Age-related macular changes in humans over 90 years old.

No abstract is available for this paper.

• Publication year

  1990

• Venue

  American journal of ophthalmology-glaucoma

• Publication date

  1990-03-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/S0002-9394(14)74549-0PMID 2309857
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  1989cited by this paper
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  1986cited by this paper
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  1986cited by this paper
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  1984cited by this paper
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  1982cited by this paper
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  1981cited by this paper
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  1980cited by this paper
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  1980cited by this paper
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  1979cited by this paper
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  1978cited by this paper
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  1976cited by this paper
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  1969cited by this paper
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  1968cited by this paper
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  1968cited by this paper
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  1951cited by this paper

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