Phosphatidylethanol in blood (B-PEth): a marker for alcohol use and abuse.

No abstract is available for this paper.

• Publication year

  2011

• Venue

  Drug Testing and Analysis

• Publication date

  2011-04-01

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1002/dta.278PMID 21438164
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Analysis of the alcohol biomarker phosphatidylethanol by NACE with on‐line ESI‐MS

  2010cited by this paper
• Identification of 48 homologues of phosphatidylethanol in blood by LC-ESI-MS/MS

  2010cited by this paper
• CLINICAL STUDY/BIOMARKER: Phosphatidylethanol: normalization during detoxification, gender aspects and correlation with other biomarkers and self‐reports

  2010cited by this paper
• Estimating driver risk using alcohol biomarkers, interlock blood alcohol concentration tests and psychometric assessments: initial descriptives.

  2010cited by this paper
• Phosphatidylethanol and alcohol consumption in reproductive age women.

  2010cited by this paper
• Selective detection of phosphatidylethanol homologues in blood as biomarkers for alcohol consumption by LC-ESI-MS/MS.

  2009cited by this paper
• Molecular species of the alcohol biomarker phosphatidylethanol in human blood measured by LC-MS.

  2009cited by this paper
• Preliminary evaluation of phosphatidylethanol and alcohol consumption in patients with liver disease and hypertension.

  2009cited by this paper
• In vitro study of bacterial degradation of ethyl glucuronide and ethyl sulphate

  2008cited by this paper
• Kinetics in serum and urinary excretion of ethyl sulfate and ethyl glucuronide after medium dose ethanol intake

  2008cited by this paper
• Fatty acid composition of adipose tissue and blood in humans and its use as a biomarker of dietary intake.

  2008cited by this paper
• Nonaqueous capillary electrophoresis for analysis of the ethanol consumption biomarker phosphatidylethanol

  2008cited by this paper
• Immunological detection of in vitro formed phosphatidylethanol--an alcohol biomarker--with monoclonal antibodies.

  2008cited by this paper
• Detection times for urinary ethyl glucuronide and ethyl sulfate in heavy drinkers during alcohol detoxification.

  2008cited by this paper
• Comparison of ethyl glucuronide in hair with phosphatidylethanol in whole blood as post-mortem markers of alcohol abuse.

  2008cited by this paper
• Value of ethyl glucuronide in plasma as a biomarker for recent alcohol consumption in the emergency room.

  2008cited by this paper
• The usefulness of direct ethanol metabolites in assessing alcohol intake in nonintoxicated male patients in an emergency room setting.

  2008cited by this paper
• Ethylglucuronide as a Biomarker for Ethanol Detection

  2008cited by this paper
• Determination of Fatty Acid Ethyl Esters (FAEE) and Ethyl Glucuronide (EtG) in Hair: A Promising Way for Retrospective Detection of Alcohol Abuse During Pregnancy?

  2008cited by this paper
• BIOMARKER: Phosphatidylethanol as a sensitive and specific biomarker—comparison with gamma‐glutamyl transpeptidase, mean corpuscular volume and carbohydrate‐deficient transferrin

  2007cited by this paper
• Postcollection synthesis of ethyl glucuronide by bacteria in urine may cause false identification of alcohol consumption.

  2007cited by this paper
• In heavy drinkers, fatty acid ethyl esters remain elevated for up to 99 hours.

  2007cited by this paper
• PHosphatidylethanol (PEth) concentrations in blood are correlated to reported alcohol intake in alcohol-dependent patients.

  2006cited by this paper
• Ethyl sulfate: a metabolite of ethanol in humans and a potential biomarker of acute alcohol intake.

  2005cited by this paper
• Methodological modifications on quantification of phosphatidylethanol in blood from humans abusing alcohol, using high-performance liquid chromatography and evaporative light scattering detection

  2005cited by this paper
• Urinary tract infection: a risk factor for false-negative urinary ethyl glucuronide but not ethyl sulfate in the detection of recent alcohol consumption.

  2005cited by this paper
• Phosphatidylethanol formation and degradation in human and rat blood.

  2004cited by this paper
• Phosphatidylethanol in human organs and blood: a study on autopsy material and influences by storage conditions.

  2004cited by this paper
• Concentration of fatty acid ethyl esters in hair of alcoholics: comparison to other biological state markers and self reported-ethanol intake.

  2004cited by this paper
• Ethyl glucuronide discloses recent covert alcohol use not detected by standard testing in forensic psychiatric inpatients.

  2003cited by this paper
• Phosphatidylethanol in rat organs after ethanol exposure.

  2002cited by this paper
• Phosphatidylethanol in post-mortem blood as a marker of previous heavy drinking

  2001cited by this paper
• Analysis of fatty acid ethyl esters in hair as possible markers of chronically elevated alcohol consumption by headspace solid-phase microextraction (HS-SPME) and gas chromatography-mass spectrometry (GC-MS).

  2001cited by this paper
• Analysis of trimethylsilyl derivatization products of phosphatidylethanol by gas chromatography-mass spectrometry

  2000cited by this paper
• Normalization rate and cellular localization of phosphatidylethanol in whole blood from chronic alcoholics.

  2000cited by this paper
• Determination of phosphatidylethanol in blood from alcoholic males using high-performance liquid chromatography and evaporative light scattering or electrospray mass spectrometric detection.

  1998cited by this paper
• Phosphatidylethanol in blood as a marker of ethanol consumption in healthy volunteers: comparison with other markers.

  1998cited by this paper
• Blood phosphatidylethanol as a marker of alcohol abuse: levels in alcoholic males during withdrawal.

  1997cited by this paper
• Formation of phosphatidylethanol in rat brain by phospholipase D.

  1987cited by this paper
• Effects of chronic ethanol treatment on lipid composition and prostaglandins in rats fed essential fatty acid deficient diets.

  1984cited by this paper
• An abnormal phospholipid in rat organs after ethanol treatment

  1983cited by this paper

• Challenges in managing driving licence legislation when using B-Phosphatidylethanol to identify high levels of alcohol use in primary care patients: A qualitative study.

  2026cites this paper
• Decline of phosphatidylethanol (B-PEth) during abstinence in patients with alcohol use disorder undergoing withdrawal treatment, and the correlation of B-PEth with self-reported alcohol intake.

  2026cites this paper
• Alcohol Consumption Patterns up to 10 years post Bariatric Surgery: Utilizing the Highly Specific Biomarker Phosphatidylethanol (PEth)

  2026cites this paper
• Isomer Composition Assessment of Synthetic Phosphatidylethanol by Collision-Induced and Ozone-Induced Dissociation Mass Spectrometry.

  2026cites this paper
• Dysregulated hepatic alcohol metabolism: a key factor involved in the pathogenesis of alcohol-associated liver disease.

  2025cites this paper
• Calibration and Evaluation of a Refined Pharmacokinetic Model for Three Homologs of Phosphatidylethanol.

  2025cites this paper
• Unnecessary Use of Medications for Alcohol Withdrawal among Hospitalized Patients: A Retrospective Study of Phosphatidylethanol Testing in Patients with Suspected Alcohol Use Disorder.

  2025cites this paper
• RBC-GEM: A genome-scale metabolic model for systems biology of the human red blood cell

  2025cites this paper
• Quantification of Phosphatidylethanol 16:0/18:1 in blood using Supercritical Fluid Chromatography-Tandem Mass Spectrometry.

  2025cites this paper
• Phosphatidylethanol levels distinguish steatotic liver disease subgroups and are associated with risk of major liver outcomes.

  2025cites this paper
• PEth Cut‐Off Thresholds for Hazardous Alcohol Consumption Based on a Drinking Study

  2025cites this paper
• Assessment and cross-validation of calibration transferability between dried blood spot sampling devices for accurate quantification of phosphatidylethanol

  2025cites this paper
• Phosphatidylethanol levels and their association with withdrawal severity among individuals with severe alcohol use disorder seeking inpatient withdrawal management

  2025cites this paper
• Dutasteride as a Treatment to Support Reduced Drinking: A Randomized Placebo-Controlled Trial.

  2025cites this paper
• Measuring alcohol consumption with biomarkers in intervention studies: A scoping review.

  2025cites this paper
• An improved and economical LLE-LC/MS method for quantifying phosphatidylethanol: Identification and separation of isotopic cross-talk in clinical alcohol testing.

  2025cites this paper
• Low Alanine Aminotransferase Levels in Alcohol Consuming Male Subjects, Carriers of the Common ALDH2 Deficient Variant, ALDH2*2

  2025cites this paper
• Does semaglutide reduce alcohol intake in Danish patients with alcohol use disorder and comorbid obesity? Trial protocol of a randomised, double-blinded, placebo-controlled clinical trial (the SEMALCO trial)

  2025cites this paper
• A validated method for capillary phosphatidylethanol (PEth) 16:0/18:1 quantification with two different 10 µL volumetric absorptive microsample (VAMS) devices in the same set-up.

  2025cites this paper
• B-phosphatidylethanol testing to identify hazardous alcohol use in primary health care—a game changer and a challenge for general practitioners: a qualitative study

  2025cites this paper
• Phosphatidylethanol as an outcome measure in treatment aimed at controlled drinking

  2024cites this paper
• Detection of phosphatidylethanol after ethanol intake with targeted blood alcohol concentrations of 0.6 g/kg and 0.75 g/kg

  2024cites this paper
• The prevalence and correlates of biomarker positive unhealthy alcohol use among women living with and without HIV in San Francisco, California

  2024cites this paper
• Diagnosis of Alcohol Use Disorder and Alcohol-Associated Liver Disease.

  2024cites this paper
• A Brief Alcohol Intervention (BAI) to reduce alcohol use and improve PrEP outcomes among men who have sex with men in Vietnam: study protocol for a randomized controlled trial

  2024cites this paper
• Phosphatidylethanol is a promising tool for screening alcohol consumption during pregnancy.

  2024cites this paper
• Evaluation and comparison of sensitivity of alcohol biomarkers PEth, EtG and EtPa in civil cases in England 2022-2023.

  2024cites this paper
• Volumetric dried blood spots for determination of phosphatidylethanol: Validation of a liquid chromatography tandem masspectrometry method and clinical application

  2024cites this paper
• Recent alcohol intake impacts microbiota in adult burn patients.

  2024cites this paper
• A false positive hair ethylglucuronide dosage in an alcohol abstinent patient after liver transplantation: a case report

  2024cites this paper
• Phosphatidylethanol (B-PEth) and other direct and indirect biomarkers of alcohol consumption.

  2024cites this paper
• Predictive risk markers in alcoholism.

  2023cites this paper
• Alcohol use disorder in alcohol-associated liver disease: Two sides of the same coin

  2023cites this paper
• 基于智能化分时区间采集技术的液相色谱-串联质谱法测定全血中磷脂酰乙醇及人群水平调查

  2023cites this paper
• Validation of the quantification of phosphatidylethanol 16:0/18:1 concentrations in TASSO-M20 devices.

  2023cites this paper
• Moderate alcohol consumption is associated with significant fibrosis progression in NAFLD

  2023influential citation
• The alcohol biomarker phosphatidylethanol (PEth) – test performance and experiences from routine analysis and external quality assessment

  2023cites this paper
• Recognition of Nonneoplastic Hypercortisolism in the Evaluation of Patients With Cushing Syndrome

  2023cites this paper
• Development of an LC-MS/MS assay with automated sample preparation for phosphatidylethanol (PEth)- Not your typical clinical marker.

  2023cites this paper
• Brief history of the alcohol biomarkers CDT, EtG, EtS, 5-HTOL, and PEth.

  2023cites this paper
• Association of Alcohol Consumption With CD4 Recovery After Antiretroviral Therapy Initiation in St. Petersburg, Russia

  2023cites this paper
• Miniature mass spectrometer-based point-of-care assay for measuring phosphatidylethanol in blood.

  2023cites this paper
• Assessing the sensitivity and specificity of phosphatidylethanol (PEth) cutoffs to identify alcohol exposed pregnancies.

  2023cites this paper
• Protocolized screening and detection of occult alcohol use before and after liver transplant: Lessons learned from a quality improvement initiative

  2023cites this paper
• Drinking and laboratory biomarkers, and nutritional status characterize the clinical presentation of early-stage alcohol-associated liver disease.

  2023cites this paper
• Free-access intravenous alcohol self-administration in social drinkers and individuals with alcohol use disorder: Evaluation of relationships with phosphatidylethanol and self-reported alcohol consumption.

  2023cites this paper
• Alcohol-induced Cushing syndrome: report of eight cases and review of the literature

  2023cites this paper
• Assessment and Evaluation of Alcohol Use Disorder in Liver Transplant

  2023cites this paper
• Haematocrit correction of whole blood phosphatidylethanol (PEth) concentrations to estimate erythrocyte PEth concentrations: sensitivity, specificity and influence on test utility.

  2022cites this paper
• Development and validation of seven phosphatidylethanol-homologues in dried blood spots including preliminary results after excessive use of an ethanol-based hand sanitizer

  2022cites this paper
• Impact of Alcohol on Bone Health in People Living With HIV: Integrating Clinical Data From Serum Bone Markers With Morphometric Analysis in a Non‐Human Primate Model

  2022cites this paper
• False Positive Results of Phosphatidylethanol (PEth) Quantitation in Dried Blood Spots (DBS): The Influence of Alcohol Vapors

  2022cites this paper
• Utility of phosphatidylethanol testing as an objective measure of alcohol use during the preoperative evaluation for bariatric surgery.

  2022cites this paper
• Clinical Applications of State Alcohol Biomarkers: An update

  2022cites this paper
• Prevalence of and Risk Factors Associated with Alcohol Overconsumption at 2 Years After Bariatric Surgery

  2022cites this paper
• Hemorrhagic colitis induced by trientine in a 51-year-old patient with Wilson’s disease waiting for liver transplantation: A case report

  2022cites this paper
• Multi-omics Analysis of Redox Imbalance-Related Mild Health Problems in Monkeys

  2021cites this paper
• Plasma Concentrations of Lysophosphatidic Acid and Autotaxin in Abstinent Patients with Alcohol Use Disorder and Comorbid Liver Disease

  2021cites this paper
• Multi-Omics Analysis to Generate Hypotheses for Mild Health Problems in Monkeys

  2021influential citation
• Phosphatidylethanol, ethyl glucuronide and ethanol in blood as complementary biomarkers for alcohol consumption.

  2021cites this paper
• Measurement of the alcohol biomarker phosphatidylethanol (PEth) in dried blood spots and venous blood—importance of inhibition of post-sampling formation from ethanol

  2021cites this paper
• Alcohol consumption in context: The effect of psych-socio-environmental drivers

  2021cites this paper
• Multiple Tools Are Needed for the Detection of Prenatal Alcohol Exposure: Findings From a Community Antenatal Setting.

  2020cites this paper
• The roles of phosphatidylethanol (PEth), ethyl glucuronide (EtG), and ethyl sulfate (EtS) in identifying alcohol consumption among participants in professionals' health programs.

  2020cites this paper
• Performance of PEth Compared With Other Alcohol Biomarkers in Subjects Presenting For Occupational and Pre-Employment Medical Examination

  2020cites this paper
• Phosphatidylethanol Levels, As a Marker of Alcohol Consumption, Are Associated With Risk of Intracerebral Hemorrhage

  2020cites this paper
• What the lab can and cannot do: clinical interpretation of drug testing results

  2020cites this paper
• Phosphatidylethanol (PEth) reliably and objectively quantifies alcohol consumption in adolescents and young adults.

  2020cites this paper
• Blood phosphatidyl ethanol levels as a tool to detect alcohol misuse in trauma patients

  2020cites this paper
• Blood Phosphatidylethanol (PEth) Concentrations Following Regular Exposure to an Alcohol-Based Mouthwash.

  2020cites this paper
• Validating Self-Reported Unhealthy Alcohol Use With Phosphatidylethanol (PEth) Among Patients With HIV.

  2020cites this paper
• Effects of substance use on monetary delay discounting among people who use stimulants with and without HIV: An ecological momentary assessment study.

  2020cites this paper
• Comparison of the Diagnostic Value of Phosphatidylethanol and Carbohydrate-Deficient Transferrin as Biomarkers of Alcohol Consumption.

  2020cites this paper
• Biological State Marker for Alcohol Consumption

  2020cites this paper
• Moderate alcohol consumption is associated with advanced fibrosis in non-alcoholic fatty liver disease and shows a synergistic effect with type 2 diabetes mellitus.

  2020cites this paper
• Fatty acid ethyl esters in meconium: A biomarker of fetal alcohol exposure and effect

  2020cites this paper
• Neurodining: Common dietary factors may be substrates in novel biosynthetic pathways for monoaminergic neurotransmitters.

  2020cites this paper
• Reduced serum osteocalcin in high-risk alcohol using people living with HIV (PLWH) does not correlate with systemic oxidative stress or inflammation: data from the New Orleans Alcohol Use in HIV (NOAH) study.

  2019cites this paper
• Inter-Individual Variation and Factors regulating the Formation of Phosphatidylethanol (PEth).

  2019cites this paper
• Dose-Response Characteristics of the Alcohol Biomarker Phosphatidylethanol (PEth)-A Study of Outpatients in Treatment for Reduced Drinking.

  2019cites this paper
• Elimination Characteristics of the Alcohol Biomarker Phosphatidylethanol (PEth) in Blood during Alcohol Detoxification

  2019cites this paper
• Long-term stability of the alcohol consumption biomarker phosphatidylethanol in erythrocytes at -80 °C.

  2019cites this paper
• Unreported alcohol use was common but did not impact hepatitis C cure in HIV‐infected persons who use drugs

  2019cites this paper
• An automated sample preparation approach for routine liquid chromatography tandem-mass spectrometry measurement of the alcohol biomarkers phosphatidylethanol 16:0/18:1, 16:0/16:0 and 18:1/18:1.

  2019cites this paper
• Unraveling the Exposome: A Practical View

  2019cites this paper
• [Phospholipase D: its role in metabolism processes and disease development].

  2018cites this paper
• Comparison of self-reported measures of alcohol-related dependence among young Swiss men: a study protocol for a cross-sectional controlled sample

  2018cites this paper
• Providing context for phosphatidylethanol as a biomarker of alcohol consumption with a pharmacokinetic model

  2018cites this paper
• Selecting and Interpreting Alcohol Biomarker Tests: Enough to Drive You to Drink.

  2018cites this paper
• The PEth Blood Test in the Security Environment: What it is; Why it is Important; and Interpretative Guidelines

  2018cites this paper
• Phospholipase D: Its Role in Metabolic Processes and Development of Diseases

  2018cites this paper
• Alcohol Consumption in Obese Patients Before and After Gastric Bypass as Assessed with the Alcohol Marker Phosphatidylethanol (PEth)

  2018cites this paper
• Differences in the Synthesis and Elimination of Phosphatidylethanol 16: 0/18 1 and 16 0/18 2 After Acute Doses of Alcohol

  2018cites this paper
• The Food Exposome

  2018cites this paper
• High-Throughput LC-MS/MS Method for Determination of the Alcohol Use Biomarker Phosphatidylethanol in Clinical Samples by Use of a Simple Automated Extraction Procedure-Preanalytical and Analytical Conditions.

  2018cites this paper
• Study of measurement of the alcohol biomarker phosphatidylethanol (PEth) in dried blood spot (DBS) samples and application of a volumetric DBS device.

  2018cites this paper
• Determination of phosphatidylethanol 16:0/18:1 in whole blood by 96‐well supported liquid extraction and UHPLC‐MS/MS

  2018cites this paper
• Phosphatidylethanol in Comparison to Self‐Reported Alcohol Consumption Among HIV‐Infected Women in a Randomized Controlled Trial of Naltrexone for Reducing Hazardous Drinking

  2018cites this paper
• Recent alcohol use prolongs hospital length of stay following lung transplant

  2018cites this paper
• Long-term survival and predictors of relapse and survival after liver transplantation for alcoholic liver disease

  2018cites this paper