Tumor mitochondria and the bioenergetics of cancer cells.

No abstract is available for this paper.

• Publication year

  1978

• Venue

  Progress in experimental tumor research

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1159/000401202PMID 149996
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• No references are available for this paper.

• Targeting the epigenome and tumor heterogeneity: advances in immunotherapy for chemoresistant metastatic colorectal cancer

  2025cites this paper
• The Warburg hypothesis and the emergence of the mitochondrial metabolic theory of cancer

  2025cites this paper
• Mitochondrial–Stem Cell Connection: Providing Additional Explanations for Understanding Cancer

  2024cites this paper
• Regulation of mitochondrial oxidative phosphorylation through tight control of cytochrome c oxidase in health and disease – Implications for ischemia/reperfusion injury, inflammatory diseases, diabetes, and cancer

  2024cites this paper
• BAMBI Is a Prognostic Biomarker Associated with Macrophage Polarization, Glycolysis, and Lipid Metabolism in Hepatocellular Carcinoma

  2024cites this paper
• The Warburg Effect: Is it Always an Enemy?

  2024cites this paper
• Targeting Mitochondria for Cancer Treatment

  2024cites this paper
• Mechanism and rational combinations with GP‐2250, a novel oxathiazine derivative, in ovarian cancer

  2024cites this paper
• Modulating Glycolysis to Improve Cancer Therapy

  2023cites this paper
• ANT2 accelerates cutaneous wound healing in aged skin via regulating energy homeostasis and inflammation.

  2023cites this paper
• The Mitochondrial ATP Synthase/IF1 Axis in Cancer Progression: Targets for Therapeutic Intervention

  2023cites this paper
• Metabolic factors associated with the prognosis of oligometastatic patients treated with stereotactic body radiotherapy

  2023cites this paper
• Deficiência aguda de tiamina: Efeitos no crescimento e resposta quimioterápica de um fibro-histiocitoma maligno de rato

  2023cites this paper
• The Interplay between Dysregulated Metabolism and Epigenetics in Cancer

  2023cites this paper
• Compound C Inhibits Ovarian Cancer Progression via PI3K-AKT-mTOR-NFκB Pathway

  2022cites this paper
• Cancer depends on fatty acids for ATP production: a possible link between cancer and obesity.

  2022cites this paper
• Tackling the Behavior of Cancer Cells: Molecular Bases for Repurposing Antipsychotic Drugs in the Treatment of Glioblastoma

  2022cites this paper
• Historical perspective of tumor glycolysis: a century with Otto Warburg.

  2022cites this paper
• Upregulation of Succinate Dehydrogenase (SDHA) Contributes to Enhanced Bioenergetics of Ovarian Cancer Cells and Higher Sensitivity to Anti-Metabolic Agent Shikonin

  2022cites this paper
• Cell line-directed breast cancer research based on glucose metabolism status.

  2021cites this paper
• Mitochondria and Tumor Metabolic Flexibility: Mechanisms and Therapeutic Perspectives

  2021cites this paper
• A pan-cancer transcriptomic study showing tumor specific alterations in central metabolism

  2021cites this paper
• Pyruvate kinase M2 in chronic inflammations: a potpourri of crucial protein–protein interactions

  2021cites this paper
• α-Lipoic Acid Targeting PDK1/NRF2 Axis Contributes to the Apoptosis Effect of Lung Cancer Cells

  2021cites this paper
• Mitochondria and Its Permeability Transition Pore in Cancer Metabolic Reprogramming.

  2021cites this paper
• Mitochondrial DNA variation and cancer

  2021cites this paper
• Overall survival of pancreatic ductal adenocarcinoma is doubled by Aldh7a1 deletion in the KPC mouse

  2021cites this paper
• Mitochondrial Inhibition: a Treatment Strategy in Cancer?

  2021cites this paper
• Plasmalogen Deficiency and Overactive Fatty Acid Elongation Biomarkers in Serum of Breast Cancer Patients Pre- and Post-Surgery—New Insights on Diagnosis, Risk Assessment, and Disease Mechanisms

  2021cites this paper
• Group of Uniform Materials Based on Organic Salts (GUMBOS): A Review of Their Solid State Properties and Applications

  2021cites this paper
• Mitochondria as playmakers of apoptosis, autophagy and senescence.

  2020cites this paper
• The Invisible Rainbow: A History of Electricity and Life

  2020cites this paper
• Mitochondrial changes in carcinogenesis as a goal of antitumor therapy (review)

  2020cites this paper
• ATP Production Relies on Fatty Acid Oxidation Rather than Glycolysis in Pancreatic Ductal Adenocarcinoma

  2020cites this paper
• Physiological and Pathophysiological Roles of Ion Transporter-Mediated Metabolism in the Thyroid Gland and in Thyroid Cancer

  2020cites this paper
• Role of Mitochondrial Glycerol-3-Phosphate Dehydrogenase in Metabolic Adaptations of Prostate Cancer

  2020cites this paper
• On the Origin of ATP Synthesis in Cancer

  2020cites this paper
• Age-associated mitochondrial DNA mutations cause metabolic remodeling that contributes to accelerated intestinal tumorigenesis

  2020cites this paper
• Impact of mitochondrial transcription factor A expression on the outcomes of ovarian, endometrial and cervical cancers.

  2020cites this paper
• Physiological and Pathophysiological Roles of Ion Transporter-Mediated Metabolism in the Thyroid Gland and in Thyroid Cancer

  2020cites this paper
• Perspective: Do Fasting, Caloric Restriction, and Diets Increase Sensitivity to Radiotherapy? A Literature Review.

  2020cites this paper
• Hydroxyapatite-based materials for smart antitumor drug delivery systems, endocytic pathways and endosomal trafficking : polymers and biopolymers

  2019cites this paper
• Targeting Energy Metabolism by a Platinum(IV) Prodrug as an Alternative Pathway for Cancer Suppression.

  2019cites this paper
• Carcinogenesis with mitochondrial respiratory degeneration was testified using a specific herbal medicine

  2019cites this paper
• Intérêt de l’utilisation de stratégies anti-métaboliques pour le traitement du cancer du sein

  2019cites this paper
• Cancer Etiology: A Metabolic Disease Originating from Life's Major Evolutionary Transition?

  2019cites this paper
• How to obtain severe hypoglycemia without causing brain or cardiac damage.

  2019cites this paper
• Metabolic reprogramming in breast cancer results in distinct mitochondrial bioenergetics between luminal and basal subtypes

  2019cites this paper
• Inhibition of phosphoenolpyruvate carboxykinase blocks lactate utilization and impairs tumor growth in colorectal cancer

  2019cites this paper
• The mechanistic link between type 2 diabetes and colorectal cancer

  2019cites this paper
• Tumor Energy Metabolism and Potential of 3-Bromopyruvate as an Inhibitor of Aerobic Glycolysis: Implications in Tumor Treatment

  2019cites this paper
• Mitochondrial determinants of chemoresistance

  2019cites this paper
• Anticancerous Plant Compounds Affecting the Power House of Cancerous Cells: A Possible Herbal Mitocan

  2018cites this paper
• Given the continuing dispute over the role of genetic abnormalities and protracted mitochondrial respiratory dysfunction in carcinogenesis, what is the core underlying entity?

  2018cites this paper
• Regulation of Mitochondrial Energy Metabolism

  2018cites this paper
• 2,3-Dimethoxy-5-methyl-p-benzoquinone (Coenzyme Q0) Disrupts Carbohydrate Metabolism of HeLa Cells by Adduct Formation with Intracellular Free Sulfhydryl-Groups, and Induces ATP Depletion and Necrosis.

  2018cites this paper
• Mitochondrial DNA variations in tongue squamous cell carcinoma.

  2018cites this paper
• Erastin-Like Anti-Warburg Agents Prevent Mitochondrial Depolarization Induced by Free Tubulin and Decrease Lactate Formation in Cancer Cells

  2018cites this paper
• VDAC Regulation: A Mitochondrial Target to Stop Cell Proliferation.

  2018cites this paper
• How the Warburg effect supports aggressiveness and drug resistance of cancer cells?

  2018cites this paper
• 3‐Bromopyruvate as a potent anticancer therapy in honor and memory of the late Professor André Goffeau

  2018cites this paper
• Cellular responses to piotodynamic therapy

  2017cites this paper
• Bioenergetics of Human Cancer Cells and Normal Cells During Proliferation and Differentiation

  2017cites this paper
• Chapter 17 GlucoCEST: Imaging Glucose in Tumors

  2017cites this paper
• Theories of Aging and Chronic Diseases: Chronic Inflammation an Interdependent ‘Roadmap’ to Age-Associated Illnesses

  2017cites this paper
• Induction of Mitochondrial Dysfunction and Oxidative Damage by Antibiotic Drug Doxycycline Enhances the Responsiveness of Glioblastoma to Chemotherapy

  2017cites this paper
• Isoprenoids responsible for protein prenylation modulate the biological effects of statins on pancreatic cancer cells

  2017cites this paper
• Genetic alterations in Krebs cycle and its impact on cancer pathogenesis.

  2017cites this paper
• VDAC–Tubulin, an Anti-Warburg Pro-Oxidant Switch

  2017cites this paper
• Induction and Detection of Oncogene-Induced Cellular Senescence in Drosophila.

  2017cites this paper
• Bioenergetic Adaptations in Chemoresistant Ovarian Cancer Cells

  2017cites this paper
• Drosophila as a Model to Study the Link between Metabolism and Cancer

  2017cites this paper
• The systemic tumor response to RNase A treatment affects the expression of genes involved in maintaining cell malignancy

  2017cites this paper
• Press-pulse: a novel therapeutic strategy for the metabolic management of cancer

  2017cites this paper
• Chapter 1 Understanding Mitochondrial DNA in Brain Tumorigenesis

  2017cites this paper
• Voltage-Dependent Anion Channels and Tubulin: Bioenergetic Controllers in Cancer Cells

  2017cites this paper
• pH, Lactate, and Hypoxia: Reciprocity in Regulating High-Affinity Monocarboxylate Transporter Expression in Glioblastoma

  2017cites this paper
• Investigation of brain tumour metabolism using naturally occurring chemical exchange saturation transfer agents with magnetic resonance imaging

  2016cites this paper
• Gene Network Modeling of Cancer Metabolism by Linglin

  2016cites this paper
• Characterisation of the fundamental function(s) of bovine serum albumin in the culture of NS0 cells

  2016cites this paper
• Whole-genome DNA methylation and hydroxymethylation profiling for HBV-related hepatocellular carcinoma.

  2016cites this paper
• Dissecting cellular senescence and SASP in Drosophila

  2016cites this paper
• Increased Expression of MCT 4 and GLUT1 in Early Events of Spheroid Formation of Adenocarcinomic Epithelial Cells A 549

  2016cites this paper
• THERAPEUTIC EFFECT OF TRIDHAM AND 1,2,3,4,6-PENTA-O-GALLOYL-Β-D-GLUCOSE ON ALTERED ENERGY METABOLISM IN MAMMARY CARCINOMA BEARING RATS

  2016cites this paper
• Investigating the Effect of Energy Substrates and LPS-activation on the In Vitro Energy Metabolism of BV-2, RAW264.7 and VM-M3 Cells

  2016cites this paper
• The reduced concentration of citrate in cancer cells: An indicator of cancer aggressiveness and a possible therapeutic target.

  2016cites this paper
• ATP/ADP Turnover and Import of Glycolytic ATP into Mitochondria in Cancer Cells Is Independent of the Adenine Nucleotide Translocator *

  2016cites this paper
• A combined approach against tumorigenesis using glucose deprivation and mitochondrial complex 1 inhibition by rotenone

  2016cites this paper
• The HK2 Dependent “Warburg Effect” and Mitochondrial Oxidative Phosphorylation in Cancer: Targets for Effective Therapy with 3-Bromopyruvate

  2016influential citation
• Ameliorating effect of Kalpaamruthaa on altered energy metabolism in BCR-ABL+ cell line induced leukemic mouse model

  2016cites this paper
• Non-autonomous Tumor Progression by Oncogenic Inflammation

  2016cites this paper
• Cellular energetics as a target for tumor cell elimination

  2016cites this paper
• Targeting tumor glycolysis by a mitotropic agent

  2016cites this paper
• Doxycycline inhibits proliferation and induces apoptosis of both human papillomavirus positive and negative cervical cancer cell lines.

  2016cites this paper
• Dysregulated metabolism contributes to oncogenesis

  2015cites this paper
• Understanding Mitochondrial DNA in Brain Tumorigenesis

  2015cites this paper
• Mitochondrial Alteration: A Major Player in Carcinogenesis

  2015cites this paper
• Toluquinol, A Marine Fungus Metabolite, Inhibits Some of the Hallmarks of Cancer

  2015cites this paper
• Bis(monoacylglycero)phosphate (BMP), a novel macrophage associated phospholipid: Implications in gangliosidoses and cancer

  2015influential citation
• Breast Cancer Metabolism and Mitochondrial Activity: The Possibility of Chemoprevention with Metformin

  2015cites this paper