The Emergence of Electron Tomography as an Important Tool for Investigating Cellular Ultrastructure

No abstract is available for this paper.

• Publication year

  2001

• Venue

  Journal of Histochemistry and Cytochemistry

• Publication date

  2001-05-01

• Fields of study

  Biology, Medicine, Materials Science

• Identifiers
  DOI 10.1177/002215540104900502PMID 11304793
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Membrane Pores

  2001influential reference
• Cryo-electron tomography of neurospora mitochondria.

  2000cited by this paper
• Electron Tomography of Frozen-Hydrated Samples

  2000cited by this paper
• Structure of the gamma-tubulin ring complex: a template for microtubule nucleation.

  2000cited by this paper
• Automated electron tomography of the septal pore cap in Rhizoctonia solani.

  2000cited by this paper
• Introduction: Our Changing Views of Mitochondria

  2000cited by this paper
• A ratchet-like inter-subunit reorganization of the ribosome during translocation

  2000cited by this paper
• The cell surface glycoprotein layer of the extreme halophile Halobacterium salinarum and its relation to Haloferax volcanii: cryo-electron tomography of freeze-substituted cells and projection studies of negatively stained envelopes.

  2000cited by this paper
• The internal structure of mitochondria.

  2000cited by this paper
• Structure of the γ-tubulin ring complex: a template for microtubule nucleation

  2000cited by this paper
• Electron crystallography of bacteriorhodopsin with millisecond time resolution.

  1999cited by this paper
• Review: electron crystallography: present excitement, a nod to the past, anticipating the future.

  1999cited by this paper
• Golgi Structure in Three Dimensions: Functional Insights from the Normal Rat Kidney Cell

  1999influential reference
• High-resolution model of the microtubule.

  1999cited by this paper
• Situs: A package for docking crystal structures into low-resolution maps from electron microscopy.

  1999cited by this paper
• Cubic membrane structure in amoeba (Chaos carolinensis) mitochondria determined by electron microscopic tomography.

  1999cited by this paper
• Averaging data derived from images of helical structures with different symmetries.

  1999cited by this paper
• Tomographic 3D reconstruction of quick-frozen, Ca2+-activated contracting insect flight muscle.

  1999influential reference
• Electron tomography of molecules and cells.

  1999cited by this paper
• Three-dimensional transmission electron microscopy and its application to mitosis research.

  1999cited by this paper
• High-voltage electron tomography of spindle pole bodies and early mitotic spindles in the yeast Saccharomyces cerevisiae.

  1999cited by this paper
• The Tom Core Complex

  1999cited by this paper
• Modification of Postsynaptic Densities after Transient Cerebral Ischemia: A Quantitative and Three-Dimensional Ultrastructural Study

  1999cited by this paper
• Multivariate statistical analysis of three-dimensional cross-bridge motifs in insect flight muscle

  1999cited by this paper
• Electron tomography of ice-embedded prokaryotic cells.

  1998cited by this paper
• A new look at kinetochore structure in vertebrate somatic cells using high-pressure freezing and freeze substitution

  1998cited by this paper
• Structure of the alpha beta tubulin dimer by electron crystallography.

  1998cited by this paper
• Three-dimensional transmission electron microscopy and its application to mitosis research.

  1998cited by this paper
• High-Resolution Model of the Microtubule We recently obtained the structure of the tubulin dimer

  1998cited by this paper
• Group II chaperonin in an open conformation examined by electron tomography

  1998cited by this paper
• Electron microscopy of frozen biological objects: a study using cryosectioning and cryosubstitution

  1998cited by this paper
• The disassembly and reassembly of functional centrosomes in vitro.

  1998cited by this paper
• Macromolecular structure determination by electron microscopy: new advances and recent results.

  1998cited by this paper
• Electron tomography of metaphase nucleolar organizer regions: evidence for a twisted-loop organization.

  1997cited by this paper
• Approaches for High Resolution Cryo-Electron Tomography of Biological Specimens

  1997cited by this paper
• Electron microscopic tomography: A tool for probing the structure and function of subcellular components

  1997cited by this paper
• Electron tomography of neuronal mitochondria: three-dimensional structure and organization of cristae and membrane contacts.

  1997cited by this paper
• The Golgi Apparatus

  1997influential reference
• Practical image restoration of thick biological specimens using multiple focus levels in transmission electron microscopy.

  1997cited by this paper
• Dual-axis tomography: an approach with alignment methods that preserve resolution.

  1997influential reference
• Perspectives of molecular and cellular electron tomography.

  1997cited by this paper
• Reconsidering mitochondrial structure: new views of an old organelle.

  1997influential reference
• Electron tomography of large, multicomponent biological structures.

  1997cited by this paper
• The yeast spindle pole body is assembled around a central crystal of Spc42p.

  1997cited by this paper
• Super-Thin Serial Sectioning for High-Resolution 3-D Reconstruction of Cellular Structures

  1997cited by this paper
• Low-dose automated electron tomography: a recent implementation.

  1997cited by this paper
• Three-dimensional image reconstruction of large nuclear RNP (lnRNP) particles by automated electron tomography.

  1997cited by this paper
• Kinetochore Fiber Maturation in PtK1 Cells and Its Implications for the Mechanisms of Chromosome Congression and Anaphase Onset

  1997cited by this paper
• Sterecon--three-dimensional reconstructions from stereoscopic contouring.

  1996cited by this paper
• Computer visualization of three-dimensional image data using IMOD.

  1996cited by this paper
• Low resolution meets high: towards a resolution continuum from cells to atoms.

  1996cited by this paper
• Toward fully automated high-resolution electron tomography.

  1996cited by this paper
• The relevance of dose-fractionation in tomography of radiation-sensitive specimens.

  1995cited by this paper
• Double-tilt electron tomography.

  1995influential reference
• Nucleation of microtubule assembly by a γ-tubulin-containing ring complex

  1995cited by this paper
• Microtubule nucleation by γ-tubulin-containing rings in the centrosome

  1995cited by this paper
• Em‐tomography of section collapse, a non‐linear phenomenon

  1995cited by this paper
• Chromatin organization re-viewed.

  1995cited by this paper
• Microtubule nucleation by gamma-tubulin-containing rings in the centrosome.

  1995cited by this paper
• Nucleation of microtubule assembly by a gamma-tubulin-containing ring complex.

  1995cited by this paper
• Serial section electron tomography: a method for three-dimensional reconstruction of large structures.

  1994cited by this paper
• HVEM tomography of the trans-Golgi network: structural insights and identification of a lace-like vesicle coat

  1994cited by this paper
• Electron microscopy and EM immunocytochemistry.

  1994cited by this paper
• Restoration of high-tilt electron micrographs using a focus series.

  1994cited by this paper
• Structure of the actin-myosin complex and its implications for muscle contraction.

  1993cited by this paper
• Mineral and organic matrix interaction in normally calcifying tendon visualized in three dimensions by high-voltage electron microscopic tomography and graphic image reconstruction.

  1993cited by this paper
• Kinetochore microtubules in PTK cells

  1992cited by this paper
• Sample Shrinkage and Radiation Damage

  1992cited by this paper
• Least-Squares Method of Alignment Using Markers

  1992cited by this paper
• Measurement of neuronal surface area using high-voltage electron microscope tomography.

  1992cited by this paper
• 280 Nucleolar organizer region (NOR) 銀染色を用いたサルコイドーシス患者における BALF細胞の検討

  1991cited by this paper
• The nucleolar organizer regions

  1990cited by this paper
• γ-tubulin is a component of the spindle pole body that is essential for microtubule function in Aspergillus nidulans

  1990cited by this paper
• Three‐dimensional electron microscopy of entire cells

  1990cited by this paper
• Computer image processing of electron micrographs of biological structures with helical symmetry.

  1988cited by this paper
• Cryo-electron microscopy of vitrified specimens

  1988cited by this paper
• Three-dimensional tomographic reconstruction in high voltage electron microscopy

  1987cited by this paper
• Three-Dimensional Reconstruction of Nonperiodic Macromolecular Assemblies from Electron Micrographs

  1986cited by this paper
• Thick and thin serial sectioning for the three-dimensional reconstruction of biological ultrastructure.

  1981cited by this paper
• Decrease in section thickness on exposure to the electron beam; the use of tilted sections in estimating the amount of shrinkage.

  1974cited by this paper
• The reconstruction of a three-dimensional structure from projections and its application to electron microscopy

  1970cited by this paper
• Ultrastructure of retinal rod synapses of the guinea pig eye as revealed by three-dimensional reconstructions from serial sections.

  1958cited by this paper

• Research on the SEGDC‐UNet electron microscope image segmentation algorithm based on channel attention mechanism

  2025cites this paper
• ETSpy: A HyperSpy extension package for electron tomography data processing and reconstruction.

  2024cites this paper
• The application and development of electron microscopy for three-dimensional reconstruction in life science: a review

  2024cites this paper
• Electron Tomography as a Tool to Study SARS-CoV-2 Morphology

  2024cites this paper
• Electron tomography unravels new insights into fiber cell wall nanostructure; exploring 3D macromolecular biopolymeric nano-architecture of spruce fiber secondary walls

  2023cites this paper
• Correlative light and volume electron microscopy to study brain development.

  2023cites this paper
• New revelations on the interplay between cardiomyocyte architecture and cardiomyocyte function in growth, health, and disease: a brief introduction

  2022cites this paper
• Electron microscopy for imaging organelles in plants and algae.

  2021cites this paper
• Local quantification of mesoporous silica microspheres using multiscale electron tomography and lattice Boltzmann simulations

  2020cites this paper
• Characterization of Metal‐zeolite Composite Catalysts: Determining the Environment of the Active Phase

  2020cites this paper
• Electron tomography and immunogold labeling of plant cells.

  2020cites this paper
• Imaging Plant Cells by High-Pressure Freezing and Serial block-face scanning electron microscopy.

  2020cites this paper
• Three-dimensional single-molecule tracking in living cells

  2019cites this paper
• Application of iterative reconstruction algorithms to mitigate CT-artefacts when measuring fiber reinforced polymer materials

  2019cites this paper
• Endoplasmic reticulum remodeling induced by Wheat yellow mosaic virus infection studied by transmission electron microscopy.

  2019cites this paper
• X-ray tomography shows the varying three-dimensional morphology of gold nanoaggregates in the cellular ultrastructure

  2019cites this paper
• Soft X-ray tomography: virtual sculptures from cell cultures.

  2019cites this paper
• Segmentation of Features in Electron Tomographic Reconstructions

  2018cites this paper
• Electron tomography in plant cell biology.

  2018cites this paper
• Electron Microscopic Analysis of the Plasma Membrane and Cell Surface Molecules

  2018cites this paper
• Optical Imaging: How Far Can We Go

  2017cites this paper
• Structure and components of the globular and filamentous viroplasms induced by Rice black-streaked dwarf virus.

  2017cites this paper
• Assumption-free morphological quantification of single anisotropic nanoparticles and aggregates.

  2017cites this paper
• Mapping brain structure and function: cellular resolution, global perspective

  2017cites this paper
• Correlative Super-Resolution Microscopy: New Dimensions and New Opportunities.

  2017cites this paper
• Data to the dissertation "A study on the CO₂ fixation pathway of Ignicoccus hospitalis"

  2016cites this paper
• Electron tomography analysis of 3D order and interfacial structure in nano-precipitates

  2016cites this paper
• Mutual association of Broad bean wilt virus 2 VP37-derived tubules and plasmodesmata obtained from cytological observation

  2016cites this paper
• Gradient Projection for Regularized Cryo-Electron Tomographic Reconstruction

  2015cites this paper
• Developing 3D SEM in a broad biological context

  2015cites this paper
• Analysis of primary cilia in the developing mouse brain.

  2015cites this paper
• Efficient Extraction of Macromolecular Complexes from Electron Tomograms Based on Reduced Representation Templates

  2015cites this paper
• Dynamical Aspects of Biomacromolecular Multi-resolution Modelling Using the UltraScan Solution Modeler (US-SOMO) Suite

  2014cites this paper
• Visualizing compaction of polysomes in bacteria.

  2014cites this paper
• Tumours induced by a plant virus are derived from vascular tissue and have multiple intercellular gateways that facilitate virus movement.

  2014cites this paper
• A high-resolution morphological and ultrastructural map of anterior sensory cilia and glia in Caenorhabditis elegans

  2014cites this paper
• The segmentation of microtubules in electron tomograms using Amira.

  2014cites this paper
• Electron tomography of dislocation structures

  2014cites this paper
• Exploring the third dimension: volume electron microscopy comes of age.

  2014cites this paper
• Mitosis

  2014cites this paper
• Compensation of Missing Wedge Effects with Sequential Statistical Reconstruction in Electron Tomography

  2014influential citation
• Structural organization of the polysomes adjacent to mammalian processing bodies (P-bodies)

  2013cites this paper
• Towards an integrated materials characterization toolbox

  2013cites this paper
• Towards an integrated materials characterization toolbox

  2013cites this paper
• Fibrinogen species as resolved by HPLC-SAXS data processing within the UltraScan Solution Modeler (US-SOMO) enhanced SAS module

  2013cites this paper
• Electron Microscopy Reconstruction of Brain Structure Using Sparse Representations Over Learned Dictionaries

  2013cites this paper
• Inelastic Scattering in STEM for Studying Structural and Electronic Properties of Chalcogenide-Based Semiconductor Nanocrystals

  2013cites this paper
• Replicación y ensamblaje del Arbovirus Bunyamwera en células del insecto vector Aedes albopictus

  2013cites this paper
• D-CAT: Density and Clustering Annotation Tool for three dimensional electron microscopic volumes.

  2012cites this paper
• 3-DIMENSIONAL ELECTRON MICROSCOPY OF BIOLOGICAL SPECIMENS by Korrinn

  2012influential citation
• 3-Dimensional Electron Microscopy of Biological Specimens

  2012cites this paper
• Three-dimensional visualization of forming Hepatitis C virus-like particles by electron-tomography.

  2012cites this paper
• Electron Tomography of HEK293T Cells Using Scanning Electron Microscope–Based Scanning Transmission Electron Microscopy

  2012cites this paper
• Transmission Electron Microscopy: A Multifunctional Tool for the Atomic-scale Characterization of Nanoalloys

  2012cites this paper
• A Novel Approach for Intracellular 3D Immuno‐Labeling for Electron Tomography

  2012cites this paper
• Surface segregation in TiO2-based nanocomposite thin films

  2012cites this paper
• Thinning of large mammalian cells for cryo‐TEM characterization by cryo‐FIB milling

  2012cites this paper
• Immuno EM-OM correlative microscopy in solution by atmospheric scanning electron microscopy (ASEM).

  2012cites this paper
• Dynamic Load Scheduling on CPU-GPU for Iterative Tomographic Reconstruction

  2012cites this paper
• 3D structure determination of native mammalian cells using cryo-FIB and cryo-electron tomography.

  2012cites this paper
• Automated Analysis of Biomedical Data from Low to High Resolution

  2012cites this paper
• Super-resolution using Sparse Representations over Learned Dictionaries: Reconstruction of Brain Structure using Electron Microscopy

  2012influential citation
• Toward A 3D View of Cellular Architecture: Correlative Light Microscopy and Electron Tomography

  2012cites this paper
• New Insights into HTLV-1 Particle Structure, Assembly, and Gag-Gag Interactions in Living Cells

  2011cites this paper
• High resolution 3D perspective of Plasmodium biology: advancing into a new era.

  2011cites this paper
• Determination of Bulk and Solution Morphologies by Transmission Electron Microscopy

  2011cites this paper
• Towards an integrated materials characterization toolbox

  2011cites this paper
• An ultrastructural study of the role of clathrin as an inter-microtubule bridge in kinetochore fibres

  2011cites this paper
• Mapping the β-Cell in 3D at the Nanoscale Using Novel Cellular Electron Tomography and Computational Approaches

  2011cites this paper
• The Organisation of Replisomes

  2011cites this paper
• High Resolution Segmentation of Neuronal Tissues from Low Depth-Resolution EM Imagery

  2011cites this paper
• Three-dimensional visualization of dislocation-precipitate interactions in a Al–4Mg–0.3Sc alloy using weak-beam dark-field electron tomography

  2011cites this paper
• ELUCIDATING STRUCTURE-FUNCTION RELATIONSHIPS FROM MOLECULE-TO-CELL-TO-TISSUE : FROM RESEARCH MODALITIES TO CLINICAL REALITIES

  2010cites this paper
• Methods for segmentation and interpretation of electron tomographic reconstructions.

  2010cites this paper
• Telocytes in pleura: two- and three-dimensional imaging by transmission electron microscopy

  2010cites this paper
• Out of Many, One: Modeling Schemes for Biopolymer and Biofibril Networks

  2010cites this paper
• Spiral Coating of the Endothelial Caveolar Membranes as Revealed by Electron Tomography and Template Matching

  2010cites this paper
• Chapter 5 – Microscopy

  2010cites this paper
• Increasing depth resolution of electron microscopy of neural circuits using sparse tomographic reconstruction

  2010cites this paper
• Bright-field electron tomography of individual inorganic fullerene-like structures.

  2010cites this paper
• Structural Evidence of Glycoprotein Assembly in Cellular Membrane Compartments prior to Alphavirus Budding

  2010cites this paper
• 3D reconstruction of Chlamydomonas flagellar outer dynein arm in the presence of nucleotides

  2010cites this paper
• Monte Carlo electron-trajectory simulations in bright-field and dark-field STEM: implications for tomography of thick biological sections.

  2009cites this paper
• Towards correlative imaging of plant cortical microtubule arrays: combining ultrastructure with real‐time microtubule dynamics

  2009cites this paper
• Organization of human replicon: Singles or zipping couples?

  2009cites this paper
• Exploring photosynthesis by electron tomography

  2009cites this paper
• Tomography of the cell nucleus using confocal microscopy and medium voltage electron microscopy.

  2009cites this paper
• Technical note: a tool for determining rotational tilt axis with or without fiducial markers.

  2009cites this paper
• Nanoscale 3D cellular imaging by axial scanning transmission electron tomography

  2009cites this paper
• Tannic acid-mediated osmium impregnation after freeze-substitution: a strategy to enhance membrane contrast for electron tomography.

  2009cites this paper
• Analysing the lattice transition of thin filaments in striated muscle

  2009cites this paper
• Elucidating structure-function relationships from molecule-to-cell-to-tissue: from research modalities to clinical realities.

  2009cites this paper
• Analysis of 3D elemental mapping artefacts in biological specimens using Monte Carlo simulation

  2009cites this paper
• Electron tomography of microtubule end-morphologies in C. elegans embryos.

  2009cites this paper
• Three-dimensional nanoscale imaging of polymer bulk-heterojunction by scanning electrical potential microscopy and C60(+) cluster ion slicing.

  2009cites this paper
• Caracterización estructural de los complejos replicativos en factorías de virus RNA

  2009cites this paper
• Architecture of Thylakoid Membrane Networks

  2009cites this paper
• Electron microscopy of the early Caenorhabditis elegans embryo

  2008cites this paper
• Electron tomography: a short overview with an emphasis on the absorption potential model for the forward problem

  2008cites this paper
• Three-Dimensional Electron Microscopy. A Gateway to Photosynthetic Structure

  2008cites this paper