Inhibition of trans-plasma membrane electron transport: a potential anti-leukemic strategy.

No abstract is available for this paper.

• Publication year

  2010

• Venue

  Leukemia research : a Forum for Studies on Leukemia and Normal Hemopoiesis

• Publication date

  2010-12-01

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1016/j.leukres.2010.02.032PMID 20334912
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The anti-cancer drug, phenoxodiol, kills primary myeloid and lymphoid leukemic blasts and rapidly proliferating T cells

  2009cited by this paper
• Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

  2009influential reference
• Antitumor activity of bis-indole derivatives.

  2008cited by this paper
• Cell surface oxygen consumption: a major contributor to cellular oxygen consumption in glycolytic cancer cell lines.

  2007cited by this paper
• Why is cancer drug discovery so difficult?

  2007cited by this paper
• Plasma membrane electron transport: a new target for cancer drug development.

  2006cited by this paper
• Tetrazolium dyes as tools in cell biology: new insights into their cellular reduction.

  2005cited by this paper
• Designed multiple ligands. An emerging drug discovery paradigm.

  2005cited by this paper
• Potential antitumor agents. 37. Synthesis and antitumor activity of guanylhydrazones from imidazo[2,1-b]thiazoles and from the new heterocyclic system thiazolo[2',3':2,3]imidazo[4,5-c]quinoline.

  2005cited by this paper
• Mitochondrial gene-knockout (rho0) cells: a versatile model for exploring the secrets of trans-plasma membrane electron transport.

  2004cited by this paper
• Akt Stimulates Aerobic Glycolysis in Cancer Cells

  2004cited by this paper
• Contribution of reactive oxygen species to the regulation of Glut1 in two hemopoietic cell lines differing in cytokine sensitivity.

  2004cited by this paper
• Mitochondrial gene‐knockout (ρ0) cells: A versatile model for exploring the secrets of trans‐plasma membrane electron transport

  2004cited by this paper
• Rapid chemosensitivity testing of human lung tumor cells using the MTT assay

  2004cited by this paper
• Distinct trans-plasma membrane redox pathways reduce cell-impermeable dyes in HeLa cells

  2004cited by this paper
• Substituted E-3-(2-Chloro-3-indolylmethylene)1,3-dihydroindol-2-ones with antitumor activity.

  2004cited by this paper
• Redox regulation of ascorbic acid transport: Role of transporter and intracellular sulfhydryls

  2004cited by this paper
• Contributions of cell metabolism and H+ diffusion to the acidic pH of tumors.

  2003cited by this paper
• Overexpression of Glut‐1 and increased glucose metabolism in tumors are associated with a poor prognosis in patients with oral squamous cell carcinoma

  2003cited by this paper
• Low mitochondrial respiratory chain content correlates with tumor aggressiveness in renal cell carcinoma.

  2002cited by this paper
• Monitoring NAD(P)H autofluorescence to assess mitochondrial metabolic functions in rat hippocampal-entorhinal cortex slices.

  2001cited by this paper
• Synthesis and antitumor activity of substituted 3-(5-imidazo[2,1-b]thiazolylmethylene)-2-indolinones.

  2001cited by this paper
• Acute regulation of glucose transport in a human megakaryocytic cell line: difference between growth factors and H(2)O(2).

  2001cited by this paper
• Plasma Membrane Redox System in the Control of Stress-Induced Apoptosis

  2000cited by this paper
• Ascorbate stabilization is stimulated in rho(0)HL-60 cells by CoQ10 increase at the plasma membrane.

  1997cited by this paper
• Aerobic Glycolysis by Proliferating Cells: Protection against Oxidative Stress at the Expense of Energy Yield

  1997influential reference
• An erythroid and megakaryocytic common precursor cell line (B1647) expressing both c‐mpl and erythropoietin receptor (Epo‐R) proliferates and modifies globin chain synthesis in response to megakaryocyte growth and development factor (MGDF) but not to erythropoietin (Epo)

  1997cited by this paper
• Ascorbate Stabilization Is Stimulated in ρ°HL-60 Cells by CoQ10Increase at the Plasma Membrane☆

  1997cited by this paper
• Isolation of human cell lines lacking mitochondrial DNA.

  1996cited by this paper
• Up-regulation of the plasma membrane oxidoreductase as a prerequisite for the viability of human Namalwa rho 0 cells.

  1994cited by this paper
• The concept of multifactorial etiology of cancer.

  1993cited by this paper
• HEL cells: a new human erythroleukemia cell line with spontaneous and induced globin expression.

  1982cited by this paper
• Tumor mitochondria and the bioenergetics of cancer cells.

  1978cited by this paper

• Cellular reductive stress: Is plasma membrane electron transport an evolutionarily-conserved safety valve?

  2023cites this paper
• The effect of hyperbaric oxygen on mitochondrial and glycolytic energy metabolism: the caloristasis concept

  2020cites this paper
• Mechanistic insight into heterogeneity of trans-plasma membrane electron transport in cancer cell types.

  2019cites this paper
• Fructose Intake, Serum Uric Acid, and Cardiometabolic Disorders: A Critical Review

  2017cites this paper
• Ruthenium‐Based Anticancer Compounds: Insights into Their Cellular Targeting and Mechanism of Action

  2017cites this paper
• Identification of Arsenic Direct-Binding Proteins in Acute Promyelocytic Leukaemia Cells

  2015cites this paper
• Enhancement of mitochondrial ATP production by the Escherichia coli cytotoxic necrotizing factor 1

  2014cites this paper
• Anticancer activity of structurally related ruthenium(II) cyclopentadienyl complexes

  2014cites this paper
• Cell hierarchy, metabolic flexibility and systems approaches to cancer treatment.

  2013cites this paper
• In Vivo Inhibition of Trans-Plasma Membrane Electron Transport by Antiviral Drugs in Grapevine

  2013influential citation
• Tumor regression with a combination of drugs interfering with the tumor metabolism: efficacy of hydroxycitrate, lipoic acid and capsaicin

  2013cites this paper
• Anti-leukemic activity of ubiquinone-based compounds targeting trans-plasma membrane electron transport.

  2013cites this paper
• Phytochemical Profile and Nutraceutical Value of Old and Modern Common Wheat Cultivars

  2012cites this paper
• Trans-Plasma Membrane Electron Transport in Mammals: Functional Significance in Health and Disease

  2011cites this paper