IL-18 and Cutaneous Inflammatory Diseases

Interleukin (IL)-18, an IL-1 family cytokine, is a pleiotropic immune regulator. IL-18 plays a strong proinflammatory role by inducing interferon (IFN)-γ. Previous studies have implicated IL-18 in the pathogenesis of various diseases. However, it is not well understood biologic activities of IL-18 in the diverse skin diseases. Here, we have reviewed the expression and function of IL-18 in skin diseases including inflammatory diseases. This article provides an evidence-based understanding of the role of IL-18 in skin diseases and its relationship with disease activities.

• Publication year

  2015

• Venue

  International Journal of Molecular Sciences

• Publication date

  2015-12-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.3390/ijms161226172PMID 26690141PMCID 4691115
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Immunoglobulin e, interleukin-18 and interleukin-12 in patients with atopic dermatitis: correlation with disease activity.

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• The role of cytokines in the pathogenesis of cutaneous lupus erythematosus.

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• Inflammasomes and human autoimmunity: A comprehensive review.

  2015influential reference
• The Relationship between Interleukin-18 Polymorphisms and Allergic Disease: A Meta-Analysis

  2014cited by this paper
• The inflammasome and lupus: another innate immune mechanism contributing to disease pathogenesis?

  2014influential reference
• Study of serum interleukin (IL) 18 and IL-6 levels in relation with the clinical disease severity in chronic idiopathic urticaria patients of Kashmir (North India)

  2014cited by this paper
• Innate and intrinsic antiviral immunity in skin.

  2014influential reference
• Role of ROS and HMGB1 in contact allergen-induced IL-18 production in human keratinocytes.

  2014cited by this paper
• Guidelines of care for the management of atopic dermatitis: Section 4. Prevention of disease flares and use of adjunctive therapies and approaches.

  2014cited by this paper
• Effects of topical application of a recombinant staphylococcal enterotoxin A on DNCB and dust mite extract-induced atopic dermatitis-like lesions in a murine model

  2014cited by this paper
• Guidelines of care for the management of atopic dermatitis: section 1. Diagnosis and assessment of atopic dermatitis.

  2014cited by this paper
• Association Between Interleukin 18 Polymorphisms and Alopecia Areata in Koreans

  2014cited by this paper
• Allergic contact dermatitis beyond IL‐1β role of additional family members

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• High serum concentration of interleukin-18 in diabetic patients with foot ulcers.

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• Why does allergic contact dermatitis exist?

  2013cited by this paper
• Keratin 16 regulates innate immunity in response to epidermal barrier breach

  2013cited by this paper
• Free IL-18 and IL-33 cytokines in chronic spontaneous urticaria.

  2013cited by this paper
• Interleukin-18 and IL-18 Binding Protein

  2013cited by this paper
• IL-27 Regulates IL-18 Binding Protein in Skin Resident Cells

  2012cited by this paper
• Keratin 1 maintains skin integrity and participates in an inflammatory network in skin through interleukin-18

  2012cited by this paper
• IL‐17‐producing γδ T cells and innate lymphoid cells

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• Interleukin‐18 system plays an important role in keloid pathogenesis via epithelial–mesenchymal interactions

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• M‐CSF induces the expression of a membrane‐bound form of IL‐18 in a subset of human monocytes differentiating in vitro toward macrophages

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• Hiding under the skin: A welcome surprise in psoriasis

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• Cutaneous manifestations associated with adult-onset Still’s disease: important diagnostic values

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• Interleukin‐18 is elevated in the horny layer in patients with atopic dermatitis and is associated with Staphylococcus aureus colonization

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• A functional promoter polymorphism of the human IL18 gene is associated with aspirin‐induced urticaria

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• Contrasting roles of the IL-1 and IL-18 receptors in MyD88-dependent contact hypersensitivity.

  2010cited by this paper
• Clinicopathologic characteristics of cutaneous chronic graft‐versus‐host diseases: a retrospective study in Korean patients

  2010cited by this paper
• Alopecia areata update: part I. Clinical picture, histopathology, and pathogenesis.

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• Psoriasis

  2010cited by this paper
• Serum levels of IL‐18 and sIL‐2R in patients with alopecia areata receiving combined therapy with oral cyclosporine and steroids

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• The inflammasome, an innate immunity guardian, participates in skin urticarial reactions and contact hypersensitivity.

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• IL-18 downregulates collagen production in human dermal fibroblasts via the ERK pathway.

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• Association of interleukin-18 promoter polymorphisms with WHO pathological classes and serum IL-18 levels in Chinese patients with lupus nephritis

  2009influential reference
• IL-18 and skin inflammation.

  2009cited by this paper
• Guidelines for the management of contact dermatitis: an update

  2009cited by this paper
• Corticotropin‐releasing factor decreases IL‐18 in the monocyte‐derived dendritic cell

  2009cited by this paper
• Free circulating interleukin-18 is increased in Schnitzler syndrome: a new autoinflammatory disease?

  2009cited by this paper
• Role of corticotropin-releasing hormone and receptor in the pathogenesis of psoriasis.

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  2008cited by this paper
• IL-18 induces a marked gene expression profile change and increased Ccl1 (I-309) production in mouse mucosal mast cell homologs.

  2008cited by this paper
• Atopic dermatitis.

  2008cited by this paper
• Evidence for a pathogenetic role of interleukin-18 in cutaneous lupus erythematosus.

  2008influential reference
• Atopic dermatitis in adults: evaluation of peripheral blood mononuclear cells proliferation response to Staphylococcus aureus enterotoxins A and B and analysis of interleukin‐18 secretion

  2008cited by this paper
• IL‐18 is a key proximal mediator of contact hypersensitivity and allergen‐induced Langerhans cell migration in murine epidermis

  2008cited by this paper
• IL‐1, IL‐18, and IL‐33 families of cytokines

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• The activity of caspase-1 is increased in lesional psoriatic epidermis.

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• Serum interleukin‐18 in patients with chronic ordinary urticaria: association with disease activity

  2007cited by this paper
• Stress in patients with alopecia areata and vitiligo

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• Activation of the IL-1beta-processing inflammasome is involved in contact hypersensitivity.

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• Disease association of the interleukin-18 promoter polymorphisms in Taiwan Chinese systemic lupus erythematosus patients

  2007influential reference
• Expression of the corticotropin‐releasing hormone–proopiomelanocortin axis in the various clinical types of psoriasis

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  2006cited by this paper
• Human β-defensins

  2006cited by this paper
• IL-18 in autoimmunity: review.

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• Contribution of IL-18 to atopic-dermatitis-like skin inflammation induced by Staphylococcus aureus product in mice.

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• Human Mast Cell Chymase Cleaves Pro-IL-18 and Generates a Novel and Biologically Active IL-18 Fragment1

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• Immunoreactivity of corticotropin‐releasing hormone, adrenocorticotropic hormone and α‐melanocyte‐stimulating hormone in alopecia areata

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• Corticotropin-releasing hormone (CRH) downregulates interleukin-18 expression in human HaCaT keratinocytes by activation of p38 mitogen-activated protein kinase (MAPK) pathway.

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• Immunohistochemical characterization of cutaneous drug eruptions by STI571.

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• Differences in signaling pathways by IL-1beta and IL-18.

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• IL-1 and IL-18 receptors, and their extended family.

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• Expression of Interleukin (IL)-18 and Functional IL-18 Receptor on Human Vascular Endothelial Cells, Smooth Muscle Cells, and Macrophages

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• Expression of IL-18 in psoriasis

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• The allergenic yeast Malassezia furfur induces maturation of human dendritic cells

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• Interleukin-18 Regulates Acute Graft-Versus-Host Disease by Enhancing Fas-mediated Donor T Cell Apoptosis

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• Interleukin-18 regulates both Th1 and Th2 responses.

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• Interleukin-18 Is Elevated in the Sera from Patients with Atopic Dermatitis and from Atopic Dermatitis Model Mice, NC/Nga

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• Progressive accumulation of hyperinflammatory NKG2Dlow NK cells in early life defines a novel endotype of severe atopic dermatitis

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• Mendelian randomization studies in atopic dermatitis: a systematic review.

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