The Inner Nuclear Membrane

No abstract is available for this paper.

• Publication year

  2000

• Venue

  Journal of Membrane Biology

• Publication date

  2000-09-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1007/s002320001096PMID 10960149
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The MAN antigens are non-lamin constituents of the nuclear lamina in vertebrate cells

  2004cited by this paper
• LMNA, encoding lamin A/C, is mutated in partial lipodystrophy

  2000cited by this paper
• MAN1, an Inner Nuclear Membrane Protein That Shares the LEM Domain with Lamina-associated Polypeptide 2 and Emerin*

  2000cited by this paper
• Nuclear lamin A/C R482Q mutation in canadian kindreds with Dunnigan-type familial partial lipodystrophy.

  2000cited by this paper
• Direct interaction between emerin and lamin A.

  2000cited by this paper
• Sequential PKC- and Cdc2-mediated phosphorylation events elicit zebrafish nuclear envelope disassembly.

  1999cited by this paper
• Functional diversity of LAP2alpha and LAP2beta in postmitotic chromosome association is caused by an alpha-specific nuclear targeting domain.

  1999cited by this paper
• Loss of a-Type Lamin Expression Compromises Nuclear Envelope Integrity Leading to Muscular Dystrophy

  1999cited by this paper
• The Emery-Dreifuss muscular dystrophy phenotype arises from aberrant targeting and binding of emerin at the inner nuclear membrane.

  1999cited by this paper
• Subcellular distribution of the Xenopus p58/lamin B receptor in oocytes and eggs.

  1999cited by this paper
• Distribution of emerin during the cell cycle.

  1999cited by this paper
• Looking at lipid rafts?

  1999cited by this paper
• The tail domain of lamin Dm0 binds histones H2A and H2B.

  1999cited by this paper
• Molecular characterization and developmentally regulated expression of Xenopus lamina-associated polypeptide 2 (XLAP2).

  1999cited by this paper
• Missense mutations in the rod domain of the lamin A/C gene as causes of dilated cardiomyopathy and conduction-system disease.

  1999cited by this paper
• A role for presenilin-1 in nuclear accumulation of Ire1 fragments and induction of the mammalian unfolded protein response.

  1999cited by this paper
• Localization and phosphorylation of HP1 proteins during the cell cycle in mammalian cells

  1999cited by this paper
• LAP2 binding protein 1 (L2BP1/BAF) is a candidate mediator of LAP2-chromatin interaction.

  1999cited by this paper
• Dynamics of the nuclear lamina as monitored by GFP-tagged A-type lamins.

  1999cited by this paper
• Intracellular trafficking of emerin, the Emery-Dreifuss muscular dystrophy protein.

  1999cited by this paper
• Prenylated Prelamin A Interacts with Narf, a Novel Nuclear Protein*

  1999cited by this paper
• A Visual Screen of a Gfp-Fusion Library Identifies a New Type of Nuclear Envelope Membrane Protein

  1999cited by this paper
• Caspase-dependent proteolysis of integral and peripheral proteins of nuclear membranes and nuclear pore complex proteins during apoptosis.

  1999cited by this paper
• Mutations in the gene encoding lamin A/C cause autosomal dominant Emery-Dreifuss muscular dystrophy

  1999cited by this paper
• A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood.

  1999cited by this paper
• Roles of LAP2 Proteins in Nuclear Assembly and DNA Replication: Truncated LAP2β Proteins Alter Lamina Assembly, Envelope Formation, Nuclear Size, and DNA Replication Efficiency in Xenopus laevis Extracts

  1999cited by this paper
• Sequential recruitment of NPC proteins to the nuclear periphery at the end of mitosis.

  1999cited by this paper
• Temporal Differences in the Appearance of NEP-B78 and an LBR-like Protein during Xenopus Nuclear Envelope Reassembly Reflect the Ordered Recruitment of Functionally Discrete Vesicle Types

  1999cited by this paper
• Characterization of the Hydra Lamin and Its Gene: A Molecular Phylogeny of Metazoan Lamins

  1999cited by this paper
• LBR, a chromatin and lamin binding protein from the inner nuclear membrane, is proteolyzed at late stages of apoptosis.

  1998cited by this paper
• The human lamin B receptor/sterol reductase multigene family.

  1998cited by this paper
• The Major Nuclear Envelope Targeting Domain of LAP2 Coincides with Its Lamin Binding Region but Is Distinct from Its Chromatin Interaction Domain*

  1998cited by this paper
• Localization of the gene for familial partial lipodystrophy (Dunnigan variety) to chromosome 1q21–22

  1998cited by this paper
• Aberrant intracellular targeting and cell cycle-dependent phosphorylation of emerin contribute to the Emery-Dreifuss muscular dystrophy phenotype.

  1998cited by this paper
• Human lamin B receptor exhibits sterol C14-reductase activity in Saccharomyces cerevisiae.

  1998cited by this paper
• Caspases: enemies within.

  1998cited by this paper
• Nuclear envelope disassembly in mitotic extract requires functional nuclear pores and a nuclear lamina.

  1998cited by this paper
• Domain-specific Interactions of Human HP1-type Chromodomain Proteins and Inner Nuclear Membrane Protein LBR*

  1997cited by this paper
• GST-lamin fusion proteins act as dominant negative mutants in Xenopus egg extract and reveal the function of the lamina in DNA replication.

  1997cited by this paper
• Insertional Mutation of the Drosophila Nuclear Lamin Dm0 Gene Results in Defective Nuclear Envelopes, Clustering of Nuclear Pore Complexes, and Accumulation of Annulate Lamellae

  1997cited by this paper
• Integral Membrane Proteins of the Nuclear Envelope Are Dispersed throughout the Endoplasmic Reticulum during Mitosis

  1997cited by this paper
• Nuclear Membrane Dynamics and Reassembly in Living Cells: Targeting of an Inner Nuclear Membrane Protein in Interphase and Mitosis

  1997cited by this paper
• Heart-specific localization of emerin: new insights into Emery-Dreifuss muscular dystrophy.

  1997cited by this paper
• Domain-specific disassembly and reassembly of nuclear membranes during mitosis.

  1997cited by this paper
• Distinct Regions Specify the Targeting of Otefin to the Nucleoplasmic Side of the Nuclear Envelope*

  1997cited by this paper
• Mitotic Phosphorylation of the Lamin B Receptor by a Serine/Arginine Kinase and p34cdc2*

  1997cited by this paper
• In Vitro Assay and Characterization of the Farnesylation-dependent Prelamin A Endoprotease*

  1997cited by this paper
• Nuclear membrane vesicle targeting to chromatin in a Drosophila embryo cell-free system.

  1997cited by this paper
• Targeting of membranes to sea urchin sperm chromatin is mediated by a lamin B receptor-like integral membrane protein

  1996cited by this paper
• Interaction between an Integral Protein of the Nuclear Envelope Inner Membrane and Human Chromodomain Proteins Homologous to Drosophila HP1*

  1996cited by this paper
• The lamin B receptor (LBR) provides essential chromatin docking sites at the nuclear envelope.

  1996cited by this paper
• βII Protein Kinase C Is Required for the G2/M Phase Transition of Cell Cycle*

  1996cited by this paper
• Transforming sperm nuclei into male pronuclei in vivo and in vitro.

  1996cited by this paper
• The characterization and localization of the mouse thymopoietin/lamina-associated polypeptide 2 gene and its alternatively spliced products.

  1996cited by this paper
• Emerin deficiency at the nuclear membrane in patients with Emery-Dreif uss muscular dystrophy

  1996cited by this paper
• Cell cycle-dependent phosphorylation of nucleoporins and nuclear pore membrane protein Gp210.

  1996cited by this paper
• Chromosomal assignment of human nuclear envelope protein genes LMNA, LMNB1, and LBR by fluorescence in situ hybridization.

  1996cited by this paper
• An Alternative Splicing Product of the Lamin A/C Gene Lacks Exon 10 (*)

  1996cited by this paper
• The Emery-Dreifuss muscular dystrophy protein, emerin, is a nuclear membrane protein.

  1996cited by this paper
• Cloning of a cDNA for lamina‐associated polypeptide 2 (LAP2) and identification of regions that specify targeting to the nuclear envelope.

  1995cited by this paper
• Assembly/Disassembly of the Nuclear Envelope Membrane

  1995cited by this paper
• Signals and structural features involved in integral membrane protein targeting to the inner nuclear membrane

  1995cited by this paper
• Structural organization of the human gene (LMNB1) encoding nuclear lamin B1.

  1995cited by this paper
• A chromatin binding site in the tail domain of nuclear lamins that interacts with core histones

  1995cited by this paper
• Nuclear changes in apoptosis.

  1995cited by this paper
• cDNA Cloning and Characterization of Lamina-associated Polypeptide 1C (LAP1C), an Integral Protein of the Inner Nuclear Membrane (*)

  1995cited by this paper
• Structure and mapping of the human thymopoietin (TMPO) gene and relationship of human TMPO beta to rat lamin-associated polypeptide 2.

  1995cited by this paper
• Lamin dynamics during sea urchin male pronuclear formation in vitro.

  1995cited by this paper
• The processing pathway of prelamin A.

  1994cited by this paper
• Characterization of the human gene encoding LBR, an integral protein of the nuclear envelope inner membrane.

  1994cited by this paper
• Binding of matrix attachment regions to lamin polymers involves single-stranded regions and the minor groove

  1994cited by this paper
• Three distinct human thymopoietins are derived from alternatively spliced mRNAs.

  1994cited by this paper
• Primary structure analysis and lamin B and DNA binding of human LBR, an integral protein of the nuclear envelope inner membrane.

  1994cited by this paper
• Identification and cloning of an mRNA coding for a germ cell-specific A-type lamin in mice.

  1994cited by this paper
• Identification of a novel X-linked gene responsible for Emery-Dreifuss muscular dystrophy

  1994cited by this paper
• Stepwise reassembly of the nuclear envelope at the end of mitosis

  1993cited by this paper
• The amino-terminal domain of the lamin B receptor is a nuclear envelope targeting signal

  1993cited by this paper
• Membrane partitioning during cell division.

  1993cited by this paper
• cDNA cloning of a germ cell specific lamin B3 from mouse spermatocytes and analysis of its function by ectopic expression in somatic cells.

  1993cited by this paper
• The first membrane spanning region of the lamin B receptor is sufficient for sorting to the inner nuclear membrane

  1993cited by this paper
• The alpha‐helical rod domain of human lamins A and C contains a chromatin binding site.

  1993cited by this paper
• Integral membrane proteins of the nuclear envelope interact with lamins and chromosomes, and binding is modulated by mitotic phosphorylation.

  1993cited by this paper
• Membrane-associated lamins in Xenopus egg extracts: identification of two vesicle populations

  1993cited by this paper
• Structural organization of the human gene encoding nuclear lamin A and nuclear lamin C.

  1993cited by this paper
• Architecture and design of the nuclear pore complex.

  1992cited by this paper
• Regulation of nuclear envelope precursor functions during cell division.

  1992cited by this paper
• The lamin B receptor of the inner nuclear membrane undergoes mitosis-specific phosphorylation and is a substrate for p34cdc2-type protein kinase.

  1992cited by this paper
• The gene for a novel human lamin maps at a highly transcribed locus of chromosome 19 which replicates at the onset of S-phase

  1992cited by this paper
• Protein phosphatase type 1 in mammalian cell mitosis: chromosomal localization and involvement in mitotic exit

  1992cited by this paper
• A distinct vesicle population targets membranes and pore complexes to the nuclear envelope in Xenopus eggs

  1991cited by this paper
• Characterization of A 54-kD protein of the inner nuclear membrane: evidence for cell cycle-dependent interaction with the nuclear lamina

  1991cited by this paper
• Assembly/disassembly of the nuclear envelope membrane: cell cycle-dependent binding of nuclear membrane vesicles to chromatin in vitro.

  1991cited by this paper
• Interaction of Xenopus lamins A and LII with chromatin in vitro mediated by a sequence element in the carboxyterminal domain.

  1991cited by this paper
• Cells of the cellular immune and hemopoietic system of the mouse lack lamins A/C: distinction versus other somatic cells.

  1990cited by this paper
• Isolation and characterization of the Drosophila nuclear envelope otefin cDNA.

  1990cited by this paper
• A lamin-independent pathway for nuclear envelope assembly

  1990cited by this paper
• Isoprenylation is required for the processing of the lamin A precursor

  1990cited by this paper
• Mutation in a heterochromatin-specific chromosomal protein is associated with suppression of position-effect variegation in Drosophila melanogaster.

  1990cited by this paper
• Lamins A and C are not expressed at early stages of human lymphocyte differentiation.

  1990cited by this paper
• In vitro disassembly of the nuclear lamina and M phase-specific phosphorylation of lamins by cdc2 kinase.

  1990cited by this paper

• Hepatic management of toxic sterols after acute deletion of Cyp51 from cholesterol synthesis

  2025cites this paper
• Highly variable biological effects of statins on cancer, non-cancer, and stem cells in vitro

  2024cites this paper
• A ubiquitin-proteasome pathway degrades the inner nuclear membrane protein Bqt4 to maintain nuclear membrane homeostasis

  2023cites this paper
• Does the nuclear envelope retain its identity during mitosis?

  2022cites this paper
• STING1 in Different Organelles: Location Dictates Function

  2022cites this paper
• Chromatin epigenetics and nuclear lamina keep the nucleus in shape: Examples from natural and accelerated aging

  2022cites this paper
• Intron distribution and emerging role of alternative splicing in fungi.

  2021cites this paper
• A Unique Junctional Interface at Contact Sites Between the Endoplasmic Reticulum and Lipid Droplets

  2021influential citation
• The Torsin/ NEP1R1-CTDNEP1/ Lipin axis regulates nuclear envelope lipid metabolism for nuclear pore complex insertion

  2020cites this paper
• SUNny Ways: The Role of the SUN-Domain Protein Mps3 Bridging Yeast Nuclear Organization and Lipid Homeostasis

  2020cites this paper
• Nucleoplasmic signals promote directed transmembrane protein import simultaneously via multiple channels of nuclear pores

  2020cites this paper
• Heh2/Man1 may be an evolutionarily conserved sensor of NPC assembly state

  2020cites this paper
• Nuclear Pore Complex

  2020cites this paper
• The Cell Nucleus and Its Compartments

  2020cites this paper
• The role of very long chain fatty acids in yeast physiology and human diseases

  2020cites this paper
• Microtubule-independent movement of the fission yeast nucleus

  2020cites this paper
• Tubular ER Associates With Diacylglycerol-Rich Structures During Lipid Droplet Consumption

  2020cites this paper
• Synthesis and maintenance of lipid droplets are essential for mouse preimplantation embryonic development

  2019cites this paper
• Fluorescent Labeling of the Nuclear Envelope by Localizing Green Fluorescent Protein on the Inner Nuclear Membrane.

  2018cites this paper
• Linker of nucleoskeleton and cytoskeleton complex proteins in cardiomyopathy

  2018cites this paper
• Distinct ‘safe zones’ at the nuclear envelope ensure robust replication of heterochromatic chromosome regions

  2017cites this paper
• Nuclear Egress of Herpesviruses: The Prototypic Vesicular Nucleocytoplasmic Transport.

  2016cites this paper
• Architecture of the symmetric core of the nuclear pore

  2016cites this paper
• Expression of nuclear membrane proteins in normal, hyperplastic, and neoplastic thyroid epithelial cells

  2015cites this paper
• Linker of nucleoskeleton and cytoskeleton complex proteins in cardiac structure, function, and disease.

  2014cites this paper
• Macromolecular transport between the nucleus and the cytoplasm: Advances in mechanism and emerging links to disease.

  2014cites this paper
• Phosphorylation of connexin43 on S279/282 may contribute to laminopathy-associated conduction defects.

  2013cites this paper
• Quantitative Analysis of Membrane Protein Transport Across the Nuclear Pore Complex

  2013cites this paper
• Dynamics of Nuclear Envelope Proteins During the Cell Cycle in Mammalian Cells

  2013cites this paper
• Laminopathies: One Gene, Two Proteins, Five Diseases..

  2013cites this paper
• Genetic Therapy for Duchenne Muscular Dystrophy: Principles and Progress

  2012cites this paper
• Functional architecture of the nuclear pore complex.

  2012cites this paper
• The transport of integral membrane proteins across the nuclear pore complex

  2012cites this paper
• Nuclear Envelope Dynamics in Embryos and Somatic Cells

  2012cites this paper
• The Role of A-type Lamins in Normal Cardiac Function

  2012cites this paper
• SPAG4L, a Novel Nuclear Envelope Protein Involved in the Meiotic Stage of Spermatogenesis

  2011cites this paper
• Developing RNAi therapy For DYT1 dystonia

  2011cites this paper
• Spontaneously active ion channels of the nuclear envelope membrane

  2010cites this paper
• Redundancy and variation in the ubiquitin-mediated proteolytic targeting of a transcription factor

  2010cites this paper
• Role of novel nuclear envelope proteins involved in nuclear positioning during cell migration

  2010cites this paper
• Role of emerin and protein kinase C in herpes simplex nuclear egress

  2010cites this paper
• Emergence of a prestressed eukaryotic nucleus during cellular differentiation and development

  2010cites this paper
• A classical NLS and the SUN domain contribute to the targeting of SUN2 to the inner nuclear membrane

  2010cites this paper
• Transcriptional and proteomic profiling in a cellular model of DYT1 dystonia.

  2009cites this paper
• Reduced expression of A-type lamins and emerin activates extracellular signal-regulated kinase in cultured cells.

  2009cites this paper
• Dynamics and molecular interactions of linker of nucleoskeleton and cytoskeleton (LINC) complex proteins

  2009cites this paper
• A case of Dunnigan-type familial partial lipodystrophy (FPLD) due to lamin A/C (LMNA) mutations complicated by end-stage renal disease

  2009cites this paper
• Evaluation of Mammalian Cell-free Systems of Nuclear Disassembly and Assembly

  2008cites this paper
• Differentiation of C2C12 myoblasts expressing lamin A mutated at a site responsible for Emery-Dreifuss muscular dystrophy is improved by inhibition of the MEK-ERK pathway and stimulation of the PI3-kinase pathway.

  2008cites this paper
• Shaping the endoplasmic reticulum into the nuclear envelope

  2008cites this paper
• Structural requirements for the assembly of LINC complexes and their function in cellular mechanical stiffness.

  2008cites this paper
• Molecular genetics of the ubiquitin-proteasome system: lessons from yeast.

  2008cites this paper
• Joining the dots: production, processing and targeting of U snRNP to nuclear bodies.

  2008cites this paper
• Analysis of prelamin A biogenesis reveals the nucleus to be a CaaX processing compartment.

  2008cites this paper
• Nuclear Shape, Mechanics, and Mechanotransduction

  2008cites this paper
• Effects of heat shock on the distribution and expression levels of nuclear proteins in HeLa S3 cells

  2008cites this paper
• Sun-1, a regulator of the nuclear shape in Dictyostelium discoideum

  2007cites this paper
• Nuclear envelope protein autoantigens in primary biliary cirrhosis

  2007cites this paper
• "Laminopathies": a wide spectrum of human diseases.

  2007cites this paper
• Activation of MAPK in hearts of EMD null mice: similarities between mouse models of X-linked and autosomal dominant Emery Dreifuss muscular dystrophy.

  2007cites this paper
• Spontaneously active ion channels of membranes of the nuclear envelope of hippocampal pyramidal neurons

  2007cites this paper
• Trafficking of integral membrane proteins of the inner nuclear membrane can be mediated by the ''sorting motif'' of autographa californica nucleopolyhedrovirus odv-e66

  2006influential citation
• Spatially regulated ubiquitin ligation by an ER/nuclear membrane ligase

  2006cites this paper
• Nuclear envelope localization of human UNC84A does not require nuclear lamins

  2006cites this paper
• The localization of LAP2β during pronuclear formation in bovine oocytes after fertilization or activation

  2006cites this paper
• Inner nuclear membrane and regulation of Smad-mediated signaling.

  2006cites this paper
• The role of the nuclear envelope in cellular organization

  2006cites this paper
• Proteasome-mediated degradation of integral inner nuclear membrane protein emerin in fibroblasts lacking A-type lamins.

  2006cites this paper
• The nuclear envelope: form and reformation.

  2006cites this paper
• Characterising the expression and interactions of the endoplasmic reticulum oxidoreductase erol β

  2006cites this paper
• Role of Zmpste24 in Prelamin A Maturation.

  2005cites this paper
• Role of auto-antibodies for the diagnosis of chronic cholestatic liver diseases

  2005cites this paper
• Hepatic Steatosis in Dunnigan-Type Familial Partial Lipodystrophy

  2005cites this paper
• Dynamic properties of germ line-specific lamin B3: the role of the shortened rod domain.

  2005cites this paper
• Pushing the envelope: structure, function, and dynamics of the nuclear periphery.

  2005cites this paper
• The inner nuclear membrane protein Sun1 mediates the anchorage of Nesprin-2 to the nuclear envelope

  2005cites this paper
• Analysis of the Localization and Topology of Nurim, a Polytopic Protein Tightly Associated with the Inner Nuclear Membrane*

  2005cites this paper
• Nuclear envelope, nuclear lamina, and inherited disease.

  2005cites this paper
• Identification and biophysical characterization of a very-long-chain-fatty-acid-substituted phosphatidylinositol in yeast subcellular membranes.

  2004cites this paper
• Sun2 Is a Novel Mammalian Inner Nuclear Membrane Protein*

  2004cites this paper
• Mislocalization to the nuclear envelope: an effect of the dystonia-causing torsinA mutation.

  2004cites this paper
• Lamin-associated proteins.

  2004cites this paper
• Cotranslational integration and initial sorting at the endoplasmic reticulum translocon of proteins destined for the inner nuclear membrane.

  2004cites this paper
• Expression of a Mutant Lamin A That Causes Emery-Dreifuss Muscular Dystrophy Inhibits In Vitro Differentiation of C2C12 Myoblasts

  2004cites this paper
• Trafficking of ODV-E66 is mediated via a sorting motif and other viral proteins: facilitated trafficking to the inner nuclear membrane.

  2004cites this paper
• Antinuclear antibodies specific for primary biliary cirrhosis.

  2003cites this paper
• Nuclear envelope breakdown in starfish oocytes proceeds by partial NPC disassembly followed by a rapidly spreading fenestration of nuclear membranes

  2003cites this paper
• Effects of expressing lamin A mutant protein causing Emery-Dreifuss muscular dystrophy and familial partial lipodystrophy in HeLa cells.

  2003cites this paper
• Nuclear envelope irregularity is induced by RET/PTC during interphase.

  2003cites this paper
• Nuclear envelope alterations in fibroblasts from LGMD1B patients carrying nonsense Y259X heterozygous or homozygous mutation in lamin A/C gene.

  2003cites this paper
• XMAN 1 , an inner nuclear membrane protein , antagonizes BMP signaling by interacting with Smad 1 in Xenopus embryos

  2003influential citation
• A new clinical condition linked to a novel mutation in lamins A and C with generalized lipoatrophy, insulin-resistant diabetes, disseminated leukomelanodermic papules, liver steatosis, and cardiomyopathy.

  2003cites this paper
• Nuclear envelope proteins and neuromuscular diseases

  2003cites this paper
• Barrier-to-autointegration factor plays crucial roles in cell cycle progression and nuclear organization in Drosophila

  2003cites this paper
• The carboxyl-terminal region common to lamins A and C contains a DNA binding domain.

  2003cites this paper
• XMAN1, an inner nuclear membrane protein, antagonizes BMP signaling by interacting with Smad1 in Xenopus embryos

  2003cites this paper
• Expression of lamin A mutated in the carboxyl-terminal tail generates an aberrant nuclear phenotype similar to that observed in cells from patients with Dunnigan-type partial lipodystrophy and Emery-Dreifuss muscular dystrophy.

  2003cites this paper
• Some HIV protease inhibitors alter lamin A/C maturation and stability, SREBP-1 nuclear localization and adipocyte differentiation

  2003cites this paper
• Maladies génétiques et lamines de type A : apport de la biologie structurale

  2002cites this paper
• The Ig-like structure of the C-terminal domain of lamin A/C, mutated in muscular dystrophies, cardiomyopathy, and partial lipodystrophy.

  2002cites this paper