Constitutive Expression of Interleukin‐7 mRNA and Production of IL‐7 by a Cloned Murine Thymic Stromal Cell Line

No abstract is available for this paper.

• Publication year

  1990

• Venue

  Journal of Leukocyte Biology

• Publication date

  1990-09-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1002/jlb.48.3.205PMID 2144014
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Model for clonal elimination in the thymus.

  1989cited by this paper
• Interleukin 7 production and function in stromal cell-dependent B cell development

  1989cited by this paper
• In vitro effects of recombinant interleukin 7 on growth and differentiation of bone marrow pro-B- and pro-T-lymphocyte clones and fetal thymocyte clones.

  1989cited by this paper
• Capacities of a Newly Established Thymic Stromal Cell Clone to Express la Antigens and to Produce Interleukin‐6, Colony‐Stimulating Factor, and Thymic Stroma‐Derived T‐Cell Growth Factor

  1989cited by this paper
• Recombinant interleukin 7, pre-B cell growth factor, has costimulatory activity on purified mature T cells

  1989cited by this paper
• Thymic stroma-derived T cell growth factor (TSTGF). IV. Capacity of TSTGF to promote the growth of L3T4- Lyt-2- thymocytes by synergy with phorbol myristate acetate or various IL.

  1989cited by this paper
• Human interleukin 7: molecular cloning and growth factor activity on human and murine B-lineage cells.

  1989cited by this paper
• Thymic Stroma‐Derived T‐Cell Growth Factor (TSTGF): II. Biochemical and Functional Characterization

  1988cited by this paper
• Stimulation of B-cell progenitors by cloned murine interleukin-7

  1988cited by this paper
• Molecular regulation of B lymphocyte response.

  1988cited by this paper
• Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase.

  1988cited by this paper
• B cell precursor growth-promoting activity. Purification and characterization of a growth factor active on lymphocyte precursors

  1988cited by this paper
• B lymphopoiesis on stromal cell clone: stromal cell clones acting on different stages of B cell differentiation*

  1988cited by this paper
• Thymic stroma-derived T cell growth factor (TSTGF). I. Functional distinction of TSTGF from interleukins 2 and 4 and its preferential growth-promoting effect on helper T cell clones.

  1987cited by this paper
• Production of recombinant human pancreatic secretory trypsin inhibitor by Escherichia coli.

  1987cited by this paper
• Partial purification and characterization of a factor from a cloned thymic epithelium cell line.

  1986cited by this paper
• Use of a cDNA expression vector for isolation of mouse interleukin 2 cDNA clones: expression of T-cell growth-factor activity after transfection of monkey cells.

  1985cited by this paper
• Number and organization of actin-related sequences in the mouse genome.

  1983cited by this paper
• A simple and very efficient method for generating cDNA libraries.

  1983cited by this paper
• Induction of T-cell maturation by a cloned line of thymic epithelium (TEPI).

  1983cited by this paper
• Functional Activity of a Transformed Thymic Epithelial Cell Line

  1983cited by this paper
• Distinct effects of thymic epithelial culture supernatants on T cell properties of mouse thymocytes separated by the use of peanut agglutinin.

  1979cited by this paper
• Cloning and complete nucleotide sequence of mouse immunoglobulin gamma 1 chain gene.

  1979cited by this paper
• Thymic factors and T cell maturation in vitro: a comparison of the effects of thymic epithelial cultures with thymic extracts and thymus dependent serum factors.

  1979cited by this paper
• DNA sequencing with chain-terminating inhibitors.

  1977cited by this paper
• The role of thymus epithelial reticular cells in viral leukemogenesis.

  1968cited by this paper
• Current concepts of the immunological function of the thymus.

  1967cited by this paper

• Interleukin-7 potentiates MAPK10-elicited host-protective vaccine against Leishmania donovani.

  2023cites this paper
• Research Note: Characterization of monoclonal antibodies and development of sandwich ELISA for detecting chicken IL7

  2021cites this paper
• Homeostasis of Naive and Memory T Lymphocytes.

  2021cites this paper
• Bacteria-Induced Group 2 Innate Lymphoid Cells in the Stomach Provide Immune Protection through Induction of IgA.

  2020cites this paper
• Strategies to Improve Posttransplant Immunity

  2019cites this paper
• Interleukin‐7 Availability Is Maintained by a Hematopoietic Cytokine Sink Comprising Innate Lymphoid Cells and T Cells

  2017cites this paper
• Potential implications of interleukin-7 in chronic wound healing

  2016cites this paper
• MECHANISMS OF LOW DOSE ARSENIC LYMPHOID STEM CELL IMMUNOTOXICITY AND POTENTIAL INTERACTIONS WITH DIBENZO[def, p]CHRYSENE (DBC)

  2015cites this paper
• Human dermal injury age estimation through messenger RNA expression

  2014cites this paper
• From THE DEPARTMENT OF MICROBIOLOGY, TUMOR AND CELL BIOLOGY Karolinska Institutet, Stockholm, Sweden

  2014cites this paper
• Molecular mechanisms of versatile biological activity of interleukin-7

  2014cites this paper
• IL-7R-mediated signaling in T-cell acute lymphoblastic leukemia.

  2013cites this paper
• Strategies to improve post-transplant immunity

  2013cites this paper
• Recombinant human interleukin-7 (CYT107) promotes T-cell recovery after allogeneic stem cell transplantation.

  2012cites this paper
• Osteoblast‐specific overexpression of human interleukin‐7 rescues the bone mass phenotype of interleukin‐7–deficient female mice

  2012cites this paper
• Expression of IL-7 receptor in human peripheral regulatory T cells

  2012cites this paper
• JunD/AP-1-Mediated Gene Expression Promotes Lymphocyte Growth Dependent on Interleukin-7 Signal Transduction

  2012cites this paper
• Signals Delivered By Interleukin-7 Regulate The Activities Of Bim And Jund In T Lymphocytes

  2012cites this paper
• after allogeneic stem cell transplantation Recombinant human interleukin-7 (CYT107) promotes T-cell recovery

  2012cites this paper
• Recombinant human interleukin-7 ( CYT 107 ) promotes T-cell recovery after allogeneic stem cell transplantation

  2012cites this paper
• Effect of age on homeostasis of lymphocytes in an interleukin-7-deficient mouse model.

  2011cites this paper
• Improvement of Thymopoiesis after Hematopoietic Stem Cell Transplantation by Cytokines: Translational studies in experimental animal models

  2011influential citation
• Targeting of active mTOR inhibits primary leukemia T cells and synergizes with cytotoxic drugs and signaling inhibitors.

  2011cites this paper
• Peripheral Interactions with APCs Conversion of Human T Cells Depend on Homeostatic Expansion and Phenotypic

  2010cites this paper
• Homeostatic Expansion and Phenotypic Conversion of Human T Cells Depend on Peripheral Interactions with APCs

  2010cites this paper
• IL-7 receptor is expressed on adult pre-B-cell acute lymphoblastic leukemia and other B-cell derived neoplasms and correlates with expression of proliferation and survival markers.

  2010cites this paper
• Rejuvenation of the aging T cell compartment.

  2009cites this paper
• Thymic involution and immune reconstitution.

  2009cites this paper
• Differential cytokine mRNA expression in single lymphatic follicles of the calf ileal and jejunal Peyer's patches.

  2009cites this paper
• Fluorescent virus-like particles as novel platform to identify immune-receptor / ligand interactions on leukocyte subsets angestrebter akademischer

  2009cites this paper
• Interleukin 7 receptor α as a potential therapeutic target in transplantation

  2009cites this paper
• The C ontribution of Homeostatically Expanded Donor CD8 T Cells to Host Reconstitution Following Syngeneic Hematopoietic Cell Transplantation

  2008cites this paper
• Interleukin-7 immunotherapy.

  2007cites this paper
• Differential cytokine gene expression in CD4+ and CD8+ T cell subsets of calves.

  2007cites this paper
• Clinical strategies to enhance T cell reconstitution.

  2007cites this paper
• Nanochemistry-based immunotherapy for HIV-1.

  2007cites this paper
• Functional Deficiency in IL-7 Caused by an N-Ethyl-N-nitrosourea-Induced Point Mutation

  2007cites this paper
• Immunomodulatory Molecules of the Immune System

  2007cites this paper
• General Principles of Tumor Immunotherapy

  2007cites this paper
• Functional deficiency in IL-7 caused by an ENU-induced point mutation (82.11)

  2007cites this paper
• Long‐term Haematopoietic Reconstitution and Survival without Interleukin‐7 in a Murine Syngeneic Bone Marrow Transplantation Model

  2006cites this paper
• Reduced Tumorigenicity of Murine Tumor Cells Secreting Is Due to Nonspecific Host Responses and Is Unrelated to Class I Major Histocompatibility Complex Expression1

  2006cites this paper
• Lymphocyte dynamics in health and disease

  2006cites this paper
• The IL-7/IL-7 receptor axis: understanding its central role in T-cell homeostasis and the challenges facing its utilization as a novel therapy.

  2006cites this paper
• interleukin 7 : implications for clinical application

  2005cites this paper
• Thymopoiesis following allogeneic stem cell transplantation: new possibilities for improvement.

  2005cites this paper
• IL-7: maintaining T-cell memory and achieving homeostasis.

  2005cites this paper
• A dose effect of IL-7 on thymocyte development.

  2004cites this paper
• Host Conditioning Is a Primary Determinant in Modulating the Effect of IL-7 on Murine Graft-versus-Host Disease1

  2004cites this paper
• Cytokines in the thymus: production and biological effects.

  2004cites this paper
• Die Bedeutung von Interleukin-7 für die hämatopoetische Rekonstitution nach Knochenmarktransplantation

  2004cites this paper
• Graft-versus-Host Disease in Modulating the Effect of IL-7 on Murine Host Conditioning Is a Primary Determinant

  2004cites this paper
• CHAPTER 13 – INTERLEUKIN-7

  2003cites this paper
• Interleukln 7 Induces Preferential Expansion of V 38 . 2 + CD 4-8-and V 38 . 2 + CD 4 + 8-Murine Thymocytes Positively Selected by Class I Molecules

  2003cites this paper
• Enhancement of IL-7 following irradiation of fetal thymus.

  2003cites this paper
• Biochemical characterization of heparan sulfate derived from murine hemopoietic stromal cell lines: A bone marrow‐derived cell line S17 and a fetal liver‐derived cell line AFT024

  2002cites this paper
• Interleukin-7: from bench to clinic.

  2002cites this paper
• Analyse von Funktionen des prä-B-Zell-Rezeptors anhand induzierbarer Expression von Immunglobulin-Schweren-Ketten

  2001cites this paper
• Biological and clinical implications of interleukin-7 and lymphopoiesis.

  1999cites this paper
• High-Level Replication of Human Immunodeficiency Virus in Thymocytes Requires NF-κB Activation through Interaction with Thymic Epithelial Cells

  1999cites this paper
• Reviewing the potential utility of interleukin-7 as a promoter of thymopoiesis and immune recovery.

  1998cites this paper
• General classes and functions of four-helix bundle cytokines.

  1998cites this paper
• Immunologic abnormalities exhibited in IL-7 transgenic mice with dermatitis.

  1998cites this paper
• Lymphokines and Cytokines

  1998cites this paper
• Interleukin-7-enhanced cytotoxic T lymphocyte activity after viral infection in marrow transplanted mice

  1997cites this paper
• Autocrine expression of interleukin‐7 rescues lymphoid expansion in interleukin‐7‐deficient mice

  1997cites this paper
• Stimulation of immune reconstitution by interleukin-7 after syngeneic bone marrow transplantation in mice.

  1996cites this paper
• Interleukin‐7. Biology and implications for dermatology

  1996cites this paper
• Clinical needs for hematopoietic growth factors: old and new.

  1996cites this paper
• Interleukin-7 inhibits apoptosis of mouse malignant T-lymphoma cells by both suppressing the CPP32-like protease activation and inducing the Bcl-2 expression.

  1996cites this paper
• IL-7 reverses NK1+ T cell-defective IL-4 production in the non-obese diabetic mouse.

  1996cites this paper
• Transgenic expression of interleukin 7 restores T cell populations in nude mice

  1995cites this paper
• Induction of IgA B cell differentiation of bone marrow-derived B cells by Peyer's patch autoreactive helper T cells.

  1995cites this paper
• Interleukin-7 and lymphopoiesis: biological and clinical implications.

  1995cites this paper
• [Interleukin 7 in dermatology. Molecular, immunologic and preclinical aspects].

  1995cites this paper
• Opposite actions of transforming growth factor-beta 1 on the gene expression of atrial natriuretic peptide biological and clearance receptors in a murine thymic stromal cell line.

  1995cites this paper
• Diverse immunological and hematological effects of interleukin 7: implications for clinical application

  1995cites this paper
• Cloning and expression of a cDNA encoding ovine interleukin 7.

  1995cites this paper
• A thymic stromal cell line supports in vitro development of surface IgM+ B cells and produces a novel growth factor affecting B and T lineage cells.

  1994cites this paper
• Developmental expression of the mouse c-rel proto-oncogene in hematopoietic organs.

  1994cites this paper
• Establishment and characterization of nurse cell-like clones from human skin. Nurse cell-like clones can stimulate autologous mixed lymphocyte reaction.

  1994cites this paper
• Interleukin 7 induces preferential expansion of V beta 8.2+CD4-8- and V beta 8.2+CD4+8- murine thymocytes positively selected by class I molecules

  1994cites this paper
• Interleukin‐7 regulates c‐myc expression in murine T cells and thymocytes: a role for tyrosine kinase(s) and calcium mobilization

  1994cites this paper
• Endogenous granulocyte-macrophage colony-stimulating factor is involved in IL-1- and IL-7-induced murine thymocyte proliferation.

  1994cites this paper
• Interleukin-7, a major T-lymphocyte cytokine.

  1993cites this paper
• Differential immuno-suppressive effects of metabolic inhibitors on T-lymphocyte activation.

  1993cites this paper
• A novel cytokine-responsive cell surface glycoprotein defines a subset of medullary thymic epithelium in situ.

  1993cites this paper
• Interleukin-7 promotes the generation of phenotypically mature CD45RA positive human thymocytes in vitro.

  1993cites this paper
• The development of dermatitis infiltrated by gamma delta T cells in IL-7 transgenic mice.

  1993cites this paper
• Keratinocyte-derived IL-7 serves as a growth factor for dendritic epidermal T cells in mice.

  1993cites this paper
• Thymic stroma-derived T-cell inhibitory factor (TSTIF). 2: TSTIF acts on the antigen-presenting cell to inhibit antigen-stimulated T-cell proliferation.

  1993cites this paper
• Interleukin-7: biology and potential clinical applications.

  1993cites this paper
• Thymic stroma-derived T-cell inhibitory factor (TSTIF) 1. TSTIF induces inhibition of antigen-stimulated T-cell proliferation.

  1993cites this paper
• Interleukin-7 is a potent co-stimulus of the adhesion pathway involving CD2 and CD28 molecules.

  1993cites this paper
• The cytokines: physiological and pathophysiological aspects.

  1993cites this paper
• Identification of IL-7-dependent bone marrow-derived Thy-1-B220- lymphoid cell clones that rearrange and express both Ig and T cell receptor genes.

  1992cites this paper
• Thymic hyperplasia in transgenic mice caused by immortal epithelial cells expressing c‐kit ligand

  1992cites this paper
• In vitro induction of CD8 expression on thymic pre-T cells. II. Characterization of CD3-CD4-CD8 alpha + cells generated in vitro by culturing CD25+CD3-CD4-CD8- thymocytes with T cell growth factor-beta and tumor necrosis factor-alpha.

  1992cites this paper
• IL-7 is requisite for IL-1-induced thymocyte proliferation. Involvement of IL-7 in the synergistic effects of granulocyte-macrophage colony-stimulating factor or tumor necrosis factor with IL-1.

  1992cites this paper
• Characterization of an antigenic determinant preferentially expressed by type I epithelial cells in the murine thymus.

  1992cites this paper