The SPT6 gene is essential for growth and is required for delta-mediated transcription in Saccharomyces cerevisiae

No abstract is available for this paper.

• Publication year

  1987

• Venue

  Molecular and Cellular Biology

• Publication date

  1987-02-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1128/mcb.7.2.679-686.1987PMID 3029564PMCID PMC365124
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Analysis of mutations affecting Ty-mediated gene expression in Saccharomyces cerevisiae

  2004cited by this paper
• SSN20 is an essential gene with mutant alleles that suppress defects in SUC2 transcription in Saccharomyces cerevisiae

  1987cited by this paper
• Normal stoichiometry of histone dimer sets is necessary for high fidelity of mitotic chromosome transmission.

  1986cited by this paper
• Interactions among the gypsy transposable element and the yellow and the suppressor of hairy-wing loci in Drosophila melanogaster

  1986cited by this paper
• Mutations at the suppressor of forked locus increase the accumulation of gypsy-encoded transcripts in Drosophila melanogaster

  1986cited by this paper
• Isolation of two genes that affect mitotic chromosome transmission in S. cerevisiae.

  1986cited by this paper
• Suppressors of SNF2 mutations restore invertase derepression and cause temperature-sensitive lethality in yeast.

  1986influential reference
• Molecular characterization of the Drosophila vermilion locus and its suppressible alleles.

  1986cited by this paper
• Ty elements transpose through an RNA intermediate.

  1985cited by this paper
• Reverse transcriptase activity and Ty RNA are associated with virus-like particles in yeast

  1985cited by this paper
• A detailed developmental and structural study of the transcriptional effects of insertion of the Copia transposon into the white locus of Drosophila melanogaster.

  1985cited by this paper
• Activation regions in a yeast transposon have homology to mating type control sequences and to mammalian enhancers.

  1985cited by this paper
• Forked, gypsys, and suppressors in Drosophila.

  1985cited by this paper
• Transposable element sequences involved in the enhancement of yeast gene expression.

  1985cited by this paper
• Ty element transposition: reverse transcriptase and virus-like particles.

  1985cited by this paper
• Effects of Ty insertions on HIS4 transcription in Saccharomyces cerevisiae

  1984cited by this paper
• Preferential integration of yeast transposable element Ty into a promoter region

  1984cited by this paper
• Sequences that regulate the divergent GAL1-GAL10 promoter in Saccharomyces cerevisiae

  1984cited by this paper
• Transformation of intact yeast cells treated with alkali cations.

  1984cited by this paper
• Mutations affecting Ty-mediated expression of the HIS4 gene of Saccharomyces cerevisiae.

  1984influential reference
• The SPT3 gene is required for normal transcription of Ty elements in S. cerevisiae.

  1984cited by this paper
• Ty-mediated gene expression of the LYS2 and HIS4 genes of Saccharomyces cerevisiae is controlled by the same SPT genes.

  1984cited by this paper
• Genomic sequencing.

  1984cited by this paper
• RNA from the yeast transposable element Ty1 has both ends in the direct repeats, a structure similar to retrovirus RNA.

  1983cited by this paper
• Eviction and transplacement of mutant genes in yeast.

  1983cited by this paper
• Drosophila melanogaster mutations suppressible by the suppressor of Hairy-wing are insertions of a 7.3-kilobase mobile element.

  1983cited by this paper
• A short nucleotide sequence required for regulation of HIS4 by the general control system of yeast.

  1983cited by this paper
• Dilute suppressor, a new suppressor gene in the house mouse.

  1983cited by this paper
• A rapid chromosome-mapping method for cloned fragments of yeast DNA.

  1983cited by this paper
• A new mapping method employing a meiotic rec-mutant of yeast.

  1982cited by this paper
• Genetic properties of chromosomally integrated 2 mu plasmid DNA in yeast.

  1982cited by this paper
• Expression of the ROAM mutations in Saccharomyces cerevisiae: involvement of trans‐acting regulatory elements and relation with the Ty1 transcription.

  1982cited by this paper
• Two differentially regulated mRNAs with different 5' ends encode secreted with intracellular forms of yeast invertase.

  1982cited by this paper
• Transposable elements associated with constitutive expression of yeast alcohol dehydrogenase II.

  1981cited by this paper
• Molecular cloning of chemotaxis genes and overproduction of gene products in the bacterial sensing system

  1981cited by this paper
• Yeast transformation: a model system for the study of recombination.

  1981cited by this paper
• Insertion of the eukaryotic transposable element Ty1 creates a 5-base pair duplication

  1980cited by this paper
• Genetic events associated with an insertion mutation in yeast.

  1980cited by this paper
• Mating signals control expression of mutations resulting from insertion of a transposable repetitive element adjacent to diverse yeast genes.

  1980cited by this paper
• DNA rearrangements associated with a transposable element in yeast.

  1980cited by this paper
• The origins of gene instability in yeast.

  1980cited by this paper
• A rapid alkaline extraction procedure for screening recombinant plasmid DNA.

  1979cited by this paper
• High-frequency transformation of yeast: autonomous replication of hybrid DNA molecules.

  1979cited by this paper
• Sterile host yeasts (SHY): a eukaryotic system of biological containment for recombinant DNA experiments.

  1979cited by this paper
• Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I.

  1977cited by this paper
• A genetic analysis of bacteriophage lambda head assembly.

  1976cited by this paper
• A genetic analysis of bacteriophage λ head assembly

  1976cited by this paper
• Interaction of morphogenetic genes of bacteriophage T4.

  1970cited by this paper
• A complementation analysis of the restriction and modification of DNA in Escherichia coli.

  1969cited by this paper

• Genetic dissection of transcription start site selection by RNA Polymerase II in Saccharomyces cerevisiae

  2025cites this paper
• The histone chaperone Spt6 controls chromatin structure through its conserved N-terminal domain.

  2025cites this paper
• A function of TPL/TBL1-type corepressors is to nucleate the assembly of the preinitiation complex

  2024cites this paper
• A conserved function of corepressors is to nucleate assembly of the transcriptional preinitiation complex

  2024cites this paper
• The Saccharomyces cerevisiae cell lysis mutant cly8 is a temperature-sensitive allele of ESP1

  2024cites this paper
• Insights into Spt6: a histone chaperone that functions in transcription, DNA replication, and genome stability.

  2023cites this paper
• Transcriptional regulation of FACT involves Coordination of chromatin accessibility and CTCF binding

  2023cites this paper
• The conserved histone chaperone Spt6 is strongly required for DNA replication and genome stability

  2023cites this paper
• Transcriptional elongation control in developmental gene expression, aging, and disease.

  2023cites this paper
• The conserved histone chaperone Spt6 facilitates DNA replication and mediates genome instability

  2022cites this paper
• Cooperation between intrinsically disordered and ordered regions of Spt6 regulates nucleosome and Pol II CTD binding, and nucleosome assembly

  2022cites this paper
• Transcription elongator SPT6L regulates the occupancies of the SWI2/SNF2 chromatin remodelers SYD/BRM and nucleosomes at transcription start sites in Arabidopsis

  2022cites this paper
• Spn1 and its dynamic interactions with Spt6, histones and nucleosomes.

  2022cites this paper
• The biochemical and genetic discovery of the SAGA complex.

  2020cites this paper
• Essential histone chaperones collaborate to regulate transcription and chromatin integrity

  2020influential citation
• The Chaperone FACT and Histone H2B Ubiquitination Maintain S. pombe Genome Architecture through Genic and Subtelomeric Functions.

  2019cites this paper
• Transcription-driven chromatin repression of Intragenic transcription start sites

  2019cites this paper
• Spt6 Association with RNA Polymerase II Directs mRNA Turnover During Transcription.

  2018cites this paper
• Induction of epigenetic variation in Arabidopsis by over-expression of DNA METHYLTRANSFERASE1 (MET1)

  2018cites this paper
• Casein kinase 2 mediated phosphorylation of Spt6 modulates histone dynamics and regulates spurious transcription

  2018cites this paper
• “ Gene Expression : The Journal of Liver Research ” Stat 3 regulates liver progenitor cell-driven liver regeneration in zebrafish

  2018cites this paper
• Transcription-driven Chromatin Repression of Intragenic Promoters

  2018cites this paper
• Stat3 Regulates Liver Progenitor Cell-Driven Liver Regeneration in Zebrafish.

  2018cites this paper
• Shaping the cellular landscape with Set2/SETD2 methylation

  2017cites this paper
• A MULTIFUNCTIONAL PLAYER IN THE CHROMATIN CONTEXT Submitted

  2017cites this paper
• Rôle de CK2 dans la dynamique de la chromatine et la précision transcriptionnelle

  2017cites this paper
• Développement d'outils bio-informatique pour l'étude de la transcription cryptique

  2017cites this paper
• The ribosome assembly gene network is controlled by the feedback regulation of transcription elongation

  2017cites this paper
• Nitrogen-status sensing in Arabidopsis

  2016cites this paper
• Relationships Between RNA Polymerase II Activity and Spt Elongation Factors to Spt- Phenotype and Growth in Saccharomyces cerevisiae

  2016influential citation
• The role of bZIPtranscription factors in the male gametophyte of Arabidopsis thaliana

  2016cites this paper
• Structure-Function Analysis of the Conserved Histone Chaperone Spt6

  2014cites this paper
• Factors controlling internal initiation of transcription at PRY3 in budding yeast

  2014cites this paper
• Factors controlling internal initiation of transcription at PRY 3 in budding yeast

  2014cites this paper
• Spt6 Regulates Intragenic and Antisense Transcription, Nucleosome Positioning, and Histone Modifications Genome-Wide in Fission Yeast

  2013cites this paper
• OP-NARE131001 1..12

  2013cites this paper
• Fission Yeast and Histone Modifications Genome-Wide in Transcription , Nucleosome Positioning , Spt 6 Regulates Intragenic and Antisense

  2013cites this paper
• Eukaryotic replisome components cooperate to process histones during chromosome replication.

  2013cites this paper
• A feed forward circuit comprising Spt6, Ctk1 and PAF regulates Pol II CTD phosphorylation and transcription elongation

  2013cites this paper
• UNCOVERING THE MECHANISM OF CHROMATIN ASSOCIATION OF THE PAF1 TRANSCRIPTION ELONGATION COMPLEX

  2013cites this paper
• Etude biochimique, structurale et fonctionnelle du complexe chaperonne d'histone/facteur d'élongation Spt6/Iws1

  2012cites this paper
• Gene Overexpression: Uses, Mechanisms, and Interpretation

  2012cites this paper
• Examining the contribution of chromatin and chromatin associated factors to transcription regulation

  2012cites this paper
• Chromatin and Transcription in Yeast

  2012cites this paper
• Identification of Mutant Versions of the Spt16 Histone Chaperone That Are Defective for Transcription-Coupled Nucleosome Occupancy in Saccharomyces cerevisiae

  2012cites this paper
• Histone Chaperones Spt6 and FACT: Similarities and Differences in Modes of Action at Transcribed Genes

  2011cites this paper
• Identification of Histone Mutants That Are Defective for Transcription-Coupled Nucleosome Occupancy

  2011cites this paper
• Mol . Cell . Biol . François Robert and Fred Winston Iva Ivanovska

  2011cites this paper
• Crystal structures of the S. cerevisiae Spt6 core and C-terminal tandem SH2 domain.

  2011cites this paper
• The Cellular Protein SPT6 Is Required for Efficient Replication of Human Cytomegalovirus

  2011cites this paper
• A Tandem SH2 Domain in Transcription Elongation Factor Spt6 Binds the Phosphorylated RNA Polymerase II C-terminal Repeat Domain (CTD)*

  2010cites this paper
• Histone chaperones, histone acetylation, and the fluidity of the chromogenome

  2010cites this paper
• Noncanonical Tandem SH2 Enables Interaction of Elongation Factor Spt6 with RNA Polymerase II*

  2010cites this paper
• Utilization Of Drosophila Hsp70 Gene For Identification Of Genuine Pol Ii Elongation Factors: Identification Of Spt6 As A Factor That Enhances The Elongation Rate Of Pol Ii In Vivo

  2010cites this paper
• Control of Chromatin Structure by Spt6: Different Consequences in Coding and Regulatory Regions

  2010cites this paper
• Deletion of Candida albicans SPT6 is not lethal but results in defective hyphal growth.

  2010cites this paper
• Structure and biological importance of the Spn1-Spt6 interaction, and its regulatory role in nucleosome binding.

  2010cites this paper
• Proteome-wide prediction of acetylation substrates

  2009cites this paper
• Structure and in vivo requirement of the yeast Spt6 SH2 domain.

  2009cites this paper
• Structure and requirement of the Spt6 SH2 domain and an in vitro system to test the "torpedo model" of transcription termination

  2009cites this paper
• Histone chaperones: 30 years from isolation to elucidation of the mechanisms of nucleosome assembly and disassembly

  2008cites this paper
• Factors controlling internal initiation of transcription at PRY3 in budding yeast

  2008cites this paper
• Roles for Ctk1 and Spt6 in Regulating the Different Methylation States of Histone H3 Lysine 36

  2008cites this paper
• The role of the SPT6 chromatin remodeling factor in zebrafish embryogenesis.

  2007cites this paper
• The Bur1 Cyclin-Dependent Protein Kinase Is Required for the Normal Pattern of Histone Methylation bySet2

  2006cites this paper
• Evidence That Spt10 and Spt21 of Saccharomyces cerevisiae Play Distinct Roles in Vivo and Functionally Interact With MCB-Binding Factor, SCB-Binding Factor and Snf1

  2005cites this paper
• Interaction between Transcription Elongation Factors and mRNA 3′-End Formation at the Saccharomyces cerevisiae GAL10-GAL7 Locus*

  2005cites this paper
• Identification of the Linker-SH2 Domain of STAT as the Origin of the SH2 Domain Using Two-dimensional Structural Alignment*

  2004cites this paper
• Elongation by RNA polymerase II: the short and long of it.

  2004cites this paper
• Multiple roles for Saccharomyces cerevisiae histone H2A in telomere position effect, Spt phenotypes and double-strand-break repair.

  2003cites this paper
• Transcription Elongation Factors Repress Transcription Initiation from Cryptic Sites

  2003cites this paper
• Identifying phase-specific genes in the fungal pathogen Histoplasma capsulatum using a genomic shotgun microarray.

  2003cites this paper
• SPT 5 , an Essential Gene Important for Normal Transcription in Saccharomyces cerevisiae , Encodes an Acidic Nuclear Protein with a Carboxy-Terminal Repeat

  2003influential citation
• SP 7 Y 5 , the Gene Encoding the Yeast TATA B inding Factor TFIID , Is Required for Normal Transcription Initiation In V ivo

  2003cites this paper
• The Paf1 complex physically and functionally associates with transcription elongation factors in vivo

  2002cites this paper
• Identification of a New Class of Negartive Regulators Affecting Sporulation-Specific Gene Expression in Yeast

  2002cites this paper
• Isolation and Identification of Genes Activating UAS 2-Dependent ADH 2 Expression in Saccharomyces cerevisiae

  2002cites this paper
• Yeast histone deposition protein Asf1p requires Hir proteins and PCNA for heterochromatic silencing.

  2001cites this paper
• Corepressor proteins and control of transcription in yeast.

  2001cites this paper
• Functional Interaction between Pleiotropic Transactivator pUL69 of Human Cytomegalovirus and the Human Homolog of Yeast Chromatin Regulatory Protein SPT6

  2000cites this paper
• Chromatin and transcription in Saccharomyces cerevisiae.

  1999cites this paper
• Spe3, which encodes spermidine synthase, is required for full repression through NRE(DIT) in Saccharomyces cerevisiae.

  1998influential citation
• Molecular Genetics of the RNA Polymerase II General Transcriptional Machinery

  1998influential citation
• The yeast protein complex containing cdc68 and pob3 mediates core-promoter repression through the cdc68 N-terminal domain.

  1998influential citation
• Functional dissection of yeast Hir1p, a WD repeat-containing transcriptional corepressor.

  1998cites this paper
• Characterization of the CP Complex, an Abundant Dimer of Cdc68 and Pob3 Proteins That Regulates Yeast Transcriptional Activation and Chromatin Repression*

  1998cites this paper
• The C-Terminal Domain of Sin1 Interacts with the SWI-SNF Complex in Yeast

  1998cites this paper
• Genetic redundancy between SPT23 and MGA2: regulators of Ty-induced mutations and Ty1 transcription in Saccharomyces cerevisiae

  1997cites this paper
• Hir1p and Hir2p function as transcriptional corepressors to regulate histone gene transcription in the Saccharomyces cerevisiae cell cycle

  1997cites this paper
• Identification of RTF1, a novel gene important for TATA site selection by TATA box-binding protein in Saccharomyces cerevisiae

  1997cites this paper
• Mutations in the SPT4, SPT5, and SPT6 genes alter transcription of a subset of histone genes in Saccharomyces cerevisiae.

  1996cites this paper
• Isolation and identification of genes activating UAS2-dependent ADH2 expression in Saccharomyces cerevisiae.

  1996cites this paper
• Epigenetic effects on yeast transcription caused by mutations in an actin-related protein present in the nucleus.

  1996cites this paper
• Faithful chromosome transmission requires Spt4p, a putative regulator of chromatin structure in Saccharomyces cerevisiae

  1996cites this paper
• Functional analysis of histones H2A and H2B in transcriptional repression in Saccharomyces cerevisiae

  1996cites this paper
• Genetic and biochemical characterization of the ADAs, a transcriptional adaptor complex

  1996cites this paper
• Evidence That Spt6p Controls Chromatin Structure by a Direct Interaction with Histones

  1996cites this paper
• Enhancement of human estrogen receptor activity by SPT6: a potential coactivator.

  1995cites this paper
• Transcriptional and posttranslational regulation of the general amino acid permease of Saccharomyces cerevisiae

  1995cites this paper
• Complilation and characteristics of dedicated transcription factors in Saccharomyces cerevisiae

  1995cites this paper