Genome-wide linkage analysis of families with obsessive-compulsive disorder ascertained through pediatric probands.

No abstract is available for this paper.

• Publication year

  2002

• Venue

  American journal of medical genetics

• Publication date

  2002-07-08

• Fields of study

  Medicine, Psychology

• Identifiers
  DOI 10.1002/AJMG.10519PMID 12116192
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2001cited by this paper
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  2001cited by this paper
• The genetics of Graves' disease.

  2000cited by this paper
• Complex segregation analysis provides compelling evidence for a major gene underlying obsessive-compulsive disorder and for heterogeneity by sex.

  2000influential reference
• Significant linkage for Tourette syndrome in a large French Canadian family.

  2000cited by this paper
• The genetics of Hashimoto's disease.

  2000cited by this paper
• Obsessive compulsive disorder in childhood.

  2000cited by this paper
• Mutation screening of human 5-HT(2B)receptor gene in early-onset obsessive-compulsive disorder.

  2000cited by this paper
• Association of the serotonin transporter promoter regulatory region polymorphism and obsessive-compulsive disorder

  1999influential reference
• Genetic susceptibility to the connective tissue diseases.

  1999cited by this paper
• Genetics of Type 1 diabetes mellitus.

  1999cited by this paper
• Complex segregation analysis for obsessive compulsive disorder and related disorders.

  1999influential reference
• A complete genome screen in sib pairs affected by Gilles de la Tourette syndrome. The Tourette Syndrome Association International Consortium for Genetics.

  1999cited by this paper
• Segregation analysis of obsessive-compulsive disorder using symptom-based factor scores.

  1999cited by this paper
• Evidence for linkage disequilibrium between serotonin transporter protein gene (SLC6A4) and obsessive compulsive disorder

  1998influential reference
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  1998influential reference
• Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections: clinical description of the first 50 cases.

  1998cited by this paper
• The power to detect linkage in complex disease by means of simple LOD-score analyses.

  1998cited by this paper
• Is juvenile obsessive-compulsive disorder a developmental subtype of the disorder? A review of the pediatric literature.

  1998cited by this paper
• Autism, affective and other psychiatric disorders: patterns of familial aggregation

  1998cited by this paper
• Serotonin Transporter and Seasonal Variation in Blood Serotonin in Families with Obsessive-Compulsive Disorder

  1998cited by this paper
• Coupling of optimized multiplex PCR and automated capillary electrophoresis for efficient genome-wide searches

  1998cited by this paper
• Cross-National Epidemiology of Obsessive-Compulsive Disorder

  1998cited by this paper
• Familial aggregation and phenomenology of 'early'-onset (at or before age 20 years) panic disorder.

  1997cited by this paper
• Allele-sharing models: LOD scores and accurate linkage tests.

  1997influential reference
• Parametric and nonparametric linkage analysis: a unified multipoint approach.

  1996influential reference
• Genetic dissection of complex traits

  1996cited by this paper
• Demographic and clinical features of obsessive-compulsive disorder in children and adolescents.

  1995cited by this paper
• Obsessive-compulsive disorder in a birth cohort of 18-year-olds: prevalence and predictors.

  1995cited by this paper
• Whole blood serotonin and disruptive behaviors in juvenile obsessive-compulsive disorder.

  1995cited by this paper
• Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results

  1995cited by this paper
• A family study of obsessive-compulsive disorder.

  1995cited by this paper
• Research on the treatment of sexually abused children: a review and recommendations.

  1995cited by this paper
• Genome scan for linkage to Gilles de la Tourette syndrome.

  1994cited by this paper
• The Yale-Brown Obsessive-Compulsive Scale: measures of internal consistency.

  1994cited by this paper
• Test-retest reliability of team consensus best-estimate diagnoses of axis I and II disorders in a family study.

  1994cited by this paper
• Diagnostic and Statistical Manual of Mental Disorders, 4th Ed.

  1994cited by this paper
• Haloperidol addition in fluvoxamine-refractory obsessive-compulsive disorder. A double-blind, placebo-controlled study in patients with and without tics.

  1994cited by this paper
• Genetic dissection of complex traits.

  1994cited by this paper
• Tic-related vs. non-tic-related obsessive compulsive disorder.

  1994cited by this paper
• The cross national epidemiology of obsessive compulsive disorder. The Cross National Collaborative Group.

  1994cited by this paper
• Frequency of obsessive-compulsive disorder in a community sample of young adolescents.

  1994cited by this paper
• Prevalence of psychiatric disorders in a community population of older adolescents.

  1993cited by this paper
• Obsessive‐compulsive disorder in children and adolescents

  1993cited by this paper
• An epidemiological study of obsessive-compulsive disorder and related disorders in Israeli adolescents.

  1992cited by this paper
• Sensitivity of lod scores to changes in diagnostic status.

  1992cited by this paper
• The Structured Clinical Interview for DSM-III-R (SCID). II. Multisite test-retest reliability.

  1992cited by this paper
• The Structured Clinical Interview for DSM-III-R (SCID). I: History, rationale, and description.

  1992cited by this paper
• The Structured Clinical Interview for DSM-III-R (SCID). II. Multisite test-retest reliability.

  1992cited by this paper
• How reliable are operationalized diagnosis? The test-retest reliability of Structured Clinical Interview for DSM-III-R (SCID)

  1992cited by this paper
• A family study of obsessive-compulsive disorder.

  1992cited by this paper
• Tics and Tourette's disorder: a 2- to 7-year follow-up of 54 obsessive-compulsive children.

  1992cited by this paper
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  1992cited by this paper
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  1992cited by this paper
• Prolactin in childhood obsessive-compulsive disorder: clinical correlates and response to clomipramine.

  1991cited by this paper
• Gender-Divergent Aetiological Factors in Obsessive-Compulsive Disorder

  1991cited by this paper
• A family study of Gilles de la Tourette syndrome.

  1991cited by this paper
• 9p monosomy in a patient with Gilles de la Tourette's syndrome

  1991cited by this paper
• Schizophrenia: age at onset, gender and familial risk

  1990cited by this paper
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  1990cited by this paper
• Age at onset of selected mental disorders in five community populations.

  1990cited by this paper
• Evidence for a General Neurotic Syndrome

  1990cited by this paper
• The genetics of six neurotic disorders: a twin study.

  1990cited by this paper
• Psychiatric disorders in first degree relatives of children and adolescents with obsessive compulsive disorder.

  1990cited by this paper
• Obsessive-compulsive disorder in children and adolescents

  1989cited by this paper
• The Yale-Brown Obsessive Compulsive Scale. I. Development, use, and reliability.

  1989cited by this paper
• Obsessive—compulsive disorder in childhood☆

  1989cited by this paper
• The Yale-Brown Obsessive Compulsive Scale. II. Validity.

  1989cited by this paper
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  1989cited by this paper
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  1988cited by this paper
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  1988cited by this paper
• Obsessive compulsive disorder in adolescence: an epidemiological study.

  1988cited by this paper
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  1986cited by this paper
• The inheritance of Gilles de la Tourette's syndrome and associated behaviors. Evidence for autosomal dominant transmission.

  1986cited by this paper
• Effects of misspecifying genetic parameters in lod score analysis.

  1986cited by this paper
• A twin study of Tourette syndrome.

  1985cited by this paper
• Genetic and environmental influences on obsessional traits and symptoms

  1984cited by this paper
• Genetic factors in anxiety disorders.

  1983cited by this paper
• Best estimate of lifetime psychiatric diagnosis: a methodological study.

  1982cited by this paper
• Linkage analysis with misclassification at one locus

  1977cited by this paper
• A family study of Gilles de la Tourette syndrome.

  1976cited by this paper
• Genetics of Graves' disease.

  1972cited by this paper
• SIMILAR AND DISSIMILAR MANIFESTATIONS OF OBSESSIVE-COMPULSIVE NEUROSES IN MONOZYGOTIC TWINS.

  1965cited by this paper

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  2021cites this paper
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  2021cites this paper
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  2021cites this paper
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  2021cites this paper
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