

  2005cited by this paper
• Skin levels of vasoactive intestinal polypeptide in atopic dermatitis

  2005cited by this paper
• A hot new twist to hair biology: involvement of vanilloid receptor-1 (VR1/TRPV1) signaling in human hair growth control.

  2005cited by this paper
• Expression of IL-31 gene transcripts in NC/Nga mice with atopic dermatitis.

  2005cited by this paper
• Kappa-opioid system in uremic pruritus: multicenter, randomized, double-blind, placebo-controlled clinical studies.

  2005cited by this paper
• Cannabinoid-based drugs as anti-inflammatory therapeutics

  2005cited by this paper
• Induction of long-term cardiac allograft survival by heme oxygenase-1 gene transfer

  2004cited by this paper
• Involvement of substance P in scratching behaviour in an atopic dermatitis model.

  2004cited by this paper
• Pruritus‐associated response mediated by cutaneous histamine H3 receptors

  2004cited by this paper
• Novel aspects in cutaneous biology of acetylcholine synthesis and acetylcholine receptors

  2004cited by this paper
• Painful stimuli evoke itch in patients with chronic pruritus : Central sensitization for itch

  2004cited by this paper
• [Antipruritic therapy with the oral opioid receptor antagonist naltrexone. Open, non-placebo controlled administration in 133 patients].

  2004cited by this paper
• Involvement of histamine H4 and H1 receptors in scratching induced by histamine receptor agonists in BalbC mice

  2004cited by this paper
• Anandamide acts as a vasodilator of dural blood vessels in vivo by activating TRPV1 receptors

  2004cited by this paper
• The role of topical calcineurin inhibitors in atopic dermatitis:

  2004cited by this paper
• Painful stimuli evoke itch in patients with chronic pruritus

  2004cited by this paper
• Comparison of histamine release and prostaglandin E2 production of human basophils in atopic and normal individuals

  2004cited by this paper
• Vanilloid receptor-1 (VR1) is widely expressed on various epithelial and mesenchymal cell types of human skin.

  2004cited by this paper
• Itch and inflammation induced by intradermally injected interleukin-2 in atopic dermatitis patients and healthy subjects

  2004cited by this paper
• Vital role of the itch–scratch response in development of spontaneous dermatitis in NC/Nga mice

  2004cited by this paper
• Potentiation of histamine-induced itch and flare responses in human skin by the enkephalin analogue FK 33-824, β-endorphin and morphine

  2004cited by this paper
• Cutaneous histamine levels and histamine releasability from the skin in atopic dermatitis and hyper-IgE-syndrome

  2004cited by this paper
• Expression of vanilloid receptor subtype 1 in cutaneous sensory nerve fibers, mast cells, and epithelial cells of appendage structures

  2004cited by this paper
• Antipruritische Therapie mit dem oralen Opiatrezeptorantagonisten Naltrexon

  2004cited by this paper
• The immunosuppressant FK506 activates capsaicin- and bradykinin-sensitive DRG neurons and cutaneous C-fibers.

  2004cited by this paper
• The role of the vanilloid (capsaicin) receptor (TRPV1) in physiology and pathology.

  2004cited by this paper
• [Antipruritic effects of pimecrolimus and tacrolimus].

  2003cited by this paper
• Activation of κ-Opioid Receptors Inhibits Pruritus Evoked by Subcutaneous or Intrathecal Administration of Morphine in Monkeys

  2003cited by this paper
• Chemical response pattern of different classes of C-nociceptors to pruritogens and algogens.

  2003cited by this paper
• Neuronal sensitization for histamine-induced itch in lesional skin of patients with atopic dermatitis.

  2003cited by this paper
• TRP channels as cellular sensors

  2003cited by this paper
• Desensitization of Capsaicin-activated Currents in the Vanilloid Receptor TRPV1 Is Decreased by the Cyclic AMP-dependent Protein Kinase Pathway*

  2003cited by this paper
• Atypical expansion in mice of the sensory neuron-specific Mrg G protein-coupled receptor family

  2003cited by this paper
• Histamine induced responses are attenuated by a cannabinoid receptor agonist in human skin

  2003cited by this paper
• The Endocannabinoid System in Human Keratinocytes

  2003cited by this paper
• Itch: scratching more than the surface.

  2003cited by this paper
• Imaging of central itch modulation in the human brain using positron emission tomography

  2003cited by this paper
• Activation of Epidermal Vanilloid Receptor-1 Induces Release of Proinflammatory Mediators in Human Keratinocytes

  2003cited by this paper
• Antipruritische Wirkung von Pimecrolimus und Tacrolimus

  2003cited by this paper
• Functional vanilloid receptors in cultured normal human epidermal keratinocytes.

  2002cited by this paper
• Endovanilloid signaling in pain.

  2002cited by this paper
• Pathophysiology of pruritus in atopic dermatitis: an overview

  2002cited by this paper
• Intradermal cholinergic agonists induce itch-associated response via M3 muscarinic acetylcholine receptors in mice.

  2002cited by this paper
• Stress-induced immunomodulation is altered in patients with atopic dermatitis.

  2002cited by this paper
• Proenkephalin A gene products activate a new family of sensory neuron–specific GPCRs

  2002cited by this paper
• Bradykinin-12-lipoxygenase-VR1 signaling pathway for inflammatory hyperalgesia

  2002cited by this paper
• Experimental itch in sodium lauryl sulphate‐inflamed and normal skin in humans: a randomized, double‐blind, placebo‐controlled study of histamine and other inducers of itch

  2002cited by this paper
• Chlorpheniramine Is No More Effective than Placebo in Relieving the Symptoms of Childhood Atopic Dermatitis with a Nocturnal Itching and Scratching Component

  2002cited by this paper
• Spinothalamic lamina I neurons selectively sensitive to histamine: a central neural pathway for itch

  2001cited by this paper
• Tacrolimus ointment for the treatment of atopic dermatitis in adult patients: part I, efficacy.

  2001cited by this paper
• Treatment of prurigo nodularis with topical capsaicin.

  2001cited by this paper
• Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns(4,5)P2-mediated inhibition

  2001cited by this paper
• SDZ ASM 981: an emerging safe and effective treatment for atopic dermatitis

  2001cited by this paper
• The vanilloid receptor: a molecular gateway to the pain pathway.

  2001cited by this paper
• A diverse family of GPCRs expressed in specific subsets of nociceptive sensory neurons.

  2001cited by this paper
• Central activation by histamine‐induced itch: analogies to pain processing: a correlational analysis of O‐15 H2O positron emission tomography studies

  2001cited by this paper
• Immunoreactivity of VR1 on epidermal keratinocyte of human skin.

  2001cited by this paper
• An Experimental Itch Model in Monkeys: Characterization of Intrathecal Morphine-induced Scratching and Antinociception

  2000cited by this paper
• Buprenorphine and methoclocinnamox: agonist and antagonist effects on respiratory function in rhesus monkeys.

  2000cited by this paper
• Replenishment of RANTES mRNA expression in activated eosinophils fromatopic asthmatics

  2000cited by this paper
• Neurotrophin-4 production by human epidermal keratinocytes: increased expression in atopic dermatitis.

  2000cited by this paper
• Topische Anwendung von Capsaicin in der Dermatologie zur Therapie von Juckreiz und Schmerz

  2000cited by this paper
• Hypnosis in dermatology.

  2000cited by this paper

• Modulatory effects of bioactive natural compounds on pruritic pathways: mechanistic basis and therapeutic prospects

  2025cites this paper
• Neutrophil-derived oxidative stress contributes to skin inflammation and scratching in a mouse model of allergic contact dermatitis via triggering pro-inflammatory cytokine and pruritogen production in skin.

  2024cites this paper
• International Union of Basic and Clinical Pharmacology CXIV: Orexin Receptor Function, Nomenclature and Pharmacology

  2024cites this paper
• Pruritus and Cutaneous Lesions: Granuloma Annulare vs. Mycosis Fungoides in a Patient with Comorbidities. A Case Report

  2024cites this paper
• Vascular Endothelial Growth Factor a Promotes Chronic Itch via VEGFA-VEGFR2-PI3K-TRPV1 Axis in Allergic Contact Dermatitis

  2024cites this paper
• Cyanoacrylate Glue Reactions: A Systematic Review, Cases, and Proposed Mechanisms.

  2023cites this paper
• IL-31RA and TRPV1 Expression in Atopic Dermatitis Induced with Trinitrochlorobenzene in Nc/Nga Mice

  2023cites this paper
• Pruritus: A Sensory Symptom Generated in Cutaneous Immuno-Neuronal Crosstalk

  2022cites this paper
• Chronic Pruritus in Atopic Patients Treated with Dupilumab: Real Life Response and Related Parameters in 354 Patients

  2022cites this paper
• Atopic dermatitis: Current standards of diagnosis and treatment, including the latest methods of management

  2022cites this paper
• Neuro-immune communication regulating pruritus in atopic dermatitis.

  2022cites this paper
• Cyclosporine in Cholinergic Itch

  2022cites this paper
• Reduction of serum level of interleukin-2 and pruritus severity after acupuncture at Quchi (LI11) in hemodialysis patients: a placebo-controlled randomized clinical trial

  2022cites this paper
• Prospective, comparative clinical pilot study of cold atmospheric plasma device in the treatment of atopic dermatitis

  2021cites this paper
• Psychological Stress

  2021cites this paper
• Tolerability of and Adherence to Topical Treatments in Atopic Dermatitis: A Narrative Review

  2021cites this paper
• Genetic priming of sensory neurons in mice that overexpress PAR2 enhances allergen responsiveness

  2021cites this paper
• How Do Neurons Signal Itch?

  2021cites this paper
• Current Insights into Immunology and Novel Therapeutics of Atopic Dermatitis

  2021cites this paper
• Th2 Modulation of Transient Receptor Potential Channels: An Unmet Therapeutic Intervention for Atopic Dermatitis

  2021cites this paper
• Effects of Gammakdaejo-tang(GMD) on DNCB induced Atopic Dermatitis in Mice

  2020cites this paper
• Beneficial Effects of Adding Topical Atorvastatin 5% Cream to Topical Betamethasone 1% Ointment on Chronic Hand Eczema.

  2020cites this paper
• The Role of Nociceptive Neurons in the Pathogenesis of Psoriasis

  2020cites this paper
• Prurito: fisiopatología y enfoque diagnóstico

  2020cites this paper
• The interplay between stress and allergy

  2020cites this paper
• Pruritus – ein weiter Weg von der Neurophysiologie zur Klinik

  2020cites this paper
• [Pruritus-a long journey from neurophysiology to the clinic].

  2020cites this paper
• Role of SNAREs in Atopic Dermatitis e Related Cytokine Secretion and Skin-Nerve Communication

  2020cites this paper
• Pruritus and Atopic Dermatitis: from Etiological Features to Management

  2020cites this paper
• Effectiveness of montelukast for uremic pruritus in hemodialysis patients

  2020cites this paper
• Itching as the onset of pain (part 3)

  2020cites this paper
• Does age influence the quality of life in children with atopic dermatitis?

  2019cites this paper
• Role of SNAREs in the Atopic Dermatitis-related Cytokine Secretion and Skin-Nerve Communication.

  2019cites this paper
• Neuropathic itch

  2019cites this paper
• CCL2/CCR2 signaling elicits itch- and pain-like behavior in a murine model of allergic contact dermatitis.

  2019cites this paper
• Itch Processing in the Skin

  2019cites this paper
• Analgesic and antipruritic effects of oxymatrine sustained-release microgel cream in a mouse model of inflammatory itch and pain.

  2019cites this paper
• Tips and Tricks for Controlling Eczema.

  2019cites this paper
• Integrating tacrolimus into eutectic oil-based microemulsion for atopic dermatitis: simultaneously enhancing percutaneous delivery and treatment efficacy with relieving side effects

  2019cites this paper
• Psychoneuroimmunology and skin diseases

  2019cites this paper
• Oral H1 antihistamines as 'add-on' therapy to topical treatment for eczema.

  2019cites this paper
• Development of Organotypic Skin Disease Equivalents Mimicking Hallmarks of Atopic Dermatitis for Basic Research and Preclinical Drug Evaluation

  2018cites this paper
• Matrine inhibits itching by lowering the activity of calcium channel

  2018cites this paper
• The Turkish guideline for the diagnosis and management of atopic dermatitis-2018

  2018cites this paper
• Pruritus: Progress toward Pathogenesis and Treatment

  2018cites this paper
• Atopic Dermatitis Pertaining to Adolescents

  2018cites this paper
• Role of mast cells and basophils in pruritus

  2018cites this paper
• Atopic dermatitis

  2018cites this paper
• Itching and its related factors in subtypes of eczema: a cross-sectional multicenter study in tertiary hospitals of China

  2018cites this paper
• Chronischer Pruritus bei atopischer Dermatitis

  2018cites this paper
• British Association of Dermatologists’ guidelines for the investigation and management of generalized pruritus in adults without an underlying dermatosis, 2018

  2018cites this paper
• British Association of Dermatologists’ guidelines for the investigation and management of generalized pruritus in adults without an underlying dermatosis, 2018

  2018cites this paper
• New mechanism underlying IL‐31–induced atopic dermatitis

  2018cites this paper
• Chronischer Pruritus bei atopischer Dermatitis

  2018cites this paper
• Atopic Dermatitis: Overview

  2018cites this paper
• The Effect of Softener in Polyester Textile Fibers to the Pruritus Response and Erythema with Atopic Dermatitis Patients

  2017cites this paper
• Beneficial effects of melittin on ovalbumin-induced atopic dermatitis in mouse

  2017cites this paper
• Interleukin-31 Polymorphisms and Serum IL-31 Level in Patients with Mastocytosis: Correlation with Clinical Presen-tation and Pruritus.

  2017cites this paper
• Cl- channel is required for CXCL10-induced neuronal activation and itch response in a murine model of allergic contact dermatitis.

  2017cites this paper
• Inflammatory and Noninflammatory Itch: Implications in Pathophysiology-Directed Treatments

  2017cites this paper
• Therapeutic Effect of Montelukast for Treatment of Uremic Pruritus in Hemodialysis Patients.

  2017cites this paper
• Current insights into the role of human β‐defensins in atopic dermatitis

  2017cites this paper
• Debunking the Myth of Wool Allergy: Reviewing the Evidence for Immune and Non-immune Cutaneous Reactions.

  2017cites this paper
• Diseases with Underlining Internal Conditions

  2017cites this paper
• Modern aspects of treatment of allergic dermatitis with the secondary fungal infections

  2017cites this paper
• Oral H1 Antihistamines as 'Add-On' Therapy to Topical Treatment for Eczema

  2016cites this paper
• Bedeutung des Placeboeffektes im Vergleich zu intravenös verabreichtem H1-Antihistaminikum zur Juckreizminderung bei Patienten mit Atopischer Dermatitis

  2016cites this paper
• Immune regulation in pathophysiology and targeted therapy for itch in atopic dermatitis

  2016cites this paper
• The mediating effect of sleep satisfaction on the relationship between stress and perceived health of adolescents suffering atopic disease: Secondary analysis of data from the 2013 9th Korea Youth Risk Behavior Web-based Survey.

  2016cites this paper
• Anti‐inflammatory therapies in atopic dermatitis

  2016cites this paper
• Atopic dermatitis

  2016cites this paper
• Neue Wirkstoffe in der Pipeline zur Behandlung der atopischen Dermatitis

  2016cites this paper
• Special Therapeutic Options and Substances in the Treatment of Atopic Eczema

  2016cites this paper
• Gamisasangja-tang suppresses pruritus and atopic skin inflammation in the NC/Nga murine model of atopic dermatitis.

  2015cites this paper
• Prurido no Gato

  2015cites this paper
• Anti-Allergic Properties of Curine, a Bisbenzylisoquinoline Alkaloid

  2015cites this paper
• Ein Silberstreif am Horizont – was ist in der Pipeline an neuen Wirkstoffen bei atopischer Dermatitis?

  2015cites this paper
• The effect of Periostracum Cicadae on capsaicin-induced model of atopic dermatitis in rats

  2015cites this paper
• Use of transcutaneous electrical nerve stimulation for chronic pruritus

  2015cites this paper
• CXCR3 chemokine receptor signaling mediates itch in experimental allergic contact dermatitis

  2015cites this paper
• Ein Silberstreif am Horizont - was ist in der Pipeline an neuen Wirkstoffen bei atopischer Dermatitis?

  2015cites this paper
• Antihistamines in Atopic Dermatitis Therapy

  2015cites this paper
• Potential role of reduced environmental UV exposure as a driver of the current epidemic of atopic dermatitis.

  2015cites this paper
• Dietary deficiencies of unsaturated fatty acids and starch cause atopic dermatitis‐like pruritus in hairless mice

  2015cites this paper
• Dynamics of expression rates of growth factor proteins in psoriatic patients receiving a phototherapy

  2015cites this paper
• The relation between interleukin-31 serum levels and Staphylococcus aureus skin colonization in pediatric atopic dermatitis

  2015cites this paper
• Expression of Neuropeptides, Neurotrophins, and Neurotransmitters in the Skin of Patients with Atopic Dermatitis and Psoriasis

  2015cites this paper
• TRABALHO FINAL DO 6º ANO MÉDICO COM VISTA À ATRIBUIÇÃO DO GRAU DE MESTRE NO ÂMBITO DO CICLO DE ESTUDOS DE MESTRADO INTEGRADO EM MEDICINA

  2015influential citation
• A randomized, investigator‐blinded efficacy assessment study of stand‐alone emollient use in mild to moderately severe atopic dermatitis flares

  2014cites this paper
• Itch in atopic dermatitis: from pathogenesis to treatment

  2014cites this paper
• How to Psychologically Minimize Scratching Impulses Benefits of Placebo Effects on Itching Using Classical Conditioning and Expectancy

  2014cites this paper
• Role of PAR-2 in Neuroimmune Communication and Itch

  2014cites this paper
• Connecting the dots among the vascular actions of trypsin and thrombin , the proteolytic action of KLKs , and PARs

  2014cites this paper
• Allergen-induced production of IL-31 by canine Th2 cells and identification of immune, skin, and neuronal target cells.

  2014cites this paper
• Development of a pharmacokinetic/pharmacodynamic/disease progression model in NC/Nga mice for development of novel anti-atopic dermatitis drugs

  2014cites this paper
• Neural peptidase endothelin-converting enzyme 1 regulates endothelin 1-induced pruritus.

  2014cites this paper
• Atopic Dermatitis: Skin-Directed Management

  2014cites this paper
• Atopic Dermatitis: Skin-Directed Management abstract

  2014cites this paper
• Curine inhibits mast cell-dependent responses in mice.

  2014cites this paper
• Fisiopatología del prurito

  2014cites this paper