Regression of Electrocardiographic Left Ventricular Hypertrophy by Losartan Versus Atenolol: The Losartan Intervention For Endpoint reduction in hypertension (LIFE) Study

No abstract is available for this paper.

• Publication year

  2003

• Venue

  Circulation

• Publication date

  2003-08-12

• Fields of study

  Medicine

• Identifiers
  DOI 10.1161/01.CIR.0000083724.28630.C3PMID 12885747
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Regression of electrocardiographic left ventricular hypertrophy during antihypertensive treatment and the prediction of major cardiovascular events.

  2004cited by this paper
• Cardiovascular morbidity and mortality in patients with diabetes in the Losartan Intervention For Endpoint reduction in hypertension study (LIFE): a randomised trial against atenolol.

  2002cited by this paper
• Blood Pressure–Independent Attenuation of Cardiac Hypertrophy by AT1R-AS Gene Therapy

  2002cited by this paper
• Reduction of Cardiovascular Risk by Regression of Electrocardiographic Markers of Left Ventricular Hypertrophy by the Angiotensin-Converting Enzyme Inhibitor Ramipril

  2001cited by this paper
• Left ventricular hypertrophy and angiotensin II antagonists.

  2001cited by this paper
• The ventricular complex in left ventricular hypertrophy as obtained by unipolar precordial and limb leads. 1949.

  2001cited by this paper
• Continuous relation between left ventricular mass and cardiovascular risk in essential hypertension.

  2000cited by this paper
• Characteristics of 9194 patients with left ventricular hypertrophy: the LIFE study. Losartan Intervention For Endpoint Reduction in Hypertension.

  1998cited by this paper
• Left ventricular hypertrophy and its regression: pathophysiology and therapeutic approach: focus on treatment by antihypertensive agents.

  1998cited by this paper
• Prognostic value of a new electrocardiographic method for diagnosis of left ventricular hypertrophy in essential hypertension.

  1998cited by this paper
• Prognostic significance of serial changes in left ventricular mass in essential hypertension.

  1998cited by this paper
• The Losartan Intervention For Endpoint reduction (LIFE) in Hypertension study: rationale, design, and methods. The LIFE Study Group.

  1997cited by this paper
• Electrocardiographic identification of increased left ventricular mass by simple voltage-duration products.

  1995cited by this paper
• Improved electrocardiographic detection of echocardiographic left ventricular hypertrophy: results of a correlated data base approach.

  1995cited by this paper
• Angiotensin receptor regulates cardiac hypertrophy and transforming growth factor-beta 1 expression.

  1994cited by this paper
• Improved electrocardiographic diagnosis of left ventricular hypertrophy.

  1994cited by this paper
• Prognostic implications of baseline electrocardiographic features and their serial changes in subjects with left ventricular hypertrophy.

  1994cited by this paper
• Treatment of Mild Hypertension Study: Final Results

  1993cited by this paper
• Treatment of Mild Hypertension Study. Final results. Treatment of Mild Hypertension Study Research Group.

  1993cited by this paper
• Prognostic implications of echocardiographically determined left ventricular mass in the Framingham Heart Study.

  1990cited by this paper
• Electrocardiographic left ventricular hypertrophy and effects of antihypertensive drug therapy in hypertensive participants in the Multiple Risk Factor Intervention Trial.

  1989cited by this paper
• Five-year findings of the Hypertension Detection and Follow-up Program. Prevention and reversal of left ventricular hypertrophy with antihypertensive drug therapy. Hypertension Detection and Follow-up Program Cooperative Group.

  1985cited by this paper
• The effect of regression to the mean in epidemiologic and clinical studies.

  1976cited by this paper
• The ventricular complex in left ventricular hypertrophy as obtained by unipolar precordial and limb leads.

  1949cited by this paper
• For Personal Use. Only Reproduce with Permission from the Lancet Publishing Group

  year unknowncited by this paper

• AI-based integration of ECG biomarkers for assessing cardiac risk in type 2 diabetes mellitus with comorbid conditions for patient stratification

  2025cites this paper
• Sex-based differences in left ventricular mass reduction across angiotensin II receptor blockers in patients with heart failure with preserved or mildly reduced ejection fraction

  2024cites this paper
• The frequency of hyperuricemia with left ventricular hypertrophy in patient with primary hypertension in Erbil city-Iraq

  2023cites this paper
• Effect of Intensive Blood Pressure Control on Troponin and Natriuretic Peptide Levels: Findings From SPRINT

  2022cites this paper
• Isolated diastolic hypertension in childhood and risk of adult subclinical target organ damage: a 30-year prospective cohort study

  2022cites this paper
• A Comparative Study of Tolerability of Losartan versus Atenolol in Essential Hypertension and Their Effect on Lipid Profile

  2021cites this paper
• Comparisons of traditional electrocardiographic criteria for left and right ventricular hypertrophy in young Asian women

  2020cites this paper
• The Possibilities of Single-Pill Combinations of Antihypertensive Drugs in Cerebroprotection: Focus on the Combination of Amlodipine with Ramipril

  2020cites this paper
• Hypertension and Heart Failure: Epidemiology, Mechanisms and Treatment

  2020cites this paper
• Association between self-reported hypertension onset age and electrocardiographic left ventricular hypertrophy

  2020cites this paper
• Prognostic implications of left ventricular hypertrophy diagnosed on electrocardiogram vs echocardiography

  2020cites this paper
• Development of Electrocardiographic Left Ventricular Hypertrophy and Resting Heart Rate Over Time: Findings From the OGHMA Study

  2020cites this paper
• Body Mass Index Trajectories in Early Life Is Predictive of Cardiometabolic Risk.

  2020cites this paper
• The transition from hypertension to hypertensive heart disease and heart failure: the PREFERS Hypertension study

  2020cites this paper
• A Contemporary Approach to Hypertensive Cardiomyopathy: Reversing Left Ventricular Hypertrophy

  2020cites this paper
• Correction of QRS voltage for body mass index does not improve the prediction of fatal and nonfatal cardiovascular events. The Moli-sani study.

  2019cites this paper
• Left ventricular hypertrophy, arterial stiffness and blood pressure: exploring the Bermuda Triangle.

  2019cites this paper
• [ANMCO/SICI-GISE/SIC/SIECVI/SIRM Consensus document: Appropriateness of multimodality imaging in cardiovascular disease].

  2019cites this paper
• Cardiac and renal function interactions in heart failure with reduced ejection fraction: A mathematical modeling analysis

  2019cites this paper
• Effect of antihypertensive therapy on development of incident conduction system disease in hypertensive patients

  2019cites this paper
• Hypertension and Target Organ Damage

  2019cites this paper
• Effects of Gender and Type 2 Diabetes Mellitus on left Ventricular Structure in a Group of Hypertensive Patients in Erbil-Iraq

  2019cites this paper
• Regression Under Treatment of Left Ventricular Hypertrophy and Other Structural Alterations

  2019cites this paper
• The frequency of hyperuricemia with left ventricular hypertrophy in patient with primary hypertension in Erbil city-Iraq

  2018cites this paper
• Is Hypertension-Related Target Organ Damage Reversible/Preventable?

  2018cites this paper
• In vitro evaluation of anthracycline-induced cardiotoxicity and mitigation by perturbation of angiotensin signalling

  2018cites this paper
• New oral anticoagulants and prevention of thromboembolic events in patients with hypertension and atrial fibrillation: an appraisal

  2017cites this paper
• Prognostičko značenje hipertrofije lijeve klijetke u kardiovaskularnom kontinuumu

  2017cites this paper
• Prognostic factors of clinical endpoints in elderly patients with atrial fibrillation during a 2-year follow-up in China

  2017cites this paper
• Attitudes and preferences for the clinical management of hypertension and hypertension-related cerebrovascular disease in the general practice: results of the Italian hypertension and brain survey

  2017cites this paper
• Electrocardiographic left ventricular hypertrophy predicts atrial fibrillation independent of left ventricular mass

  2017cites this paper
• Adding markers of organ damage to risk score models improves cardiovascular risk assessment: Prospective analysis of a large cohort of adult outpatients.

  2017cites this paper
• Obesity and ECG left ventricular hypertrophy

  2017cites this paper
• Northern Shanghai Study: cardiovascular risk and its associated factors in the Chinese elderly—a study protocol of a prospective study design

  2017cites this paper
• A comparison of Cornell and Sokolow-Lyon electrocardiographic criteria for left ventricular hypertrophy in a military male population in Taiwan: the Cardiorespiratory fitness and HospItalization Events in armed Forces study.

  2017cites this paper
• Atrial Dilatation Development in Hypertensive Treated Patients: The Campania-Salute Network.

  2016cites this paper
• Patient with Essential Hypertension and Left Ventricular Hypertrophy

  2016cites this paper
• Documento ANMCO/GICR-IACPR/GISE L'organizzazione dell'assistenza nella fase post-acuta delle sindromi coronariche Commissione ANMCO/GICR-IACPR/GISE Associazione Nazionale Medici Cardiologi Ospedalieri (ANMCO) Società Italiana di Cardiologia Riabilitativa e Preventiva (GICR-IACPR) Società Italiana di

  2016cites this paper
• Blood pressure variability in controlled and uncontrolled blood pressure and its association with left ventricular hypertrophy and diastolic function

  2016cites this paper
• A dipeptidyl peptidase-4 inhibitor ameliorates hypertensive cardiac remodeling via angiotensin-II/sodium-proton pump exchanger-1 axis.

  2016cites this paper
• A call to action and a lifecourse strategy to address the global burden of raised blood pressure on current and future generations: the Lancet Commission on hypertension.

  2016cites this paper
• Association between high-sensitivity troponin T, left ventricular hypertrophy, and myocardial performance index

  2015cites this paper
• Investigations into the role of the ErbB4 receptor in cardiomyocyte hypertrophy and adult cardiac function

  2015cites this paper
• Electrocardiographic Criteria for Left Ventricular Hypertrophy in Asians Differs from Criteria Derived from Western Populations--Community-based Data from an Asian Population.

  2015cites this paper
• Pharmacotherapy of Thoracic Aortic Aneurysm

  2015cites this paper
• Left Ventricular Wall Stress–Mass–Heart Rate Product and Cardiovascular Events in Treated Hypertensive Patients: LIFE Study

  2015cites this paper
• A state of reversible compensated ventricular dysfunction precedes pathological remodelling in response to cardiomyocyte-specific activity of angiotensin II type-1 receptor in mice

  2015cites this paper
• Retinal arteriole-to-venule ratio changes and target organ disease evolution in newly diagnosed hypertensive patients at 1-year follow-up.

  2014cites this paper
• Allopurinol regresses left ventricular hypertrophy in patients with type 2 diabetes

  2014cites this paper
• Attitudes and preferences for the clinical management of hypertension and hypertension-related cardiac disease in general practice: results of the Italian Hypertension and Heart Survey

  2014cites this paper
• The effects of xanthine oxidase inhibitors on left ventricular mass and endothelial function in patients with ischaemic heart disease

  2014cites this paper
• Greater efficacy of aldosterone blockade and diuretic reinforcement vs. dual renin–angiotensin blockade for left ventricular mass regression in patients with resistant hypertension

  2014cites this paper
• Defining the natural history of uremic cardiomyopathy in chronic kidney disease: the role of cardiovascular magnetic resonance.

  2014cites this paper
• Prevention of electrocardiographic left ventricular remodeling by the angiotensin receptor blocker olmesartan in patients with type 2 diabetes

  2014cites this paper
• High–normal blood pressure is associated with new-onset electrocardiographic left ventricular hypertrophy

  2014cites this paper
• Hypertension as a Risk Factor for Heart Failure

  2014cites this paper
• Regression of electrocardiographic left ventricular hypertrophy or strain is associated with lower incidence of cardiovascular morbidity and mortality in hypertensive patients independent of blood pressure reduction - A LIFE review.

  2014cites this paper
• Angiotensin II receptor antagonists in acute coronary syndromes

  2014cites this paper
• Left Ventricular Hypertrophy: The Relationship between the Electrocardiogram and Cardiovascular Magnetic Resonance Imaging

  2014cites this paper
• Determinants Of Left Ventricular Hypertrophy Among Elderly Hypertensive In Malaysia

  2014cites this paper
• Plasma Levels of Nitric Oxide Metabolites Are Markedly Reduced in Normotensive Men With Electrocardiographically Determined Left Ventricular Hypertrophy

  2014cites this paper
• Detecting ventricular hypertrophy and atrial abnormality through the electrocardiogram.

  2014cites this paper
• Effects of antihypertensive drugs on central blood pressure: new evidence, more challenges

  2014cites this paper
• 2013 ESH/ESC guidelines for the management of arterial hypertension: the Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC).

  2013cites this paper
• 2013 ESH/ESC guidelines for the management of arterial hypertension.

  2013cites this paper
• Recommendations for the design of Phase 3 pharmaceutical trials that are more informative for patients, clinicians, and payers.

  2013cites this paper
• Diastolic blood pressure reduction contributes more to the regression of left ventricular hypertrophy: a meta-analysis of randomized controlled trials

  2013cites this paper
• The 2015 Canadian Hypertension Education Program recommendations for blood pressure measurement, diagnosis, assessment of risk, prevention, and treatment of hypertension.

  2013cites this paper
• Fixed-dose triple-combination treatments in the management of hypertension.

  2013cites this paper
• ESH / ESC Guidelines for the management of arterial hypertension

  2013cites this paper
• Strategies to improve control of blood pressure in hypertension: moving towards a 70% objective

  2013cites this paper
• Fixed-dose triple-combination treatments in the management of hypertension.

  2013cites this paper
• Medical Treatment of Hypertension in Patients with Heart Failure with Preserved Ejection Fraction

  2013cites this paper
• Impact of Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers on Mortality of Coronary Artery Bypass Grafting

  2013cites this paper
• The Transition from Hypertensive Hypertrophy to Left Ventricular Systolic Chamber Decompensation

  2013cites this paper
• Management of Stable Ischemic Heart Disease: Summary of a Clinical Practice Guideline From the American College of Physicians/American College of Cardiology Foundation/American Heart Association/American Association for Thoracic Surgery/Preventive Cardiovascular Nurses Association/Society of Thoraci

  2012cites this paper
• Renin-angiotensin antagonists: therapeutic effects beyond blood pressure control?

  2012cites this paper
• The Role of Olmesartan Medoxomil in the Management of Hypertension

  2012cites this paper
• The relationship of electrocardiographic left ventricular hypertrophy to decreased serum potassium

  2012cites this paper
• A Comparison of Cornell and Sokolow-Lyon Electrocardiographic Criteria for Left Ventricular Hypertrophy in Korean Patients

  2012cites this paper
• Why is cardiovascular risk stratification important in hypertensive patients?

  2012cites this paper
• Evaluation of Anti-Ischemic Therapy in Coronary Artery Disease: A Review

  2012cites this paper
• Losartan

  2012cites this paper
• Diagnosis of Stable Ischemic Heart Disease: Summary of a Clinical Practice Guideline From the American College of Physicians/American College of Cardiology Foundation/American Heart Association/American Association for Thoracic Surgery/Preventive Cardiovascular Nurses Association/Society of Thoracic

  2012cites this paper
• 2012 ACCF/AHA/ACP/AATS/PCNA/SCAI/STS Guideline for the diagnosis and management of patients with stable ischemic heart disease: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines, and the American College of Physicians, American Ass

  2012cites this paper
• Morphological and functional characteristics of models of experimental myocardial injury induced by isoproterenol.

  2012cites this paper
• Improving the primary prevention of cardiovascular events by using biomarkers to identify individuals with silent heart disease.

  2012cites this paper
• Precordial Bipolar Leads for Mobile ECG Applications

  2012cites this paper
• Association of Pulse Pressure With New-Onset Atrial Fibrillation in Patients With Hypertension and Left Ventricular Hypertrophy: The Losartan Intervention For Endpoint (LIFE) Reduction in Hypertension Study

  2012cites this paper
• Shooting beyond score: targeting organ disease to improve risk prediction in hypertension.

  2012influential citation
• Effects of ACE-inhibitors and angiotensin receptor blockers on inflammation.

  2012cites this paper
• Prevalence and determinants of left ventricular hypertrophy in hypertensive patients at a primary care clinic.

  2012cites this paper
• The renin-angiotensin system and right ventricular structure and function: The MESA-Right Ventricle Study

  2012cites this paper
• Evolution of target organ damage by different values of self-blood pressure measurement in untreated hypertensive patients.

  2012cites this paper
• Angiotensin Receptor Blockers: Pharmacology, Efficacy, and Safety

  2011cites this paper
• Effects of perindopril–indapamide on left ventricular diastolic function and mass in patients with type 2 diabetes: the ADVANCE Echocardiography Substudy

  2011cites this paper
• Drug Therapy for Resistant Hypertension: Simplifying the Approach

  2011cites this paper
• 8 – Retentissement de l'hypertension artérielle sur les organes cibles

  2011cites this paper
• Genetic variation in angiotensin II type 2 receptor gene influences extent of left ventricular hypertrophy in hypertrophic cardiomyopathy independent of blood pressure

  2011cites this paper
• 50 Years of Thiazides: Should Thiazide Diuretics Be Considered Third-Line Hypertension Treatment?

  2011cites this paper